Jun 082017
 

Pancreas, Kidney and Skin Regeneration (Stem Cells in Clinical Applications)


This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in diabetes, kidney and wound treatment. All chapters are contributed by pre-eminent scientists in the field and covers such topics as stem cells and cell therapy in the treatment of diabetes mellitus, kidney failure, wound and other skin aging diseases, characteristics of some kinds of stem/progenitor cells for therapy, future directions of the discussed therapies and much more. 

Pancreas, Kidney and Skin Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

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Jun 012017
 

Henrich’s Principles and Practice of Dialysis


By (author): Edgar Lerma MD

Improve your patients’ quality of life with evidence-based, practical guidance on every aspect of today’s dialysis.
 
For more than 20 years, Henrich’s Principles and Practice of Dialysis has been the go-to resource for comprehensive, accessible information on the challenges of managing the wide variety of patients who receive dialysis. This Fifth Edition brings you fully up to date with new chapters, a new eBook edition, two new editors and new contributors who offer practical experience and a fresh perspective.  Clearly written and unique in scope, it helps you meet the growing demand for this procedure by providing a solid foundation in both basic science and clinical application.

Key Features:

  • All chapters are fully updated and offer unparalleled coverage of the changing nature of modern dialysis practice.
  • A new chapter on pregnancy and dialysis addresses the unique needs of this special patient population.
  • A new chapter on cystic kidney disease and ESRD provides the latest information on complications that can lead to kidney failure.
  • Other new chapters include home hemodialysis, the wearable artificial kidney, and respiratory disorders in dialysis patients.
  • Sections cover technical and procedural considerations in hemodialysis and peritoneal dialysis, clinical considerations in the evaluation of dialysis patients, drugs and intoxications, dialysis in the pediatric population, and the business of dialysis.


Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:

  • Complete content with enhanced navigation
  • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
  • Cross-linked pages, references, and more for easy navigation
  • Highlighting tool for easier reference of key content throughout the text
  • Ability to take and share notes with friends and colleagues
  • Quick reference tabbing to save your favorite content for future use


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May 292017
 

Polycystic Kidney Disease (Colloquium Series on Integrated Systems Physiology)


By (author): Christian Riella, Peter G. Czarnecki, Theodore I. Steinman

This book reviews important aspects of polycystic kidney diseases, the latest scientific understanding of the diseases and syndromes, along with the therapies being developed. Cystic kidney diseases comprise a spectrum of genetic syndromes defined by renal cyst formation and expansion with variable extrarenal manifestations. The most prevalent disorder is the autosomal dominant polycystic kidney disease (ADPKD). It is the most common monogenetic disorder in humans and accounts for 4.4% of end-stage renal disease (ESRD) cases in the U.S. Patients inevitably progress to ESRD and require renal replacement therapy in the form of dialysis or transplantation. Through advancements in genomics and proteomics approaches, novel genes responsible for cystic diseases have been identified, further expanding our understanding of basic mechanisms of disease pathogenesis. The hallmark among all cystic genetic syndromes is the formation and growth of fluid-filled cysts, which originate from tubular epithelia of nephron segments. Cysts are the disease, and treatment strategies are being developed to target prevention or delay of cyst formation and expansion at an early stage, however no such therapy is currently approved.
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May 212017
 

Pediatric Nephrology for Primary Care


This clinical resource is purpose-built to help primary caregivers take a lead role in diagnosis, evaluation, and treatment of diverse pediatric kidney diseases. Diagnose and manage renal diseases with confidence. The resource book has clear, concise overviews of the full range of renal conditions you re likely to encounter; evidence-based discussion of each condition’s clinical course, pathogenesis, and etiology; expert management recommendations and valuable clinical pearls, tables, algorithms, and clinical calculators to help with differential diagnosis and patient workups; advice on when to treat vs when to refer; practical implications of recent research findings; and how-to diagnostic solutions. Contents include evaluating patient presentation; history and physical examination; examination of the urine; use of the clinical laboratory; imaging of the kidney and urinary tract; prenatal and perinatal diagnosis; guidelines for patient referral; proven approaches to common conditions; congenital abnormalities; urinary tract infection; hematuria and proteinuria; glomerular disease; renal tubular disease; water and electrolyte disorders; acute kidney injury; chronic renal failure; hypertension; genetic diseases; and kidney in systemic disease.
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May 172017
 

Renal Fibrosis (Contributions to Nephrology, Vol. 139)


This publication provides a synopsis of the rapid progress made in the field of renal cell biology during the last decade, progress which has resulted in a better conceptual understanding of the cellular and molecular mechanisms of fibrotic renal disease. These developments have provided new therapeutic choices and led to the discovery of gene-based therapeutic options. The topics covered in this book have been carefully selected from the immense number of aspects of the disease to provide essential information on the molecular basis of renal fibrosis. Individual chapters discuss topics such as proteinuria and tubulointerstitial injury, the roles and regulation of TGF-beta, chemokines, oxidant stress, matrix remodeling, significance of renal expression of NF-kappa, and the potential impact of cell death in renal fibrosis. Written so as to present the complex information as simply as possible, this publication will be a very useful tool for general health professionals involved in the fields of immunology and cell biology, as well as for clinicians and researchers within the fields of nephrology, pathology and matrix biology.
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May 132017
 

The Renin-Angiotensin-Aldosterone System: Methods and Protocols (Methods in Molecular Biology)


This volume discusses protocols that aid in measuring different components in the renin-angiotensin-aldosterone system (RAAS). The book also looks at the methods used to assess angiotensin peptides and discerning the influence of RAAS components on different mammalian diseases. The chapters cover topics such as the use of fluorescent substrate to measure ACE2 activity in the mouse abdominal aorta, blood pressure monitoring using the radio telemetry method, and the analysis of angiotensin metabolism in the kidney using mass spectrometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting edge and comprehensive, The Renin-Angiotensin-Aldosterone Systems: Methods and Protocols is a valuable resource that provides scientists and researchers with the best approaches to examine RAAS.

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Apr 302017
 

Renal and Urinary Proteomics: Methods and Protocols


Based on research and results from the international Human Kidney and Urine Proteome Project, this handbook and reference presents current methods and protocols for the analysis of human kidney and urine. The world’s leading experts cover everything from basic techniques for routine analysis to advanced methods for difficult samples or analytes. Written with the practitioner in mind, all the methods and techniques are described with step-by-step protocols backed by much valuable practical advice taken from real life experiments.
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Apr 172017
 

Kidney Development and Disease (Results and Problems in Cell Differentiation)


Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes.

Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.  

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Apr 152017
 

Surgical Aspects of Peritoneal Dialysis


This book aims to educate general and vascular surgeons on all pertinent aspects of peritoneal dialysis (PD). Most surgeons get very little training in residency on this topic, and the use of PD is growing around the world. Much of the book will focus on implantation techniques, especially laparoscopic insertions. The authors will describe the known adjunct procedures that have been shown to decrease dysfunction rates. 

The aim is to provide greater patient autonomy, a better quality of life, preservation of residual renal function and a higher survival advantage. 
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Apr 092017
 

Hemodialysis Access: Fundamentals and Advanced Management


?This comprehensive reference on the fundamentals of hemodialysis access creation and advanced management for maintenance is designed to meet the needs of all surgeons and physicians responsible for the treatment and care of patients undergoing dialysis. The book opens by discussing every aspect of dialysis access planning, including selection of the right access for the individual patient and access strategies. Hemodialysis access techniques, from the most basic to the most complex and unconventional, are then described step by step, and guidance is provided on follow-up. Detailed attention is also devoted to the challenging management of specific complications of dialysis access surgery, including failing hemodialysis access. The book includes a wealth of informative, high-quality images and illustrations, and the authors are prominent vascular surgeons, transplant surgeons, general surgeons, nephrologists, and interventional radiologists from across the United States.
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