May 212017
 

Pediatric Nephrology for Primary Care


This clinical resource is purpose-built to help primary caregivers take a lead role in diagnosis, evaluation, and treatment of diverse pediatric kidney diseases. Diagnose and manage renal diseases with confidence. The resource book has clear, concise overviews of the full range of renal conditions you re likely to encounter; evidence-based discussion of each condition’s clinical course, pathogenesis, and etiology; expert management recommendations and valuable clinical pearls, tables, algorithms, and clinical calculators to help with differential diagnosis and patient workups; advice on when to treat vs when to refer; practical implications of recent research findings; and how-to diagnostic solutions. Contents include evaluating patient presentation; history and physical examination; examination of the urine; use of the clinical laboratory; imaging of the kidney and urinary tract; prenatal and perinatal diagnosis; guidelines for patient referral; proven approaches to common conditions; congenital abnormalities; urinary tract infection; hematuria and proteinuria; glomerular disease; renal tubular disease; water and electrolyte disorders; acute kidney injury; chronic renal failure; hypertension; genetic diseases; and kidney in systemic disease.
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May 172017
 

Renal Fibrosis (Contributions to Nephrology, Vol. 139)


This publication provides a synopsis of the rapid progress made in the field of renal cell biology during the last decade, progress which has resulted in a better conceptual understanding of the cellular and molecular mechanisms of fibrotic renal disease. These developments have provided new therapeutic choices and led to the discovery of gene-based therapeutic options. The topics covered in this book have been carefully selected from the immense number of aspects of the disease to provide essential information on the molecular basis of renal fibrosis. Individual chapters discuss topics such as proteinuria and tubulointerstitial injury, the roles and regulation of TGF-beta, chemokines, oxidant stress, matrix remodeling, significance of renal expression of NF-kappa, and the potential impact of cell death in renal fibrosis. Written so as to present the complex information as simply as possible, this publication will be a very useful tool for general health professionals involved in the fields of immunology and cell biology, as well as for clinicians and researchers within the fields of nephrology, pathology and matrix biology.
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May 132017
 

The Renin-Angiotensin-Aldosterone System: Methods and Protocols (Methods in Molecular Biology)


This volume discusses protocols that aid in measuring different components in the renin-angiotensin-aldosterone system (RAAS). The book also looks at the methods used to assess angiotensin peptides and discerning the influence of RAAS components on different mammalian diseases. The chapters cover topics such as the use of fluorescent substrate to measure ACE2 activity in the mouse abdominal aorta, blood pressure monitoring using the radio telemetry method, and the analysis of angiotensin metabolism in the kidney using mass spectrometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting edge and comprehensive, The Renin-Angiotensin-Aldosterone Systems: Methods and Protocols is a valuable resource that provides scientists and researchers with the best approaches to examine RAAS.

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Apr 302017
 

Renal and Urinary Proteomics: Methods and Protocols


Based on research and results from the international Human Kidney and Urine Proteome Project, this handbook and reference presents current methods and protocols for the analysis of human kidney and urine. The world’s leading experts cover everything from basic techniques for routine analysis to advanced methods for difficult samples or analytes. Written with the practitioner in mind, all the methods and techniques are described with step-by-step protocols backed by much valuable practical advice taken from real life experiments.
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Apr 172017
 

Kidney Development and Disease (Results and Problems in Cell Differentiation)


Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes.

Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.  

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Apr 152017
 

Surgical Aspects of Peritoneal Dialysis


This book aims to educate general and vascular surgeons on all pertinent aspects of peritoneal dialysis (PD). Most surgeons get very little training in residency on this topic, and the use of PD is growing around the world. Much of the book will focus on implantation techniques, especially laparoscopic insertions. The authors will describe the known adjunct procedures that have been shown to decrease dysfunction rates. 

The aim is to provide greater patient autonomy, a better quality of life, preservation of residual renal function and a higher survival advantage. 
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Apr 092017
 

Hemodialysis Access: Fundamentals and Advanced Management


?This comprehensive reference on the fundamentals of hemodialysis access creation and advanced management for maintenance is designed to meet the needs of all surgeons and physicians responsible for the treatment and care of patients undergoing dialysis. The book opens by discussing every aspect of dialysis access planning, including selection of the right access for the individual patient and access strategies. Hemodialysis access techniques, from the most basic to the most complex and unconventional, are then described step by step, and guidance is provided on follow-up. Detailed attention is also devoted to the challenging management of specific complications of dialysis access surgery, including failing hemodialysis access. The book includes a wealth of informative, high-quality images and illustrations, and the authors are prominent vascular surgeons, transplant surgeons, general surgeons, nephrologists, and interventional radiologists from across the United States.
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Apr 052017
 

Laparoscopic Donor Nephrectomy: A Step-by-Step Guide


This book explains the development of various laparoscopic donor nephrectomy (LDN) techniques, which can be performed via the retroperitoneal or the transperitoneal approach. It provides a step-by-step explanation of LDN, including details of intricacies such as port positioning, dissection steps, securing the hilum and retrieval. It also reviews new techniques like robotic donor nephrectomy and single-port donor nephrectomy. Lastly, it explores the non-technical but equally important issues of donor work-up and legal and social aspects.

LDN is a unique surgical procedure in which the surgeon operates on an individual who is not a patient but someone donating out of altruistic motives, and it has to be “zero error” for the safety of the graft, donor and the recipient. This handbook is a valuable resource for urologists, general and transplant surgeons as well as anesthesiologists and medical social workers working in the field.

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Apr 012017
 

Atlas of Ultrasonography in Urology, Andrology, and Nephrology


This book provides the latest recommendations for ultrasound examination of the entire urogenital system, particularly in the male. The coverage encompasses the role of ultrasound in imaging of disorders of the kidneys, urinary tract, prostate, seminal vesicles, bladder, testes, and penis, including male infertility disorders. In addition, detailed consideration is given to intraoperative and interventional ultrasound and recently developed ultrasound techniques. Each chapter defines the purpose of and indications for ultrasound, identifies its benefits and limitations, specifies the technological standards for devices, outlines performance of the investigation, establishes the expected accuracy for differential diagnosis, and indicates the reporting method. Most of the recommendations are based on review of the literature, on previous recommendations, and on the opinions of the experts of the Imaging Working Group of the Italian Society of Urology (SIU) and the Italian Society of Ultrasound in Urology, Andrology, and Nephrology (SIEUN). The book will be of value for all physicians involved in the first-line evaluation of diseases of the renal/urinary system and male genital disorders.
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Mar 312017
 

Principles and Practice of Dialysis (Principles & Practice of Dialysis)


By (author): William L. Henrich MD

This book is an evidence-based review of the practical challenges of dealing with patients receiving dialysis. The first section covers technical and procedural considerations such as choosing the hemodialysis membrane and choosing the best dialysis option. The second section covers clinical considerations such as infection and the treatment of specific renal disease complications. The book includes numerous illustrations and tables and drug charts for dialysis patients.

This edition’s current outcomes chapter has been expanded to include patient depression and improving quality of care. New chapters cover dialysis in the ICU, valvular heart disease, and pre-emptive renal transplantation.

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