Jul 202017
 

The Newborn at High Risk of Brain Damage: EURope Against Infant Brain Injury (EURAIBI) International Workshop, Siena, April 2001 (Biology of the Neonate)


Special Topic Issue: Biology of the Neonate 2001, Vol. 79, No. 3-4 In the last 10 years it has become evident that the etiology of neonatal brain injury is multifactorial and that cerebral palsy is only caused by birth asphyxia in a minority of cases. A number of risk factors for developing brain injury other than asphyxia and oxidative stress, such as inflammation and environmental factors, suggest that prevention may be possible, but first a more thorough understanding of the mechanisms leading to brain injury is required. This issue brings together the work of leading scientists on the risk factors for neonatal brain injury, on high-risk newborns, mechanisms leading to injury and new therapeutic approaches. It should be of interest to obstetricians, paediatricians, neonatologists, neurologists, neuropathologists and all those concerned with the care of newborns.
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Jul 202017
 

Neurogenesis in the Adult Brain I: Neurobiology


The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.

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Jul 182017
 

Cell Therapy Against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials


This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.

Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.

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Jul 182017
 

Continuous EEG Monitoring: Principles and Practice


This book is designed to meet the need for a practically oriented textbook on the rapidly growing field of continuous EEG (cEEG) monitoring. A wide range of key clinical aspects are addressed, with explanation of status epilepticus classification, criteria for institution of monitoring, seizure patterns and their recognition, quantitative EEG analysis, and neuroimaging in patients undergoing cEEG monitoring. The value of cEEG and the nature of cEEG findings in various special situations are then reviewed, covering particular pathologies, critical care considerations, and prognostication. Treatments of nonconvulsive status epilepticus (NCSE) and nonconvulsive seizures (NCS) are discussed. The concluding section is devoted to important administrative issues including billing, staffing issues, comparison of EEG machines, and information technology (IT) issues.
Continuous EEG monitoring offers the only reliable means of detecting seizures that are not clinically obvious in critically ill patients. Such seizures are common: approximately 20% of patients undergoing cEEG monitoring in hospital have NCSE or NCS. Against this background, many hospitals have started to offer cEEG monitoring as a basis for delivery of appropriate treatment. By presenting the state of the art in cEEG monitoring, this book will be invaluable to practitioners including neurophysiologists, neurologists, neurointensivists, intensivists, neurophysiology and epilepsy fellows, and neurology residents. 
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Jul 172017
 

Looking Inside the Brain: The Power of Neuroimaging


By (author): Denis Le Bihan

It is now possible to witness human brain activity while we are talking, reading, or thinking, thanks to revolutionary neuroimaging techniques like magnetic resonance imaging (MRI). These groundbreaking advances have opened infinite fields of investigation?into such areas as musical perception, brain development in utero, and faulty brain connections leading to psychiatric disorders?and have raised unprecedented ethical issues. In Looking Inside the Brain, one of the leading pioneers of the field, Denis Le Bihan, offers an engaging account of the sophisticated interdisciplinary research in physics, neuroscience, and medicine that have led to the remarkable neuroimaging methods that give us a detailed look into the human brain.

Introducing neurological anatomy and physiology, Le Bihan walks readers through the historical evolution of imaging technology?from the x-ray and CT scan to the PET scan and MRI?and he explains how neuroimaging uncovers afflictions like stroke or cancer and the workings of higher-order brain activities, such as language skills. Le Bihan also takes readers on a behind-the-scenes journey through NeuroSpin, his state-of-the-art neuroimaging laboratory, and goes over the cutting-edge scanning devices currently being developed. Considering what we see when we look at brain images, Le Bihan weighs what might be revealed about our thoughts and unconscious, and discusses how far this technology might go in the future.

Beautifully illustrated in color, Looking Inside the Brain presents the trailblazing story of the scanning techniques that provide keys to previously unimagined knowledge of our brains and our selves.

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Jul 172017
 

From Basic Pain Mechanisms to Headache (Frontiers in Headache Research Series)


Though the topics of pain and headache are obviously linked, these two research fields have in recent years developed at their own pace, often with scant attention paid to the other. This book brings together researchers and clincians from the forefront of these two disciplines to explore how the basic pain mechanisms relate to migraine and other forms of headache.
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Jul 162017
 

Diffuse Low-Grade Gliomas in Adults


The second edition of this well-received volume has been revised and updated to reflect the  advances in pathological classification and molecular epidemiology of diffuse low-grade gliomas (DLGG) in adults and offers an updated review on individualized therapies. This book presents the latest research pertaining to the diagnosis, genetics, therapy and management of DLGGs.  It extensively covers recent research on the natural history of DLGGs and their interaction with the brain and reviews the new diagnostic and therapeutic strategies which increase survival and quality of life of the patient.

New topics covered are the management of DLGGs during pregnancy, functional rehabilitation of patients with DLGG and the onco-functional balance in DLGG, among others. The reader will have the opportunity to gain insight in both clinical and basic science aspects of this type of tumor and learn about the application of novel imaging techniques such as diffussion tensor imaging.   

Edited by a leading expert in the field and authored by a team of recognised specialists, this book is a valuable resource for medical oncologists, neuro-oncologists and neurologists.
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Jul 162017
 

When the Air Hits Your Brain: Tales of Neurosurgery


By (author): Jr. Frank T. Vertosick

Told through intimate portraits of a neurosurgeon’s patients, this book contains detailed descriptions of the surgical procedure in neurosurgery. It provides a poignant and often humorous account of the mysteries of the mind and the operating room.
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Jul 152017
 

Brain Hypoxia and Ischemia (Contemporary Clinical Neuroscience)


Features: Used Book in Good Condition

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development.

This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

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Jul 142017
 

Aphasia and Related Neurogenic Communication Disorders


By (author): Ilias Papathanasiou, Patrick Coppens, Constantin Potagas

Aphasia and Related Neurogenic Communication Disorders covers topics in aphasia, motor speech disorders, and dementia. Organized by symptom rather than syndrome, this text provides a foundation for understanding the disorders and learning how to apply basic theory to clinical practice in the development of rehabilitation objectives. Aphasia and Related Neurogenic Communication Disorders applies a clinical integration of the psychosocial with the neuropsychological approach in adult language rehabilitation. Written by international authorities in the field of aphasia and related communication disorders and based on the ICF framework, this unique text features diverse contribution covering global issues.
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