Small Molecules in Oncology (Recent Results in Cancer Research) 3rd Edition

 Oncology  Comments Off on Small Molecules in Oncology (Recent Results in Cancer Research) 3rd Edition
Sep 182018
 

This book, written by respected experts, discusses in detail the latest developments in targeted oncology therapy using small molecules. It covers a wide range of small molecules, including tyrosine kinase inhibitors, mTOR, MEK, PARP, and multikinase inhibitors, as well as cell cycle and NTRK interacting agents. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

GET IT FREE HERE

http://nitroflare.com/view/CE5C27E51E8C32E/3319914413.pdf

ALTERNATIVE LINK

https://filejoker.net/zk80sfevi5pg

Share Button

Interleukin-2 and Killer Cells in Cancer

 Oncology  Comments Off on Interleukin-2 and Killer Cells in Cancer
Sep 172018
 

This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Management of Advanced Prostate Cancer

 Oncology  Comments Off on Management of Advanced Prostate Cancer
Sep 152018
 

This textbook summarizes the state of the art in the management of locally advanced and metastatic prostate cancer with the aim of providing the knowledge required for optimal treatment decision making in individual cases. Readers will find comprehensive coverage of the latest developments in surgery, radiotherapy, androgen deprivation therapy (ADT), chemotherapy, and immunotherapy. The role of the hormonal therapies abiraterone and enzalutamide and docetaxel-based chemotherapy in castration-resistant prostate cancer and hormone-sensitive metastatic disease is carefully evaluated. Among the other therapies discussed are LHRH agonists and antagonists, cabazitaxel, radium-223, and various novel agents still under clinical trials.
The section on surgical approaches addresses, among other topics, the use of robot-assisted radical prostatectomy, pelvic lymphadenectomy, and the benefits of adjuvant and neoadjuvant therapy. The current role of external beam radiotherapy, alone or in combination with ADT and brachytherapy, for locally advanced disease is reviewed. Management of Advanced Prostate Cancer will be a valuable resource for practitioners at all levels of expertise.

GET IT FREE HERE

http://nitroflare.com/view/177102F11CDDE49/9811069425.epub

http://nitroflare.com/view/45ED25F95183599/9811069425.pdf

ALTERNATIVE LINK

https://filejoker.net/1o61fvppj51j

https://filejoker.net/7au0w8p0tgt4

Share Button

Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R

 Oncology, Statistics  Comments Off on Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R
Sep 152018
 

Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with time-to-event endpoints are often limited to the exponential model or proportional hazards model. In practice, however, those model assumptions may not be satisfied for long-term survival trials.

This book is the first to cover comprehensively the many newly developed methodologies for survival trial design, including trial design under the Weibull survival models; extensions of the sample size calculations under the proportional hazard models; and trial design under mixture cure models, complex survival models, Cox regression models, and competing-risk models. A general sequential procedure based on the sequential conditional probability ratio test is also implemented for survival trial monitoring. All methodologies are presented with sufficient detail for interested researchers or graduate students.

GET IT FREE HERE

http://nitroflare.com/view/B262641D10ED7CF/1138033227.pdf

ALTERNATIVE LINK

https://filejoker.net/er4oy0er73a9

Share Button

Pathology of Female Cancers: Precursor and Early-Stage Breast, Ovarian and Uterine Carcinomas

 Oncology, Pathology  Comments Off on Pathology of Female Cancers: Precursor and Early-Stage Breast, Ovarian and Uterine Carcinomas
Sep 132018
 

This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, WHO Classification of Tumours of the Breast was revised and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs was revised. In these latest versions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awareness of the specific pathogenesis of tumors in female patients. Although some of these issues are still controversial, several paradigm shifts should be understood by medical scientists. Thus researchers, diagnostic pathologists, and clinicians must share current information about what is taking place in the field and what the next issue to resolve is.

GET IT FREE HERE

http://nitroflare.com/view/186F34F054E6E06/9811086052.epub

http://nitroflare.com/view/875D34220E4EAAA/9811086052.pdf

ALTERNATIVE LINK

https://filejoker.net/hih8d4zuuqfg

https://filejoker.net/5zn3999jrb33

Share Button

Small Molecules in Hematology (Recent Results in Cancer Research) 3rd Editions

 Hematology, Oncology  Comments Off on Small Molecules in Hematology (Recent Results in Cancer Research) 3rd Editions
Sep 132018
 

This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

GET IT FREE HERE

http://nitroflare.com/view/668B172874D92EB/3319914383.pdf

ALTERNATIVE LINK

https://filejoker.net/65wf9nkt0yk4

Share Button

Physicians’ Cancer Chemotherapy Drug Manual 2018 (18th edition)

 Oncology  Comments Off on Physicians’ Cancer Chemotherapy Drug Manual 2018 (18th edition)
Sep 112018
 

Completely revised and updated for 2018, the Physicians’ Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens-both on- and off-label-for the treatment of all the major cancers.

GET IT FREE HERE

http://nitroflare.com/view/978BB4B4F4310DB/1284144968.pdf

ALTERNATIVE LINK

https://filejoker.net/6fg3p82ntdo9

Share Button

Cancer

 Oncology  Comments Off on Cancer
Sep 112018
 

In life-threatening forms of cancer, cells stop working correctly, grow, divide, and spread throughout the body in harmful ways. These diseases impact the lives of many people, directly for those diagnosed and indirectly for the friends and families of those diagnosed. So many distinct forms of cancer with multiple unique diagnostic tools and approaches to treatment can be overwhelming for those diagnosed and those supporting them. Historical struggles with cancer can create a hopeless perception of disease prognosis, but advances in cancer diagnosis and treatment mean that many cancers can be well managed and even cured. This book discusses four types of cancer: skin, lung, breast, and prostate cancer. Wrestling with a diagnosis of one of these cancers can be complicated by the variety of treatment choices available and the unique medical history associated with both the patient and the cancer. The complexity of diagnosis and treatment requires that each cancer be considered a distinct disease, with some underlying common features. The author describes these common features and then discusses each cancer in terms of symptoms, diagnosis, causes, treatments, and future advances.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Breast Cancer: A Guide to Detection and Multidisciplinary Therapy

 Oncology  Comments Off on Breast Cancer: A Guide to Detection and Multidisciplinary Therapy
Sep 092018
 

Michael H. Torosian, MD, and a panel of physicians and clinical researchers critically synthesize the wide variety of treatment options available to create a state-of-the-art reference for the management of breast cancer patients. Writing from a multidisciplinary perspective, these authoritative contributors review in the light of the most recent findings the major clinical aspects of breast cancer, including, epidemiology and risk factors, breast imaging, biopsy techniques, breast-conserving surgery and reconstruction, mastectomy, and the latest developments in radiation, hormonal, and chemotherapy. Their expert discussion also addresses special clinical situations (adjuvant chemotherapy, axillary adenopathy as initial presentation, breast cancer during pregnancy, and sarcoma and lymphoma of the breast) and explains current clinical controversies (breast-conserving surgery without radiation therapy, axillary lymph node management, and management of internal mammary lymph nodes).

GET IT FREE HERE

http://nitroflare.com/view/953A8D413CC4C14/0896038394_1617372161.pdf

ALTERNATIVE LINK

https://filejoker.net/0u1u2sheik6g

Share Button

Manual of Clinical Oncology 8th Edition

 Oncology  Comments Off on Manual of Clinical Oncology 8th Edition
Sep 052018
 

Concise, portable, and packed with essential information, Manual of Clinical Oncology is an indispensable resource for understanding basic science, clinical findings, and available technology as they relate to the diagnosis and management patients with cancer. The practical format provides high-yield content useful for participating in rounds ad making diagnostic and therapeutic decisions at the bedside. Edited by Dr. Bartosz Chmielowski and Dr. Mary Territo, both from UCLA School of Medicine, this eighth edition carries on the tradition of excellence set forth by longtime editor Dr. Dennis Casciato.

GET T FREE HERE

http://nitroflare.com/view/B6FA582C9C173E5/1496349571.pdf

ALTERNATIVE LINK

https://filejoker.net/2kfr5a898vl2

Share Button