Cancer and Society: A Multidisciplinary Assessment and Strategies for Action

 Oncology  Comments Off on Cancer and Society: A Multidisciplinary Assessment and Strategies for Action
Mar 242019
 

While a number of books have looked at the intersection between human health in general and other topics, such as climate change or diet, this book focuses specifically on cancer as it impacts and is impacted by social justice issues. The massive explosion of research knowledge of cancer immunology and genomics is holding out great promise of therapeutic advances, yet other human actions―climate change, pollution, business decisions, advertising – are fostering health inequalities as well as increasing risks. Those involved in cancer care and research are in a unique position to let their experiences and knowledge inform the public, yet very often have not taken strong public roles when it comes to discussing issues surrounding tobacco, climate change and health risks, financial toxicity of treatments, and diet choices.

Written by a multidisciplinary team of authors and for medical oncologists, cancer researchers, occupational health workers, and related medical students, residents, and fellows, this book encourages oncologists to address public health care and the societal issues associated with cancer risk. This volume discusses the overarching theme of environmental justice and oncology, focuses on business and cancer (such as clinical trials, drug development and profits, and global disparities), as well as animals and cancer.

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Handbook of Cancer Survivorship Care

 Oncology  Comments Off on Handbook of Cancer Survivorship Care
Mar 192019
 

Handbook of Cancer Survivorship Care serves as a practical and concise guide for the multidisciplinary management of cancer survivors. Nearly all of the chapters are authored by a team consisting of a seasoned oncologist and an experienced practitioner who provides direct services in survivorship care. Chapters reflect the importance of interdisciplinary collaboration and cover the high-yield pearls and clinical applications that lead to quality patient care outcomes. Part I discusses the basic concepts of survivorship care, models of care, and clinical tools while addressing late and long-term effects of treatment, screening methods for secondary or recurring tumors, and prevention of disease relapse. Part II includes chapters on cancers commonly seen in community practice, such as breast, prostate, lymphoma, and colorectal. Chapters in Part II provide clinical pearls and disease-specific background, a guide to disease surveillance, instructions for monitoring late effects, early detection tips, and information on psychosocial health, all to better direct clinical assessment and management. With cancer survivors an increasing segment of the healthcare population and survivorship care rapidly evolving, it is paramount that oncologists and other care providers are up-to-date on the clinical strategies, interventions, and recommendations for follow-up care. As a pocket-sized, quick reference, Handbook of Cancer Survivorship Care is an indispensable resource for any healthcare provider – including physicians, nurses, and other practitioners – seeing patients in remission; it covers the must-know points of clinical management and successfully carries over cutting-edge expertise into clinical practice whether it is used at the bedside or in the clinic.

Key Features:

Includes practical guidance on challenging areas such as addressing psychosocial issues, establishing screening and prevention strategies, managing late effects in cancer survivors and many more
Easy-to-read outline format makes referencing in the clinical setting quick and convenient
Practical clinical vignettes with self-assessment Q&A accompany chapters in Part II
Clinical pearls highlight survivorship guidelines and their application
Provides management guidelines and detailed disease surveillance strategies for site-specific cancers
Includes digital access to the e-book

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Reading and Writing Cancer: How Words Heal

 Oncology  Comments Off on Reading and Writing Cancer: How Words Heal
Mar 192019
 

An important addition to the literature of cancer by an award-winning scholar and memoirist.

Elaborating upon her “Living with Cancer” column in the New York Times, Susan Gubar helps patients, caregivers, and the specialists who seek to serve them. In a book both enlightening and practical, she describes how the activities of reading and writing can right some of cancer’s wrongs. To stimulate the writing process, she proposes specific exercises, prompts, and models. In discussions of the diary of Fanny Burney, the stories of Leo Tolstoy and Alice Munro, numerous memoirs, novels, paintings, photographs, and blogs, Gubar shows how readers can learn from art that deepens our comprehension of what it means to live or die with the disease.

From a writer whose own memoir, Memoir of a Debulked Woman: Enduring Ovarian Cancer, was described by the New York Times Book Review as “moving and instructive…and incredibly brave,” this volume opens a path to healing.

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After You Hear It’s Cancer: A Guide to Navigating the Difficult Journey Ahead

 Oncology  Comments Off on After You Hear It’s Cancer: A Guide to Navigating the Difficult Journey Ahead
Mar 182019
 

In 2014, an estimated 1.66 million people will receive a diagnosis of cancer. They will join a pool of 13.7 million Americans already living with a history of cancer. Almost 600,000 Americans will die from cancer. For some, cancer will be only a short divergence. For others, however, it will be a dramatic fork in the road. And for still others, the beginning of the end of the line.

This book guides cancer patients along their journey where no one knows the duration or the destination. Divided into the three parts of being a cancer patient—the diagnosis, initial treatment, and on to survivorship—the book will help the newly diagnosed cancer patient navigate a complex health care system, make astute decisions at difficult junctures, and manage the emotional turbulence that can rock his or her world. Lastly, it shares the story of how the author and his wife, as well as other cancer patients, have confronted their disease.

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Clinical Ophthalmic Oncology: Retinal Tumors, 3rd edition

 Oncology  Comments Off on Clinical Ophthalmic Oncology: Retinal Tumors, 3rd edition
Mar 182019
 

Written by internationally renowned experts, the 3rd edition of this six volume textbook provides detailed practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. Supplying the reader with state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible, this book is divided into six volumes: Basic Principles, Eyelid and Conjunctival Tumors, Orbital Tumors, Uveal Tumors, Retinal Tumors, and Retinoblastoma. The information presented enables readers to provide effective patient care using the latest knowledge on ophthalmic oncology and to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs from the authors’ private collections, histopathologic microphotographs, imaging studies, and crisp illustrations.

Clinical Ophthalmic Oncology’s clinically focused and user-friendly format allows for rapid retrieval of information in daily practice and is written for residents, fellows, and any physician involved in the care of patients with ocular or orbital malignancies. Additionally, this edition adds several hundred new images to improve comprehension of procedures and techniques. This volume provides diagnosis and therapy for retinal tumors, including vitreoretinal lymphoma and paraneoplastic disorders.

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Computational Cancer Biology: An Interaction Network Approach

 Oncology  Comments Off on Computational Cancer Biology: An Interaction Network Approach
Mar 162019
 

This brief introduces people with a basic background in probability theory to various problems in cancer biology that are amenable to analysis using methods of probability theory and statistics. The title mentions “cancer biology” and the specific illustrative applications reference cancer data but the methods themselves are more broadly applicable to all aspects of computational biology. Aside from providing a self-contained introduction to basic biology and to cancer, the brief describes four specific problems in cancer biology that are amenable to the application of probability-based methods. The application of these methods is illustrated by applying each of them to actual data from the biology literature. After reading the brief, engineers and mathematicians should be able to collaborate fruitfully with their biologist colleagues on a wide variety of problems.
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Triple-Negative Breast Cancer : Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges

 Oncology  Comments Off on Triple-Negative Breast Cancer : Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges
Mar 152019
 

Poorly differentiated triple negative breast cancers (TNBCs) were first characterized in the literature in 2005 by the absence of receptors for estrogen (ER) and progesterone (PR) as well as the lack of tyrosine kinase human epidermal growth factor receptor 2 (HER-2). Clinically, TNBCs exhibit fairly aggressive local growth, rapid progression and account for a high rate of early metastases, most commonly to visceral organs and central nervous system. Chapter One describes how the last decade has contributed to the authors’ understanding of the function of exosomes in the progression of breast cancer. Furthermore, it will discuss the implications for using exosomes from body fluids as biomarkers in diagnosis and treatment strategies. Chapter Two discusses how the strong correlation between BRCA gene mutations and the high risk of TNBC proposes certain mediators between germline mutations and the risk for poorly differentiated breast cancers. Chapter Two presents increasing evidence of the role of tumor lymphocytic immune infiltrates in this subtype of breast cancer. High levels of tumor infiltrating lymphocytes (TILs), mainly in lymphocyte-predominant breast cancer (LPBC), have been associated with improved disease-free and overall survival rates in TNBC patients with and without any treatment.

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Thyroid Nodules and Cancer : A Simplified Case Oriented Approach, Enhanced Edition

 Oncology  Comments Off on Thyroid Nodules and Cancer : A Simplified Case Oriented Approach, Enhanced Edition
Mar 152019
 

This practical guide to the management of thyroid nodules and cancer offers the practitioner a common-sense approach to the management of an increasingly common clinical problem. Thyroid cancer is the most rapidly increasing cancer diagnosis in the United States and is now the fifth most common cancer among women. Indeed, an estimated 65,000 adults (15,000 men and 50,000 women) in the United States will be diagnosed this year with thyroid cancer. Many more will be treated for thyroid nodules. Unfortunately, practice patterns still vary greatly across the country and the world. Many patients the authors believe are inappropriately treated. Practitioners seeking to help their patients and make sense of conflicting thyroid cancer guidelines will discover illustrative cases that represent common situations in clinical practice. Unlike encyclopedic guidelines and impenetrable textbooks, this straightforward casebook engages, informs and entertains the reader. Even so, the book’s scenarios cover a broad range of clinical presentations from incidental microcarcinomas to invasive metastatic cancers. Here, molecular diagnostics and advanced imaging are demystified and incorporated into common-sense approaches stressing the importance of personalized care. And readers seeking deeper understanding will be guided in the book’s digital version with hyperlinks to primary source material.

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An Introduction to Microwave Imaging for Breast Cancer Detection (Biological and Medical Physics, Biomedical Engineering)

 Oncology, Radiology  Comments Off on An Introduction to Microwave Imaging for Breast Cancer Detection (Biological and Medical Physics, Biomedical Engineering)
Mar 092019
 

This book collates past and current research on one of the most promising emerging modalities for breast cancer detection. Readers will discover how, as a standalone technology or in conjunction with another modality, microwave imaging has the potential to provide reliable, safe and comfortable breast exams at low cost. Current breast imaging modalities include X- ray, Ultrasound, Magnetic Resonance Imaging, and Positron Emission Tomography. Each of these methods suffers from limitations, including poor sensitivity or specificity, high cost, patient discomfort, and exposure to potentially harmful ionising radiation. Microwave breast imaging is based on a contrast in the dielectric properties of breast tissue that exists at microwave frequencies.

The book begins by considering the anatomy and dielectric properties of the breast, contrasting historical and recent studies. Next, radar-based breast imaging algorithms are discussed, encompassing both early-stage artefact removal, and data independent and adaptive beamforming algorithms. In a similar fashion, microwave tomographic reconstruction algorithms are reviewed in the following chapter, introducing the reader to both the fundamental and more advanced algorithms. Apart from imaging, the book also reviews research efforts in extracting clinically useful information from the Radar Target Signature of breast tumours, which is used to classify tumours as either benign or malignant. Finally, the book concludes by describing the current state of the art in terms of prototype microwave breast imaging systems, with a particular emphasis on those which have progressed to the clinical evaluation stage.
This work is motivated by the fact that breast cancer is one of the leading causes of death amongst women in Europe and the US, and the second most common cancer in the world today. Such an important area of research will appeal to many scholars and practitioners.p>

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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer – Illumination of a Vision

 Oncology  Comments Off on Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer – Illumination of a Vision
Mar 092019
 

This Special Issue has been introduced with the aim of offering the possibility to publish new research results from old and new pioneers in the field of bladder cancer basic research. While editing this Special Issue we learned that an enormous enthusiasm is necessary to go on in bladder cancer research.
In our eyes, bladder cancer is on one hand a very heterogenous malignancy, which is what makes it so difficult to focus on only one bladder cancer marker in bladder cancer diagnostics and follow-up. On the other hand, it is very important to find prognostic and predictive factors for bladder cancer due to its high incidence and its enormous costs, as one of the most expensive malignancies in the world. Finding and developing new bladder cancer markers is still a very dynamic field. Because there are many of these markers, it is impossible to report all of them. This Special Issue attempts to highlight the role of bladder cancer markers in diagnosis, and the most important biomarkers that have been recently studied and reported. This Special Issue highlights some of the most important markers. Further determination of recurrence and progression markers will contribute to establishing better treatments for individual patients. Molecular staging of urological tumors will allow the selection of cases that will require systemic treatment. It is necessary and important to integrate basic and clinical research under the same objectives.

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