Discusses advances in antibody engineering and recognition of small molecules. Focuses on new basic and applied science in hapten and assay chemistry and formats. Explores developing methods that improve sensitivity, allow real-time repeated analyses and multi-analyte analysis. Provides data validation guidelines and quality standards for immunoassay methods. Includes an introductory chapter by Bruce D. Hammock and Shirley J. Gee.
Content: Impact of emerging technologies on immunochemical methods for environmental analysis / Bruce D. Hammock and Shirley J. Gee — Recombinant antibodies against haptenic mycotoxins / Heather A. Lee, Gary Wyatt, Stephen D. Garrett, Maria C. Yanguela, and Michael R.A. Morgan — Sequence analysis of individual chains of antibodies to triazine herbicides / Sabine B. Kreissig, Vernon K. Ward, Bruce D. Hammock, and Prabhakara V. Choudary — Recombinant antibodies to diuron : a model for the phenylurea combining site / Christopher W. Bell, Victoria A. Roberts, Karen-Beth G. Scholthof, Guisheng Zhang, and Alexander E. Karu — Antidioxin monoclonal antibodies : molecular modeling of cross-reactive congeners and the antibody combining site / Larry H. Stanker, Adrian Recinos, III, and D. Scott Linthicum — Antibody mimics obtained by noncovalent molecular imprinting / Lars I. Andersson, Ian A. Nicholls, and Klaus Mosbach — Type reactivity for analyte profiling / Lawrence M. Kauvar and Peter Y.K. Cheung — Analytical representation and prediction of macroscopic properties : a general interaction properties function / Peter Politzer, Jane S. Murray, Tore Brinck, and Pat Lane — Strategies for immunoassay hapten design / Marvin H. Goodrow, James R. Sanborn, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock — Hapten versus competitor design strategies for immunoassay development / Robert E. Carlson — Miniaturized microspot multianalyte immunoassay systems / Roger P. Ekins and Frederick W. Chu — Very sensitive antigen detection by immuno-polymerase chain reaction / Takeshi Sano, Cassandra L. Smith, and Charles R. Cantor — Self-regenerating fiber-optic sensors / David R. Walt, Venetka Agayn, and Brian Healey — Fiber-optic immunosensors for detection of pesticides / Mohyee E. Eldefrawi, Amira T. Eldefrawi, Nabil A. Anis, Kim R. Rogers, Rosie B. Wong, and James J. Valdes — Liposome-amplified immunoanalysis for pesticides / Stuart G. Reeves, Sui Ti A. Siebert, and Richard A. Durst — Polarization fluoroimmunoassay for rapid, specific detection of pesticides / Sergei A. Eremin — Immunoaffinity chromatography applications in pesticide metabolism and residue analysis / Rosie B. Wong, Joseph L. Pont, David H. Johnson, Jack Zulalian, Tina Chin, and Alexander E. Karu — Development of assay for analysis of Hg² based on sulfur-containing ligands / Ferenc Szurdoki, Horacio Kido, and Bruce D. Hammock — Interpretation of immunoassay data / James F. Brady — Guidelines to the validation and use of immunochemical methods for generating data in support of pesticide registration / Charles A. Mihaliak and Sharon A. Berberich — Quality standards for immunoassay kits / James Rittenburg and Joseph Dautlick — Immunochemical approach for pesticide waste treatment monitoring of s-triazines / Mark T. Muldoon and Judd O. Nelson — Evaluation and application of immunochemical methods for mycotoxins in food / Mary W. Trucksess and Donald E. Koeltzow — Immunodetection of ecosystem contaminants : research, application, and acceptance in Canada / James P. Sherry.
GET IT FREE HERE