Clinical Scenarios in Surgical Oncology

 Oncology, Surgery  Comments Off on Clinical Scenarios in Surgical Oncology
Oct 152019
 

This unique case-based review of surgical oncology offers excellent preparation for oral board examinations, which emphasize both general knowledge and case management. The book presents 91 cases structured to reflect the surgeon’s decision-making process. Each case begins with a patient presentation and imaging studies or pathology results and proceeds through a series of decision points—differential diagnosis, requests for additional tests, diagnosis, surgical approach, discussion of potential pitfalls, and follow-up. Cases are grouped by organ system and each section ends with a treatment algorithm summarizing the decision points. Nearly 400 radiologic images and other relevant illustrations accompany the text.

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Breast Cancer: A New Era in Management

 Oncology  Comments Off on Breast Cancer: A New Era in Management
Oct 142019
 

Breast Cancer: A New Era in Management provides a compendium of succinct analysis of the many facets involved in the present day management of the breast cancer patient. The text provides the clinician or student with basic foundational knowledge in the rapidly expanding areas of expertise that are required for both the diagnosis and treatment of the breast cancer patient. Each topic, whether diagnostic or therapeutic, is presented in a straightforward fashion incorporating as part of each topic a description of the historical clinical landmarks leading to the present day, their present day position in the care of the breast patient, and finally, an assessment of possible future application and adaptation in clinical practice. Emphasis is placed on clear and concise explanations of each topic presented in stepwise fashion from fundamental elements to the more complex.
Breast Cancer: A New Era in Management will act as a ready reference for the practicing surgeon and students seeking practical information on a particular clinical topic or scenario.

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Management of Castration Resistant Prostate Cancer

 Oncology  Comments Off on Management of Castration Resistant Prostate Cancer
Oct 132019
 

This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in depth review of proven therapeutic options, including bone targeted therapies, immunotherapy, chemotherapy and hormonal based therapies. Combination therapy as well as novel targeted approaches presently under investigations are also reviewed. The text provides up to date guidelines and algorithms for the management of CRPC based on international guidelines presently available as well as evidence based medicine.
As a concise yet comprehensive summary of the current status of the field, Management of Castration Resistant Prostate Cancer serves as a very useful resource for physicians and researchers dealing with this challenging malignancy.

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Viruses and Human Cancer

 Oncology  Comments Off on Viruses and Human Cancer
Oct 132019
 

Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis. Chapters are written by internationally recognized experts and all are generously illustrated with tables, diagrams and photographic images.
Viruses and Human Cancer is designed to serve as a concise review of the field of human tumor virology for pathologists, oncologists and infectious disease specialists. It will also be of great value to practicing physicians, residents and clinical fellows in these specialties.

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Orthopaedic Oncology: Primary and Metastatic Tumors of the Skeletal System

 Oncology, Orthopedics  Comments Off on Orthopaedic Oncology: Primary and Metastatic Tumors of the Skeletal System
Oct 102019
 


This text provides a comprehensive overview of orthopaedic oncology – the field of orthopaedic surgery that specializes in the evaluation and treatment of bone and soft tissue tumors of the musculoskeletal system.

The opening chapters cover musculoskeletal imaging interpretation and the principles of musculoskeletal biopsy. Assessment and treatment of the full range of tumors are then described in a series of well-illustrated chapters. Detailed consideration is given to benign tumors, osteosarcomas, Ewing sarcomas, chondrosarcomas, metastatic bone disease of the axial and appendicular skeleton, and soft tissue sarcomas. This book will be invaluable for both orthopaedic surgeons and medical oncologists, providing a framework for understanding the fundamentals of these tumors and a sound basis for their treatment.

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Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics

 Oncology  Comments Off on Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics
Oct 082019
 

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
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Chemo Fog: Cancer Chemotherapy-Related Cognitive Impairment

 Oncology  Comments Off on Chemo Fog: Cancer Chemotherapy-Related Cognitive Impairment
Oct 082019
 

Cancer patients have benefitted greatly from recent advances in the drugs, dose regimens, and combinations used to treat their primary tumor and for the treatment or prevention of spread of their disease. Due to the advances in chemotherapy and other aspects of prevention, early detection, and treatment modalities, an increasing percentage of patients are surviving the disease. For some types of cancer, the majority of patients live decades beyond their diagnosis. For this they are forever thankful and appreciative of the drugs that helped lead to this increased survival rate. But no drug is devoid of adverse effects. This also applies to chemotherapeutic agents. The acute cytotoxic effects of these agents are well known––indeed are often required for their therapeutic benefit. The chronic adverse effects are varied and in some cases less well known. With the increase in survival rates, there has emerged a new awareness of these chronic adverse effects.
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Cancer of the Testis

 Oncology  Comments Off on Cancer of the Testis
Oct 082019
 

The book covers the complete field of testis cancer including the germ cell tumors and the stromal tumors, from epidemiology to new chemotherapeutic agents and schedules, throughout genetic features, risk factors, risk adapted treatments, role of different types of surgery and special clinical situations. Special attention is focused on fertility issues, late effects of the primary therapy and the economical aspects of the different treatment policies.
As a result of the third Consensus Conference, a consensual follow-up can be devised and a chapter dedicated to this controversial and not yet defined matter.
This book is the state-of-the-art reference text on testis cancer and is an essential resource for all urologists, medical oncologists and radio-oncologists.
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Advances in Radiation Oncology in Lung Cancer Edition 2

 Oncology  Comments Off on Advances in Radiation Oncology in Lung Cancer Edition 2
Oct 082019
 

This is the second, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings. The first three sections cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including IMRT, IMAT, cyber knife treatment, and tomotherapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer.
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Hematopoietic Growth Factors in Oncology

 Oncology  Comments Off on Hematopoietic Growth Factors in Oncology
Oct 082019
 

Progress in the treatment of cancer over the past two decades has been rapid with many new and novel therapeutic modalities arriving at an unprecedented pace. Overall cancer mortality rates have actually begun to fall in parallel with progress in the diagnosis and treatment of malignant disease. Despite our advances in the understanding of the biology and molecular genetics of cancer, as well as the availability of an increasing array of effective therapies, cancer treatment today and for the foreseeable future will include the traditional modalities of surgery, radiation therapy and chemotherapy. Myelosuppressive agents with their potential hematopoietic toxicities remain the mainstay of systemic treatment for both metastatic and early stage cancer. The complications of cancer chemotherapy have serious impact on a patient’s well being and overall quality of life. Fortunately, advances in cancer treatment have been accompanied by equally impressive progress in the availability of a wide array of supportive care modalities which have greatly enhanced the ability of oncologists to minimize the impact of cancer and its treatment on patient quality of life as well improve delivery of potentially curative cancer treatment.

Despite the increasing complexity of modern cancer treatment, it is the obligation of the oncologist as well as the entire cancer care team to be certain that cancer patients receive the optimal supportive care available for their disease and its treatment. Among the most serious and potentially life threatening toxicities of cancer treatment are the hematologic toxicities accompanying myelosuppression including anemia and associated asthenia and fatigue, neutropenia and fever associated with infection in the immunocompromised patient and thrombocytopenia and accompanying risk of bleeding. Special supportive care needs arise in the very elderly care patient that may tax the ability of even the most skilled clinician. Despite the considerable progress that has been made with more effective and safer treatment strategies, myelosuppressive chemotherapy will remain the mainstay of systemic treatment for cancer for the foreseeable future. While considerable progress has occurred, better methods and broader application of supportive care measures are needed to reduce the symptomatic effects of cancer and the associated toxicities associated with cancer treatment.
No area of cancer supportive care better illustrates the progress that has resulted from advances in our understanding of cellular and molecular biology, genetic engineering and the development of more effective yet often more toxic cancer treatments than that of the hematopoietic growth factors. This volume will review and integrate the major advances in our understanding of the underlying molecular biology and pharmacology of these agents along with the results of well designed and executed randomized controlled trials of the erythroid stimulating agents, the myeloid growth factors and the new thrombopoietic agents each addressing a major threat associated with bone marrow suppression accompanying cancer treatment. The current clinical utilization of these agents is based on numerous randomized controlled trials and meta-analyses along with evidence-based clinical practice guidelines developed by professional societies guiding their appropriate and cost-effective use in clinical care.

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