Nuclear Medicine Companion: A Case-Based Practical Reference for Daily Use

 Nuclear Medicine  Comments Off on Nuclear Medicine Companion: A Case-Based Practical Reference for Daily Use
Jun 112018
 

This book provides all the information required for the optimal use of nuclear medicine techniques, which are undergoing rapid development yet remain underutilized. Each chapter focuses on one particular clinical system or disease area. The first section of each chapter illustrates normal patterns observed on commonly and uncommonly performed scans as a reference and explains when and how the procedures should be performed. The following section illustrates both the imaging patterns of different diseases and the diagnostic role of individual studies.
Comparisons with other modalities are provided, and the rationale for and effective utilization of each study are discussed. The volume includes near 250 case reviews. In addition, the normal patterns on relevant morphologic modalities are documented in an appendix. The book is directed at Nuclear Medicine physicians and technologists with different levels of training and expertise and also at radiologists who practice nuclear medicine and radiology residents.

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Nuclear Medicine

 Nuclear Medicine  Comments Off on Nuclear Medicine
May 252018
 

The material covers traditional aspects of Nuclear Medicine as well as the newest advances in the field. In this handbook, the role of Nuclear Medicine techniques in diagnosis and treatment is presented in conjunction with the essential elements of radiopharmacology, instrumentation and radiation protection.
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Nuclear Pore Complexes in Genome Organization, Function and Maintenance

 Nuclear Medicine  Comments Off on Nuclear Pore Complexes in Genome Organization, Function and Maintenance
Feb 132018
 

 

The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity.
These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome.

 

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Nuclear Receptors: From Structure to the Clinic

 Nuclear Medicine  Comments Off on Nuclear Receptors: From Structure to the Clinic
Feb 062018
 

 

Nuclear Receptors focuses on the structural analysis of nuclear receptors from the initial work using isolated protein domains to the more recent exciting developments investigating the conformational shape of full-length receptor complexes. The book also reviews the structure of key nuclear receptor co-regulatory proteins. It brings together, for the first time, a comprehensive review of nuclear receptor structure and the importance of receptor conformation underpinning allosteric regulation by different ligands (hormone, drugs, DNA response elements, protein-protein interactions) and receptor activity. The nuclear receptor superfamily, including receptors for steroid hormones and non-steroid ligands, are pivotal to normal physiology, regulating processes as diverse as reproduction, metabolism, the immune system and brain development. The first members of the family were cloned over 25 years ago, which heralded in the idea of a superfamily of intracellular receptor proteins that bound small molecule ligands: classical steroid hormones, vitamins, fatty acids and other products of metabolism. These signals are then transmitted through multiprotein receptor-DNA complexes, leading to the regulation of target genes, often in a cell-selective manner. The cloning of the receptor cDNAs also ushered in an era of unparalleled analysis of the mechanisms of action of these ligand-activated transcription factors. ​

 

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Mitochondrial Disorders Caused by Nuclear Genes

 Nuclear Medicine  Comments Off on Mitochondrial Disorders Caused by Nuclear Genes
Feb 012018
 

 

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes. Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.
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Quality in Nuclear Medicine

 Nuclear Medicine  Comments Off on Quality in Nuclear Medicine
Jan 282018
 

 

This comprehensive textbook provides a state of the art overview of the means by which quality in patient care is ensured within the field of nuclear medicine. Acknowledged experts in the field cover both management aspects, such as laws, standards, guidelines, patient safety, management instruments, and organisations, and specific issues, including radiation safety and equipment. Quality in Nuclear Medicine not only presents detailed information on the topics discussed but should also stimulate further discussion and offer an important tool to all professionals in the field of nuclear medicine and their stakeholders. Readers will find that the book provides a wealth of excellent guidance and reflects the pioneering role of nuclear medicine in advancing different aspects of quality within medicine.
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Nuclear Cardiology Study Guide: A Technologist’s Review for Passing Specialty Certification Exams

 Cardiovascular, Nuclear Medicine  Comments Off on Nuclear Cardiology Study Guide: A Technologist’s Review for Passing Specialty Certification Exams
Dec 072017
 

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The Pulvinar Thalamic Nucleus of Non-Human Primates: Architectonic and Functional Subdivisions

 Nuclear Medicine  Comments Off on The Pulvinar Thalamic Nucleus of Non-Human Primates: Architectonic and Functional Subdivisions
Dec 042017
 

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Breast Cancer: Nuclear Medicine in Diagnosis and Therapeutic Options by Emilio Bombardieri

 Nuclear Medicine, Oncology  Comments Off on Breast Cancer: Nuclear Medicine in Diagnosis and Therapeutic Options by Emilio Bombardieri
Nov 302017
 

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Nuclear Oncology From Pathophysiology to Clinical Applications, Second Edition

 Nuclear Medicine, Oncology, Physiology  Comments Off on Nuclear Oncology From Pathophysiology to Clinical Applications, Second Edition
Nov 032017
 

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