Cytokines in the Treatment of Infectious Diseases: Options for the Modulation of Host Defense

 Infectious Diseases  Comments Off on Cytokines in the Treatment of Infectious Diseases: Options for the Modulation of Host Defense
Jan 182019
 

Only recently a new range of agents has become available that are capable of stimulating and regulating host defense systems against microorganisms. Interleukins, interferons and haematopoietic growth factors are now being produced by the biotechnology industry and are being evaluated for clinical use in this area. Cytokines in the Treatment of Infectious Diseases provides a unique, up-to-date survey of this research area. The use of cytokines in a series of (groups of) infectious diseases is discussed in twelve succinct chapters, from model to clinical study, written by twenty-five expert authors from the world’s key institutes in this area. The book is aimed at microbiologists, immunologists, molecular biologists, cell biologists and other scientific disciplines in the field of biotherapy. It is required reading for physicians dealing with infectious diseases who wish to keep up to date with the developments in this field.
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The Imaging of Infection and Inflammation

 Infectious Diseases, Radiology  Comments Off on The Imaging of Infection and Inflammation
Jan 152019
 

Despite 50 years of antibiotics, infection remains a major source of both morbidity and mortality. Immunosuppression, either secondary to drugs in transplant recipients or secondary to HIV, has expanded the number of microorganisms that are known to be pathogenic in man. Imaging of infection has a vital role both in the initial diagnosis and in the continuing management of patients with infection or suspected infection. Functional imaging using nuclear medicine techniques has a unique role to play in identifying sites of infection in a wide range of patients with varying clinical conditions. This book, written by a series of experts not just in the fields of nuclear medicine but also infectious disease and radiology, discusses the role of nuclear medicine in three parts: a review of the pathophysiology of infection; a technical description of those nuclear medicine techniques which can be used in imaging infection; an extensive systematic review including thoracic, abdominal and orthopaedic infection as well as a special section on the acutely ill patient, the immunosuppressed patient and the patient with pyrexia of unknown origin. This book will be of interest to all clinicians looking after patients with infection and who need to use imaging techniques. It will also be of use to radiologists and nuclear medicine physicians who will be using these techniques clinically.
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Infectious Complications of Cancer

 Infectious Diseases, Oncology  Comments Off on Infectious Complications of Cancer
Jan 132019
 

Despite the major developments in the therapeutic armamentarium for the treatment of infection, the morbidity and mortality of this complication remains very high in patients with compromised defences. Cancer and its treatment represents a major predisposing condition to a variety of infections. These adverse events are still with us, in spite of much progress in the therapy of infectious disease, since cancer therapy is becoming more aggressive, yet further lowering the host’s capacity to cope with infections. Moreover, the pathogens adapt effectively to drugs, and at a pace that might outrun industry’s capability to produce new agents. Finally, new pathogens are appearing as a consequence of both selection and severe immunosuppression. Infection is so common among cancer patients that its diagnosis and management represent a daily challenge to all oncologists, who must continually strive to keep abreast of developments in the area. The present comprehensive review of the most crucial and challenging aspects of the infectious complications in cancer patients will help them to do just that.
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Immunopathogenesis of HIV Infection

 Immunology, Infectious Diseases, Pathology  Comments Off on Immunopathogenesis of HIV Infection
Jan 022019
 

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies. These oberservations include: 1. The delineation of the virologic and immunologic events associated with primary HIV infection. 2. The development of highly sensitive molecular techniques including polymerase chain reaction (PCR) assays for the determination of HIV RNA in plasma, together with the identification of lymphoid tissue as the primary anatomic site for HIV replication and spreading. 3. The characterization of the dynamics of HIV infection. 4. The identification of chemokines with suppressor activity on HIV replication and the discovery of co-receptor molecules for HIV entry.
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Epidemic of Medical Errors and Hospital-Acquired Infections: Systemic and Social Causes

 Epidemiology, Infectious Diseases  Comments Off on Epidemic of Medical Errors and Hospital-Acquired Infections: Systemic and Social Causes
Dec 132018
 


Medical error as defined in Epidemic of Medical Errors and Hospital-Acquired Infections: Systemic and Social Causes encompasses many categories including, but not limited to, medical error, hospital-acquired infections, medication errors, deaths from misdiagnosis, deaths from infectious diarrhea in nursing homes, surgical and post-operative complications, lethal blood clots in veins, and excessive radiation from CT scans.

When the deaths from these categories are counted they become the leading cause of fatality to Americans, outpacing cancer and heart disease. Add the numbers of fatalities (mortality) to the millions each year who are injured (morbidity) and whose quality of life is forever effected, and an epidemic of harm is defined.

The book describes the many systemic and social causes of medical error and iatrogenic events, all of which are cited in the peer-review science, that have a direct effect on the epidemic of patient injury, but are rarely or never considered. These systemic causes include factory medicine (for-profit medicine), staffing ratios in clinical and non-clinical departments, shift work, healthcare working conditions, lack of accountability, legal issues that conflict with patient safety issues, bullying and hierarchical relationships, training of healthcare workers that never rises to the level of risk, and injury to healthcare workers. The premise of the book is that if the systemic or social causes are not considered or changed, then medical error will continue to be an epidemic and no substantial impact in the numbers will be realized.

An expert with 30 years of experience as a health and safety officer in healthcare and as an activist for community health and safety issues, editor and author William Charney explores the issues surrounding medical errors and examines the science behind possible solutions. He presents an efficient dialogue that produces a more systemic exploration and targeting of the causes of medical error and drives an exacting message: we are dealing with an epidemic of harm, and unless systemic issues are solved, little will change to subdue the epidemic.

Information on the June 2012 Conference on the Epidemic of Medical Errors & Hospital Acquired Infections in the US and Canada: the Systemic Causes can be found on the CRC Press Issuu page.

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Advances in Microbiology, Infectious Diseases and Public Health: Volume 9

 Infectious Diseases, Microbiology  Comments Off on Advances in Microbiology, Infectious Diseases and Public Health: Volume 9
Nov 082018
 

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention.
Advances in Microbiology, Infectious Diseases and Public Health is a subseries of Advances in Experimental Medicine and Biology, which has been publishing significant contributions in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. 2016 Impact Factor: 1.881.

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Infectious Diseases in Pediatric Otolaryngology: A Practical Guide

 Infectious Diseases, Pediatrics  Comments Off on Infectious Diseases in Pediatric Otolaryngology: A Practical Guide
Oct 252018
 

​This quick reference on pediatric infectious diseases of the ear, nose, and throat provides reliable assistance in decision-making and management. To this end, numerous diagnostic and treatment algorithms are included. Practicing pediatricians, primary care practitioners, and otolaryngologists will all find the book to be an invaluable aid.

This book helps the otolaryngologist who is uncertain of the best antibiotic or duration of treatment for a particular condition and instructs the pediatrician on when to refer to an otolaryngologist for surgical management. The approach is multidisciplinary, with contributions from both pediatric otolaryngologists and pediatric infectious disease physicians.

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Manual of infection prevention and control

 Infectious Diseases  Comments Off on Manual of infection prevention and control
Oct 242018
 

It has been estimated that in developed countries up to 10% of hospitalized patients develop infections every year. Not only is there a substantial cost to healthcare systems, but some healthcare associated infections (HCIAs) can be fatal. Since the majority of HCIAs are preventable, reducing HCIAs is now considered to be an integral part of patient safety and quality of care provided by all healthcare institutions worldwide.Unlike other books on infection control, the main strength of this book is to provide clear, up-to-date and practical guidance in infection control in an easy to read format which can act as a quick source of reference on all aspects of HCIA for healthcare workers who are either directly or indirectly involved in prevention and control of HCIAs. Although the book’s main audience is infection control practitioners such as doctors, nurses, public health physicians, it is also a valuable reference for environmental health officers, health educators, practice managers in GP surgeries, and health service managers.
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All About Pandemics (Epidemic of Infectious Disease)

 Epidemiology, Infectious Diseases  Comments Off on All About Pandemics (Epidemic of Infectious Disease)
Oct 052018
 


This is a Complete Book to Know All About Pandemics (Epidemic of Infectious Disease).

Table of Contents

Chapter 1 – Introduction to Pandemic
Chapter 2 – 2009 Flu Pandemic
Chapter 3 – AIDS Pandemic
Chapter 4 – Cholera Pandemics
Chapter 5 – Influenza Pandemic
Chapter 6 – Third Pandemic
Chapter 7 – Viral Hemorrhagic Fever & Antibiotic Resistance

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Oxford Handbook of Infectious Diseases and Microbiology

 Infectious Diseases, Microbiology  Comments Off on Oxford Handbook of Infectious Diseases and Microbiology
Sep 282018
 

 

Fully reviewed and revised for its second edition, the Oxford Handbook of Infectious Diseases and Microbiology maintains its position as the must-have guide to all aspects of infectious diseases and microbiology. Reflecting the current approach to joint postgraduate training programmes, the handbook takes an integrated approach to both subjects. It covers the basic principles of bacteriology and virology, along with specific guidance on individual diseases and conditions, all in the accessible Oxford Handbook style. Now including new topics on important subjects such as microbiology specimen collection, commonly used media, molecular diagnostics, and antimicrobials in pregnancy, as well as incorporating new guidelines from WHO, NICE, and BASHH among others, this handbook ensures that the informaiton you need is accessible, clear, and easy-to-understand.Practical and comprehensive, this handbook includes coverage of National Frameworks and current legislation, together with information on topical issues such as bioterrorism and preventative medicine. Fully reviewed by specialist senior readers, and with useful links to up-to-date clinical information and online resources, this is an important addition to the Oxford Handbook Series.
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