May 262016
 

Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry (RSC Green Chemistry)


Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation.


This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies.


Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.

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May 232016
 

Value Creation in the Pharmaceutical Industry: The Critical Path to Innovation


By (author): Alexander Schuhmacher, Markus Hinder, Oliver Gassmann

This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation.
A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes.
A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.
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May 232016
 

Disordered Pharmaceutical Materials


A one-stop resource for researchers and developers, this handbook and ready reference provides detailed, but not overloaded information — presenting the topic without unnecessarily complex formalism.
As such, it gives a systematic and coherent overview of disordered materials for pharmaceutical applications, covering fundamental aspects, preparation and characterization techniques as well as molecular modeling approaches for the target-oriented development of drug delivery systems based on amorphous solids. Chapters on the challenges of using these materials in large-scale processes in the pharmaceutical industry and on patenting issues round off the book.
For pharmaceutical and medicinal chemists, materials scientists, clinical physicists, and pharmaceutical laboratories looking to make better and more potent pharmaceuticals.
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May 222016
 

Workbook and Casebook for Goodman and Gilman’s The Pharmacological Basis of Therapeutics


By (author): Douglas Rollins, Donald Blumenthal

A new companion study guide to the most respected text in pharmacy education

Goodman & Gilman’s Workbook for Pharmacologic Therapeutics delivers concise, high-yield summaries of the world-renowned coverage of the actions and uses of therapeutic agents in relation to physiology and pathophysiology found in Goodman & Gilman’s The Pharmacological Basis of Therapeutics.

In order to maximize the learning and teaching experience, this unique review is packed with pedagogical aids such as learning objectives, summaries of key points, self-assessment Q&A, case vignettes, and a complete test bank in the final chapter. Perfect as a self-study guide or as a required classroom review, Goodman & Gilman’s Workbook for Pharmacologic Therapeutics contains features and content that will appeal to both students and professors.

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May 212016
 

The Mathematics and Biology of the Biodistribution of Radiopharmaceuticals – A Clinical Perspective


By (author): William C Klingensmith III

This book explores the mathematics and biology of the biodistribution of radiopharmaceuticals following their introduction into the body, but does so primarily from a clinical perspective – from the point of view of image interpretation and any associated image-derived quantification. All of the equations included in the book relate directly to the biodistribution of radiopharmaceuticals and are clinically useful, either conceptually or because of their value in quantifying a biological parameter, e.g., renal clearance. In particular, the more complex equations are not meant to be solved but instead are intended to provide a conceptual basis for the analysis of clinical images, especially those that are unusual and/or difficult to interpret. The efficacy of every diagnostic and therapeutic nuclear medicine procedure is critically dependent on the biodistribution of the radiopharmaceutical in question over time. This book will enable the reader to gain a sound understanding of the relevant mathematics and biology, and the clinical orientation ensures that it will be of value in enhancing clinical practice.

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May 212016
 

Drug Utilization Research: Methods and Applications


By (author): Monique Elseviers, Bj?rn Wettermark, Anna Birna Almarsd?ttir, Morten Andersen, Ria Benko, Marion Bennie, Irene Eriksson, Brian Godman, Janet Krska, Elisabetta Poluzzi, Kstja Taxis, Vera Vlahovic-Palcevski, Robert Vander Stichele

Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field of pharmacoepidemiology, but also to health outcomes research, pharmacovigilance and health economics.

Drug Utilization Research is a unique, practical guide to the assessment and evaluation of prescribing practices and to interventions to improve the use of medicines in populations. Edited by an international expert team from the International Society for Pharmacoepidemiology (ISPE), DUR is the only title to cover both the methodology and applications of drug utilization research and covers areas such as health policy, specific populations, therapeutics and adherence.

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May 202016
 

Community and Clinical Pharmacy Services: A step by step approach.


Features: Used Book in Good Condition
By (author): Ashley W. Ells, Justin Sherman

A STEP-BY-STEP GUIDE TO IMPLEMENTING ADVANCED PHARMACY SERVICES IN COMMUNITY AND CLINIC SETTINGS

Community and Clinical Pharmacy Services teaches pharmacy students and practicing pharmacists how to provide advanced levels of pharmacy services in community and clinic settings designed to help patients achieve specific health goals and treat common disease states. This unique text provides practical–rather than merely ideological–ways for pharmacists to utilize their extensive clinical knowledge and fill a major gap in American health care. It discusses barriers, necessary skills, required knowledge, and issues related to preparation, interventions, patient outcomes, economic aspects, and marketing considerations for therapeutic areas commonly addressed in the outpatient setting.

The beginning of the book delves into the general management skills necessary to provide and implement advanced patient care services, including documentation, patient interviewing, and medication therapy management. Important chapters discuss disease states that would most likely be amenable to development of pharmacy services, including:

  • Asthma
  • Smoking Cessation
  • Diabetes
  • Hypertension
  • Osteoporosis
  • Obesity

Also covered are immunizations, anticoagulation, and cardiometabolic services. The disease state chapters include learning aids such as summary points, first-hand accounts from experienced pharmacists who have implemented pharmacy services for that particular condition, a simulated patient case, and multiple-choice questions.

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May 182016
 

Dosage Calculations: A Ratio-Proportion Approach (includes Premium Web Site Printed Access Card)


By (author): Gloria D. Pickar, Amy Pickar-Abernethy

An excellent resource for anyone in or entering the field, market-leading DOSAGE CALCULATIONS: A RATIO-PROPORTION APPROACH, fourth edition, teaches you how to reduce errors and build your confidence in dosage calculation. It carefully examines both basic and advanced calculations, including intravenous medications and those specific to the pediatric patient. Extremely reader friendly, the book includes a comprehensive math review and a unique three-step method of calculating dosages that trains you to approach calculations logically. The new fourth edition reflects the latest drugs and protocol, regulations on medication abbreviations, medication administration technologies, and safe medication practices. Clinical simulations and Clinical Reasoning Skills scenarios based on QSEN principles help sharpen your clinical reasoning skills, while Section Examinations help prepare you for your future with test items formatted like graduate licensure examinations.
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May 182016
 

Mouse Models for Drug Discovery: Methods and Protocols (Methods in Molecular Biology)


With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. Herein, these models are applied to a wide field of disease areas, including diabetes, cardiovascular disease, skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinal disorders, as well as various behavioral models. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Practical and fully updated, Mouse Models for Drug Discovery: Methods and Protocols, Second Edition serves to equip the reader with an extensive overview of techniques to utilize the many possibilities of mice in the drug development process.
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May 172016
 

Pharmaceutical Nanotechnology: Fundamentals and Practical Applications


By (author): Costas Demetzos

This textbook explains the fundamental aspects of nanotechnology and fills the gap between bio-inspired nanotechnological systems and functionality of living organisms, introducing new insights to their physicochemical, biophysical and thermodynamic behaviour.
Addressed to all those involved in recent advances in pharmaceutics, this book is divided in three major parts: Part A refers to the physicochemical and thermodynamics aspects of nanosystems, wherein their biophysical behaviour is correlated with that of the cells of living organisms; Part B refers to the application of nanotechnology in imaging, diagnostics and therapeutics; Part C is focused on issues regarding safety and nanotoxicity of nanosystems, and the regulatory framework that surrounds these. The text promotes the concept that biophysics, thermodynamics and nanotechnology are considered to be emerging tools that, when approached within regulatory boundaries, provide new and integrated knowledge for the production of new medicines.
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