Adulthood and Aging: Research on Continuities and Discontinuities

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Sep 162019
 

In this volume distinguished scholars explore and apply the theoretical models of continuity and discontinuity to their research in adult development. The chapters address the different ways in which continuity is affected by change over the life course, as well as how individuals negotiate and maintain crucial continuities by adaptive change. Topics include adult life crises, illness, sibling relationships, and gender identity. Each chapter is followed by an insightful commentary. This book is a tribute to Bernice L. Neugarten for her contributions to the field of adult development, which includes the concept of continuities. Contributors include W. Andrew Achenbaum, Robert H. Binstock, James Birren, Bertram J. Cohler, Margaret Hellie Huyck, Boaz Kahana, Eva Kahana, Sheldon S. Tobin, Lillian E. Troll, Steven H. Zarit, and others.
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Biophysical Regulation of Vascular Differentiation and Assembly

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Sep 092019
 


The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisitely tuned by biophysical cues from the microenvironment, yet the scientific understanding of such cellular environments is still in its infancy.
Comprehending these processes sufficiently to manipulate them would pave the way to controlling blood vessel growth in therapeutic applications. This book assembles the works and views of experts from various disciplines to provide a unique perspective on how different aspects of its microenvironment regulate the differentiation and assembly of the vasculature. In particular, it describes recent efforts to exploit modern engineering techniques to study and manipulate various biophysical cues.

Biophysical Regulation of Vascular Differentiation and Assembly provides an interdisciplinary view of vasculature regulation by various biophysical cues and presents recent advances in measuring and controlling such parameters. This book will be of interest to biologists, biophysicists and engineers who work with vascular differentiation and assembly.

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Clinical Cases in Periodontics

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Aug 152019
 

Wiley-Blackwell’s “Clinical Cases” series is designed to recognize the centrality of clinical cases to the profession by providing actual cases with an academic backbone. Clinical Cases in Periodontics describes the core principles of periodontics and demonstrates their practical, every-day application through a range of representative cases building from the simple to the complex and from the common to the rare. This unique approach supports the new trend in case-based and problem-based learning, thoroughly covering topics ranging from infant oral health to complex pulp therapy. Highly illustrated in full color, Clinical Cases in Periodontics utilizes a format that fosters independent learning and prepares the reader for case-based examinations. The book presents actual clinical cases, accompanied by academic commentary, that question and educate the reader about essential topics in periodontics. The book begins with a set of cases illustrating the most common diagnoses and the key decisions and evaluations leading up to them. Subsequent chapters continue in this style, presenting exemplary cases as the basis of discussing various treatment options including surgical and non-surgical treatment, regenerative therapy, mucogingival therapy, and interdisciplinary treatments. Concluding chapters cover implant site development and general prevention of such periodontal diseases. Clinical Cases in Periodontics’s case-based format is particularly useful for pre-doctoral dental students, post-graduate residents and practitioners, both as a textbook from which to learn about the challenging and absorbing nature of periodontology, and also as a reference tool to help with treatment planning when complex cases present in the dental office.

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Prove It! Evidence-Based Analysis of Common Spine Practice

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Aug 092019
 

Prove It! Evidence-Based Analysis of Common Spine Practice offers spine surgeons detailed guidance in using the principles of evidence-based medicine in treatment decisions. The book presents a unique collection of 31 case studies in which noted experts review a patient’s signs and symptoms and relevant images to determine the best-fitting diagnosis and then to develop a treatment plan based on the best available published evidence. The case-based approach allows the reader to see how evidence-based medicine can be directly and practically applied to the care of patients with a variety of disorders.

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Bioethics, Public Health, and the Social Sciences for the Medical Professions: An Integrated, Case-Based Approach

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Jul 282019
 

This unique textbook utilizes an integrated, case-based approach to explore how the domains of bioethics, public health and the social sciences impact individual patients and populations. It provides a structured framework suitable for both educators (including course directors and others engaged in curricular design) and for medical and health professions students to use in classroom settings across a range of clinical areas and allied health professions and for independent study.
The textbook opens with an introduction, describing the intersection of ethics and public health in clinical practice and the six key themes that inform the book`s core learning objectives, followed by a guide to using the book. It then presents 22 case studies that address a broad spectrum of patient populations, clinical settings, and disease pathologies. Each pair of cases shares a core concept in bioethics or public health, from community perspectives and end-of-life care to medical mistakes and stigma and marginalization. They engage learners in rigorous clinical and ethical reasoning by prompting readers to make choices based on available information and then providing additional information to challenge assumptions, simulating clinical decision-making. In addition to providing a unique, detailed clinical scenario, each case is presented in a consistent format, which includes learning objectives, questions and responses for self-directed learning, questions and responses for group discussion, references, and suggested further reading. All cases integrate the six themes of patient- and family-centered care; evidence-based practice; structural competency; biases in decision-making; cultural humility and awareness of the culture of medicine; and justice, social responsibility and advocacy. The final section discusses some challenges to evaluating courses and learning encounters that adopt the cases and includes a model framework for learner assessment.

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Controlled Substance Management in Chronic Pain: A Balanced Approach

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Jul 192019
 

This comprehensive guide covers prescribing controlled substances for patients with acute or chronic pain and provides a balanced discussion on appropriate treatment, addiction, safety and complications. Chapters feature evidence-based strategies and clinical modalities that address diagnostic challenges, treatment guidance, alternatives to opioid management and the significant legal risks within the current regulatory environment. Authored by leaders in pain medicine, physicians and appropriate health care professionals will find Controlled Substance Management in Chronic Pain to be an indispensable resource.

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Chromatin Protocols: Second Edition

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Jul 142019
 

Significant advancements have been made in the study of chromatin structure and function over the past fifty years but none as spectacular as those made in the last decade due to the development of novel techniques and the ability to sequence large stretches of DNA. In Chromatin Protocols, Second Edition, expert researchers delineate these cutting-edge techniques via step-by-step laboratory methods and protocols, which encompass a wide array of topics from the isolation of nucleosomes, assembly of nucleosomes and study of the basic chromatin structure to detailed analysis of histone modifications and chromatin function. Written in the highly successful Methods in Molecular Biology™ series style, chapters include brief introductions to the subjects, lists of the necessary materials and reagents, readily reproducible protocols, and Notes sections which highlight tips on troubleshooting and avoiding known pitfalls.Comprehensive and up-to-date, Chromatin Protocols, Second Edition is a valuable tool for scientists studying various aspects of chromatin function and an ideal guide to aid in the development of new techniques as well as new ideas in the field of chromatin biology.
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Vascular Liver Disease: Mechanisms and Management

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Jul 132019
 

Vascular Liver Disease: Mechanisms and Management covers all of the disease entities that stem from abnormalities that affect the hepatic vasculature. This multi-authored text includes the mechanisms and management of intrahepatic vascular disease, including the most common cause of vascular disease of the liver, cirrhosis. Other less common diseases of the liver vasculature are also covered such as sinusoidal obstruction syndrome (previously known as veno-occlusive disease), portal vein thrombosis, the Budd-Chiari syndrome and congenital vascular malformations. These entities, although rare, are a challenge to physicians and physician scientists. Although many textbooks have been written on the consequences of cirrhosis on the liver vasculature, this is the only volume that focuses on the liver vasculature as a separate entity, providing an innovative approach to liver disease management. Vascular Liver Disease: Mechanisms and Management will be of great value to clinical investigators and basic scientists interested in the liver circulation as well as clinical gastroenterologists and hepatologists, hepatobiliary surgeons and transplant surgeons, and to interventional radiologists with a particular interest in the liver.
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Frozen Section Library: Bone

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Jul 102019
 

Frozen sections are performed while a patient is undergoing surgery as a basis for making an immediate diagnosis that will impact treatment decisions. Frozen section diagnosis is often a highly demanding situation for the pathologist who must render a diagnosis quickly for the patient and surgeon.The Frozen Section Library series will provide concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario.Omar Hameed, M.D., is an Assistant Professor, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.Shi Wei, M.D.,Ph.D., is an Assistant Professor, Department of Pathology, University of Alabama, Birmingham, Alabama, USA.Gene P. Siegal, M.D., Ph.D., is a Robert W. Mowry Endowed Professor of Pathology & Director, Division of Anatomic Pathology; Executive Vice-Chair of Pathology – UAB Health System; Sr. Scientist, UAB Comprehensive Cancer Center & the Gene Therapy Center, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alamaba, USA.Gene P. Siegal, M.D., Ph.D., is a Robert W. Mowry Endowed Professor of Pathology & Director, Division of Anatomic Pathology; Executive Vice-Chair of Pathology – UAB Health System; Sr. Scientist, UAB Comprehensive Cancer Center & the Gene Therapy Center, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alamaba, USA.Gene P. Siegal, M.D., Ph.D., is a Robert W. Mowry Endowed Professor of Pathology & Director, Division of Anatomic Pathology; Executive Vice-Chair of Pathology – UAB Health System; Sr. Scientist, UAB Comprehensive Cancer Center & the Gene Therapy Center, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alamaba, USA.
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Contrast Echocardiography: Compendium for Clinical Practice

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Jul 062019
 


This book provides a comprehensive overview of the practical aspects of contrast echocardiography. It also covers all the material in the guidelines published by the American Society of Echocardiography (ASE) in 2018 and the recommendations set out by the European Association of Cardiovascular Imaging (EACVI) in 2017. Contrast echocardiography at present is only used in 5-10% of cases, but this is expected to grow rapidly following the recommendations of the ASE and EACVI. The chapters cover the approved indications and provide practical advice on how to administer the contrast agents and how to optimize the recordings as well as how to deal with the pitfalls. The reader will find all the information on how to use contrast agents for assessment of shunts, LV volumes and function as well as myocardial diseases and masses. Detailed protocols are included for stress echocardiography and myocardial perfusion imaging. Other topics covered include the use of contrast agents for coronary sonography and transesophageal echocardiography.
Contrast Echocardiography: Compendium for Clinical Practice comprehensively covers all aspects of the clinical use of contrast echocardiography and has been written by two cardiologists who share their experience from their high volume echo laboratories. One of the authors has been a member of both the ASE guidelines and EACVI recommendation writing groups. It is therefore, a critical text for echocardiographers and sonographers who perform echocardiography.

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