Sep 262017
 

Pediatric Practice: Endocrinology, 2nd Edition


Features: Pediatric Practice Endocrinology 2nd Edition
By (author): Michael S. Kappy, David B. Allen, Mitchell E. Geffner

The go-to guide for managing endocrine problems in children – completely updated for today’s practice

Part of the Pediatric Practice series, Pediatric Practice: Endocrinology is an outstanding clinical analysis and decision-making tool for those treating endocrine problems in children. Featuring an innovative problem-oriented approach, this well-illustrated, full-color guide skillfully integrates pathophysiology with clinical management. Numerous figures illustrate the principles of normal and abnormal physiology and treatment rationale and effects.

Since an understanding of the clinical manifestations and treatments of endocrine disorders begins with knowledge of concepts of hormone action and principles of feedback control, the first chapter, “General Concepts and Physiology,” links genetics, cell biology, and physiology with pathophysiology to provide a clear and approachable overview of endocrine systems. Subsequent chapters discuss disorders of growth, puberty, thyroid and adrenal glands, sex development, calcium and bone metabolism, water homeostasis, and carbohydrate metabolism and its comorbidities.

In this second edition, contributing authors have updated all chapters. Important additions include sections on genetics for the endocrinologist in the general concepts chapter, an overview of the physiology and treatment of metabolic syndrome and dyslipidemia in the obesity chapter, and the addition of a new chapter on enteric hormones.

Features of the Pediatric Practice Series

The Pediatric Practice series simplifies the care of pediatric patients by delivering:

  • Tips that tell you what you must know–and what you must do–at every stage of care
  • Diagnostic and treatment algorithms
  • Signs/Symptoms and Differential Diagnosis boxes
  • When to Refer boxes, which examine all the relevant clinical considerations
  • Diagnostic Tests–with a realistic emphasis on the right tests to order
  • Medical Treatment coverage that includes drugs, dosages, and administration in an easy-to-read tabular format
  • Convenient icons and a consistent chapter design
  • Numerous clinical color photos and didactic diagrams
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Sep 232017
 

Aging Well with Diabetes: 146 Eye-Opening (and Scientifically Proven) Secrets That Prevent and Control Diabetes (Bottom Line)


By (author): Bottom Line Inc.

Diabetes is epidemic in the United States, especially if you’re over the age of 50. Even if you’re already being diligent about your health, a diagnosis can feel like an overwhelming extra burden.

The editors of Bottom Line Inc. present Aging Well with Diabetes, the first book for mature men and women looking to prevent and control diabetes with insight from over 500 of the world’s top health experts! It provides easy access to the trusted collection of information that Bottom Line is known for, and offers breakthroughs on a vast array of topics, including:

• Foods that fight diabetes
• Weight loss and exercise essentials
• Heart health and blood pressure secrets
• Natural treatments and the right tests

Whether you’re hoping to get better control of your diabetes, or facing the first shock of a diagnosis, Bottom Line is here to help you confidentially tackle diabetes.

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Sep 222017
 

Frontiers in Clinical Drug Research – Diabetes and Obesity: Volume 3


By (author): Atta Ur-Rahman

Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The third volume of this series features 5 chapters that cover a variety of topics including: -Exendin-4 and its derivatives -The growth hormone/insulin-like growth factor system -Insulin and cardiovascular function -Diabetes mellitus related infertility -Adipocytokines as markers of insulin resistance
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Sep 142017
 

Diabetes Care for the Older Patient: A Practical Handbook


Features: Diabetes Care for the Older Patient

The management of older people with diabetes requires careful attention to the specific needs of this age group. This practical handbook addresses the issues surrounding the care of older diabetic patients, including dementia, frailty, depression and cardiovascular risk. Intended for day-to-day use in clinical practice, each chapter closes with a list of salient practical points in the clinical management of older patients with diabetes. Concisely written by authorities in the field, this book is a valuable resource for all those involved in the diabetes care of older people .
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Sep 142017
 

Immune Metabolism in Health and Tumor (Advances in Experimental Medicine and Biology)


This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients.

The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of these pathways can lead to immune disorders. In different contexts, such as a tumor microenvironment, immune-cell function and identity may be modified not only by cytokines and checkpoint molecules, but also by nutrient availability and other metabolic stimuli. Transcriptional reprogramming confers many of the changes in immune cell metabolism that are seen when a T-cell, for example, undergoes activation or functional adaptation to different environments. Lastly, immune cells can destructively or protectively participate in human metabolic homeostasis or disorders.

This book summarizes immune-metabolism from a variety of different perspectives, including the ways in which metabolic cues, pathways, and requirements of immune cells change in conditions of homeostasis and activation. The exploration of the significance of metabolic checkpoints and other cues, particularly in the context of cancer and immune disorders, may form the foundation for the development of therapeutics.

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Sep 082017
 

Prevention of Type 2 Diabetes: From Science to Therapy


Features: Prevention of Type 2 Diabetes

There is a world-wide epidemic on obesity. This epidemic is driving the immense proportions of Type 2 diabetes across the globe. While there are numerous therapies for treating Type 2 diabetes, the most effective therapy is prevention. Prevention of Type 2 diabetes can be achieved properly by simultaneous prevention of obesity. Prediabetes, or metabolic syndrome, is the period between simple obesity and diabetes, and this critical period needs to be identified in a more consistent and systematic manner by clinicians worldwide. Clinical trials have indicated that diabetes prevention can be achieved by lifestyle changes and also by certain medications, though none are yet approved for use in prevention. On the other hand, there are funding agencies such as the NIH, CDC, and State Institutions that are interested in studying the prevention paradigms in different communities and ethnic minorities who are most prone to this epidemic. For these reasons, this title by renowned physician-scientist Derek LeRoith is both timely and vitally important for academic physicians, practitioners, allied health care providers, analysts, community activists, and all others interested in this increasing epidemic. This book provides a unique and comprehensive synthesis of the prevention and early diagnosis of Type 2 Diabetes, focusing on identifying risk factors and then moving into topics that address how to prevent their progression to full-blown diabetes. The difficult task of changing patients’ behavior is given special emphasis. The chapters in this practical volume are written by a wide range of international experts, reflecting the editor’s distinguished, internationally renowned career. The volume is organized in eight sections: an introduction to the overall issue of prevention, definitions of values based on ADA guidelines, pathophysiology, discussion of a range of interventional trials regarding prevention, and an overview of state-of-the-art clinical management approaches. Comprehensive and timely, Prevention of Type 2 Diabetes: From Science to Therapy is an essential reference for those treating and researching Type 2 Diabetes.
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Sep 042017
 

Metabolomics: From Fundamentals to Clinical Applications (Advances in Experimental Medicine and Biology)


This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented.

For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions. 
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Sep 022017
 

Endocrinology of the Testis and Male Reproduction


This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

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Sep 022017
 

Principles of Endocrinology and Hormone Action


This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

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Aug 312017
 

Thyroid Nodules: Diagnosis and Management (Contemporary Endocrinology)


Utilizing the most current evidence, this practical book is the first publication of its kind to focus exclusively on the clinical and laboratory evaluation and therapy of thyroid nodules, including advances in evaluation and controversies in management. Opening with chapters presenting the epidemiology, history, laboratory and clinical evaluation of thyroid nodules, the use of radioactive isotope ultrasound and CT scanning in diagnosis is then described. The interpretation of thyroid cytology following fine needle aspiration (FNA) biopsies and the use of molecular markers are discussed in detail, as is the controversial use of thyroxine therapy. Following a presentation of the common and minimally invasive surgical approaches to thyroid nodules, chapters on multinodal goiters, incidentalomas and thyroid nodules in children round out the presentation.

Written and edited by leading US and international thyroidologists, Thyroid Nodules is a useful, state-of-the-art text for endocrinologists, surgeons, and primary care physicians. 

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