Apr 242017
 

Oxford Handbook of Clinical Pharmacy (Oxford Medical Handbooks)


Complementing the guidelines in the British National Formulary, the third edition of the Oxford Handbook of Clinical Pharmacy remains the indispensable guide to clinical pharmacy, providing all the information needed for practising and student pharmacists. It presents handy practical guidance in a quick-reference, bullet-point format to give the reader the knowledge and confidence needed to provide a clinical pharmacy service. Including key information on controlled drugs, adverse drug reactions, interactions, communication skills, and confidentiality, this extensively revised addition to the bestselling Oxford Handbook series is the fundamental pharmacy reference tool. It features chapters on adherence, anaphylaxis, clinical trials, herbal medicines, palliative care, patient management, pharmaceutical calculations, research, policy, and therapy related issues. Thoroughly revised and updated, the Oxford Handbook of Clinical Pharmacy includes brand new topics, including content on health coaching, residency and on-call, HIV and TB and mental health.
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Apr 222017
 

Katzung & Trevor’s Pharmacology Examination and Board Review,11th Edition (Katzung & Trevor’s Pharmacology Examination & Board Review)


By (author): Anthony Trevor, Bertram Katzung, Marieke Knuidering-Hall

Excel on medical pharmacology course exams and the boards with the help of the world’s bestselling pharmacology review book!

More than 800 Q&A

From the authors of pharmacology’s most trusted textbook, Katzung & Trevor’s Basic & Clinical Pharmacology, this authoritative resource delivers a clear, concise review of fundamental concepts backed by more than 800 review questions and answers. The chapter-based approach facilitates use with course notes or larger texts.

Valuable learning aids include:

  • Short discussion of the major concepts that underlie basic principles or specific drug groups in every chapter
  • Explanatory figures and tables (many in full color) •
  • Review questions followed by answers and explanations
  • Overview diagrams visually organize drug groups and concepts
  • A list of high-yield terms and definitions you need to know
  • Skill Keeper Questions prompt you to review previous material to understand links between related topics
  • A checklist of tasks you should be able to perform upon completion of each chapter
  • Summary tables that list the important drugs and include key information about their mechanisms of action and effects, clinical uses, pharmacokinetics, drug interactions, and toxicities
  • Two comprehensive 100-question examinations followed by the answer keys and explanations for the correct answers
  • An appendix describing test-taking strategies for improving your test performance
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Apr 212017
 

Gastrointestinal Pharmacology (Handbook of Experimental Pharmacology)


This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.

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Apr 212017
 

Toxicology and Clinical Pharmacology of Herbal Products (Forensic Science and Medicine)


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By (author): Melanie Johns Cupp

The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Herbai remedies are for sale not just in health food stores, but in supermar­ kets, drug stores, and even discount warehouses. Along with the proliferation in sales has come a proliferation ofinformation sources. Not all ofthe sources are equally reliable, or even intelligible. Traditional herbalists c1assify thistle and mugwort as “cholagogues,” substances used to make the gallbladder con­ tract and release bile. Medical school graduates are unlikely to have ever heard the term, or even accept the notion that most right-sided abdominal pain is a result of diminished bile flow. Heroin and cocaine may not be the only drugs to come from plants, but a practicing physician or toxicologist might be forgiven for thinking so. In 1998, 1264 papers were published about cocaine and only 17 about kava kava, an abused herb that is not without toxic side effects. Unfortunately, the majority of the papers about kava kava were published in journals not found in ordi­ nary hospitallibraries. In recognition ofthis fact, and ofthe obvious need for a reliable reference work on herbai toxicology, The Toxicology and Clinical Pharmacology 0/ Herbal Products was an early addition to our new series in Forensie Science and Medicine. It is very badly needed.
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Apr 202017
 

Gendering Drugs: Feminist Studies of Pharmaceuticals


This book, by bringing together critical pharmaceutical studies and feminist technoscience studies, explores the way drugs produce sexed and/or gendered identities for those who take – or resist – them, and how feminist technoscience studies can contribute a theoretical lens with which to observe sex and gender in the pharmaceuticalization processes. Topics explored in this diverse collection include the use of hormones to delay puberty onset for trans children; HPV vaccination against cervical cancer in Sweden, the UK, Austria and Colombia; Alzheimer’s discourses; and the medication of prostate issues. Ericka Johnson has brought together an innovative and timely collection that demonstrates gender as relevant in studies of pharmaceuticals, and provides multiple examples of methodological and theoretical tools to consider gender while studying drugs.

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Apr 172017
 

Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches (AAPS Advances in the Pharmaceutical Sciences Series)


The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.     ?
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Apr 132017
 

The Pharmacist’s Guide to Evidence-Based Medicine for Clinical Decision Making


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While most practicing pharmacists are familiar with the term and the general concept of evidence-based medicine, few are adequately trained in the clinical application of these skills. Developed to give clinical pharmacists an edge, this book provides a practical approach for applying sound EBM principles to your clinical decision making process.

Decision making based on personal experience alone, without knowledge from well-designed, controlled, randomized trials with adequate sample size, often overestimates the efficacy and underestimates the safety risks associated with drugs. This book provides a roadmap that is instructional and, most importantly, practical for the pharmacist so these new skills can be applied immediately in practice.

Based on a five-step process perfected over ten years at the University of Missouri, Kansas City, School of Pharmacy, this exciting new approach will:

·         Reduce complexity

·         Shorten time for decision making support

·         Maintain rigor

·         Categorize quality of the evidence in a simple, straightforward, and logical manner

·         Provide a process designed specifically for pharmacists making drug therapy decisions

Use of examples, tables, diagrams, and key points highlighted throughout the book and summarized at the end of each chapter provide the pharmacist with skills they can implement the next day to begin applying EBM principles to their practice. 

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Apr 092017
 

Diabetic Retinopathy: Current Pharmacologic Treatment and Emerging Strategies


By (author): Michael W. Stewart

A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. 

Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option.

Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.

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Apr 062017
 

Sample Preparation of Pharmaceutical Dosage Forms: Challenges and Strategies for Sample Preparation and Extraction


This book is intended to serve as a resource for analysts in developing and troubleshooting sample preparation methods.  These are critical activities in providing accurate and reliable data throughout the lifecycle of a drug product. 

This book is divided into four parts:

•          Part One covers dosage form and diluent properties that impact sample preparation of pharmaceutical dosage forms and the importance of sampling considerations in generating data representative of the drug product batch. 

•          Part Two reviews specific sample preparation techniques typically used with pharmaceutical dosage forms.

•          Part Three discusses sample preparation method development for different types of dosage forms including addressing drug excipient interactions and post extraction considerations, as well as method validation and applying Quality by Design (QbD) principles to sample preparation methods.  

•          Part Four examines additional topics in sample preparation including automation, investigating aberrant potency results, green chemistry considerations for sample preparation and the ideal case where no sample preparation is required for sample analysis.

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Apr 052017
 

Testosterone: From Basic to Clinical Aspects


Research on testosterone is increasing in many senses; however there is still much controversy regarding its physiology and clinical use. This book addresses these topics, providing a broad over­view about testosterone, from its basic fea­tures to the most recent evidence of clin­ical applicability. Also, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. Although not essential for survival, testosterone represents the essence of male biological function, being the important testicular androgen in men. Low serum testosterone levels are asso­ciated with cardiovascular morbidity, meta­bolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Conversely, increased serum levels of testosterone may lead to deleteri­ous events. In general, there is increasing evidence that serum testosterone is a major biomarker status of men’s health in general.

Testosterone: From Basic to Clinical Aspects is an indispensable reference for all those who seek state-of-the-art knowledge regarding this hormone, from basic issues (including pharma­cology and physiology) through clinical aspects (related diseases and supplementation ther­apy).

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