Epigenome Editing: Methods and Protocols

 Laboratory Medicine  Comments Off on Epigenome Editing: Methods and Protocols
Mar 132018
 

This detailed book explores the concepts and applications of epigenome editing, as presented by leading scientists in the field. Beginning with some general and topical reviews, the collection continues by covering the design of DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level.
Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Epigenome Editing: Methods and Protocols will be of great assistance to people new to the field but also to those already engaged, as epigenetic editing is still a relatively unexplored field with many issues to be resolved.

 

 

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A Clinician’s Guide to Sperm DNA and Chromatin Damage

 Laboratory Medicine  Comments Off on A Clinician’s Guide to Sperm DNA and Chromatin Damage
Mar 112018
 

This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors.
Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm.

We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician’s Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.

 

 

http://nitroflare.com/view/F8E088002C5B6A8/3319718142.epub

 

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Medical Parasitology: A Textbook

 Laboratory Medicine  Comments Off on Medical Parasitology: A Textbook
Feb 112018
 

 

This textbook will provide a systematic comprehension of the various medically important human parasites; their distribution, habitat, morphology and life cycle, pathogenesis and clinical features, laboratory diagnosis, treatment, prevention and control. The main emphasis is on the protozoan and helminthic diseases, also medical entomology covering vectors relevant to these diseases.
The book aims to promote an easy yet comprehensive way of learning parasitology. It attempts to break down the complexity of medical parasitology into parts that are easy to understand yet integrating the essential information of parasitic infections. The integration of knowledge of parasites will be achieved through student friendly illustrations, inclusion of a collection of recent case reports, examples of test questions and scenarios, and the images of human parasites. Essentially, it provides a “one-stop learning package” for medical parasitology.

 

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http://nitroflare.com/view/B15E0AE242C6D15/3319687948.epub

 

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A Manual of Laboratory and Diagnostic Tests (9th edition)

 Laboratory Medicine  Comments Off on A Manual of Laboratory and Diagnostic Tests (9th edition)
Jan 042018
 

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Laboratory Manual for Comparative Veterinary Anatomy & Physiology, 2 edition

 Laboratory Medicine  Comments Off on Laboratory Manual for Comparative Veterinary Anatomy & Physiology, 2 edition
Nov 032017
 

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Functional Genomics, Third Edition

 Laboratory Medicine  Comments Off on Functional Genomics, Third Edition
Oct 162017
 

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Microfluidics for Medical Applications

 Laboratory Medicine  Comments Off on Microfluidics for Medical Applications
Aug 142017
 

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Laboratory Diagnosis in Neurology

 Laboratory Medicine, Neurology/Neurosurgery  Comments Off on Laboratory Diagnosis in Neurology
Aug 142017
 

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http://nitroflare.com/view/5CB5ACA44824684/3131441011.mobi

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Clinical Core Laboratory Testing

 Laboratory Medicine  Comments Off on Clinical Core Laboratory Testing
Jul 282017
 

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Molecular Diagnostics Part 2: Clinical, Veterinary, Agrobotanical and Food Safety Applications

 Laboratory Medicine  Comments Off on Molecular Diagnostics Part 2: Clinical, Veterinary, Agrobotanical and Food Safety Applications
Jul 202017
 

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