Invertebrate Immunity

 Immunology  Comments Off on Invertebrate Immunity
Oct 102019
 

It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
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Biomarkers for Immunotherapy of Cancer: Methods and Protocols

 Immunology  Comments Off on Biomarkers for Immunotherapy of Cancer: Methods and Protocols
Sep 272019
 

This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy. The editors secured the input from experts in the field dedicated to translating scientific research from bench to bedside was submitted. The book provides not only details about the technical, standardization and interpretation aspects of the methods but also introduces the reader to the background information and scientific justification for selected biomarkers and assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
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Handbook of nutrition and immunity

 Immunology  Comments Off on Handbook of nutrition and immunity
Sep 122019
 

An international panel of physicians, pediatricians, immunologists, and public health nutritionists concisely review for front-line health care providers and researchers the practical aspects related to evaluating nutrition and immunology in the field. Here, the busy physician and investigator will quickly find a clear and up-to-date understanding of the essential immunological facts in adult and child nutrition. Citing the latest research findings, the authors explain the role of nutrition in the case of current health issues, such as HIV, malaria, food allergies, diarrhea, acute respiratory infections, and the impact of macro- and micronutrient deficiencies, dietary fat, and antioxidants on immune status. A compact disk accompanies the book for downloading an ebook version to the reader’s PC or PDA. Comprehensive and holistic, the Handbook of Nutrition and Immunity illuminates for busy health care providers and scientists the interaction and linkages between nutrition and immunology and provides an up-to-date understanding of the practical problems associated with evaluating nutritional and immune status in the field.

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Gut flora, nutrition, immunity, and health

 Immunology  Comments Off on Gut flora, nutrition, immunity, and health
Sep 092019
 

Some foods, as well as contributing essential nutrients to the body, also contain additional components that improve disease resistance and general health status over and above that induced by ingestion of conventional foods. The so-called functional foods, and prebiotics and probiotics exemplify the relationship that exists between nutrition, the gut (the largest element of the body’s immune system) and its flora, immunology and health.This important book contains chapters covering the basic principles of nutrition, gut microecology and immunology, as well as chapters which discuss the way in which this knowledge may be used to explain the positive and negative effects of food consumption, metabolism, probiotics and prebiotics. Food hypersensitivity and allergic reactions, carcinogenesis, and the role of nutrition in the reduced immunity of the aged are also discussed in detail.The editors of this exciting and informative book, who between them have a vast wealth of knowledge of the area, have drawn together and carefully edited international contributions from many well known and respected workers in the area. Gut Flora, Nutrition, Immunity and Health provides essential information for a range of professionals including nutritionists, dietitians, food scientists, microbiologists, gastroenterologists, immunologists and all personnel working in the development and use of functional foods and supplements, prebiotics and probiotics. Libraries in universities and research establishments where these subjects are studied and taught, and pharmaceutical and food companies should have multiple copies of this very useful book on their shelves.Roy Fuller is a consultant in gut microecology, based in Reading, UK; Gabriela Perdigón is based at the Centro de Referencia para Lactobacillus (CERELA) and at the Faculty of Biochemistry, Chemistry and Pharmacy of Tucuman University, Argentina.
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High-yield immunology

 Immunology  Comments Off on High-yield immunology
Aug 312019
 

This book extracts the most important information on immunology and presents it in a concise, uncluttered fashion to prepare students for the USMLE. High-Yield means exactly that
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Nutrition and Immunity

 Immunology, Nutrition  Comments Off on Nutrition and Immunity
Aug 312019
 

This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation.
Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.

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Immunobiology

 Immunology  Comments Off on Immunobiology
Aug 292019
 

Focusing on immunobiology, this text summarizes the basic immunological concepts, covers adaptive immunity and integrates the material at the level of the complete organism in both health and disease. Other topics covered include: allergies; the action of cytokines; and HIV and AIDS.
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Advances in multiple Sclerosis and Experimental Demyelinating Diseases

 Immunology, Microbiology  Comments Off on Advances in multiple Sclerosis and Experimental Demyelinating Diseases
Aug 272019
 

“There is a need for a paradigm shift in our thinking about the pathogenesis of multiple sclerosis.”
Challenging Charcot’s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.
Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination. This book examines the correlation between axonal loss and clinical deficits, including the implied role of the CD8+ T cell and perforin. It assesses proteases, specifically, kallikrein 6, which are strongly associated with active demyelination. By directing natural autoantibodies against oligodendrocytes that demonstrate remyelination in animal models, the authors envision clinical trials for remyelination enhancement.

As internationally recognized specialists in a wide range of MS disciplines, the authors explore genetic tools for identifying patients who are most likely to experience spontaneous remyelination. Epidemiology studies offer additional avenues of treatment. Examples include uric acid, statin drugs, estrogen and progesterone.

MS affects nearly 400,000 people in the United States, many of whom are between18 and 40 years of age. With their novel, multifaceted approach to basic science—and their applications in understanding cause and treatment—the authors offer help to clinicians and hope to patients.

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Recombinant antibodies for immunotherapy

 Immunology  Comments Off on Recombinant antibodies for immunotherapy
Aug 262019
 

Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, “arming” mAbs, novel alternative Ab constructs, increasing half-lives, alternative concepts employing non-immunoglobulin scaffolds, novel therapeutic approaches, a market analysis of therapeutic mAbs, and future developments in the field. The concepts and technologies are illustrated by examples of recombinant antibodies being used in the clinic or in development. This book will appeal to both newcomers and experienced scientists in the field, biology and biotechnology students, research and development departments in the pharmaceutical industry, medical researchers, clinicians, and biotechnology investors.
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Pulmonary Manifestations of Primary Immunodeficiency Diseases

 Immunology  Comments Off on Pulmonary Manifestations of Primary Immunodeficiency Diseases
Aug 242019
 

This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.

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