Practical Medical and Surgical Management of Chronic Rhinosinusitis

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Oct 292019
 

This book is a comprehensive compendium on the medical and surgical treatment of chronic rhinosinusitis (CRS), with or without polyposis. Detailed coverage is provided of a wide range of topics, including medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period and specific medical therapeutic classes currently employed in CRS patients. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects and available clinical efficacy data and emphasizes practical management pearls and pitfalls. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined. The book will be a valuable resource for practicing general otolaryngologists, rhinologists and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners and nurses involved in the care of CRS patients.

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The Drug Development Process: Increasing Efficiency and Cost-Effectiveness (Drugs and the Pharmaceutical Sciences)

 Pharmacology, Uncategorized  Comments Off on The Drug Development Process: Increasing Efficiency and Cost-Effectiveness (Drugs and the Pharmaceutical Sciences)
Oct 272019
 

Containing contributions from the many disciplines involved in a drug’s evolution, this timely volume examines the entire pharmaceutical development process, emphasizing approaches to increasing efficiency and reducing costs.

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Organism Models of Autism Spectrum Disorders (Neuromethods)

 Neurology/Neurosurgery, Uncategorized  Comments Off on Organism Models of Autism Spectrum Disorders (Neuromethods)
Oct 272019
 

As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab.

Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.

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Clinical Cardiac Electrophysiology in Clinical Practice

 Cardiovascular, Uncategorized  Comments Off on Clinical Cardiac Electrophysiology in Clinical Practice
Oct 272019
 

Cardiac Electrophysiology (EP) is a highly specialized, complex and growing field of cardiology. As understanding of the evaluation of treatment of arrhythmias continues to advance, learning and understanding the principles of EP in order to provide the best possible treatments for patients can be a daunting task. The Manual of Clinical Cardiac Electrophysiology is a guide to the clinical diagnosis and treatment of cardiac arrhythmias that meets this need. With a scientific, practical, and multi-disciplinary approach, the book establishes the foundation of the cardiac electrophysiology and provides multimedia illustrations to facilitate and enhance understanding. These illustrations will come directly from real case studies, to provide an authentic look at each principle of EP. Since the world of EP moves so fast, and arrhythmias are diagnosed and treated in real time, it is often difficult to learn EP from static texts, images and diagrams. This book is designed to be accessible enough to serve as an introduction to EP, but advanced enough to serve as a guide for experienced practitioners. EP students of all levels, including medical students, residents, fellows, mid-level providers, nurses, technologist, primary care providers, cardiologists and electrophysiologists will find value in the Manual of Clinical Cardiac Electrophysiology.

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Macromolecular Anticancer Therapeutics

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Oct 182019
 

In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic concentrations, intrinsic or acquired resistance to the treatment with currently available agents via genetic and epigenetic mechanisms, and toxicity. As a result, cancer therapy using conventional therapeutics and different types of treatment regimens using this therapeutics has not led to a convincing survival benefit of the patients. In this context, Macromolecular therapeutics offer several advantages over conventional low molecular therapeutics by various ways such as, enable the use of larger doses of these agents by limiting the toxicity, by enhanced permeability and retention into tumors, by tumor targeting using tumor-specific antibodies, by specific inhibition of oncogenes using anticancer oligonucleotides etc. Cancer treatment using this macromolecular therapeutics has considerably improved the survival benefit for patients. As a result, various macromolecular therapeutics are already commercialized or are under clinical development. Although we are far from a real magic bullet today, looking at the pace of research and current success in this field of macromolecular therapeutics, it appears that we are approaching a magic bullet for the efficient treatment of cancer. Thus, we believe that the subject of this book is very timely, and that the book will fill an unmet need in the market.
This book is unique and assembles various types and aspects of macromolecular anticancer therapeutics for cancer therapy in one shell and conveys the importance of this interdisciplinary field to the broad audience. Thus, in a nutshell, this book details the basics of cancer, and various therapeutic strategies such as those based on macromolecular therapeutics hence can become an important reference for practitioners, oncologists, medical pharmacologists, medicinal chemists, biomedical scientists, experimental pharmacologists, pharmaceutical technologists, and particularly it can essentially become a handbook of macromolecular therapeutics for cancer therapy for graduates, post-graduates and Ph.D. students in these fields.

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Introduction to Nursing Informatics, 4th edition

 Nursing, Uncategorized  Comments Off on Introduction to Nursing Informatics, 4th edition
Oct 182019
 

This 4th edition of Introduction to Nursing Informatics is designed for use by practicing nurses and students in undergraduate programs of study. It presents the fundamental concepts of Nursing Informatics, and includes a number of contributions from leading experts who have practiced in the field of informatics over a number of years. The information is presented and integrated in a purposeful manner to encourage you to explore key concepts, starting with the fundamental concepts and then progressing on to core concepts and practice applications in the later sections. Briefly, the word CARE is presented as an acronym for Connected Health, Administration, Research and Education and the book is organised in sections with these sub themes. Critically, the content is linked with case-based examples to contextualize the theory presented.

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Erectile Dysfunction in Hypertension and Cardiovascular Disease: A Guide for Clinicians

 Cardiovascular, Uncategorized  Comments Off on Erectile Dysfunction in Hypertension and Cardiovascular Disease: A Guide for Clinicians
Oct 142019
 

This concise guide to the often overlooked association between erectile dysfunction and hypertension/cardiovascular disease covers a wide range of aspects of importance to the clinician. It examines the impact of antihypertensive drug therapy on erectile function and explains how the management of erectile dysfunction in hypertensive patients depends on a variety of factors. Different treatment approaches are described, including lifestyle modification, PDE-5 inhibitors and other novel agents and behavioral therapy and helpful therapeutic algorithms are presented. A further focus of the book is the potential role of erectile dysfunction as an early diagnostic indicator of asymptomatic coronary artery disease and a prognostic marker for cardiovascular events. In addition, key background information is supplied on epidemiology and pathophysiology, and the significance of erectile dysfunction in different patient groups, such as the elderly and those with chronic kidney disease, is examined. Erectile dysfunction is a major public health problem affecting more than ten percent of the general male population and is now considered to be predominantly of vascular origin. This book will be informative and of practical value for all practitioners responsible for caring for the very many patients who experience erectile dysfunction in the setting of hypertension and cardiovascular disease.

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Ophthalmology and the Ageing Society

 Ophthalmology, Uncategorized  Comments Off on Ophthalmology and the Ageing Society
Oct 052019
 

The ageing of the world’s population is one of the major achievements of modern society. By 2050, an estimated 2 billion people will be aged 60 years or over. However, ageing poses major challenges and this is especially true for the field of ophthalmology, given that the major eye diseases – age-related macular degeneration, glaucoma, and cataract – predominantly affect the elderly. The challenges facing ophthalmology in an ageing society have not previously been addressed in a comprehensive way, although there are common denominators of the various eye diseases that affect the elderly. This book provides such a comprehensive overview encompassing epidemiology, risk factors, current treatment and prophylaxis, disability, co-morbidity, and the impact on quality of life. World leaders in their respective fields provide state-of-the-art knowledge on the geriatric aspects of ophthalmology that will help to improve the management of this growing patient population.
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Enhancing Early Child Development: A Handbook for Clinicians

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Oct 052019
 

Early childhood development refers to the skills that children acquire within their first five years of life, which lay the foundation for future learning. Children need care and support to stimulate their growth and healthy development. The stimulation of language, understanding, personal, social and motor skills of the child are important at an early age and it is one of the primary physicians’ responsibilities to give proper advice to parents on how to promote their children’s physical and mental development. Enhancing Early Child Development: A Handbook for Clinicians is a quick reference guide for pediatricians, clinicians, and pediatric nurse practitioners that aims at promoting early stimulation and intervention for optimizing development of normal children as well as children with cerebral palsy and autism. Designed to be used in daily practice, this book will provide counsel for clinicians, parents and caregivers and advise them on the appropriate methods to enhance their child’s development at different ages based on their health condition. In addition, Enhancing Early Child Development: A Handbook for Clinicians, incorporates a summary of the manual entitled “Counsel the Family on Care for Child Development” developed by UNICEF and WHO, which addresses child development in low resource countries.
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Principles of Miniaturized ExtraCorporeal Circulation: From Science and Technology to Clinical Practice

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Sep 302019
 


Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation while serving as a safe perfusion technique for open heart surgery with cardiopulmonary bypass. The book aims to provide an up-to-date and comprehensive overview covering practical advice on how to use MECC systems for those new to the field as well as tips, pitfalls, results, and latest developments. It also offers a systematic review of all published studies on a variety of MECC systems. The book will enable physicians to gain a better understanding of these new systems as well as to understand the rationale for their use in cardiac surgery. MECC requires a multidisciplinary approach, and this book will serve as an essential reference for all health care professionals working in the cardiac surgical operating room, in particular cardiothoracic surgeons, anesthesiologists, and perfusionists.
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