May 022016
 

Biological Effects of Metal Nanoparticles


By (author): Elena Mikhailovna Egorova, Aslan Amirkhanovich Kubatiev, Vitaly Ivanovich Schvets

This book offers a comprehensive overview of recent studies conducted on the biological effects of metal nanoparticles. It also provides a solid theoretical foundation and various metal nanoparticle synthesis methods.

Part I reviews the main chemical methods used for synthesizing metal nanoparticles in a solution and describes original method of biochemical synthesis, as well as some special procedures developed specifically for studying the biological activity of nanoparticles.

Part II analyzes current literature on the effects of metal nanoparticles observed in microorganisms and addresses the influence of silver nanoparticles obtained by biochemical synthesis on biological objects on various organization levels, namely on microorganisms,  acellular slim mold, unicellular alga, plant seeds  and mammalian cells.

The last section explains the central problems common in studies on the biological effects of metal nanoparticles and outlines potential uses of this trend in bio-nanotechnologies.

This book is aimed at specialists, professors and students aspiring to expand their knowledge about the biological activities of metal nanoparticles and nanoparticle-containing materials.

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May 012016
 

Shooting Up: A Short History of Drugs and War


By (author): Lukasz Kamienski

Shooting Up: A Short History of Drugs and War examines how intoxicants have been put to the service of states, empires and their armies throughout history. Since the beginning of organized combat, armed forces have prescribed drugs to their members for two general purposes: to enhance performance during combat and to counter the trauma of killing and witnessing violence after it is over. Stimulants (e.g. alcohol, cocaine, and amphetamines) have been used to temporarily create better soldiers by that improving stamina, overcoming sleeplessness, eliminating fatigue, and increasing fighting spirit. Downers (e.g. alcohol, opiates, morphine, heroin, marijuana, barbiturates) have also been useful in dealing with the soldier’s greatest enemy – shattered nerves. Kamienski’s focuses on drugs “prescribed” by military authorities, but also documents the widespread unauthorised consumption by soldiers themselves. Combatants have always treated with various drugs and alcohol, mainly for recreational use and as a reward to themselves for enduring the constant tension of preparing for. Although not officially approved, such “self-medication” is often been quietly tolerated by commanders in so far as it did not affect combat effectiveness. This volume spans the history of combat from the use of opium, coca, and mushrooms in pre-modern warfare to the efforts of modern militaries, during the Cold War in particular, to design psychochemical offensive weapons that can be used to incapacitate rather than to kill the enemy. Along the way, Kamienski provides fascinating coverage of on the European adoption of hashish during Napolean’s invasion of Egypt, opium use during the American Civil War, amphetamines in the Third Reich, and the use of narcotics to control child soldiers in the rebel militias of contemporary Africa.
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Apr 302016
 

Apoptosis Methods in Toxicology (Methods in Pharmacology and Toxicology)


This detailed volume provides a single, valuable reference source for methods that definitively identify and accurately quantify apoptosis. The book begins with common methods utilized to detect and quantitate apoptosis, as well as apoptosis signaling pathways in toxicological and other related research. It continues with multi-parametric and phased apoptosis assays for detecting early and late apoptosis or distinguishing apoptosis from necrosis and autophagy. Subsequent chapters focus on recent advances in real time and high-throughput assays that detect and quantitate apoptosis and apoptosis signaling pathways. Final chapters focus on recent developments in preclinical anticancer therapeutics targeting apoptosis. Written for the Methods in Pharmacology and Toxicology series, chapters feature step-by-step descriptions of the methodologies, as well as expert tips and implementation advice.

Vital and authoritative, Apoptosis Methods in Toxicology serves novice scientists as well as experts, utilizing a range of instruments from common laboratory equipment to high-end expensive and automated machinery capable of performing real time apoptotic measurements.

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Apr 292016
 

Antibiotic Pharmacodynamics (Methods in Pharmacology and Toxicology)


This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation.  The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab.

Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.

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Apr 282016
 

Translational Toxicology: Defining a New Therapeutic Discipline (Molecular and Integrative Toxicology)


Bringing together a distinguished interdisciplinary team of contributors,this volume provides a comprehensive exploration of translational toxicology?a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures.In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice.

Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.

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Apr 272016
 

Case Files: Pharmacology, 2nd Edition


Features: ISBN13: 9780071488587, Condition: New, Notes: BRAND NEW FROM PUBLISHER! 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!
By (author): Eugene Toy, Gary Rosenfeld, David Loose, Donald Briscoe

Real Life Clinical Cases for the Basic Sciences and USMLE Step 1

You need exposure to clinical cases to pass course exams and ace the USMLE Step 1. Case Files: Pharmacology presents 53 real-life clinical cases that illustrate essential concepts in pharmacology. Each case includes an easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, pharmacology pearls, and USMLE-style review questions. With this interactive system, you’ll learn instead of memorize.

This second edition gives you:

  • 53 clinical cases, each with USMLE-style questions
  • Clinical pearls that highlight key concepts
  • Primer on how to approach clinical problems
  • Proven learning system that improves your shelf exam scores

    Here’s what students have to say:

    “The Case Files books have continued to help me in preparation for my case-based exames tremendously! I can honestly sasy they played a major role in my success this year and are becoming a great resource in the beginning of my board preparation.”–Joshua Lynch, Class of 2008, Lake Erie College of Osteopathic Medicine

    Case Files: Pharmacology focuses on rapid understanding of the whys and hows of drug use and prescription. This format allows for development of a knowledge base that will last long past the boards. Every medical student should use this book.”–Suzanne Crandall, Class of 2005, Kansas City University of Medicine and Biosciences, College of Osteopathic Medicine

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Apr 262016
 

New Approaches to Drug Discovery (Handbook of Experimental Pharmacology)


This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies to identify biologics as leads are addressed. The final part focuses on the pharmacological models and technologies to characterize new compounds and the impact of biomarkers to facilitate the transfer of drug candidates into the development phase.

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Apr 262016
 

Stimuli Responsive Drug Delivery Systems: From Introduction to Application


By (author): Anil Bajpai

Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The polymer architectures exhibiting a large change in their physico chemical behaviors in response to minor signals from the environments have fabricated potentially useful materials for pharmaceutical and biomedical applications. The most advanced stimuli responsive drug delivery systems have also explored a new strategy to design targeted delivery systems to treat complex diseases like cancers and related tumors. Stimuli Responsive Drug Delivery Systems offers a convincing approach to understanding the basic principles of drug delivery process, their mathematical modeling, different types of drug delivery systems, various polymer systems responsive to stimuli such as swelling, pH, temperature, electric and magnetic fields, chemical agents, and more. The material covered in this books provides a wide spectrum of information – academic, research, and professional – for the biomedical, pharmaceutical and polymer chemistry communities. The book also presents the commercial scenario of drug delivery systems and highlights upcoming challenges and existing future prospects of this field. An exhaustive bibliography of the book also enables students and researchers of various disciplines to acquire additional information they may require.
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Apr 252016
 

The Healing of America: A Global Quest for Better, Cheaper, and Fairer Health Care


Features: Health care, T.R. Reid, America, Medical, Cheaper
By (author): T. R. Reid

A New York Times Bestseller
With an Explanation of the 2010 Health Reform Bill

Bringing to bear his talent for explaining complex issues in a clear, engaging way, New York Times bestselling author T. R. Reid visits industrialized democracies around the world–France, Britain, Germany, Japan, and beyond–to provide a revelatory tour of successful, affordable universal health care systems. Now updated with new statistics and a plain-English explanation of the 2010 health care reform bill, The Healing of America is required reading for all those hoping to understand the state of health care in our country, and around the world.

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Apr 232016
 

Prescription Drug Abuse: A Reference Handbook (Contemporary World Issues)


By (author): David E. Newton Ph.D.

This outstanding resource guide for students and young adults provides an introduction to the history of prescription drug abuse that explains how this problem has arisen and examines the social, political, economic, and health issues associated with prescription drug abuse in modern society.

• Explains the dangers associated with the use of prescription drugs for nonmedical purposes

• Provides a detailed introduction for readers seeking to learn about the topic of prescription drug abuse and serves as an research tool for school projects

• Includes thought-provoking perspective essays from individuals involved in the discussion of how to address prescription drug abuse

• Supplies primary source documents in the form of excerpts from laws, administrative rulings, and court cases regarding prescription drug abuse as well as a glossary of key terms used in discussing the topic of prescription drug abuse

List Price: $60.00 USD
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