Contents
1 Global Burden of Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Jacques Ferlay, Clarisse He´ ry, Philippe Autier,and Rengaswamy Sankaranarayanan
2 Breast Cancer Biology and Clinical Characteristics . . . . . . . . . . . . . . 21
Amanda I. Phipps and Christopher I. Li
3 In situ Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Brian L. Sprague and Amy Trentham-Dietz
4 Endogenous Hormones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
Amanda I. Phipps and Christopher I. Li
5 Exogenous Hormones. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Christopher I. Li and Elisabeth F. Beaber
6 Reproductive Factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119
Mats Lambe
7 Physical Activity and Anthropometric Factors . . . . . . . . . . . . . . . . . . 137
Katherine D. Henderson, Jennifer Prescott,and Leslie Bernstein
8 Diet and Nutrition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
Martin Lajous and Shumin M. Zhang
9 Environmental and Occupational Exposures . . . . . . . . . . . . . . . . . . . 183
Amanda I. Phipps, Dana Mirick, Christopher I. Li,and Scott Davis
10 Shift Work and Circadian Disruption. . . . . . . . . . . . . . . . . . . . . . . . . 223
Scott Davis and Dana K. Mirick
11 Non-Hormonal Medications and Chronic Diseases . . . . . . . . . . . . . . 243
Patricia F. Coogan
12 Male Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261
Ian S. Fentiman
13 Inherited Predisposition: Familial Aggregation and HighRisk Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277
Kathleen E. Malone and Kerryn W. Reding
14 Common Genetic Susceptibility Loci . . . . . . . . . . . . . . . . . . . . . . . . . 301
Mikkel Z. Oestergaard and Paul Pharoah
15 Mammographic Density as a Potential Surrogate Markerfor Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321
Norman F. Boyd, Lisa J. Martin, and Salomon Minkin
16 Breast Cancer Screening . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343
Karla Kerlikowske
17 Principles of Breast Cancer Therapy . . . . . . . . . . . . . . . . . . . . . . . . . 371
Allison W. Kurian and Robert W. Carlson
18 Breast Cancer Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389
Graham A. Colditz and Courtney Beers
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403
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VN:F [1.9.3_1094]
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VN:F [1.9.3_1094]
Univ. of North Carolina, Chapel Hill. Reference, for students and researchers. Discusses what needs to be considered when enrolling participants in studies of sexually transmitted diseases, what the common sources of measurement error in population-based studies of respiratory infections are, and the sources of data for epidemiologic studies of infectious diseases.
Contents
This book provides students with an overview of the principles and concepts of epidemiology and illustrates the complementary relationship between population-based science and the care of patients Thoroughly updated, this new edition features epidemiologic implications of bio-terrorism, “Patient Profiles” within each chapter, and USMLE clinical vignettes within the “Study Question” section of each chapter