May 262017
 

Therapeutic Ribonucleic Acids in Brain Tumors


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In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of these innovative methods in the broad field of central nervous system and brain tumours particularly. Whereas there is currently no comprehensive overview on potential and challenges of nucleic acids technologies for basic brain tumours and for the clinical management of patients with brain tumours, this book does explicitly cover the many other aspects of the “RNA World” (pathogenic and therapeutic potential of microRNAs, aptamer technology, etc.), too. With this significantly broadened scope as compared to currently existing books it appears to be an urgently needed new publication.

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May 262017
 

Mammalian Brain Development (Contemporary Neuroscience)


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Denis Noble Nearly a decade after completion of the first draft of the entire Human Genome sequence we are in a better position to assess the nature and the consequences of that heroic achievement, which can be seen as the culmination of the molecular biological revolution of the second half of the twentieth century. The achievement itself was celebrated at the highest levels (President and Prime Minister) on both sides of the Atlantic, and rightly so. DNA sequencing has become sufficiently c- mon now, even to the extent of being used in law courts, that it is easy to forget how technically difficult it was and how cleverly the sequencing teams solved those problems in the exciting race to finish by the turn of the century [1, 2]. The fanfares were misplaced, however, in an important respect. The metaphors used to describe the project and its biological significance gave the impression to the public at large, and to many scientists themselves, that this sequence would reveal the secrets of life. DNA had already been likened to a computer program [3]. The “genetic program” for life was therefore to be found in those sequences: A kind of map that had simply to be unfolded during development. The even more colo- ful “book of life” metaphor gave the promise that reading that book would lead to a veritable outpouring of new cures for diseases, hundreds of new drug targets, and a brave new world of medicine.
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May 262017
 

The Moral Brain: Essays on the Evolutionary and Neuroscientific Aspects of Morality


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Scientists no longer accept the existence of a distinct moral organ as phrenologists once did. A generation of young neurologists is using advanced technological medical equipment to unravel specific brain processes enabling moral cognition. In addition, evolutionary psychologists have formulated hypotheses about the origins and nature of our moral architecture. Little by little, the concept of a ‘moral brain’ is reinstated.

As the crossover between disciplines focusing on moral cognition was rather limited up to now, this book aims at filling the gap. Which evolutionary biological hypotheses provide a useful framework for starting new neurological research? How can brain imaging be used to corroborate hypotheses concerning the evolutionary background of our species?

In this reader, a broad range of prominent scientists and philosophers shed their expert view on the current accomplishments and future challenges in the field of moral cognition and assess how cooperation between neurology and evolutionary psychology can boost research into the field of the moral brain.

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May 262017
 

Handbook of Stroke (Lippincott Williams & Wilkins Handbook Series)


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By (author): David O. Wiebers, Valery L. Feigin, Robert D. Brown Jr. MD

Thoroughly updated to reflect the best current practices in stroke medicine, Handbook of Stroke, Second Edition is a user-friendly one-stop guide to the clinical management of patients with cerebrovascular disorders—from clinical and laboratory assessment, differential diagnosis, and initial management, to medical and surgical treatment, prognosis, rehabilitation, and stroke prevention. The book is written by leaders in stroke medicine and delivers concise, practice-oriented overviews and practical recommendations to guide decision-making. This edition includes cutting-edge information on acute stroke treatment, cerebrovascular disease genetics, primary stroke prevention, management of unruptured intracranial aneurysms, and the newest therapies for various stroke-related symptoms and disorders.

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May 252017
 

Evolution of the cerebellar sense of self


By (author): John Montgomery, David Bodznick

The cerebellum is an intriguing component of the brain. In humans it occupies only 10% of the brain volume, yet has approximately 69 billion neurons; that is 80% of the nerve cells in the brain. The cerebellum first arose in jawed vertebrates such as sharks, and sharks in fact have an additional cerebellum-like structure that works as an adaptive filter. The function of shark cerebellum-like structures is to discriminate ‘self’ from ‘other’ in sensory inputs. With the evolution of the true cerebellum the adaptive filter functionality was adopted for motor control and paved the way for athleticism and movement finesse that we see in swimming, running, climbing and flying vertebrates.

This book uses an evolutionary perspective to open up the exciting body of work that is cerebellar research to a wide audience. Understanding the brain is of interest to many people, from many different backgrounds, and for many different reasons. Therefore, understanding cerebellum is a significant step towards the wider challenge of understanding the brain.

This book wil be of interest to neuroscientists, neurologists and psychologists, in addition to computer scientists, and engineers concerned with machine/human interactions and robotics.

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May 242017
 

Challenging Topics in Neuroanesthesia and Neurocritical Care


This book focuses on controversial issues in neuroanesthesia and neurocritical care that in general have been subjected to insufficient professional scrutiny. The book is in three parts, the first of which is devoted to topics relating to traumatic brain and spinal cord injury, such as brain tissue oxygenation, the role of biomarkers, and diagnosis of brain death. Aspects of airway and pain management are then addressed, covering, for example, airway management in an emergency setting, airway evaluation in the edentulous patient, and pain management in neurosurgery and after craniotomy. The final part of the book considers a wide range of other challenging subjects in the field of neuroanesthesia and neurocritical care. Throughout, much information is provided on the latest, state of the art management. The authors are acknowledged experts in the issues they discuss, and the book will be of interest for graduate and undergraduate students, residents, neuroanesthetists, neurointensivists, emergency medicine residents and specialists, fellows in neurocritical care and all those directly involved in the perioperative care of patients with head and neck pathology.
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May 232017
 

AARP The Scientific American Healthy Aging Brain: The Neuroscience of Making the Most of Your Mature Mind


By (author): Judith Horstman

AARP Digital Editions offer you practical tips, proven solutions, and expert guidance.  Scientific American and Scientific American Mind have good news about getting older!

AARP The Scientific American Healthy Aging Brain taps into the most current research to present a realistic and encouraging view of the well-aged brain, a sobering look at what can go wrong––and at what might help you and your brain stay healthy longer. Neurologists and psychologists have discovered the aging brain is much more elastic and supple than previously thought, and that happiness actually increases with age. While our short-term memory may not be what it was, dementia is not inevitable. Far from disintegrating, the elder brain can continue to develop and adapt in many ways and stay sharp as it ages. 

  • Offers new insights on how an aging brain can repair itself, and the five best strategies for keeping your brain healthy
  • Shows how older brains can acquire new skills, perspective, and productivity
  • Dispels negative myths about aging
  • Explores what to expect as our brains grow older 

With hope and truth, this book helps us preserve what we’ve got, minimize what we’ve lost, and optimize the vigor and health of our maturing brains.

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May 222017
 

Getting Started with Neurofeedback (Norton Professional Books)


By (author): John N. Demos

What is neurofeedback? Neurofeedback is founded upon computer technology joined with auxiliary equipment that can measure the metabolic activity of the cerebral cortex.

Neurofeedback training combines the principles of complementary medicine with the power of electronics. It is a comprehensive system that promotes growth change at the cellular level of the brain and empowers the client to use his or her mind as a tool for personal healing.Until now, there has not been a single comprehensive yet easy-to-understand guide for clinicians interested in adding neurotherapy to their practice. Getting Started with Neurofeedback is a step-by-step guide for professional health care providers who wish to begin with neurotherapy, as well as experienced clinicians who are looking for a concise treatment guide.This book answers essential questions such as: How does neurotherapy work?, What is the rationale for treatment? When is neurotherapy the treatment of choice? Why should I add it to my already existing healthcare practice? The author also answers questions important to establishing a successful practice such as: What kind of training should clinicians get? What kind of equipment should clinicians buy? How can clinicians add neurofeedback to their existing practice?The first part of the book introduces the reader to the world of neurofeedback, its history and scientific basis. Case studies help clinicians apply what they are learning to their existing practice. Demos takes the mystery out of the assessment process and charts and examples of topographical brain maps (in full color) serve as teaching aids. Later in the book, advanced techniques are explained and demonstrated by additional case studies. The reader is shown how to use biofeedback for the body to augment neurofeedback training as well as being taught to work with the body and acquire a basic knowledge of complementary medicine.The book concludes by offering clinicians practical suggestions on marketing their expanded practice, purchasing equipment, finding appropriate training and supervision, and keeping up with the ever-growing profession of neurofeedback. Research and theory unite to demonstrate the clinical underpinnings for this exciting new modality.

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May 222017
 

Mystery of the Mind: A Critical Study of Consciousness and the Human Brain (Princeton Legacy Library)


By (author): Wilder Penfield

In the past fifty years scientists have begun to discover how the human brain functions. In this book Wilder Penfield, whose work has been at the forefront of such research, describes the current state of knowledge about the brain and asks to what extent recent findings explain the action of the mind. He offers the general reader a glimpse of exciting discoveries usually accessible to only a few scientists.

He writes: “Throughout my own scientific career I, like other scientists, have struggled to prove that the brain accounts for the mind. But perhaps the time has come when we may profitably consider the evidence as it stands, and ask the question…Can the mind be explained by what is now known about the brain?”

The central question, he points out, is whether man’s being is determined by his body alone or by mind and body as separate elements. Before suggesting an answer, he gives a fascinating account of his experience as a neurosurgeon and scientist observing the brain in conscious patients.

Originally published in 1975.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

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May 212017
 

Case Studies in Dementia: Common and Uncommon Presentations (Case Studies in Neurology)


Dementia is amongst the greatest challenges facing the medical profession as the population ages. Accurate diagnosis is essential as many rarer forms of the disease are treatable if recognized early. This collection of case studies from around the world illustrates both common and unusual causes of dementia, emphasizing clinical reasoning, integrative thinking and problem-solving skills. Each case consists of a clinical history, examination findings and special investigations, followed by diagnosis and discussion. The aim is to reinforce diagnostic skills through careful analysis of individual presenting patterns, and to guide treatment decisions, using state-of-the-art diagnostic classification and tools. The reader will be able to distinguish patients who need reassurance, closer follow-up or immediate referral to specialized services. Written and edited by internationally recognized experts in dementia, these case studies will inform and challenge clinicians at all stages of their careers.
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