Pharmacology for Women’s Health

 Pharmacology  Comments Off on Pharmacology for Women’s Health
Apr 172019
 

Each new print copy includes Navigate 2 Advantage Access that unlocks a comprehensive and interactive eBook, student practice activities and assessments, a full suite of instructor resources, and learning analytics reporting tools. Navigate 2 will be available in December 2015. In the meantime, we invite you to redeem your Access Code and join our Lounge. Once your Navigate 2 Advantage Access is live, we will notify you via email. Pharmacology for Women s Health, Second Edition is a unique text that discusses pharmacology as it specifically relates to women s health. Completely updated and revised to reflect the changing field of pharmacology, it includes new pharmacological agents for common conditions, changes in indications, the use of vaccines, updated guidelines from the Centers for Disease Control and Prevention (CDC) for treatment of sexually transmitted infections, and the effects of the Affordable Care Act. It also includes new resource boxes in each chapter for easy access to more information.

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Polypharmacology in Drug Discovery

 Pharmacology  Comments Off on Polypharmacology in Drug Discovery
Apr 152019
 

An essential outline of the main facets of polypharmacology in drug discovery research

Extending drug discovery opportunities beyond the “one drug, one target” philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more. Filled with a collection of instructive case studies that reinforce the material and illuminate the subject, this practical guide:

• Covers the two-sided nature of polypharmacology—its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes
• Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles
• Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology
• Fosters interdisciplinary drug discovery research by embracing computational, synthetic, in vitro and in vivo pharmacological and clinical aspects of polypharmacology
A clear road map for helping readers successfully navigate around the problems involved with promiscuous ligands and targets, Polypharmacology in Drug Discovery provides real examples, in-depth explanations and discussions, and detailed reviews and opinions to spark inspiration for new drug discoveryprojects.

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Pharmacoepidemiology

 Epidemiology, Pharmacology  Comments Off on Pharmacoepidemiology
Apr 142019
 

Now in its fifth edition, Pharmacoepidemiology defines the discipline and provides the most comprehensive guidance of any book on the topic. Written by world renowned experts in the field, this valuable text surveys the research designs and sources of data available for pharmacoepidemiologic research, and provides descriptions of various automated data systems, along with the advantages and disadvantages of each.
Incorporating perspectives from academia, industry and regulatory agencies, this book provides detailed insights into all aspects of pharmacoepidemiology.

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Analysis of Aggregates and Particles in Protein Pharmaceuticals

 Pharmacology  Comments Off on Analysis of Aggregates and Particles in Protein Pharmaceuticals
Apr 132019
 

This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.

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Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition

 Geriatrics, Pharmacology  Comments Off on Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition
Apr 132019
 



In this era of increased pharmaceutical industry competition, success for generic drug companies is dependent on their ability to manufacture therapeutic-equivalent drug products in an economical and timely manner, while also being cognizant of patent infringement and other legal and regulatory concerns.

Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition presents in-depth discussions from more than 30 noted specialists describing the development of generic drug products—from the raw materials to the development of a therapeutic-equivalent drug product to regulatory approval.

Major topics discussed include:

Active pharmaceutical ingredients
Experimental formulation development, including a new section on Quality by Design (QbD)
Scale-up
Commercial product formulation
Quality control and bioequivalence
Drug product performance
ANDA regulatory process
Post-approval changes
Post-marketing surveillance
Legislative and patent challenges

This second edition also contains a new chapter on the relationship between the FDA and the United States Pharmacopeia and in Chapter 4, using specific examples, the application of Quality by Design (QbD) during formulation development is examined.The book is a thorough guide to the development of solid oral generic dosage formulations. This textbook is ideal for the pharmaceutical industry, graduate programs in pharmaceutical sciences, and health professionals working in the area of generic drug development.

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Molecular Pharmacology: From DNA to Drug Discovery

 Pharmacology  Comments Off on Molecular Pharmacology: From DNA to Drug Discovery
Apr 072019
 

This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body.

Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments.

Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell.

• Current – focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data.
• Cutting Edge – highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects.
• Applied – includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect.
• Accessible – contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.

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Essentials of Human Physiology and Pathophysiology for Pharmacy and Allied Health

 Pathology, Pharmacology, Physiology  Comments Off on Essentials of Human Physiology and Pathophysiology for Pharmacy and Allied Health
Mar 312019
 

Combining two separate textbooks entitled Essentials of Human Physiology for Pharmacy and Essentials of Pathophysiology for Pharmacy into one cohesive volume, this new book seamlessly integrates material related to normal human physiology and pathophysiology into each chapter.

Chapters include:

– Study objectives at the beginning of each chapter;
– Summary tables, flow charts, diagrams, and key definitions;
– Real life case studies to emphasize clinical application and stimulate student critical thinking;
– An emphasis on the rationale for drug therapy;
– Simple, straightforward language.

Written by authors with extensive teaching experience in the areas, Essentials of Human Physiology and Pathophysiology for Pharmacy and Allied Health is a concise learning instrument that will guide students in pharmacy and allied health programs.

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Pharmacotherapy Principles and Practice, Second Edition

 Pharmacology  Comments Off on Pharmacotherapy Principles and Practice, Second Edition
Mar 312019
 

Learn the Essential Principles of Pharmacotherapy and Understand Their Clinical Application
Now in full color!
Pharmacotherapy Principles and Practices utilizes a solid, evidence-based approach that supports the optimal pharmacotherapy of disease. In order to be as clinically relevant as possible, the disease states and treatments discussed focus on disorders most often seen in practice.

98 diseaes-based chapters review etiology, epidemiology, pathophysiology, and clinical presentation, followed by clear therapeutic recommendations for drug selection, dosing, and patient monitoring. All chapters have been written by content experts and reviewed by authorities in their fields.

Features:
NEW full-color format
NEW chapters on pediatrics, geriatrics, and palliative care
Valuable learning aids, including
Structured learning objects
Key concepts
Patient care and monitoring guidelines
Up-to-date literature citations
Tables, figures, text boxes, and algorithms
A glossary of terms
An online learning center that includes self-assessment questions and answers
Laboratory values expressed as both conventional units and SI units
Appendices that include conversion factors and anthropometrics, common laboratory tests and their reference ranges, and common medical abbreviations
Patient encounter vignettes to develop critical-thinking skills and make the text more applicable to everyday patient care

5 STAR DOODY’S REVIEW!
“This book covers more than 100 disease states using an easy-to-use format that includes structured learning objectives, key concepts, patient care and monitoring guidelines, up-to-date literature citations, tables, figures, text boxes, algorithms, a glossary of terms, and an online learning center….Although primarily for students, the book offers a concise review for general practitioners. There are more than 160 authors and 140 reviewers that contributed to this book and they represent the highest authority in the field.”–Doody’s Review Service

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Integrated Pharmaceutics: Applied Preformulation, Product Design, and Regulatory Science

 Pharmacology  Comments Off on Integrated Pharmaceutics: Applied Preformulation, Product Design, and Regulatory Science
Mar 302019
 

Focusing on the application of physical pharmacy, drug design, and drug regulations as they relate to produce effective dosage forms for drug delivery, Integrated Pharmaceutics provides a comprehensive picture of pharmaceutical product design, describing the science and art behind the concepts of dosage form development. Combining physical pharmacy, product design, and regulatory affairs issues in a single book, the authors address topics governing drug regulations of United States, European, and Japanese agencies and detail new regulatory guidelines, including quality by design, design space analysis, and blend sample uniformity.

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Neuropsychopharmacology and Therapeutics

 Neurology/Neurosurgery, Pharmacology  Comments Off on Neuropsychopharmacology and Therapeutics
Mar 182019
 

Neuropsychopharmacology is a relatively new subject area in the neurosciences. It is a field of study that describes the effects of drugs from the molecular to the behavioural level and requires integration and synthesis of knowledge from various disciplines including neuroanatomy, physiology, molecular biology, pharmacology and the behavioural sciences. The principal aims of this book are to provide students with a clear understanding of CNS disorders, and an appreciation of how basic and clinical research findings can be translated into therapeutics.

After an introduction to the subject area, the remaining chapters are focused on reviewing the main psychiatric and neurological disorders that are covered in most courses. They are discussed in terms of their clinical symptoms, epidemiology, pathology, aetiology, underlying neurobiological and neurochemical mechanisms, pharmacotherapy, adjunctive non–pharmacological treatments, and clinical outcomes. Each chapter of the book is a stand–alone chapter and is written in a clear, accessible style.

Written by an author with many years teaching and research experience, this textbook will prove invaluable for students of pharmacology, pharmacy and the medical sciences needing a truly integrated introduction to this exciting field.

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