This revised and updated second edition contains multiple microscopic illustrations of all diagnostic entities and ancillary techniques, providing a comprehensive, authoritative guide to all aspects of serous effusions. It now includes the many new antibodies which have been tested since the previous edition, as well as a discussion on next-generation sequencing and molecularly targeted therapy.
Section one covers diagnosis for benign and malignant effusions while section two discusses biology, therapy, and prognosis highlighting clinical approaches that may be of value.
Serous Effusions provides an indispensable guide to all aspects of current practice for cytopathologists, cytotechnicians, pathologists, clinicians and researchers in training and practice.
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Cancer Pharmacology and Pharmacotherapy Reviewis the first book devoted entirely to providing the “must-know” facts on each cancer agent, including their pharmacokinetics, FDA-approved indications,toxicity, interactions, and other important information that is commonly found on board examinations and essential for any clinician or practitioner to review. The authors, an oncologist and two pharmacists, have developed a handy question-and-answer format to present the material in digestible bursts.
As the pharmacology section continues to represent a major portion of the medical oncology exam and a key component on oncology MOC exams, this portable study guide will help prepare anyone looking to fine-tune their knowledge on cancer drugs before the test. Not to mention, with recent advancements in the field of cancer treatment, it has become more cumbersome to recall and maintain essential knowledge of every cancer therapeutic, making this book not only an exam resource but also a handy quick reference for oncologists and pharmacists alike.
Conveniently organized and arranged by drug class and subtypes for easier recall and classification
Includes proper dosage adjustments to account for liver and kidney dysfunction
Features tables throughout that provide quick reference regarding FDA-approved medications
Simplified diagrams and illustrations facilitate the pharmacokinetic processes
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This book reviews the standard diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS) and examines ongoing research developments in the field. The importance of appropriate prognostic stratification, taking into account recent advances in understanding of the molecular pathogenesis of MDS, is explained, and both established and novel treatment approaches are discussed in depth. The coverage includes, for example, the use of erythropoietic stimulating agents, iron chelation therapy, the immunomodulator lenalidomide, hypomethylating agents such as azacitidine, and allogeneic hematopoietic stem cell transplantation.
Myelodysplastic syndromes are heterogeneous and complex hematologic disorders ranging from indolent conditions to forms approaching the aggressiveness of acute myeloid leukemia. The diversity of MDS gives rise to challenges in diagnosis and clinical decision making, and the highly variable clinical course necessitates a risk-adapted treatment strategy and the application of disease-specific therapies. Hematologists, oncologists, and other interested clinicians will find this book to be an invaluable source of information on diagnostic and prognostic evaluation and treatment selection.
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Practical Surgical Pathology of the Breast is a comprehensive and accessible guide for the practicing pathologist and trainee. It provides anatomic pathologists with the essential knowledge and tools to navigate breast cases and classification systems that are commonly and uncommonly found in everyday practice. Particularly challenging topics such as understanding the molecular mechanisms linked to breast cancer and the interpretation of molecular tests, are covered in clear prose, along with useful discussions on diagnostic challenges written by world experts. The use of immunohistochemistry in breast pathology is discussed in detail and how to apply it to resolve diagnostic problems. As a result, the book simplifies difficult-to-master issues such as recognizing therapy-induced changes to breast specimens and identifying borderline breast lesions and many more.
Each chapter features high-quality images and stains, tables that emphasize differential diagnoses, text that highlight common diagnostic pitfalls with corresponding tips, as well as helpful key points and how to reach an accurate diagnosis using appropriate procedures and tests. With Practical Surgical Pathology of the Breast as a guide, practitioners and residents can hone their diagnostic skills, resolve difficult cases and improve their approach to breast cases in their daily practice.
-Written by world-renowned breast pathology experts
-Emphasizes the differential diagnosis problem-solving process found in everyday practice
-Contains over 700 high-quality images including numerous immunohistochemical stains which are essential when comparing breast entities
-Includes detailed coverage of core biopsy interpretation, precursors of mammary carcinoma and their mimics, papillary lesions, flat epithelial atypia, adenosis, microinvasive carcinoma, carcinomas with good prognosis, mesenchymal lesions, triple negative carcinomas, lymphomas of the breast, and interpretation of therapy-related changes
-Highlights diagnostic pitfalls and common problems that a pathologist will encounter and includes practical tips throughout to guide the proper interpretation of breast lesions and the proper application of tests to reach accurate diagnoses
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Through step-by-step anatomical photographs, it clearly depicts the Ivor-Lewis operative and Ivor-Lewis-Mckeown operative techniques. Using a consistent format, it addresses the clinical anatomy, pre-operative considerations, operative steps, post-operative care, and pearls and pitfalls to make it easy-to-read.
The authors emphasize the similarities of the principles and steps between open and laparoscopic surgery, which significantly simplifies the transition from one practice to the other. This Atlas also includes a description of anesthesia techniques, a guide to the use of staplers in laparoscopic surgery, and a comparison of the energy sources available for laparoscopic surgery, while also outlining future developments, e.g. the increasing prevalence of robotic surgery for these procedures.
The Atlas offers an essential guide for practitioners and trainees, laparoscopic and thoracoscopic surgeons, and experienced esophageal surgeons who are preparing to change to minimal invasive techniques for the management of esophageal carcinoma. It will also benefit all surgeons who are seeking clear photos detailing how to perform these esophageal carcinoma operations.
From embryology to epidemiology, pathophysiology, diagnosis, complications, treatment and prognosis, this book provides a comprehensive overview and the latest evidence-based data on pancreaticobiliary maljunction (PBM), a congenital malformation in which the pancreatic and bile ducts join anatomically outside the duodenal wall. Resulting in various pathologic conditions, such as biliary cancer and pancreatitis, immediate prophylactic surgery is recommended upon diagnosis.
The standard operative procedure for congenital biliary dilatation (CBD) is extrahepatic bile duct resection with bilioenteric anastomosis, but the optimal treatment of adult patients with PBM without biliary dilatation remains highly debatable. This book, written by pioneering editors and authors provides latest data, sheds new light on the disease.
With abundant figures to aid understanding, Pancreaticobiliary Maljunction and Congenital Biliary Dilatation appeals to a wide readership, especially adult and pediatric surgeons, physicians including gastroenterologists and endoscopists, as well as radiologists and pathologists.
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The current healthcare system is under attack by market, government, and consumer forces. To stay solvent, organizations must be performing at the top of their game. This book provides detailed instructions to bring organizations to the next level of performance by teaching all the secrets straight from the healthcare consultant’s playbook in less than 100 days.
This book defines the coming challenges in the healthcare environment and provides a 10-step solution to develop the infrastructure for peak performance. These solutions include detailed implementation plans, software, reports, metrics, and the top projects that yield the highest financial rewards.
This is the first book of its kind to not just discuss the top strategies, but also provide step-by-step instructions to achieve results. The book defines the strategy, the tactics, the infrastructure, the targets, the solutions, the barriers, and the leadership required to achieve a high performing organization. With these simple instructions, any organization with the will to achieve a brighter future can be poised for success in the next decade in less than 100 days.
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Written from the viewpoint of the practicing clinician, this text is an indispensable addition to the library of anyone who is in the practice of medicine, osteopathy, or chiropractic, as well as for the judge, lawyer, or social worker who may interact with those presenting with the possibility of malingering.
Other topics discussed include Waddell’s Signs, the Pinocchio Phenomenon, the Othello Error, the Menace Reflex, the Reliable Digit Span, Lombard’s Test, the Babinski Sign of the Eyebrow, the Hummel Double Conversation Test, the Swinging Story Test, the Judd-Persaud Test, the Teal Test, the Chimani-Moos Test, the Occlusion Effect, the Drop Arm Test, the Drop Leg Test, the Honest Palm Sign, the Elbow-Flex-Ex Sign, Beevor’s Sign, Schober’s Test, the Babinski Trunk-Thigh Test, and the Barré Test.
Advance praise for Neurological Malingering
“Dr. Hirsch’s book is long overdue and covers a critical topic of concern to all medical practitioners. This comprehensive treatise is a must for all physicians, psychologists, and others who work with patients who have incentive to gain from the system. Multiple topics related to malingering are presented in 16 straightforward chapters never before compiled in a single volume. I recommend this book highly to anyone concerned about malingering and its impact on the medical system.” – Richard L. Doty, PhD, FAAN, Professor and Director, Smell and Taste Center, Perelman School of Medicine, University of Pennsylvania
“Malingering affects not only the malingerers, but the persons and institutions around them as well. As a lay person, the readings have certainly made me considerably more sensitive to suspect behavior. And where knowledge of the underlying condition can affect relationships or transactions one is associated with, it is certainly useful to not only recognize its existence, but also to put it within the context of the challenges that it presents to those relationships or transactions. I count the time spent reading this most comprehensive work as well spent. I would further recommend it to others whose interests, decisions and/or professional pursuits could very well be affected by malingering, whether the behavior is or is not purposeful.” – Judge Stephen A. Schiller (Retired), Circuit Court of Cook County, Illinois
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