Activity-Based Protein Profiling

 Immunology, Microbiology  Comments Off on Activity-Based Protein Profiling
Feb 182019
 

This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.
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Epigenetics: Development and Disease

 Microbiology  Comments Off on Epigenetics: Development and Disease
Feb 112019
 

Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological conditions. This volume presents contributions from worldwide experts presenting their research and findings, including: the evolution of epigenetic machineries from archaea to higher eukaryotes; role of epigenetics in development and transcription regulation; epigenetic landscape of human disease; a chemical biology approach to understanding epigenetic phenomena; exploration of different small molecules as epigenetic therapies. This volume is aimed at students and researchers of chromatin biology and epigenetics and will also be of interest to a broader pharmaceutical audience.
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The Microbiological Safety of Food in Healthcare Settings

 Microbiology  Comments Off on The Microbiological Safety of Food in Healthcare Settings
Feb 082019
 

Drawing together the work of a wide range of experts, this extremely important book provides a clear, practical account of the salient features of foodborne pathogenic microorganisms and of the particular risks that they pose to vulnerable groups of the population in hospitals, nursing and residential homes, nurseries, and in the community at large. Chapters cover the following topics: • Properties and importance of microorganisms that cause foodborne disease• Surveillance of foodborne disease• Occurrence of foodborne disease in healthcare settings• Vulnerable groups of the population• Provisions for food and water • Implementation of safety systemsPresenting a wealth of information of great importance, this comprehensive and well-edited book is a vital resource for physicians, doctors and nurses responsible for the control of infection, clinicians, physicians, public health doctors and specialists, those responsible for catering management, microbiologists, environmental health officers, food scientists and food technologists. It is also designed to be accessible to policy makers and administrators who may not have specialist training. Libraries in all universities, research establishments and medical schools where these subjects are studied and taught should have copies of this essential work on their shelves.Content: Chapter 1 Overview (pages 1–11): Patrick G. WallChapter 2 Properties of Microorganisms that Cause Foodborne Disease (pages 12–233): Barbara M. LundChapter 3 The Surveillance of Foodborne Disease and its Application in Healthcare Settings (pages 234–250): John M. Cowden and Jacqui ReillyChapter 4 Foodborne Disease Outbreaks in Healthcare Settings (pages 251–289): Sarah J. O’BrienChapter 5 Vulnerable Populations and their Susceptibility to Foodborne Disease (pages 290–319): David W.K. Acheson and Lisa F. LubinChapter 6 Provision of Food in Healthcare Settings (pages 320–336): Dinah BarrieChapter 7 Provision of Water in Healthcare Settings (pages 337–350): Paul R. HunterChapter 8 Practical Implementation of Food Safety Management Systems in Healthcare Settings (pages 351–380): Jon?Mikel Woody and Dianne L. Benjamin
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Microbial Physiology, Fourth Edition

 Microbiology, Physiology  Comments Off on Microbial Physiology, Fourth Edition
Feb 082019
 

The Fourth Edition of Microbial Physiology retains the logical, easy-to-follow organization of the previous editions. An introduction to cell structure and synthesis of cell components is provided, followed by detailed discussions of genetics, metabolism, growth, and regulation for anyone wishing to understand the mechanisms underlying cell survival and growth. This comprehensive reference approaches the subject from a modern molecular genetic perspective, incorporating new insights gained from various genome projects.Content: Chapter 1 Introduction to Microbial Physiology (pages 1–26): Chapter 2 Macromolecular Synthesis and Processing: DNA, RNA, and Protein Synthesis (pages 27–100): Chapter 3 Bacterial Genetics: DNA Exchange, Recombination, Mutagenesis, and Repair (pages 101–170): Chapter 4 Microbial Physiology in the Genomic Era: A Revolutionary Tale (pages 171–193): Chapter 5 Regulation of Prokaryotic Gene Expression (pages 194–238): Chapter 6 Bacteriophage Genetics (pages 239–276): Chapter 7 Cell Structure and Function (pages 277–349): Chapter 8 Central Pathways of Carbohydrate Metabolism (pages 350–367): Chapter 9 Energy Production and Metabolite Transport (pages 368–393): Chapter 10 Metabolism of Substrates Other Than Glucose (pages 394–411): Chapter 11 Fermentation Pathways (pages 412–433): Chapter 12 Photosynthesis and Inorganic Metabolism (pages 434–449): Chapter 13 Lipids and Sterols (pages 450–474): Chapter 14 Nitrogen Metabolism (pages 475–502): Chapter 15 Biosynthesis and Metabolism of Amino Acids (pages 503–544): Chapter 16 Purines and Pyrimidines (pages 545–560): Chapter 17 Bacterial Cell Division (pages 561–581): Chapter 18 Microbial Stress Responses (pages 582–611): Chapter 19 Bacterial Differentiation (pages 612–647): Chapter 20 Host–Parasite Interactions (pages 648–675):
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Microbiology with Diseases by Body System, 5th Edition

 Microbiology  Comments Off on Microbiology with Diseases by Body System, 5th Edition
Feb 012019
 

Dr. Robert Bauman’s Microbiology with Diseases by Body System, 5th Edition helps students visualize the invisible and practice critical thinking with real-world problems and clinical applications. The textbook includes QR codes for Dr. Bauman Video Tutors and Disease in Depth features that foster understanding and encourage students to explore microbiology. The continued focus on clinical situations prepares students for future opportunities in applied practice and healthcare careers. With the 5th Edition, new Solve the Problem features ask students to work through real-world microbiology problems and offer instructors active-learning worksheets for their course. This edition results from a collaborative effort of educators, students, editors, and top scientific illustrators to deliver a textbook that presents the latest scientific and educational research and data in microbiology.

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Molecular Mechanisms of Microbial Evolution

 Microbiology  Comments Off on Molecular Mechanisms of Microbial Evolution
Jan 042019
 

One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms.
Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis.Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health. Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.

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Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets

 Endocrinology/Metabolism/Diabetes Mellitus, Microbiology  Comments Off on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets
Dec 292018
 

The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

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Therapeutic Microbiology: Probiotics and Related Strategies

 Microbiology  Comments Off on Therapeutic Microbiology: Probiotics and Related Strategies
Nov 192018
 

Breaks new ground in explaining the breakthroughs possible with therapeutic microbiology.

Explores the potential and actual uses of the many methods for altering the microbiotas of humans and animals: probiotics, prebiotics, synbiotics, bacteriophages, and replacement therapy.
Describes the biological principles underlying the manipulation of the indigenous microbiota and the biology of the effector organisms that have been utilized for this purpose.
Discusses the many microbes that can potentially be used therapeutically and prophylactically.
Serves as a reference to medical, dental and veterinary practitioners with an interest in alternative approaches to the prevention and treatment of microbial diseases.

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Advances in Microbiology, Infectious Diseases and Public Health: Volume 9

 Infectious Diseases, Microbiology  Comments Off on Advances in Microbiology, Infectious Diseases and Public Health: Volume 9
Nov 082018
 

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention.
Advances in Microbiology, Infectious Diseases and Public Health is a subseries of Advances in Experimental Medicine and Biology, which has been publishing significant contributions in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. 2016 Impact Factor: 1.881.

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Microbiology: A Laboratory Manual, Global Edition (11th edition – March 30, 2017 Release)

 Microbiology  Comments Off on Microbiology: A Laboratory Manual, Global Edition (11th edition – March 30, 2017 Release)
Oct 202018
 

Easy to adapt for almost any microbiology lab course, this versatile, comprehensive, and clearly written manual is competitively priced and can be paired with any undergraduate microbiology text. Known for its thorough coverage, straightforward procedures, and minimal equipment requirements, the Eleventh Edition incorporates current safety protocols from governing bodies such as the EPA, ASM, and AOAC. The new edition also includes alternate organisms for experiments for easy customization in Biosafety Level 1 and 2 labs. New lab exercises have been added on Food Safety and revised experiments, and include options for alternate media, making the experiments affordable and accessible to all lab programs. Ample introductory material, engaging clinical applications, and laboratory safety instructions are provided for each experiment along with easy-to-follow procedures and flexible lab reports with review and critical thinking questions.

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