Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

 Oncology  Comments Off on Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach
Dec 072019
 

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
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Genetics : a guide for students and practitioners of nursing and health care

 Genetics, Nursing  Comments Off on Genetics : a guide for students and practitioners of nursing and health care
Dec 072019
 

From the
Foreword by Candy Cooley: “What a delight it is … to read a book which takes complex scientific concepts and ensures they are understandable by all.”
With activities and answers, reflection points and a glossary, this interactive textbook supports the ‘Fit for Practice in the Genetics Era’ competence framework, offering an introduction to the theory of genetics and then using common genetic conditions/disorders as case studies to help students apply theory to practice and examine the service user experience. Genetics is written by an experienced teacher of health care sciences and is ideal for students of nursing, healthcare and for a wide range of health care practitioners.

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https://nitroflare.com/view/D617BFDF4BB098B/Genetics__a_guide_for_students_and_practitioners_of_nursing.epub

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Clinical Epidemiology: Practice and Methods (Methods in Molecular Biology)

 Epidemiology  Comments Off on Clinical Epidemiology: Practice and Methods (Methods in Molecular Biology)
Dec 072019
 

Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology assessment, clinical practice guidelines, development of health policy, translational research, how to utilize administrative databases, and knowledge translation. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and practical advice to ensure real world success.
Comprehensive and authoritative, Clinical Epidemiology: Practice and Methods, Second Edition is intended to educate researchers on how to undertake clinical research and should be helpful not only to medical practitioners but also to basic scientists who want to extend their work to humans, to allied health professionals interested in scientific evaluation, and to trainees in clinical epidemiology.

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Minimally Invasive Spine Surgery: Surgical Techniques and Disease Management

 Surgery  Comments Off on Minimally Invasive Spine Surgery: Surgical Techniques and Disease Management
Dec 072019
 

Over the past decade, minimally invasive techniques have developed rapidly and are widely applied in the management of spine disorders. With the development of enabling technologies, including specifically designed spinal retractor systems, intraoperative imaging and navigation technologies, and real-time neural monitoring, minimally invasive spine surgery (MISS) techniques are safe, effective and reproducible. Indeed, studies have confirmed the clinical and economic advantages of these procedures.
Minimally Invasive Spine Surgery includes detailed discussions of enabling technologies, surgical techniques (including posterior decompression and fusion), approaches to specific diseases and conditions, as well as strategies to manage the unique risks and complications of MISS. Generously illustrated, this will be an essential reference for orthopedic surgeons, neurosurgeons and all health care professionals who treat the spine.

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https://nitroflare.com/view/2FCF96C00059FA7/Minimally_Invasive_Spine_Surgery_Surgical_Techniques_and_Di.pdf

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Hypertrophic Cardiomyopathy: Foreword by Bernard Gersh and Historical Context by Eugene Braunwald

 Cardiovascular  Comments Off on Hypertrophic Cardiomyopathy: Foreword by Bernard Gersh and Historical Context by Eugene Braunwald
Dec 072019
 

This book provides a comprehensive clinical review of Hypertrophic Cardiomyopathy (HCM), the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level, resulting in the development of abnormal and occasionally focal hypertrophy on a macroscopic level.
Editor, Srihari S. Naidu, has brought together a world renowned group of experts to review various different topics but, with a practical focus that will enable readers to establish the evidence-based best practice in any potential scenario. Treatment modalities including medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) will be discussed. Chapters on genetics, family screening, lifestyle concerns, and athletic screening have additionally been added given the ongoing controversies and differences of opinion on many of these issues.
Each chapter within Hypertrophic Cardiomyopathy begins with key points of knowledge and ends with clinical pearls that have not previously been disseminated to the wider community. The practical approach of the entire book continues with dedicated chapters on creating a Center of Excellence, including how to facilitate the multi-disciplinary approach, and on case-based reviews and discussions allowing readers to further understand how to integrate the knowledge gained from each chapter into the comprehensive and longitudinal care of the individual patient and family. The last chapter takes the reader through the management of actual patients, showing over decades the nuances to diagnosis and management and the sometimes abrupt changes in the course of their diseases that necessitate correspondingly abrupt modifications in treatment.
This book will be an essential text for Trainees, Fellows, Residents and board-certified physicians in cardiology, interventional cardiology, cardiac surgery, cardiac imaging, sports medicine, paediatric cardiology, genetics and genetic counselling, and electrophysiology.

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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

 Oncology  Comments Off on Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics
Dec 072019
 

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.

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https://nitroflare.com/view/EED2FE8AD9BE0B2/3030240991.epub

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Skin Aging & Cancer: Ambient UV-R Exposure

 Dermatology, Oncology  Comments Off on Skin Aging & Cancer: Ambient UV-R Exposure
Dec 072019
 

This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation. Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body. This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer. The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells. It also elucidates the potential of nanotechnology in the treatment of skin cancer. Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.

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https://nitroflare.com/view/9997E9542EF926D/9811325405.pdf

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Diseases of Poverty: Epidemiology, Infectious Diseases, and Modern Plagues

 Epidemiology, Infectious Diseases  Comments Off on Diseases of Poverty: Epidemiology, Infectious Diseases, and Modern Plagues
Dec 072019
 

Only a few decades ago, we were ready to declare victory over infectious diseases. Today, infectious diseases are responsible for significant morbidity and mortality throughout the world.

This book examines the epidemiology and social impact of past and present infectious disease epidemics in the developing and developed world. In the introduction, the authors define global health as a discipline, justify its critical importance in the modern era, and introduce the Millennium Development Goals, which have become critical targets for most of the developing world. The first half of the volume provides an epidemiological overview, exploring early and contemporary perspectives on disease and disease control. An analysis of nutrition, water, and sanitation anchors the discussion of basic human needs. Specific diseases representing both “loud” and “silent” emergencies are investigated within broader structures of ecological and biological health such as economics, education, state infrastructure, culture, and personal liberty. The authors also examine antibiotic resistance, AIDS, malaria, tuberculosis, and pandemic influenza, and offer an epilogue on diseases of affluence, which now threaten citizens of countries both rich and poor.

A readable guide to specific diseases, richly contextualized in environment and geography, this book will be used by health professionals in all disciplines interested in global health and its history and as a textbook in university courses on global health.

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https://nitroflare.com/view/C611A2C9FC0C942/1611687519.pdf

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The Profession of Dietetics: A Team Approach

 Miscellaneous  Comments Off on The Profession of Dietetics: A Team Approach
Dec 072019
 

The Profession of Dietetics is a succinct, user-friendly introduction to the field of dietetics. It reviews the history of dietetics, gives an overview of the profession as it is today, provides a thorough examination of the educational and credentialing requirements, and projects future trends in the field. The Fourth Edition takes a practical and personal approach to successfully maneuvering the often complicated and competitive steps to success in the nutrition profession.

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https://nitroflare.com/view/5C95F5FBDDF368F/0763790060.pdf

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Cultural Competencies For Nurses: Impact On Health And Illness

 Nursing  Comments Off on Cultural Competencies For Nurses: Impact On Health And Illness
Dec 072019
 

This Text Is A Resource To Help The Nurse At All Levels Navigate Through The Obstacles That Culture Can Place On The Patient Experience. It Compiles The History And Theory Behind Cultural Competency In Nursing And Offers Key Information Regarding Health Beliefs And The Impact Of Culture On Health And Illness.

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https://nitroflare.com/view/4D3F0F4CC84F3FD/0763756504.pdf

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