MRI Manual of Pelvic Cancer, Second Edition

 Oncology  Comments Off on MRI Manual of Pelvic Cancer, Second Edition
Jul 232020
 

Written by internationally renowned authors, this title is an invaluable reference for all those required to report on MR examinations, with accurate cancer staging aided by the extensive use of high quality MR images of pelvic cancer.
Each chapter gives a short account of every disease and a set of images demonstrating the tumour, node and metastasis stages, based on the 2010 UICC/AJCC staging system.

A highly useful resource, this guide also:

Introduces pelvic cancer staging, MRI technique, and pelvic anatomy

Presents a comprehensive set of state-of-the-art images of the various pelvic cancers

Contains illustrations of recurrent disease and appearances following chemo-radiotherapy

Discusses imaging before exenterative surgery and the imaging of metastatic disease within the pelvis

What’s new to this edition:

New techniques in a number of pelvic cancers, including cervical, endometrial, ovarian and vaginal cancer, such as MR diffusion, MR spectroscopy and Dynamic Contrast Imaging

Image findings post chemoradiation for cervical, rectal and bladder cancer

New section on image findings in brachytherapy for prostate cancer

Brand new chapter on penile cancer

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https://nitroflare.com/view/94380CB3BFA433C/1841846767.pdf

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STAT Inhibitors in Cancer

 Oncology  Comments Off on STAT Inhibitors in Cancer
Jul 232020
 

This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.
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Oral Cancer

 Oncology  Comments Off on Oral Cancer
Jul 222020
 

This is a concise, informed and practical manual detailing the cause, prevention and interventional treatment of oral cancerthe deadliest of oral diseases. In the 21st century, oral cancer remains a lethal and deforming disease exhibiting rising incidence of epidemic proportions, particularly in younger patients, and is of global significance with over 300,000 new cases presenting each year. Despite advances in diagnosis and management, half of all patients die within five years. Even following successful initial treatment, long-term prognosis is compromised by the presentation of advanced tumours and development of widespread, multi-focal disease throughout the mouth and upper aero-digestive tract. The transformation of normal mouth lining into potentially malignant and subsequently malignant tissue is a complex, multistep and multifactorial process in which accumulated genetic alterations, often instigated by overuse of tobacco and alcohol, disrupt the normal functioning of oral epithelial cells. Unfortunately, there is considerable public ignorance regarding oral cancer, and it is imperative for disease prevention to raise awareness of the causes and symptoms of the disease, especially in those populations most at-risk of cancer. This book provides pragmatic strategies to improve both prevention and treatment intervention. Spanning nearly 40 years of clinical investigation, it reviews the biological basis of oral cancer, outlines primary, secondary and tertiary preventive strategies and describe a pragmatic treatment intervention protocol that specifically utilizes the potentially malignant window to identify malignant disease at the earliest possible stage and intervention to stop the oral cancer clock and halt the progression of this deadliest of oral diseases.

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https://nitroflare.com/view/CDABF63576283BB/1527522792.pdf

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Holland-Frei Cancer Medicine, 8 edition

 Oncology  Comments Off on Holland-Frei Cancer Medicine, 8 edition
Jul 192020
 

The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice. In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging, and therapy. The book is a testament to the editorial panel s creed–that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology.

Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices. Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue. The 137 tightly focused chapters are organized into 5 sections: CARDINAL MANIFESTATIONS OF CANCER; SCIENTIFIC FOUNDATIONS OF CANCER; PRINCIPLES OF CANCER DIAGNOSIS; PRINCIPLES OF THERAPEUTIC MODALITIES; PRINCIPLES OF MULTIDISCIPLINARY MANAGEMENT

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Gynaecological Oncology, Second Edition

 Ob/Gynae, Oncology  Comments Off on Gynaecological Oncology, Second Edition
Jul 152020
 

Providing a thorough and up-to-date overview of the full range of gynaecological cancers, Gynaecological Oncology is a concise introduction, particularly useful for trainees working towards postgraduate examinations. The first section includes introductory chapters on epidemiology, screening and prevention, imaging, pathology, surgery, radiation therapy, chemotherapy, and palliation.

The second part of the book covers the gynaecological cancer types in turn; each chapter following a similar format looking at clinical issues, staging, and principles of management. Where appropriate, flow-charts and diagrams are used to help the reader assimilate complex information. A chapter is devoted to decision-making, addressing those issues clinicians and women face when deciding on optimal management in given clinical scenarios. The book is practically based and is enhanced by highlighting learning points, management algorithms and clinical images. This is an invaluable resource for all doctors and allied health professionals dealing with women with gynaecological cancers.

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https://nitroflare.com/view/9776630AE7E8072/0521730244.pdf

 

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Tumor Suppressor Genes in Human Cancer (Cancer Drug Discovery and Development)

 Oncology  Comments Off on Tumor Suppressor Genes in Human Cancer (Cancer Drug Discovery and Development)
Jul 152020
 

David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describing the broad roles of tumor suppressors from a perspective based in molecular biology and genetics, the authors detail the major suppressors and the pathways they regulate, including cell cycle progression, stress responses, apoptosis, and responses to DNA damage. Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already beginning to revolutionize cancer target elucidation, drug discovery, and treatment design.

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https://nitroflare.com/view/E06D53426FD4626/0896038076_Tumor.pdf

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Molecular Biochemical Aspects of Cancer

 Oncology  Comments Off on Molecular Biochemical Aspects of Cancer
Jul 072020
 

This book discusses the role of genes, oncogenes, anti-oncogenes, free radicals, PUFAs, anti-oxidants, lipid peroxidation process, telomere, and angiogenesis on the origin of cancer, cell proliferation, and cancer in general. It includes a broad introduction to cancer cells; genes, oncogenes, and anti-oncogenes; and free radicals. In later chapters, it discusses in depth the relationship among free radicals, lipid peroxidation and anti-oxidants in cell proliferation. It also discusses aerobic and anaerobic metabolism and their relationship to cancer, as well as the Warburg effect and its potential in the development of new targets for cancer management. Based on these and other evidences, Molecular Biochemical Aspects of Cancer introduces a novel concept that suggests that selective enhancement of free radical generation in tumor cells could form a strategy to induce apoptosis of cancer cells employing bioactive lipids. It presents a new method of treatment of cancer using in vitro, in vivo and clinical data. This book will interest oncologists, scientists, molecular biologists, life scientists.

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https://nitroflare.com/view/D44D272E4FF0E78/1071607391.pdf

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Oncology Clinical Trials: Successful Design, Conduct, and Analysis

 Oncology  Comments Off on Oncology Clinical Trials: Successful Design, Conduct, and Analysis
Jun 252020
 

Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the marketplace, and expand the horizon of contemporary thinking about cancer biology. A poorly done trial does little to advance the field or guide clinical practice, consumes precious clinical and financial resources and challenges the validity of the ethical contract between investigators and the volunteers who willingly give their time and effort to benefit future patients. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives,

Oncology Clinical Trials, provides a comprehensive guide for both early-career and senior oncology investigators into the successful design, conduct and analysis of an oncology clinical trial.

Oncology Clinical Trials covers how to formulate a study question, selecting a study population, study design of Phase I, II, and III trials, toxicity monitoring, data analysis and reporting, use of genomics, cost-effectiveness analysis, systemic review and meta-analysis, and many other issues. Many examples of real-life flaws in clinical trials that have been reported in the literature are included throughout. The book discusses clinical trials from start to finish focusing on real-life examples in the development, design and analysis of clinical trials.

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https://nitroflare.com/view/62545000D2B64C3/1933864389.pdf

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Breast Cancer: A Multidisciplinary Approach to Diagnosis and Managmenet

 Oncology  Comments Off on Breast Cancer: A Multidisciplinary Approach to Diagnosis and Managmenet
Jun 232020
 

Over the course of the last decade, the treatment of breast cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of breast cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, fertility radiation, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment.

Breast Cancer: A Multidisciplinary Approach to Diagnosis and Management, by a multidisciplinary team of authors representing a range of disciplines, is a review for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of breast cancer. Breast Cancer: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of breast cancer and describes an approach for optimal multidisciplinary care for women are at higher risk of or who have been diagnosed with breast cancer.

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https://nitroflare.com/view/C1BA82D8AED1CF5/1933864443.pdf

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Small Cell Carcinomas: Causes, Diagnosis and Treatment

 Oncology, Respiratory Medicine  Comments Off on Small Cell Carcinomas: Causes, Diagnosis and Treatment
Jun 152020
 

Small cell carcinoma is a type of cancer that almost always effects the lungs. Small cell carcinoma is almost always caused by smoking, but exposure to large amounts of asbestos is also a risk factor. Small cell carcinoma usually effects men more than women and while not a common type of lung cancer, is considered very deadly. Unlike other types of cancer, small cell carcinoma is not staged on a numerical scale but rather as simply limited or extensive. Limited stage refers to cancer that is contained within the lungs or bronchial tubes only. Extensive stage indicates the cancer has spread to areas outside of the chest. Limited stage small cell carcinoma is rare because it is usually not diagnosed until it has become extensive. Symptoms of small cell carcinoma lung cancer are similar to other types of lung cancer and may include chronic coughing, wheezing, shortness of breath, sputum production, and possibly weight loss. This new book gathers the latest research from around the globe on this disease.
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