Kidney Cancer: Recent Advances in Surgical and Molecular Pathology

 Oncology, Pathology, Surgery  Comments Off on Kidney Cancer: Recent Advances in Surgical and Molecular Pathology
Dec 112019
 

This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification.
Written by experts in the field, chapters contain an updated review of important pathologic parameters mandated for diagnosis and reporting with emphasis on updated information regarding new developments in this interesting field. Numerous high-resolution color images aptly illustrate the various pathologic entities and their features as outlined in the text section along with tables that highlight the differential diagnoses and salient ancillary features.
Kidney Cancer serves as a quick reference for all categories of readers alike, and provides up-to-date information on renal tumor pathology, radiology and management that are required in daily practice.

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Ethical Issues in Pediatric Hematology/Oncology

 Hematology, Oncology, Pediatrics  Comments Off on Ethical Issues in Pediatric Hematology/Oncology
Dec 112019
 

This book identifies the various ethical challenges that arise in pediatric hematology/oncology and provides the necessary tools to overcome these challenges. Aiming to expand upon and strengthen providers’ knowledge and experience in pediatric health care ethical issues, the text positions providers to be beneficial resources to faculty, staff, patients, and families within their institution.
It presents a multidisciplinary approach to sound ethical practices that is necessary to effectively care for these patients and their families. The book reviews the principles of ethical decision-making, the unique difficulties in using children as research subjects, common ethical conundrums involved in providing end-of-life care, and general moralities of professional practice.
Written by experts in their fields, Ethical Issues in Pediatric Hematology/Oncology is an innovative and valuable resource for clinicians, practitioners, and trainees who work in the field of pediatric hematology/oncology.

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Molecular Pathology of Gynecologic Cancer

 Ob/Gynae, Oncology, Pathology  Comments Off on Molecular Pathology of Gynecologic Cancer
Dec 102019
 

This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.
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Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future

 Oncology  Comments Off on Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future
Dec 102019
 

Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multi-modality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology.
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Treatment and Management of Cancer in the Elderly (Basic and Clinical Oncology)

 Oncology  Comments Off on Treatment and Management of Cancer in the Elderly (Basic and Clinical Oncology)
Dec 092019
 

Building upon the strengths of the popular reference, Cancer in the Elderly, this guide outlines novel approaches in the identification and management of cancer in geriatric populations by world-renowned experts on the topic. Presenting new trends and strategies in surgery, radiation therapy, and chemotherapy, this source presents a multidisciplinary and best-practices approach to the optimization of cancer care for the elderly and collects the most recent findings gleaned from prevention, adjuvant, neo-adjuvant, and treatment research.
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Signaling Pathways in Cancer Pathogenesis and Therapy

 Oncology  Comments Off on Signaling Pathways in Cancer Pathogenesis and Therapy
Dec 082019
 

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.
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Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

 Oncology  Comments Off on Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach
Dec 072019
 

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

 Oncology  Comments Off on Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics
Dec 072019
 

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.

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Skin Aging & Cancer: Ambient UV-R Exposure

 Dermatology, Oncology  Comments Off on Skin Aging & Cancer: Ambient UV-R Exposure
Dec 072019
 

This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation. Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body. This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer. The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells. It also elucidates the potential of nanotechnology in the treatment of skin cancer. Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.

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Advancing the Science of Cancer in Latinos

 Oncology  Comments Off on Advancing the Science of Cancer in Latinos
Dec 072019
 

This book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio.
Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress.

The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos.

Topics included among the chapters:

Colorectal cancer disparities in Latinos: Genes vs. Environment
Breast cancer risk and mortality in women of Latin American origin
Differential cancer risk in Latinos: The role of diet
Overcoming barriers for Latinos on cancer clinical trials
Es tiempo: Engaging Latinas in cervical cancer research
Emerging policies in U.S. health care
Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

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