Oncolytic Viruses (Methods in Molecular Biology, v797)

 Oncology  Comments Off on Oncolytic Viruses (Methods in Molecular Biology, v797)
Jun 172019
 

Since the first report of an engineered oncolytic virus, there has been a continuing and steady increase of interest in the field, and while bench research remains vital for the translation of research in this field, its success depends on breakthroughs in clinical studies. Oncolytic Viruses: Methods and Protocols describes the construction and purification of capsid-modified adenoviruses as well as oncolytic adenoviruses, presents protocols for many individual virus species including engineering and preparation of oncolytic HSV, propagation, purification, and in vivo testing of oncolytic VSV, details properties of oncolytic reovirus and NDV, and describes the generation and testing of next generation of oncolytic vaccinia virus. As the host immune system plays a critical role in determining efficacy of oncolytic viruses, two chapters are devoted to the study of immune response. Recent advances in stem cell research have led the field in two distinct directions: the use of stem cells as carrier vehicles for oncolytic viruses and the targeting of cancer stem cells. As such, the volume describes the use of explant tissue samples from patients to potentially provide useful information predicting responses prior to clinical translation. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Oncolytic Viruses: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of this essential and vital field.
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Pediatric Oncologic Pharmacy: A Complete Guide to Practice

 Oncology, Pediatrics, Pharmacology  Comments Off on Pediatric Oncologic Pharmacy: A Complete Guide to Practice
Jun 112019
 

There are few publications about chemotherapy in children, and none of them is a book aimed at pharmacists. Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice. Pharmacists who work in pediatric oncology area do not have a book directed at them; none of the oncopediatric books addresses topics unique to pharmacy ― such as manipulation of cytotoxic drugs for children, analysis of oncopediatric prescriptions, clinical pharmacy in oncopediatrics, pharmaceutical care in oncopediatric area, and other subjects that are of exclusive interest to these professionals, but no less essential for a therapy of excellence. As for this need, the purpose of this book is to be a guideline for all subjects that pediatric oncology pharmacists need to know to work in this area. It will be an essential guide to pediatric oncology pharmacists, clinical pharmacists, pharmaceutical residents who work with drug therapy in children and pharmaceutical researchers. It will be a pocket guide to assist in daily practice, and it will be essential to Pediatric Oncology/ Hematology Institutions. The essential propose of this book is to be the first one focusing pediatric oncology for pharmacists.
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Gastric Cancer

 Gastroenterology/Hepatology, Oncology, Radiology  Comments Off on Gastric Cancer
Jun 092019
 

Gastric adenocarcinoma is the second most common cancer worldwide. It is usually diagnosed at a late stage and prognosis is poor; even with modern diagnostic and treatment methods the 5-year survival is only 10%. Improvements in overall patient survival can only be achieved by earlier diagnosis and by tailored therapeutic strategies based on tumor type, location and stage at presentation.

This volume provides a state-of-the-art, integrated diagnostic and therapeutic approach to patient management. The role of the upper GI series, endoscopy, endoscopic ultrasound, MDCT, MRI, and PET/CT in the diagnosis, staging and follow-up of patients with gastric cancer is emphasized. The relative strengths and limitations of these diagnostic examinations will be presented in context with the most recent epidemiologic, pathologic, and therapeutic concepts regarding this tumor. With expert contributions from members of an international multidisciplinary team, this is an invaluable guide to the diagnosis and management of gastric malignancies.

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Cancer-Free with Food: A Step-by-Step Plan with 100+ Recipes to Fight Disease

 Oncology  Comments Off on Cancer-Free with Food: A Step-by-Step Plan with 100+ Recipes to Fight Disease
Jun 062019
 

Supported by the powerhouse team behind The Truth About Cancer, best-selling natural-health author Liana Werner-Gray offers a simple yet comprehensive guide to nutrition for those who have been diagnosed with cancer.
Food is medicine. By now, this important message has made its way from holistic circles to the mainstream. To ward off cancer and decrease its risk, meals specially formulated to nourish, soothe, and fortify can be an important part of treatment.

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Communicating with Cancer Patients

 Oncology  Comments Off on Communicating with Cancer Patients
Jun 052019
 

Published in association with European Society of Medical Oncology, this volume is designed for trainee oncologists, oncology nurses, and those working with cancer patients on a day-to-day basis.

Focusing on the “soft skills” required in communicating with patients, the book includes topics such as the aetiology of cancer, diagnosis and staging, and explaining the purpose of treatment, including chemotherapy, hormone treatment, and immunological and gene-based therapies. It also discusses patient support groups, monitoring remission, and relapse. The book is written by UK oncologists but has international application

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Caveolins in Cancer Pathogenesis, Prevention and Therapy

 Oncology  Comments Off on Caveolins in Cancer Pathogenesis, Prevention and Therapy
Jun 042019
 

Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. They have been shown to play an important role in the pathogenesis of multiple cancers. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.
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QuickFACTS Advanced Cancer

 Oncology  Comments Off on QuickFACTS Advanced Cancer
Jun 032019
 

Although advanced cancer is not likely to be cured, it can frequently be controlled, and this book emphasizes that all patients should be well-informed decision-makers in planning their own treatment. Covering everything from risk factors to living well after cancer treatment, this pocket-sized reference provides critical questions to ask your healthcare team, is updated with the latest patient treatment guidelines, and includes an advanced dictionary of cancer-related terms.
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Atlas of Procedures in Surgical Oncology With Critical, Evidence-based Commentary Notes

 Oncology  Comments Off on Atlas of Procedures in Surgical Oncology With Critical, Evidence-based Commentary Notes
Jun 032019
 


This unique book presents a series of concisely written technical notes on common procedures in surgical oncology. Each operation is illustrated with pictures framing precise technical points. The book is accompanied by a CD-ROM that includes video clips of the procedures.

Written by top European experts, this volume will provide an invaluable resource for young surgical oncologists to familiarize with technical details, develop a critical approach and expand their surgical skills. It will also be a useful source of reference for medical oncologists, radiologists, radiotherapists and nurses, as well as final-year medical students.

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Cancer and its Management, 7 edition

 Oncology, Uncategorized  Comments Off on Cancer and its Management, 7 edition
May 312019
 

Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management.

The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revised new editions of this standard and well-received cancer text for audiences in the UK and abroad. Oncology is a very rapidly changing speciality, with many new treatments and even treatment modalities coming on stream with bewildering speed. Besides a thorough general updating of the text, figures, and tables, the new seventh edition adds a new chapter on Molecular Targeted Therapy, making the book 30 chapters in total. This accessible and practical resource is invaluable to trainees and specialists alike in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine.

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Methionine Dependence of Cancer and Aging: Methods and Protocols

 Oncology  Comments Off on Methionine Dependence of Cancer and Aging: Methods and Protocols
May 302019
 

This book explores the methionine dependence of cancer and its effects on aging, a great story of science that is not widely known. The chapters in this book describe the discovery of methionine dependence of cancer; the molecular basis for the increased methionine demand of cancer cells and tumors; the clinical application of methionine dependence of cancer in PET imaging with [11C]methionine; the development of methioninases as cancer drugs; the anti-aging and anti-diabetes effects of methionine restriction; and the future of targeting methionine in the body for the elimination of cancer and for the extension of a healthy life-span. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Methionine Dependence of Cancer and Aging: Methods and Protocols is an important resource for researchers and scientists wishing to pursue this exciting and vital area of study.”

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