Functional Neuroimaging in Exercise and Sport Sciences

 Neurology/Neurosurgery, Radiology, Sports Medicine  Comments Off on Functional Neuroimaging in Exercise and Sport Sciences
Nov 212019
 

Regular physical exercise is associated with substantial health benefits. Recent evidence not only holds for cardiovascular effects promoting “physical health”, but also for the central nervous system believed to promote “brain health”. Moderate physical exercise has been found to improve learning, memory, and attentional processing, with recent research indicating that neuroprotective mechanisms and associated plasticity in brain structure and function also benefit. Physical exercise is also known to induce a range of acute or sustained psychophysiological effects, among these mood elevation, stress reduction, anxiolysis, and hypoalgesia. Today, modern functional neuroimaging techniques afford direct measurement of the acute and chronic relation of physical exercise on the human brain, as well as the correlation of the derived physiological in vivo signals with behavioral outcomes recorded during and after exercise. A wide range of imaging techniques have been applied to human exercise research, ranging from electroencephalography (EEG), magnetoencephalography (MEG), near infrared spectroscopy (NIRS), magnetic resonance imaging (MRI) to positron emission tomography (PET). All of these imaging methods provide distinct information, and they differ considerably in terms of spatial and temporal resolution, availability, cost, and associated risks. However, from a “multimodal imaging” perspective, neuroimaging provides an unprecedented potential to unravel the neurobiology of human exercise, covering a wide spectrum ranging from structural plasticity in gray and white matter, network dynamics, global and regional perfusion, evoked neuronal responses to the quantification of neurotransmitter release. The aim of this book is to provide the current state of the human neuroimaging literature in the emerging field of the neurobiological exercise sciences and to outline future applications and directions of research.
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Clinical Neurology – 2018

 Neurology/Neurosurgery  Comments Off on Clinical Neurology – 2018
Nov 212019
 

Topics include: evaluation of weakness, neuropathy, myasthenia gravis, demyelinating disease including MS and Guillain-Barre, carpal tunnel, cerebellar disorders, movement disorders (tics, Tourette, dystonia..), tremors, Parkinsons, cerebral palsy, ALS, seizures, strokes, headaches, coma, cervical spine problems, low back pain, radiculopathy, sciatica, myofacial pain, sacroiliac dysfunction, ankylosing spondylitis and pseudo-neurological syndromes.

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Societal Impact of Headache: Burden, Costs and Response

 Neurology/Neurosurgery  Comments Off on Societal Impact of Headache: Burden, Costs and Response
Nov 202019
 

This volume describes the impact of headache disorders on public health, and their adverse consequences for society. It opens with an overview of relevant headache disorders before describing, qualitatively, how the burdens attributable to these disorders fall upon adults, adolescents and children.
In the second section, beginning with a methodological introduction discussing the principles and potential pitfalls of epidemiological studies assessing prevalence, headache-attributed burden and functional impact, the burdens of headache including financial cost are examined quantitatively and in detail. The third section critically reviews society’s response, its inadequacies and the scope for improvement. Topics here include the political failure to recognize the public ill-health and cost that are the consequences of inadequate headache care; the role of the WHO in addressing the problem; headache service organization, delivery and quality; and the effectiveness and cost-effectiveness of interventions. The book closes by considering the way forward. This volume contains important messages for primary care and is likely to be of even greater interest to headache specialists and those concerned with public health and health policy.

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Neuropsychology of Everyday Functioning

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Nov 192019
 

While neuropsychological testing can accurately detect cognitive deficits in persons with brain injury, the ability to reliably predict how these individuals will function in everyday life has remained elusive. This authoritative volume brings together well-known experts to present recent advances in the neuropsychological assessment of key real-world capacities: the ability to live independently, work, manage medications, and drive a car. For each of these domains, contributors describe cutting-edge tests, procedures, and interpretive strategies and examine salient theoretical and methodological issues. Chapters also review approaches for evaluating specific populations, including older adults and patients with traumatic brain injury, depression, dementia, schizophrenia, and other neurological and psychiatric disorders.
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Mechanisms and Emerging Therapies in Tremor Disorders

 Neurology/Neurosurgery  Comments Off on Mechanisms and Emerging Therapies in Tremor Disorders
Nov 182019
 

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented.
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Phytochemicals, Signal Transduction, and Neurological Disorders

 Neurology/Neurosurgery  Comments Off on Phytochemicals, Signal Transduction, and Neurological Disorders
Nov 182019
 

This book offers comprehensive information on bioavailability and mechanism of action of phytochemicals in the brain, and traces the molecular mechanism associated with beneficial effects of phytochemicals in neurotraumatic and neurodegenerative diseases.
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Reverberations: A Daughter’s Meditations on Alzheimer’s

 Neurology/Neurosurgery  Comments Off on Reverberations: A Daughter’s Meditations on Alzheimer’s
Nov 162019
 

Most people think Alzheimer’s Disease is the same as memory loss, if they think about it at all. But most people prefer to ignore it, hoping that if they ignore it hard enough, it will go away. That was certainly Marion Agnew’s hope, even after she knew her mother’s diagnosis. Yet, with her mother’s diagnosis, Marion’s world changed. Her mother — a Queen’s and Harvard/Radcliffe-educated mathematician, a nuclear weapons researcher in Montreal during Word War II, an award-winning professor and researcher for five decades, wife of a history professor, and mother of five — began drifting away from her.

To keep hold of her, to remember her, she began paying attention, and began writing what she saw. She wrote as her mother became suspicious on outings, as she lost even the simplest of words, as she hallucinated, as she became frightened and agitated. But after her mother’s death, Marion wanted to honour the time of her mother’s life in which she had the disease, but she didn’t want the illness to dominate the relationship she’d had with her mother. This moving memoir looks at grief and family, at love and music. It is a coming-to-terms reflection on the endurance of love and family.

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The Neuroscience of Handwriting: Applications for Forensic Document Examination

 Neurology/Neurosurgery  Comments Off on The Neuroscience of Handwriting: Applications for Forensic Document Examination
Nov 162019
 

The Daubert trilogy of U.S. Supreme Court cases has established that scientific expert testimony must be based on science grounded in empirical research. As such, greater scrutiny is being placed on questioned document examination generally, and handwriting comparison in particular. Bridging the gap between theory and practice, The Neuroscience of Handwriting: Applications in Forensic Document Examination examines the essential neuroscientific principles underlying normal and pathological hand motor control and handwriting.

Topics discussed include:

– Fundamental principles in the neuroanatomy and neurochemistry of hand motor control and their application to research in handwriting

– The epidemiology, pathophysiology, and motor characteristics of neurogenerative diseases such as Parkinson’s, Huntington’s, Alzheimer’s, multiple sclerosis, essential tremor, and motor neuron disease and their effects on handwriting

– Psychotropic medications prescribed for depression, bipolar disorder, and psychosis; their mechanisms of action; and their effect on motor behavior and handwriting

– The impact of substance abuse on handwriting

– An overview of the aging process and its effects on motor control and handwriting

– The kinematic approach and new findings on the kinematic analyses of genuine, disguised, and forged signatures

– The authors’ laboratory research on authentic and forged signatures

An essential resource for professionals and researchers in the forensic documentation examination and legal communities, this volume provides a window on the scientific process of signature and handwriting authentication, integrating the extensive research on neural processes and exploring how disease, medication, and advanced age alter these processes.

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Introduction to Neuropsychotherapy

 Neurology/Neurosurgery  Comments Off on Introduction to Neuropsychotherapy
Nov 152019
 

This groundbreaking volume provides a theoretical overview and clinical guidelines for the application of neuropsychotherapy. It takes a multidisciplinary approach, combining neuropsychological knowledge with recent conceptualizations from neuroscience and psychotherapy, with special emphasis on the role of working alliance.

The first part of the book focuses on the historical roots of neuropsychotherapy. Then, a framework of interpersonal process in neuropsychotherapy and conceptualization for clinical purposes are described. Resistance is described through a historical perspective of conceptualizations to the present-day demands of understanding this phenomenon in the process of neuropsychotherapy. In addition, the neuropsychology of emotions is presented in a therapeutic process through a case intervention.

The latter chapters of the book are concerned with special interest interventions and psychotherapeutic working methods suited for neuropsychotherapy.

Representing a wide variety of theoretical, research oriented, clinical neuropsychological and psychotherapeutic expertise, this book will interest professionals in neuropsychological rehabilitation and those working with patients with cognitive, emotional and behavioral disorders in in-patient and out-patient settings.

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Essentials of Geriatric Neuroanesthesia

 Anesthesiology, Geriatrics, Neurology/Neurosurgery  Comments Off on Essentials of Geriatric Neuroanesthesia
Nov 142019
 

The book covers topics ranging from basic sciences (developmental changes in neuroanatomy and neurophysiology and effects of neuropharmacology) to special situations such as brain death, ethical issues and palliative care. It discusses various neurological surgical problems and their challenges along with common problems such as Alzheimer’s and Parkinson’s disease. A section on Pain covers all possible modalities for relieving pain in this patient population followed by the important issue of palliative care. The book addresses the issue of cognition decline, common in this group. The fact that basic sciences are included along with clinical sciences makes it a unique read for the audience.

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