Jul 222017
 

Oxygen Transport to Tissue XXXIX (Advances in Experimental Medicine and Biology)


This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles.  Both overview and the most recent, advanced techniques for oxygen measurement are presented.   Articles and peer reviewers include those from leaders in their field.  Topics such as molecular signaling in the organismal and tumor response to low levels of local oxygenation, hypoxia inducible factor (HIF) , cancer metabolism, individual human and animal response to oxygen changes monitored by optical/near infrared spectroscopy/ tomography to novel electron resonance spectroscopy and spectroscopic imaging, instrumentation, progress in blood substitute research, retinal physiology, cellular hypoxia, mitochondrial function; brain oxygenation and function;  oxygen transport in sports, hypoxia in diseases and clinical care.

Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.

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Jul 152017
 

Managing BRCA Mutation Carriers


As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.
Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
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Jul 142017
 

Healing Collective Trauma Using Sociodrama and Drama Therapy


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By (author): Eva Leveton MS MFC

Psychodrama and Socio-drama are new concepts of therapy to resolve mental health issues in Bangladesh. Mental health professionals in Bangladesh who had been able to absorb the technique created by integrating socio-psychodrama have been greatly benefited from this intervention in the healing process… ”

Mehtab Khanam, PhD
Professor of Psychology
Dhaka University
Bangladesh

When large groups of people become victims of political upheavals, social crises, and natural disasters, it is often challenging to allocate appropriate resources to deal with the stress that ensues. Of the methods employed to address post-traumatic stress syndrome and collective trauma, sociodrama and drama therapy have had a long-standing history of success. Group therapists and counselors will find this book to be an indispensable resource when counseling patients from trauma-stricken groups.

This book travels across geographic and cultural boundaries, examining group crises and collective trauma in Asia, Africa, Europe, and the U.S. The contributing authors, many of whom are pioneers in the field, offer cost-effective, small- and large-group approaches for people suffering from PTSD, socio-political oppression, and other social problems. The book extends the principles and practices of psychodrama and sociodrama to include music, painting, dance, collage, and ritual. In essence, this innovative book illustrates the proven effectiveness of sociodrama and drama therapy. Key topics:

  • The difficulties of developing trust in victimized or opposing groups
  • Initiating warm-ups and therapeutic strategies with both groups and individuals
  • Narradrama” with marginalized groups
  • Using anti-oppression models to inform psychodrama
  • Re-reconciling culture-based conflicts using “culture-drama”
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Jul 092017
 

Alcoholism: Its Treatments and Mistreatments


By (author): Irving Maltzman

This important book provides a review of the Minnesota Model of alcoholism treatment, which combines current clinical treatments and the 12-step principles of Alcoholics Anonymous with the goal of abstinence. It critically examines the research base supporting cognitive behavior therapy approaches to alcoholism. Using evidence from biosociobehavioral science and critical analyses of alcoholism treatment outcome literature, the book rebuts the view of cognitive behavior therapists that alcoholism is nothing but a bad habit .

This book fills a vital need, describing which alcoholism treatments work and which do not. It is an invaluable guide to the helping professions caring for alcoholics, alcoholism counselors, social workers, nurses, clinical psychologists and psychiatrists as well as the intelligent layperson interested in alcoholism and its treatment. It also serves as a textbook for alcoholism courses and as an ancillary text for abnormal psychology courses.

Contents: A Biosociobehavioral Disease Conception of Alcoholism; Alcoholism Treatments and Mistreatments; What Makes Alcoholics Anonymous Work; Expectancy Theory and Research: Balderdash; Self-selection of Alcoholism Treatment Goals: Harm Reduction or Induction; Little Albert Redux II: Bias and Lack of Scholarship in Textbooks; Sociology of Science and Alcoholism Studies.

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Jul 082017
 

State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 1.: Monoclonal Antibody Therapeutics: … and Regulatory Space (ACS Symposium Series)


Monoclonal antibodies (mAbs) are an important class of therapeutic that has greatly expanded our ability to treat a variety of indications, including cancer, autoimmune disorders, and infectious diseases. The cost of developing these molecules and ensuring that they are fit for purpose is much higher than for small-molecule drugs. Although some of these costs are due in part to the nature of production, a major cost is incurred because of the complexity of the molecule itself. Extensive analytical testing regimes are needed for in-depth characterization and to ensure product stability, proper in-process controls, safety, and efficacy. The next generation of product understanding will require highly complex, orthogonal technologies to elucidate interdependent structure-function relationships.

The ACS’ focus on this field of research represents a defining moment in the development of technologies for characterizing mAbs. A multitude of experts in the field have come together around a single molecule for the first time to demonstrate both current and future practices involved in the characterization of a biotherapeutic. The current series presents an open discussion of current best practices, a multitude of intuitive research, and a collaborative philosophy on where the field needs to move to satisfy future scientific and regulatory needs. Throughout this effort, a first-of-a-kind repository of regulatory considerations, experimental methods, and data–as well as a widely available “reference”–are now available to industry, academia, regulatory personnel, and instrument manufacturers.

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Jul 062017
 

Preventing Chronic Diseases: A Vital Investment


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By (author): World Health Organization

This report dispels the long-held misunderstandings about heart disease, stroke, cancer and other chronic diseases that have contributed to their global neglect. The reality is that 80% of this year’s 35 million, chronic disease-related deaths will occur in low and middle income countries, where they affect men and women at younger ages than in high income countries. Premature deaths in countries such as China, India and the Russian Federation are projected to cost billions of dollars over the next 10 years.

Even more importantly, this report gives practical advice for reducing deaths and improving the lives of millions of people. Every country, regardless of its level of resources, has the potential to make significant improvements in chronic disease prevention and control. A great amount can be achieved with leadership and effective and low-cost interventions.

The primary audience of the report is health planners and decision-makers as well as stakeholders who can influence multisectoral government action.

Chronic diseases are a major global health problem and a key barrier to development, to alleviating poverty and to making progress towards the Millennium Development Goals. We know enough to act now. Cost-effective preventive and clinical interventions are available and need to be implemented globally. What we need are the resources to move from policy to action, and strong leadership from health ministries for coordinated national action.

– Dr LEE Jong-wook
World Health Organization

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Jun 222017
 

Handbook of Biomedical Nonlinear Optical Microscopy


The Handbook of Biomedical Nonlinear Optical Microscopy provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy for cell biologists, life scientists, biomedical engineers, and clinicians. The chapters are separated into basic and advanced sections, and provide both textual and graphical illustrations of all key concepts. The more basic sections are aimed at life scientists without advanced training in physics and mathematics, and tutorials are provided for the more challenging sections.

The first part of the Handbook introduces the historical context of nonlinear microscopy. The second part presents the nonlinear optical theory of two- and multiphoton excited fluorescence (TPE, MPE) spectroscopy, second and third harmonic generation (SHG, THG) spectroscopy, and coherent anti-Stokes Raman spectroscopy (CARS). The third part introduces modern microscopic and spectroscopic instrumentation and techniques that are based on nonlinear optics. The fourth part provides key applications of nonlinear microscopy to the biomedical area: neurobiology, immunology, tumor biology, developmental biology, dermatology, and cellular metabolism. There are also chapters on nonlinear molecular probes, cellular damage, and nanoprocessing.

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Jun 212017
 

Bedside Approach to Autonomic Disorders: A Clinical Tutor


Here is a practical reference for the everyday clinical management of ANS disorders. It features a problem-oriented approach to managing patients at the bedside and presents clinical cases to illustrate important syndromes.
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Release date June 30, 2017.

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Jun 172017
 

The Perils of Un-Coordinated Healthcare: A Strategic Approach toward Eliminating Preventable Harm


By (author): Patricia W Morrill

Despite its frequency and its potential severity, preventable medical harm is still prominent in American hospitals and continues to put an alarming amount of lives at risk, being the third leading cause of death in the United States. Even some of the most commonly performed surgeries, such as knee and hip replacements, are resulting in a rapidly increasing rate of surgical site infections.

Patricia Morrill’s book is specifically written for the healthcare industry. It fills the need for exposing how preventable harm is a systemwide problem and provides a step-by-step model to apply for raising process improvement to a strategic level. The approach is ideal for team training purposes. The Perils of Un-Coordinated Healthcare gives the reader both a personal and professional view of the impact of preventable medical harm, using case studies and observations on preventable deaths and healthcare practice alongside recommended research topics and resources. By looking at the work of both healthcare workers and their managing executives, this instructional text gives methods to assess workforces and self-assess the performances of managers. The book equips readers with a 360 view: patients, families, physicians, workforce, leaders and culture.

Morrill’s ten-step model of Process Improvement Strategy Deployment integrates Lean and Project Management methodologies for developing a problem-solving culture and initiating process improvement at a strategic level. It is essential reading for those in the healthcare industry.

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Jun 042017
 

Apoptosis: Modern Insights into Disease from Molecules to Man


Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced liver disease, chronic back pain, and cardiovascular health. With 40 chapters written by highly respected authorities, this single source reference provides researchers and scientists with the foundation they need.

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