Jul 192017
 

Pharmaceutical Data Mining: Approaches and Applications for Drug Discovery


By (author): Konstantin V. Balakin

Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development

In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover:

  • A general overview of the discipline, from its foundations to contemporary industrial applications
  • Chemoinformatics-based applications
  • Bioinformatics-based applications
  • Data mining methods in clinical development
  • Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches

In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.

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Jul 152017
 

Chromatographic Fingerprint Analysis of Herbal Medicines Volume IV: Thin-Layer and High Performance Liquid Chromatography of Chinese Drugs


Volume IV of this manual provides an overview of the analytical investigation of numerous additional Chinese Herbal Drugs, which are most commonly used in Traditional Chinese Medicine (TCM). The detailed chromatographic analysis of the main compounds is illustrated in coloured TLC-photographs and HPLC-peak profiles. Further bioactive properties, pharmacological and biological activities of all single herbal drugs, as well as their therapeutic applications are discussed. Together with Volumes I – III this current volume represents the most comprehensive overview to analytical studies of those herbal drugs on the market and therefore serves as a must-have manual for researchers and laboratories dedicated to TCM. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority.  
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Jul 152017
 

Practical Child and Adolescent Psychopharmacology (Cambridge Child and Adolescent Psychiatry)


Features: Used Book in Good Condition

This important book synthesizes the most recent research findings pertaining to drug treatments of various psychiatric disorders in children, including attention-deficit hyperactivity disorder, obsessive-compulsive disorder, major depression, schizophrenia, bipolar mania, aggression in pervasive developmental disorder, Tourette’s syndrome, and substance abuse. The chapters examine the issues of tolerability and efficacy, and inappropriate over-use, within a social and developmental context. For each disorder, pharmacotherapy is discussed in the wider context of neurobiology, etiology, diagnosis, and treatment.
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Jul 152017
 

Chromatographic Fingerprint Analysis of Herbal Medicines Volume III: Thin-layer and High Performance Liquid Chromatography of Chinese Drugs


Volume III of this manual provides an overview of the analytical investigation of 23 additional Chinese Herbal Drugs, which are most commonly used in Traditional Chinese Medicine. Together with Volumes I and II this current volume represents the most comprehensive overview to analytical studies of those herbal drugs. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority. The authors refer to the bioactive constituents, pharmacological and biological activities of all single herbal drugs, as well as their therapeutic applications. Analytical methods applied are described in detail.
List Price: $189.00 USD
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Jul 152017
 

Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry


By (author): Jie Jack Li

For the world’s largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizer’s Lipitor, GlaxoSmithKline’s Advair, AstraZeneca’s Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb’s Plavix all came off patent in the crucial U.S. market. This so-called “patent cliff” meant hundreds of billions of dollars in lost revenue and has pharmaceutical developers scrambling to create new drugs and litigating to extend current patent protections.

Having spent most of his career in drug discovery in “big pharma,” Dr. Li now delivers an insider’s account of how the drug industry ascended to its plateau and explores the nature of the turmoil it faces in the coming years. He begins with a survey of the landscape before “blockbuster drugs,” and proceeds to describe how those drugs were discovered and subsequently became integral to the business models of large pharmaceutical companies. For example, in early 1980s, Tagamet, the first “blockbuster drug,” transformed a minor Philadelphia-based drug maker named SmithKline & French into the world’s ninth-largest pharmaceutical company in terms of sales. The project that delivered Tagamet was nearly terminated several times because research efforts begun in 1964 produced no apparent results within the first eleven years. Similar stories accompany the discovery and development of now-ubiquitous prescription drugs, among them Claritin, Prilosec, Nexium, Plavix, and Ambien.

These stories, and the facets of the pharmaceutical industry that they reveal, can teach us valuable lessons and reveal many crucial aspects about the future landscape of drug discovery. As always, Dr. Li writes in a readable style and intersperses fascinating stories of scientific discovery with engaging human drama.

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Jul 152017
 

Chromatographic Fingerprint Analysis of Herbal Medicines: Thin-layer and High Performance Liquid Chromatography of Chinese Drugs


This manual, to be published in two volumes, provides a condensed overview of the analytical investigation of 80 Chinese Herbal Drugs which are most frequently in use. Thin layer chromatographic-, high pressure liquid chromatographic- and gas chromatographic-fingerprint analytical techniques allow the detection of all main low-molecular constituents of a plant drug and even single constituents can be visualized. Analytical results thereof are shown in numerous color figures. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority.

Furthermore, this volume gives a detailed description of the analytical methods used for several drugs. Bioactive constituents, pharmacological and biological activities of several single herbal drugs as well as their therapeutic applications are discussed.

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Jul 142017
 

Prodrugs and Targeted Delivery: Towards Better ADME Properties, Volume 47


This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today’s drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
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Jul 142017
 

Orofacial Disorders: Current Therapies in Orofacial Pain and Oral Medicine


This cutting-edge book is a quick reference guide to the evidence-based evaluation, diagnosis, and management of the broad spectrum of orofacial disorders. Each chapter is devoted to a particular disease or disorder and presents advances in our understanding of the condition, the most recent evaluation and diagnostic strategies, and up-to-date treatment approaches. In addition, strategies for integration of care into routine dental practice are explained, and information provided on how to comprehensively diagnose and manage orofacial disorders. The coverage encompasses the latest technological advances in the field, such as novel pharmaceuticals, diagnostic tools, gene transfer techniques, radiotherapy modalities, and a vast array of interdisciplinary and multidisciplinary approaches including complementary and alternative therapies for orofacial disorders.Although the management of orofacial disorders is emerging as a distinct field of dentistry, many dentists and physicians are unfamiliar with recent advances in the care of patients with these disorders including orofacial pain, oral lesions and cancer, malodor, xerostomia, obstructive sleep apnea, bruxism and oral parafunctional behaviors, temporomandibular disorders, occlusal dysesthesias, orofacial neuropathic pains, and headaches. This book, written by world class experts, is deliberately geared to the level of understanding of a clinician. It will serve as an ideal evidence-based reference and source of specific clinical recommendations in daily practice.

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Jul 132017
 

Pharmacology Success: A Q&A Review Applying Critical Thinking to Test Taking ( Second Edition ) (Davis’s Q&a Success)


By (author): Ray A. Hargrove-Huttel RN PhD, Kathryn Cadenhead Colgrove RN MSN CNS

#1 Best Seller in Clinical Pharmacology on Amazon!

Course review now. NCLEX-prep later. 1,000+ critical-thinking questions (both multiple choice and alternate format) organize the seemingly huge volume of pharmacology information you must master into manageable sections divided by body systems and specific diseases. You’ll not only learn to associate the medication with the disease process, making learning easier, but also be able to evaluate your knowledge before you take your exams.

All of the questions encompass the basic concepts of medication administration, including why the client is taking the medication…when the nurse would question administering the medication…how the nurse knows the medication is effective…and what interventions the nurse needs to teach the client concerning the medication.

 

 

See what students are saying about the Success Series…

Great book!“If you are taking pharmacology, you MUST get this book! It is amazing and helps prepare you for those critical thinking NCLEX style questions. Such a great buy, would recommend to ALL nursing students!”

—Samantha, Student Amazon Reviewer

A must-have for Nursing Pharmacology“This book is a must have for finishing nursing pharmacology! I wouldn’t had been able to finish the class without this book & I did receive an A. Great questions with clear and concise rationales. I prefer the FA Davis Success Series to any other NCLEX test-prep books out there.”

Nursing Student and Amazon Reviewer

“I love that the questions come with rationales and that the books are filled with relevant questions! Tons of people in my class use them and without fail we rave about them after each test!”

—Taryn Van Rensburg, Student Nurse, Naugatuck Valley Community College, CT.

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Jul 102017
 

McGraw-Hill’s 2016/2017 Top 300 Pharmacy Drug Cards


By (author): Jill M. Kolesar, Lee Vermeulen

The best and easiest way to learn essential information about the top 300 drugs

Includes recently approved hepatitis C vaccines

Every card includes:

  • Generic and common name
  • Class
  • Dosage Forms
  • Approved Dose and Indications
  • Off-Label Use
  • Contraindications
  • Adverse Reactions
  • Drug Interactions
  • Monitoring Parameters
  • Medication Safety Issues and Black Box Warnings
  • Clinical pearls that help guide patient care
  • Strong focus on patient safety

This edition is enhanced by 11 new cards, key adult and pediatric immunization vaccines, and MP3 audio download with detailed discussion of each drug.

List Price: $60.00 USD
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