Modeling to Inform Infectious Disease Control

 Infectious Diseases  Comments Off on Modeling to Inform Infectious Disease Control
Mar 242019

Effectively Assess Intervention Options for Controlling Infectious Diseases Our experiences with the human immunodeficiency virus (HIV), severe acute respiratory syndrome (SARS), and Ebola virus disease (EVD) remind us of the continuing need to be vigilant against the emergence of new infectious diseases. Mathematical modeling is increasingly used in the management of infectious disease control as a way to assess interventions relatively quickly, cheaply, and safely. Modeling to Inform Infectious Disease Control shows readers how to take advantage of these models when developing strategies to mitigate infectious disease transmission. The book presents a way of modeling as well as modeling results that help to guide the effective management of infectious disease transmission and outbreak response. It discusses the requirements for preventing epidemics and ways to quantify the impact of preventative public health interventions on the size and dynamics of an epidemic. The book also illustrates how data are used to inform model choice. Accessible to readers with diverse backgrounds, this book explains how to gain insight into the management of infectious diseases through statistical modeling. With end-of-chapter exercises and glossaries of infectious disease terminology and notation, the text is suitable for a graduate-level public health course. Supplementary technical material is provided at the end of each chapter for readers with a stronger background in mathematics and an interest in the art of modeling. In addition, bibliographic notes point readers to literature in which extensions and more general results can be found.



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Urbanization and Slums: Infectious Diseases in the Built Environment

 Infectious Diseases  Comments Off on Urbanization and Slums: Infectious Diseases in the Built Environment
Mar 192019

by Engineering, and Medicine National Academies of Sciences (Author), Health and Medicine Division (Author), Board on Global Health (Author), Forum on Microbial Threats (Author), Anna Nicholson (Editor), Cecilia Mundaca Shah (Editor), V. Ayano Ogawa (Editor)

The urban built environment is a prime setting for microbial transmission, because just as cities serve as hubs for migration and international travel, components of the urban built environment serve as hubs that drive the transmission of infectious disease pathogens. The risk of infectious diseases for many people living in slums is further compounded by their poverty and their surrounding physical and social environment, which is often overcrowded, is prone to physical hazards, and lacks adequate or secure housing and basic infrastructure, including water, sanitation, or hygiene services.

To examine the role of the urban built environment in the emergence and reemergence of infectious diseases that affect human health, the National Academies of Sciences, Engineering, and Medicine planned a public workshop. This publication summarizes the presentations and discussions from the workshop



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Prevention and Control of Infections in Hospitals: Practice and Theory

 Infectious Diseases  Comments Off on Prevention and Control of Infections in Hospitals: Practice and Theory
Mar 032019

This volume offers extensive information on preventive and infection surveillance procedures, routines and policies adapted to the optimal infection control level needed to tackle today’s microbes in hospital practice. It especially focuses on preventive measures for serious hospital infections. Each chapter includes a practical section that addresses the main aspects of procedures and treatment, and a theoretical section that contains updated documentation that can be used for further study, or to help select infection control measures.

Infection control concerns all healthcare professional working directly or indirectly with patients; in diagnosis, treatment, isolation measures, operations, equipment, drugs, cleaning, textiles, transport, porter service, food and water, building and maintenance, etc.

Hygiene and environmental control is central to infection prevention for patients, visitors and staff alike. Good hygienic practices, individual infection control, well implemented and frequent environmental cleaning, and a high professional standard of hygiene in the treatment and care of patients, are essential to patient safety and a safe working environment. Addressing this essential topic, this book is intended for doctors, nurses and other healthcare workers, students in health-related subjects, hospital managers and health bureaucrats, as well as patients and their families.

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Neuroviral Infections: General Principles and DNA Viruses

 Infectious Diseases, Neurology/Neurosurgery  Comments Off on Neuroviral Infections: General Principles and DNA Viruses
Feb 252019

Viral infections of the central nervous system or neurotropic viruses are often lethal. Understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book provides in-depth information about each individual virus, the diseases they cause, and the mechanisms of spread of those diseases.

Addressing both clinical and basic science aspects, the text covers such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host pathogen immune interaction as well as disease detection, treatment, and prevention.



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Nuclear Medicine in Tropical and Infectious Diseases

 Infectious Diseases, Nuclear Medicine  Comments Off on Nuclear Medicine in Tropical and Infectious Diseases
Feb 152019

“More than half of the world’s population is at risk of the tropical diseases malaria, leprosy, schistosomiasis, lymphatic filariasis, onchocerciasis, Chagas’ disease, African trypanosomiasis and leishmaniasis and half a billion are infected with at least one of these diseases”. J. H. F. Remme, World Health Organisation, 1993. “If it is true that science is not limited by frontiers and all research Institutions then belong to mankind, so it is natural for each Institution to be responsible for the problems of those who live in the geographic area under its influence. There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology. It is the duty of each Institution to study the particular aspects concerning its geographic region, as missing links of the chain of universal knowledge may be found there.” H. L. de Oliveira, fonner Rector of the University ofSiio Paulo, 1967. “Nuclear Medicine is cost effective, especially in the developing countries. ( … ).
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Infectious Complications in Transplant Recipients

 Infectious Diseases  Comments Off on Infectious Complications in Transplant Recipients
Feb 112019

Infectious Complications in Transplant Patients has been uniquely designed and formatted to address issues and trends pertaining to pathogens deemed important in critically ill transplant patients. The chapters have been carefully selected so as to direct the focus of the book towards current approaches to controversial, emerging or topical problems in these patients. Each chapter has been authored by a North American and a European specialist. This format serves to impart an added dimension reflective of the diversity of opinions and practices pertaining to unresolved or controversial issues. The authors are recognized experts in their respective fields.
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2019 Nelson’s Pediatric Antimicrobial Therapy (25th Edition) – January 2019 Release

 Infectious Diseases, Pediatrics  Comments Off on 2019 Nelson’s Pediatric Antimicrobial Therapy (25th Edition) – January 2019 Release
Feb 102019
This best-selling and widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of all infectious diseases in children.

For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices. Drug descriptions cover pediatric-appropriate antimicrobials and include complete information about dosing regimens. In response to growing concerns about overuse of antibiotics, the program includes guidelines on when not to prescribe antibiotics.

Now in color to help you find the best options quickly!

New in the 25th edition:

•    Includes recommendations for new intravenous broad-spectrum beta-lactam/beta-lactamase inhibitor combinations.
•    Provides options for treatment of increasing resistance in Escherichia coli for urinary tract infections.
•    Includes updates for management of diarrhea, including recommendations for Giardia with tinidazole and nitazoxanide as drugs of choice, based on the new Infectious Diseases Society of America (IDSA) guidelines.
•    Clarifies specific, new, and evolving recommendations about antifungal therapeutic drug levels for several invasive fungal infections, particularly in immunocompromised children.
•    Reorganizes antiviral table for easier reading: common viral pathogens are in one table and HIV, hepatitis B, and hepatitis C are in a second table.
•    Provides guidance for neonates during the ongoing cefotaxime shortage, including alternatives to achieve similar antibacterial activity in similar tissue sites, with a similar safety profile.
•    Includes updates, such as new information on drug therapy and steroid therapy for neurocysticercosis, incorporating the new IDSA and American Society of Tropical Medicine and Hygiene guidelines.
•    Incorporates new IDSA coccidioidomycosis guidelines in updated recommendations.
•    Simplifies navigation with color-coded tabs and tables that make it easier to find the best treatment options for susceptibility of bacterial, fungal, viral, and parasitic pathogens.


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Fighting Infection in the 21st Century

 Infectious Diseases  Comments Off on Fighting Infection in the 21st Century
Feb 092019

The 20th century has seen improvements in both public health and disease prevention which, in turn, have had a dramatic impact on our lives. Success in preventing infection by vaccination and treating infection with antibiotics led some to believe that infectious disease was a thing of the past. However, the adaptability of pathogens and the emergence of new diseases has presented microbiologists with a fresh set of challenges as we enter the new millennium. While celebrating past successes and highlighting developing problems, this volume aims to address some of the issues facing microbiologists in the future. Covering a wide range of topics, it will provide an invaluable resource for microbiologists and an excellent reference for advanced students.Content: Chapter 1 The Global Threat of Emerging Infectious Diseases (pages 1–16): Brian W.J. MahyChapter 2 Can Molecular Techniques be Used in the Prevention of Contamination of Processed Food by Pathogens? (pages 17–36): Thomas J. Humphrey, Gilbert Domingue and Peter H. StephensChapter 3 Is Global Clean Water Attainable? (pages 37–60): Jamie Bartram and Jose HuebChapter 4 Vaccine Development: Past, Present and Future (pages 61–71): Coenraad F.M. HendriksenChapter 5 Live Attenuated Vectors: Have they Delivered? (pages 72–86): Myron M. Levine, James E. Galen, Eileen Barry, Carol Tacket, Karen Kotloff, Oscar Gomez?Duarte, Marcela Pasetti, Thames Pickett and Marcelo SzteinChapter 6 New Malaria Vaccines: The DNA?MVA Prime?Boost Strategy (pages 87–96): Adrian V.S. HillChapter 7 Prospects for New and Rediscovered Therapies: Probiotics and Phage (pages 97–132): Stig BengmarkChapter 8 Vaccine Production in Plants (pages 133–142): Garry C. WhitelamChapter 9 Conserved Epitopes in Bacterial Lipopolysaccharides and Cross?Reactive Antibodies in the Treatment of Endotoxicosis and Gram?Negative Septic Shock (pages 143–178): Sven Muller?Loennies, Franco di Padova, Lore Brade, Didier Heumann and Ernst Theodor RietschelChapter 10 Biological Terrorism (pages 179–182): Paul TaylorChapter 11 Characterization of Bacterial Isolates with Molecular Techniques: Multilocus Sequence Typing (pages 183–197): Martin C.J. MaidenChapter 12 Lessons from the First Antibiotic Era (pages 198–216): Alexander TomaszChapter 13 New Strategies for Identifying and Developing Novel Vaccines: Genome?Based Discoveries (pages 217–236): Ling Lissolo and Marie?Jose Quentin?MilletChapter 14 Are Molecular Methods the Optimum Route to Antimicrobial Drugs? (pages 237–258): Frank C. Odds
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The Infectious Diseases Manual, Second Edition

 Infectious Diseases  Comments Off on The Infectious Diseases Manual, Second Edition
Feb 062019

The Infectious Diseases Manual is a concise and up-to-date guide to infectious diseases, medical microbiology and antibiotic prescribing”I have no hesitation in recommending this book to practitioners of all grades.”Journal of Hospital Infection”…..a valuable companion…….should not be missing in any medical library.”Infection”…… an excellent and extremely portable reference text…” Journal of Medical MicrobiologyWHY BUY THIS BOOK?Invaluable source of reference for day-to-day clinical useIntegrated information about clinical infectious diseases, microbiology and antibiotic prescribingClear and systematic layout using a standard format for each section allowing rapid access to key informationContent: Chapter 1 Introduction (pages 1–13): Chapter 2 Upper Respiratory Tract Infections (pages 15–22): Chapter 3 Lower Respiratory Tract Infections (pages 23–36): Chapter 4 Mycobacteria and Mycobacterial Infections (pages 37–48): Chapter 5 Cardiac Infections (pages 49–56): Chapter 6 Gastrointestinal Infections (pages 57–69): Chapter 7 Hepatitis (pages 70–76): Chapter 8 Urinary Tract Infection (UTI) (pages 77–81): Chapter 9 Gynaecological and Obstetric Infections (pages 82–85): Chapter 10 Sexually Transmitted Diseases (STDs) (pages 86–95): Chapter 11 CNS Infections (pages 96–103): Chapter 12 Eye Infections (pages 104–110): Chapter 13 Skin Infections (pages 111–119): Chapter 14 Bone and Joint Infections (pages 120–125): Chapter 15 Paediatric Infections (pages 126–142): Chapter 16 Human Immune Deficiency Virus (HIV) Infection and Acquired Immune Deficiency Syndrome (AIDS) (pages 143–169): Chapter 17 Infections in the Immunocompromised Host (pages 170–178): Chapter 18 Fever (pages 179–184): Chapter 19 Septic Shock (pages 185–188): Chapter 20 Pre?Travel Advice (pages 189–205): Chapter 21 Tropical Medicine and the Returning Traveller (pages 206–228): Chapter 22 Protozoa (pages 229–232): Chapter 23 Helminths (pages 233–244): Chapter 24 Staphylococci (pages 245–253): Chapter 25 Streptococci and Their Relatives (pages 254–262): Chapter 26 Aerobic Gram?Positive Rods (pages 263–272): Chapter 27 Coliforms (Syn. Enterobacteria, Enterobacteriaceae) (pages 273–284): Chapter 28 Vibrios (pages 285–287): Chapter 29 Campylobacters (pages 288–290): Chapter 30 Pseudomonads (pages 291–295): Chapter 31 Fastidious Gram?Negative Organisms (pages 296–311): Chapter 32 Anaerobes (pages 312–321): Chapter 33 Spirochaetes (pages 322–328): Chapter 34 Mycoplasmas, Chlamydias and Rickettsias (pages 329–333): Chapter 35 Virology (pages 334–362): Chapter 36 Fungi (pages 363–377): Chapter 37 Antibiotics: Theory, Usage and Abuse (pages 379–389): Chapter 38 Antibiotics: Classification and Dosing Guidelines (pages 391–414):
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Red Book Pediatric Infectious Diseases Clinical Decision Support Chart

 Infectious Diseases, Pediatrics  Comments Off on Red Book Pediatric Infectious Diseases Clinical Decision Support Chart
Feb 062019

Among the most helpful and popular features of the Red Book are its tables, algorithms, charts, and graphs. To make these tools more accessible and user-friendly at the point of care, the American Academy of Pediatrics is pleased to introduce the new Red Book Pediatric Infectious Diseases Clinical Decision Support Chart.

This handy resource collects many of the most clinically useful tables, algorithms, and other items from the latest edition of Red Book and presents them in an enlarged, enhanced, colorized format that is lightweight, portable, and easy to navigate.

Additionally, new tables have been created exclusively for this chart, synthesizing important clinical information from the Red Book text.

15 information-rich topics include:

– Staphylococcal Infections
– Streptococcal Infections
– Diarrheal Infections
– Immunizations
– Antibiotic Prophylaxis
– Immune Globulin
– Kawasaki Disease
– Tuberculosis
– Lyme Disease
– Varicella-Zoster
– Zika
– Fungal Infections
– Genital and Neonatal Herpes
– Syphilis
– Immunocompromised Children and Adolescents

The content featured in these 15 tabs has been reviewed by the Red Book editors to ensure consistency with AAP policy.



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