Pediatric Hematology-Oncology in Countries with Limited Resources: A Practical Manual

 Hematology, Oncology, Pediatrics  Comments Off on Pediatric Hematology-Oncology in Countries with Limited Resources: A Practical Manual
Dec 292018
 

Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. Pediatric Hematology-Oncology in Countries with Limited Resources is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries.​
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Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease

 Hematology  Comments Off on Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease
Dec 222018
 

Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day. Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems. Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format Includes and illustrates the WHO Classification of Hematologic Malignancies Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.
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Consultative Hemostasis and Thrombosis – 4th Edition (October 2018 Release)

 Hematology  Comments Off on Consultative Hemostasis and Thrombosis – 4th Edition (October 2018 Release)
Dec 152018
 

With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that’s new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors’ position that correct treatment begins with correct diagnosis. This trusted resource by Drs. Craig S. Kitchens, Craig M. Kessler, Barbara A. Konkle, Michael B. Streiff, and David A. Garcia is designed for rapid reference and critical decision making at the point of care.

  • Emphasizes real-world problems and solutions, with quick access to concise descriptions of each condition, associated symptoms, laboratory findings, differential diagnosis, and treatment.
  • Features a user-friendly design, full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.
    • Provides thorough updates on core information on hemostasis and thrombosis, including deep venous thrombosis (DVT), pulmonary embolisms, hypercoagulability, thrombocytopenia, von Willenbrand disease, and more.
    • Covers new treatment information on hemophilia A and B.
    • Contains new chapters on hereditary hemorrhagic telangiectasia, hemolytic uremic syndrome, and paroxymal nocturnal hemoglobinuria.
    • Two new editors, Dr. Michael B. Streiff and Dr. David A. Garcia, offer fresh perspectives and valuable experience.

  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

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Haploidentical Transplantation: Concepts & Clinical Application

 Hematology  Comments Off on Haploidentical Transplantation: Concepts & Clinical Application
Nov 102018
 

In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.

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Homeopathy: Materia Medica Vol. 4

 Hematology  Comments Off on Homeopathy: Materia Medica Vol. 4
Oct 222018
 

(Constitutional Pictures of Pulsatilla, Calcarea Carbonica, Arsenicum, Aconitum, Mancinella, Ignatia, Sepia, Silica, Lilium Tigrinum, Asafoetida, Moschus, Cimicifuga, Nux Vomica, Psorinum, Hyoscyamus, Stramonium, Cannabis Indica, Tarentula Hispanica, Palladium and 14 less frequent ones)

Imagine that a certain Science has managed to identify and describe, in details, all the existing human personalities, all the existing human types: mode of thinking, special emotions and mode of behavior; how, each personality, tends to behave in affairs, sexuality, family, politics, religion, profession, etc.; in addition, what kind of physical and psychological diseases, each personality, tends to develop.

Wouldn’t that be wonderful!
Moreover, imagine that this identification has been done in an objective and scientific way. That is, not only through clinical observation, but, on top of that, through the scientific methodology of the Double Blind Trial. To add, imagine that this Science has succeeded in finding a way to minimize the extreme features of each personality, therefore, contributing to the prevention, as well as, to the cure of the above mentioned physical and psychological diseases, in the most harmless and natural way.

Well, this isn’t some kind of imagination! This is a reality! It’s the reality of the everyday clinical practice of the Homeopathic Medicine and, especially, of the Classical Miasmatic Constitutional Homeopathy, developed by the author. In the volumes of this book, the writer describes in a scientific, yet fascinating and simple way, the Constitutional Pictures that affect all of us. Would you like to know, in the deepest way, yourself, your companion, children, parents and friends? Then, you, definitely, must read this book!

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Neoplastic Hematopathology: Experimental and Clinical Approaches

 Hematology, Pathology  Comments Off on Neoplastic Hematopathology: Experimental and Clinical Approaches
Oct 142018
 

Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias.

Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation.

Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.

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Heparin-Induced Thrombocytopenia, Fifth Edition

 Hematology  Comments Off on Heparin-Induced Thrombocytopenia, Fifth Edition
Oct 032018
 

Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most frequent and devastating adverse drug reactions encountered by physicians. This thoroughly updated fifth edition from international experts Professors Warkentin and Greinacher is the gold standard for accurate diagnosis and management of this condition. Identifying key signs and symptoms and providing clear intervention strategies―including the use of alternative anticoagulants to manage critical circumstances―this is an essential resource for all clinicians and a “must” for hematology consultants.

Heparin-Induced Thrombocytopenia, Fifth Edition explores:

Clinical and laboratory studies on HIT
The immune basis and pathogenesis, animal models, and laboratory testing for HIT antibodies
Clinical features, differential diagnosis, scoring systems, and frequency of HIT in diverse clinical settings, including pediatric patients
Evidence-based guidelines for recognition, treatment, and prevention
Actions that should and should not be taken after the identification of HIT
Traditional and novel pharmacotherapies, current dosing guidelines, and the advantages and limitations of alternative anticoagulants
Selection criteria from a variety of new treatment options, helping physicians determine which of these agents are safe and effective for their patients

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Camel Clinical Biochemistry and Hematology

 Hematology  Comments Off on Camel Clinical Biochemistry and Hematology
Sep 252018
 

This work brings together a wealth of data regarding the reference values and factors of variation in biochemical parameters used by camel veterinarians and scientists to determine these animals’ nutritional and clinical status. It also explores several technical aspects involved in determining these parameters, sampling procedures, and essential elements in the interpretation of the results. Though many texts are available on small and large ruminants, much less is known about species confined to the marginal zones of tropical and Mediterranean countries, such as camels. This book addresses precisely this research gap, on the one hand by presenting an extensive review of the literature, and on the other by synthesizing the outcomes of the authors’ numerous previous works.
In veterinary medicine, blood tests to help diagnose diseases in cattle were first proposed nearly a century ago, but were mainly developed in the 1960s, initially at specialized research or veterinary services laboratories, and eventually, with the advent of new equipment and the miniaturization of the analyzers, finding their way into veterinarians’ cabinets. Beyond their diagnostic value, veterinary surgeons and zootechnicians also speculated on the potential use of blood tests to evaluate animals’ nutritional status. Thus, a whole range of analyses are now proposed to the stakeholders responsible for animal health. Such analyses could help to define a metabolic profile, which would offer a valuable decision-making tool for experts and researchers alike.

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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

 Hematology  Comments Off on WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
Sep 172018
 

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised Fourth Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis, and predictive factors.This classification, prepared by 132 authors from 23 countries, contains about 1300 color images and tables and more than 4500 references.
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Small Molecules in Hematology (Recent Results in Cancer Research) 3rd Editions

 Hematology, Oncology  Comments Off on Small Molecules in Hematology (Recent Results in Cancer Research) 3rd Editions
Sep 132018
 

This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

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