Feb 102017
 

2014 Nelson’s Pediatric Antimicrobial Therapy


By (author): John S. Bradley MD, John D. Nelson MD Emeritus

New 20th Edition!  This bestselling and widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of all infectious diseases in children.  

For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices.  Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. In response to growing concerns about overuse of antibiotics, the program includes guidelines on when not to prescribe antimicrobials.

Practical, evidence-based recommendations from the experts in antimicrobial therapy:

  • Developed by distinguished editorial board

  • Designed for those who take care of children and are faced with decisions every day

  • Includes treatment of parasitic infections and tropical medicine.

  • Updated assessments regarding the strength of the recommendation and the level of evidence for treatment recommendations for major infections

  • Anti-infective drug listing, complete with formulations and dosages

  • Antibiotic therapy for obese children

  • Antimicrobial prophylaxis/prevention of symptomatic infection

  • Maximal adult dosages and higher dosages of some antimicrobials commonly used in children

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Jan 262017
 

The CAPRISA Clinical Trials: HIV Treatment and Prevention


Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA’s high impact studies was created, developed, implemented, analysed and communicated.  In doing so, the reader is taken on a journey that provides glimpses into the genesis of research ideas and how this ultimately leads to a range of HIV prevention and treatment studies that have impacted the global response to the HIV and TB epidemics.

Comprised of 5 sections, the book details the following:

  1. HIV epidemic in South Africa and the establishment of a research centre to undertake clinical, epidemiological and laboratory research on HIV.
  2. CAPRISA’s clinical trials on HIV and HSV-2 prevention. These studies investigated the impact of tenofovir gel as topical antiretroviral pre-exposure prophylaxis (PrEP), implementation of topical PrEP through family planning clinics, conditional cash incentives for HIV prevention, HIV vaccines, and passive immunisation with broadly neutralising antibodies.
  3. CAPRISA’s research on the treatment of HIV and TB co-infection.
  4. A review of the major scientific findings from the CAPRISA studies on acute infection and genital mucosal immunology. 
  5. Essential support activities for the conduct of clinical trials, including research laboratories and pharmacies, as well as establishing effective communication and sustainable structures for community engagement to maintain effective and respectful partnerships with participating communities. The book concludes with a chapter about the challenges facing future HIV prevention and treatment trials.

The CAPRISA Clinical Trials: HIV Treatment and Prevention is a resource for undergraduate and postgraduate students, health care providers, doctors, decision-makers and researchers who are seeking guidance and insights on clinical trials – their creation, conduct and impact.

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Jan 182017
 

Essentials of Clinical Infectious Diseases


Features: Used Book in Good Condition

This practical handbook provides readers with a quick but comprehensive overview of the major infectious disease topics and clinical approach to diagnosis and management. Covering the core areas of importance to students, residents, fellows, and practitioners in any discipline, the book presents a systematic method for understanding basic mechanisms, establishing a diagnosis, and implementing appropriate treatment for commonly encountered problems. Written in outline format with 46 short, focused chapters, this ready reference is essential reading for physicians looking for guidance in navigating the constellation of symptoms and myriad treatment options for patients with infectious diseases.

Organized by body system, each section begins with a general framework covering clinical presentation, laboratory and diagnostic evaluation, and empirical antibiotic therapy. Individual chapters within sections are devoted to particular diseases and cover pathogenesis and risk factors, microbial causes, clinical manifestations, approach to the patient (history, examination, and diagnostic studies), diagnostic criteria, and medical, antimicrobial, and surgical management. Essentials of Clinical Infectious Diseases also addresses important related topics including antimicrobial agents, medical microbiology, fever and neutropenia, approach to evaluating leukocytosis, infectious diseases approach to SIRS and sepsis, and basics of infection control and hospital epidemiology. With this book, readers will have at hand the fundamental knowledge necessary to sharpen the clinical problem-solving skills that every medical professional needs to provide quality care to patients.

Features of Essentials of Clinical Infectious Diseases include:

  • A detailed discussion of core infectious disease topics
  • Antibiotic information specific to the disease process with adult, pediatric, and OB-GYN dosing considerations
  • Basic infection control procedures for hospitalized patients
  • Coverage of important related topics
  • References to current literature and classic articles for further study
  • A focus on clinical approaches to evaluation and management of the patient

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Jan 172017
 

Epstein Barr Virus: Methods and Protocols (Methods in Molecular Biology)


This volume explores data from the applications of molecular biological methods and the applications of recent immunological and cytogenetic methods in Epstein-Barr Virus (EBV) that will offer readers possible new solutions to the unresolved problems in the EBV field. Chapters in this book cover topics such as: viral life cycle, latency, EBV-associated diseases and EBV diagnostics; in vitro methods including organotypic cultures for the analysis of EBV-epithelial cell interactions; identification of the interacting viral and cellular proteins using affinity purification-mass spectrometry methods; 3D telomere FISH; transcription analysis using high-throughput RNA sequencing, qPCR and nuclear run-on assay; analysis of viral and cellular microRNAs; isolation and characterization of exosomes and the assessment of their function; characterization of the viral genome by terminal repeat analysis and sequencing; the use of chromatin immunoprecipitation coupled sequencing (ChIP-Seq) for the analysis of Zta-DNA interactions; epigenetic analysis by bisulfite sequencing and ChIP; novel in vivo models for the study of EBV infection; and how immunological, virological, tissue culture and molecular methods can be combined to yield Good Manufacturing Practice-compliant EBV-specific T cells for the immunotherapy of EBV-associated post-transplant lymphoproliferative diseases (PTLD). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Epstein Barr-Virus: Methods and Protocols is a valuable resource for anyone who is interested in this fascinating and evolving field.

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Jan 072017
 

Lymphatic Filariasis


By (author): Trilok Chandra Goel, Apul Goel

This book provides up-to-date information on lymphatic filariasis supported with abundant images, tables and algorithms. It is a first such monograph on a disease that has varied presentations which are complete clinical entities, such as chyluria, hydrocele, elephantiasis, etc. 
This book consists of three parts, parasitology, acute clinical manifestations and chronic presentations of the disease. 
Approximately 120 million people are infected with lymphatic filariasis in tropical and subtropical countries. About a third of these suffer clinical consequences of this infection, and many are seriously disfigured. India, Indonesia and Nigeria are the most endemic countries in the world. In spite of Global Control Program of WHO, filariasis continues to be a significant medical challenge and current efforts underway will take a long time to bring it under control. 
Lymphatic Filariasis is meant for general surgeons, physicians, urologists and plastic surgeons, including the postgraduate students. Useful for epidemiologists, internists, and those involved in filariasis prevention programs. 
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Jan 042017
 

Human Emerging and Re-emerging Infections Set


Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology.

Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections.

Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

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Jan 032017
 

Viral Infections and Treatment (Infectious Disease and Therapy)


Features: Used Book in Good Condition

Examining the pathology and transmission of the most common viral diseases, this reference compiles reviews by international specialists which detail breakthroughs in patient management, diagnostics and treatment of viral infections. The text also describes specific therapeutic agents according to their mode of action and clinical applications, as well as practical treatment recommendations and guidelines for improved patient care.

List Price: $230.00 USD
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Jan 022017
 

ABC of HIV and AIDS


Features: Used Book in Good Condition

An authoritative guide to the epidemiology, incidence, testing and diagnosis and management of HIV and AIDS.

From an international expert editor and contributor team, this new sixth edition includes expanded coverage of HIV testing, assessment and routine follow up and new chapters outlining problematic conditions associated with HIV and AIDS. Prevention strategies, early diagnosis and antiretroviral drugs and pharmacotherapy are covered in detail as well as children and women with HIV. It also addresses key psychological and mental health issues, patient perspectives and the role of patient engagement.

 As knowledge into the illness grows and major advances in HIV therapy see more people living with HIV in the community, the ABC of HIV and AIDS, 6e provides clear practical guidance for general practitioners, hospital doctors, nurses, medical students, counsellors, allied health workers and anyone working and caring for patients with HIV and AIDS.

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Dec 312016
 

Role of Apoptosis in Infection (Current Topics in Microbiology and Immunology)


Apoptosis is a regulated, energy-dependent process by which a cell se- destructs. This mechanism of programmed cell death plays an important role in normal development and control of cell numbers in mature a- mals. Apoptosis was initially defined by morphological criteria to describe the distinctive appearance of dying cells that developed nuclear conden- tion, cell shrinkage, and cytoplasmic blebbing. Initiation of the apoptotic process can come from external or internal stimuli and is highly regulated both by molecules that facilitate and by molecules that inhibit the process. Common features of apoptosis include activation of proteases and – cleases, mitochondrial membrane permeabilization, chromatin disruption, and translocation of phosphatidylserine from the inner to the outer s- face of the plasma membrane. Apoptotic cells attract phagocytes that – gulf the apoptotic bodies and prevent tissue damage in the region. Intense investigation of the cell death process has defined many molecular features of the pathway by which regulation and execution can be exploited by pathogens.
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Dec 202016
 

Infection Control for Advanced Practice Professionals


By (author): Denise M. Korniewicz

Presents best practices for infection prevention and control in advanced practice Emphasizes team approach for infection control Case study provided for each chapter

——————————————————————————– This professional reference combines research on the best practices for infection control in clinical settings with essential information for advanced practice nurses and physician assistants. The book is organized by healthcare settings, and the coverage ranges from small practice offices to large hospitals and medical institutions. Each chapter is prefaced by a case study which is then incorporated into the theoretical material of the chapter as a continuing illustration. This format provides a reader-friendly instructional resource for advanced practice certifications and staff development.

From the Foreword

“At last is published a long-needed text for advanced practice nurses (APNs), providing them with the information essential to the care of essentially every patient they will encounter. Infection Control for Advanced Practice Professionals fills a void in the literature and recognizes the importance of a team approach to the prevention of infections in the variety of care settings in which APNs are practicing. The book is particularly timely and relevant because it appropriately places infection prevention solidly within the larger patient safety movement and affirms that preventing infections is everybody’s concern. In acute care settings, for example, infection control has occasionally been relegated to the infection prevention specialist (e.g., infection control nurse or hospital epidemiologist) or the infection control committee. This has shown to be ineffective in any setting. It is those who “touch” the patients and oversee their care who must assume the responsibility for preventing untoward events such as infections. While not all infections are preventable, there is indeed room for improvement. This comprehensive reference is a first and essential step in that direction!”

Elaine Larson, PhD, RN, FAAN, CIC Anna C. Maxwell Professor of Nursing Research Associate Dean for Research School of Nursing Professor of Epidemiology Joseph Mailman School of Public Health Columbia University Editor, American Journal of Infection Control

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