Nov 112014
 


Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
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Oct 302014
 


The BNF for Children (BNFC) provides essential practical information to all healthcare professionals involved in the prescribing, dispensing, monitoring and administration of medicines to children.
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Oct 262014
 


Packed with the latest data, the powerful new Seventh Edition of Howard Abadinsky's DRUG USE AND ABUSE: A COMPREHENSIVE INTRODUCTION delivers a thorough, interdisciplinary survey of all aspects of drug and alcohol abuse. The text draws from the many disciplines of history, law, pharmacology, political science, social work, counseling, psychology, sociology, and criminal justice -- resulting in the most comprehensive, authoritative resource available. Coverage includes the history of drugs, their impact on society, the pharmacological impact of drugs on the body, drug policy implications, the criminal justice system response, the drug business, law enforcement, theories of use, as well as the effects, treatment, and prevention of abuse.
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Oct 222014
 


This handy, portable book provides information on potential adverse effects when prescribing two or more drugs for simultaneous use, organised by drug class in a convenient, user-friendly format. Interactions that are likely to give rise to life-threatening conditions and which must therefore be completely avoided are clearly highlighted. Less threatening, but nonetheless important, interactions necessitating practical measures such as frequent monitoring and advice to patients are also detailed.

Presented in tabular form for ease of reference, the book also provides a brief summary of the mechanism underlying a particular interaction, alternative drugs lacking the same reactions that may be considered, and instructions for monitoring patients when adverse affects occur.

This book is an essential companion for the physician, nurse prescriber and pharmacist in the clinical setting and an invaluable reference for medical students.

  • Portable guide covering all major drug groups
  • At-a-glance tabular format
  • Use of complex pharmacological terminology minimised for the non-specialist
  • All advice supported by appropriate evidence
  • Also includes potential interactions with over the counter medications, herbal remedies, dietary supplements, food, and alcohol
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Oct 102014
 


This second edition of a global best-seller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (QbD) concept in pharmaceutical manufacturing.
As in the first edition, the analytical requirements during the entire product lifecycle are covered, but now a new section is included on continued performance monitoring and the transfer of analytical procedures. Two case studies from the pharmaceutical industry illustrate the concepts and guidelines presented, and the standards and regulations from the US (FDA), European (EMA) and global (ICH) regulatory authorities are considered throughout.
The undisputed gold standard in the field.
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Oct 052014
 


“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013



The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients.

This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover:

• Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models
• Effect of genetic differences and non-genetic factors on drug metabolism
• Balance among drug metabolism, its inactivation/activation, and its potential toxicity
• Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans
• Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions

This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians.

Enjoy the Online Advantage...
The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov

 

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Oct 042014
 


From Abilify to Zyrtec and nearly every drug in between, Mosby's Drug Reference for Health Professions, 4th Edition is the must-have portable drug handbook for every current or aspiring health professional in the field today. This updated edition features concise, reliable information that is easy to navigate, with alphabetically listed monographs for over 900 generic drugs (including 4,500 trade-name drugs, for both US and Canada).

  • Precautions and Considerations sections address key storage and administration details appropriate for a wide variety of health professions.
  • Abbreviated drug monographs organized alphabetically by generic name save you time finding need-to-know details for day-to-day practice.
  • Special drug information icons call your attention to important information necessary in emergency situations when a quick answer is critical.
  • Two-color design formathighlights key elements and information for quick and easy access.
  • Lifespan content equips you with the answers you need when working with the elderly, pediatric and adult populations health professionals encounter.
  • Drug storage information arms health professionals with information about the extra care necessary to maintain drug potency.
  • NEW! A thoroughly reviewed and clinically accurate drug list that health professionals, practitioners and students can rely on.
  • NEW! E-book version has pill images from the website integrated into corresponding monographs.
  • NEW! English to Spanish drug phrases translator available on companion website.
  • NEW! 45 new monographs! Over 900 drug monographs in total supply you with the most current and inclusive drug information.
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Sep 292014
 

Antibiotics Simplified (Paperback)

By (author): Jason C. Gallagher, Conan MacDougall

#5 of the Top 10 Bestsellers at the ACCP Bookstore (Updates in Therapeutics® Conference, Reno, NV, May 2012) Doody's Review Service, Rating: 98 - 5 Stars! See the Reviews tab for additional comments and testimonials. Antibiotics Simplified, Second Edition is a succinct guide designed to bridge knowledge gained in basic sciences courses with clinical practice in infectious diseases. This practical text reviews basic microbiology and how to approach the pharmacotherapy of a patient with a presumed infection. It also contains concise Drug Class Reviews with an explanation of the characteristics of various classes of antibacterial drugs and antifungal drugs. New to the Second Edition • Expanded coverage of drug classes • Antiviral agents (antiretrovirals for HIV, anti-mycobacterial, and anti-parasitic agents) • New appendix including empiric regimens for common infections • 17 new chapters in total Each Drug Class Review Includes • Agents Belonging to Each Class • Drugs Used Most Commonly in Practice • Spectrum of Activity • Adverse Effects • Dosing Issues • Important Points • Useful Indications Instructor Resources: Image Bank and Test Bank Antibiotics Simplified, Second Edition simplifies learning infectious disease pharmacotherapy and condenses the many facts that are taught about antibiotics into one quick reference guide. This guide will help students learn the characteristics of antibiotics and why an antibiotic is useful for an indication. With an understanding of the characteristics of the antibiotics, students will be able to make a logical choice to treat an infection more easily. With helpful figures and flow charts, Drug Class Reviews, a Spectra of Activity chart, and an index for reference, this is an ideal handbook for students as well as practicing pharmacists, physicians, and other clinicians!
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Sep 292014
 


Now in its Fourth Edition, Dosage Calculations Made Incredibly Easy! contains everything health care practitioners need to review and students need to learn about calculating drug dosages. This entertaining and informative reference reviews the basic math needed to perform dosage calculation, including fractions, decimals, percentages, ratios, and proportions. It walks the nurse through the interpretation of hundreds of examples of drug orders and the performance of hundreds of complex dosage calculations, and provides information on deciphering difficult abbreviations, dealing with unclear handwriting, reading medication labels, selecting administration equipment, and more. Special elements found throughout the book make it easy to remember key points.

Purchasers of this edition will also have access to the newest information on drugs at www.edruginfo.com.

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Sep 252014
 


Find the drug information you need fast! Trusted by nurses for over 25 years, Mosby's 2015 Nursing Drug Reference features a full-color design and convenient A-to-Z organization that offer quick and easy access to the latest and most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled and updated in drug monograph format - including 20 new drugs recently approved by the FDA. And no other drug handbook places a higher emphasis on patient safety, with Black Box Warnings for dangerous or life-threatening adverse reactions, Safety Alert icons for situations requiring special attention, and highlighted Common and Life-Threatening Side Effects. Comprehensive coverage also includes IV drugdosage and administration instructions, including special considerations and Y-site, syringe, and additive compatibilities. The companion Evolve website offers even more helpful features, such as additional drug monographs (including infrequently used or recently approved drugs); guidelines to safe handling of chemotherapeutic agents; combination products; controlled-substance chart; drug name safety; drugs metabolized by known P450s; drugs to use cautiously for geriatric patients; herbal products; patient teaching guides in English and Spanish; and Canadian resources.

  • More than 5,000 generic and trade-name drugs are profiled, covering almost every drug you will administer in practice or in clinicals.
  • Attractive full-color design highlights important information for quick and easy access.
  • Black Box Warnings provide alerts to dangerous or life-threatening adverse reactions.
  • Safety Alert icon identifies situations that require special attention.
  • Common and life-threatening side effects are organized by body system, showing signs to watch for during assessments.
  • Nursing Process steps are used as the framework for organizing all nursing care information.
  • Coverage of IV drug administration highlights dosage and IV administration instructions, including special considerations and Y-site, syringe, and additive compatibilities.
  • Comprehensive drug monographs include generic names, Rx or OTC availability, pronunciations, U.S. and Canadian trade names, functional and chemical classification, controlled-substance schedule, do-not-confuse drugs, action, uses, unlabeled uses, dosages and routes, available forms, side effects, contraindications, precautions, pharmacokinetics, interactions (including drug/herb, drug/food and drug lab test), nursing considerations, and treatment of overdose.
  • Complete pharmacokinetic information includes the mechanism and absorption of the drug as well as its action, duration, and excretion.
  • Flexible, water-resistant cover provides durability in the clinical setting.
  • A companion website includes updates with infrequently used or recently approved drugs, a full-color pill atlas, guidelines to safe handling of chemotherapeutic agents, combination products, drugs metabolized by known P450s, medications to be cautiously for geriatric patients, herbal products, a listing of high-alert Canadian medications and immunization schedules, patient teaching guides in English and Spanish, and more.
  • 20NEWmonographs provide current content on added or newly released drugs.
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