Nucleic Acid Detection and Structural Investigations

 Nuclear Medicine  Comments Off on Nucleic Acid Detection and Structural Investigations
Nov 022019
 

This book volume provides in depth coverage of the nucleic acid field and aims to represent a broad diversity of the methodologies and a wide range of nucleic-acid-related topics within the fields of molecular biology and biomedicine. Chapters are divided in three sections detailing in vitro detection, nanotechnology and imaging, biomedical applications, and big data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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The Pathophysiologic Basis of Nuclear Medicine

 Nuclear Medicine, Pathology, Physiology  Comments Off on The Pathophysiologic Basis of Nuclear Medicine
Oct 282019
 

This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions. The book starts by providing essential information on general pathophysiology, cell structure and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells. The clinical applications of nuclear medicine are then presented in a series of chapters that cover every major organ system and relate the basic knowledge of anatomy, physiology and pathology to the clinical utilization of various scintigraphic modalities. The therapeutic applications of nuclear medicine are discussed in a separate chapter, and the final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures.
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Radiation Protection in Nuclear Medicine

 Nuclear Medicine  Comments Off on Radiation Protection in Nuclear Medicine
Oct 052019
 


This book explains clearly and in detail all aspects of radiation protection in nuclear medicine, including measurement quantities and units, detectors and dosimeters, and radiation biology. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter is devoted to quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the “rules of thumb” for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.
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Radiation, Ionization, and Detection in Nuclear Medicine

 Nuclear Medicine  Comments Off on Radiation, Ionization, and Detection in Nuclear Medicine
Oct 032019
 

This book will serve as the definitive source of detailed information on radiation, ionization, and detection in nuclear medicine. It opens by considering fundamental aspects of nuclear radiation, including dose and energy, sources, and shielding. Subsequent chapters cover the full range of relevant topics, including the detection and measurement of radiation exposure (with detailed information on mathematical modelling); medical imaging; the different types of radiation detector and their working principles; basic principles of and experimental techniques for deposition of scintillating materials; device fabrication; the optical and electrical behaviors of radiation detectors; and the instrumentation used in nuclear medicine and its application. The book will be an invaluable source of information for academia, industry, practitioners, and researchers.
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Nuclear Medicine in Tropical and Infectious Diseases

 Infectious Diseases, Nuclear Medicine  Comments Off on Nuclear Medicine in Tropical and Infectious Diseases
Feb 152019
 

“More than half of the world’s population is at risk of the tropical diseases malaria, leprosy, schistosomiasis, lymphatic filariasis, onchocerciasis, Chagas’ disease, African trypanosomiasis and leishmaniasis and half a billion are infected with at least one of these diseases”. J. H. F. Remme, World Health Organisation, 1993. “If it is true that science is not limited by frontiers and all research Institutions then belong to mankind, so it is natural for each Institution to be responsible for the problems of those who live in the geographic area under its influence. There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology. It is the duty of each Institution to study the particular aspects concerning its geographic region, as missing links of the chain of universal knowledge may be found there.” H. L. de Oliveira, fonner Rector of the University ofSiio Paulo, 1967. “Nuclear Medicine is cost effective, especially in the developing countries. ( … ).
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Essential Nuclear Medicine Physics, Second Edition

 Nuclear Medicine  Comments Off on Essential Nuclear Medicine Physics, Second Edition
Feb 082019
 

Essential Nuclear Medicine Physics provides an excellent introduction to the basic concepts of the daunting area of nuclear physics. Logically structured and clearly written, this is the book of choice for anyone entering the field of nuclear medicine, including nuclear medicine residents and fellows, cardiac nuclear medicine fellows and nuclear medicine technology students. The text is also a handy quick-reference guide for those already working in the field of nuclear physics.This new edition provides a basic introduction to nuclear physics and the interactions of radiation and matter. The authors also provide comprehensive coverage of instrumentation and imaging, with separate chapters devoted to SPECT, PET, and PET/CT. Discussion of radiation biology, radiation safety and care of victims of radiation accidents completes the text, with an appendix containing the latest NRC rules and regulations.Essential Nuclear Medicine Physics presents difficult concepts clearly and concisely, defines all terminology for the reader, and facilitates learning through extensive illustrations and self-assessment questions. Content: Chapter 1 Basic Nuclear Medicine Physics (pages 1–19): Chapter 2 Interactionof Radiationwith Matter (pages 20–28): Chapter 3 Formationof Radionuclides (pages 29–36): Chapter 4 Nonscintillation Detectors (pages 37–51): Chapter 5 Nonimaging Scintillation Detectors (pages 52–64): Chapter 6 Imaging Instrumentation (pages 65–84): Chapter 7 Single?Photon Emission Computed Tomography (SPECT) (pages 85–113): Chapter 8 Positron Emission Tomography (PET) (pages 114–127): Chapter 9 Combined PET/CT Imaging (pages 128–135): Chapter 10 Quality Control (pages 136–150): Chapter 11 Radiation Biology (pages 151–162): Chapter 12 Radiation Dosimetry (pages 163–166): Chapter 13 Radiation Safety (pages 167–173): Chapter 14 Management of Nuclear Event Casualties (pages 174–187): R. A. Powsner, E. R. Powsner and K. Donohoe
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Nuclear Magnetic Resonance, Vol. 40

 Nuclear Medicine  Comments Off on Nuclear Magnetic Resonance, Vol. 40
Jan 312019
 

Content: Preface; Books and reviews; Theoretical and physical asepcts of nuclear shielding; Applications of nuclear shielding; Theoretical aspects of spin-spin couplings; Applications of spin-spin couplings; Nuclear spin relaxation in liquids and gases; Solid-state NMR spectroscopy; NMR of proteins and nucleic acids; NMR of carbohydrates, lipids and membranes; Synthetic macromolecules; NMR of liquid crystals and micellar solutions; NMR in living systems
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Nuclear Magnetic Resonance, Vol. 35

 Nuclear Medicine  Comments Off on Nuclear Magnetic Resonance, Vol. 35
Jan 312019
 

As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth, both as a technique and in its applications. Today’s applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules, which is cov
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Nationwide Response Issues After an Improvised Nuclear Device Attack: Medical and Public Health Considerations for Neighboring

 Nuclear Medicine  Comments Off on Nationwide Response Issues After an Improvised Nuclear Device Attack: Medical and Public Health Considerations for Neighboring
Jan 242019
 

Our nation faces the distinct possibility of a catastrophic terrorist attack using an improvised nuclear device (IND), according to international and U.S. intelligence. Detonation of an IND in a major U.S. city would result in tens of thousands to hundreds of thousands of victims and would overwhelm public health, emergency response, and health care systems, not to mention creating unprecedented social and economic challenges. While preparing for an IND may seem futile at first glance, thousands of lives can be saved by informed planning and decision making prior to and following an attack. In 2009, the Institute of Medicine published the proceedings of a workshop assessing the health and medical preparedness for responding to an IND detonation. Since that time, multiple federal and other publications have added layers of detail to this conceptual framework, resulting in a significant body of literature and guidance. However, there has been only limited planning effort at the local level as much of the federal guidance has not been translated into action for states, cities and counties. According to an informal survey of community preparedness by the National Association of City and County Health Officials (NACCHO), planning for a radiation incident ranked lowest in priority among other hazards by 2,800 local health departments. The focus of Nationwide Response Issues After an Improvised Nuclear Device Attack: Medical and Public Health Considerations for Neighboring Jurisdictions: Workshop Summary is on key response requirements faced by public health and health care systems in response to an IND detonation, especially those planning needs of outlying state and local jurisdictions from the detonation site. The specific meeting objectives were as follows: – Understand the differences between types of radiation incidents and implications of an IND attack on outlying communities. -Highlight current planning efforts at the federal, state, and local level as well as challenges to the implementation of operational plans. -Examine gaps in planning efforts and possible challenges and solutions. -Identify considerations for public health reception centers: how public health and health care interface with functions and staffing and how radiological assessments and triage be handled. -Discuss the possibilities and benefits of integration of disaster transport systems. -Explore roles of regional health care coalitions in coordination of health care response.
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Clinical Applications of Nuclear Medicine Targeted Therapy

 Nuclear Medicine  Comments Off on Clinical Applications of Nuclear Medicine Targeted Therapy
Dec 282018
 


This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy.
The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options.
Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.

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