Paediatric Dentistry fourth edition combines in-depth theoretical information and practical clinical skills to produce a highly relevant resource for undergraduate dentistry students and indeed any clinician in the field. With a user-friendly design, this new edition continues the extensive use of key points, advice on further reading and directions to important evidence. As a result this texts acts as both an essential study tool and a quick reference guide for the surgery. Paediatric Dentistry fourth edition contains a comprehensive survey of every important aspect in the field, including oral pathology, prevention and treatment of dental caries, and restorative dentistry.
The book now offers over 550 illustrations, including clinical photographs and information-packed diagrams. Explanations of key clinical procedures are supported by step-by-step illustrations encorporating photographs, x-ray scans and line drawings. Updated throughout, a new chapter on safeguarding children has also been included in order to prepare the reader for the role they might play in protecting the health and wellbeing of vulnerable children. This reflects the child-centred approach that is integrated throughout the text.
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This book gathers selected, extended and revised contributions to the 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE2018), and the 3rd Conference on Imaging and Visualization, which took place on 26-29 March, 2018, in Lisbon, Portugal. The respective chapters highlight cutting-edge methods, e.g. new algorithms, image analysis techniques, and multibody modeling methods; and new findings obtained by applying them in biological and/or medical contexts. Original numerical studies, Monte Carlo simulations, FEM analyses and reaction-diffusion models are described in detail, together with intriguing new applications.
The book offers a timely source of information for biologists, engineers, applied mathematicians and clinical researchers working on multidisciplinary projects, and is also intended to foster closer collaboration between these groups.
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This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment.
The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells.
This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.
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This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obesity, including an ever -increasing number of other diseases such as type 2 diabetes, cardiovascular diseases and cancer, as well as conditions such as arthropathy, asthma, non-alcoholic liver disease, and dementia. Increasingly recognized uniting causes highlight the role of systemic, local and paracrine actions of adipocytokines in causing inflammation. As we come to better understand how hypothalamic control of energy balance is influenced by endocrine signaling from the gut and adipose tissue, it paves the way for new therapeutic targets and a resurgence of pharmacological and surgical approaches to treatment.
Written by respected experts in the field, this volume is intended as a major reference source for endocrinologists, nutritionists, basic and clinical scientists alike.
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This authoritative reference surveys mind-body healing concepts and psychosomatic medicine in diverse countries and regions of the world. It provides practical insights on the Western division between medical and mental healing and useful information concerning recent efforts to bridge that enduring divide, particularly in the use of ancient and indigenous healing knowledge in psychosomatic practice.
Coverage compares and contrasts current applications of psychosomatic medicine and/or consultation-liaison psychiatry as conducted in such representative countries as France, Britain, China, India, Argentina, Canada, and the United States. And the book predicts how this synthesis of traditions and advances will progress as it:
Traces the history and development of psychosomatic medicine.
Reviews contributions of traditional healing methods to psychosomatic medicine.
Analyzes national styles of psychosomatic medicine as practiced in specific countries.
Compares the status of psychosomatic medicine / consultation-liaison psychiatry in various countries.
Considers the future of psychosomatic medicine as the field, and the world, evolves.
Global Psychosomatic Medicine and Consultation-Liaison Psychiatry expands the knowledge base for psychiatrists, primary care physicians, psychiatric and primary care residents, medical students, behavioral medicine specialists, and others who are interested global and regional perspective on providing biopsychosocial care. It is also relevant for advanced students in health psychology and behavioral medicine, and for professionals in related health fields.
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This revised edition of Charles Brook’s Handbook of Clinical Pediatric Endocrinology provides endocrinologists and pediatricians in training with a fully up-to-date clinical guide presenting evidence-based practice in the diagnosis, treatment, and management of pediatric endocrine disorders. New chapters include “Endocrine complications of chronic disease” and “Endocrine neoplasia.” In addition, the chapter structure has been revamped for easier access and now includes: a key points overview, multiple-choice questions for self-assessment, common errors/pitffalls (in treatment, diagnosis, etc.) boxes, a key weblinks box, a table comparing different society guidelines, diagnostic decision trees, therapeutics decision trees, and a summary.