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Pediatric Obesity: Etiology, Pathogenesis and Treatment, 2nd edition

Epidemiology Comments Off

Jan 282018

This second edition of Freemark’s text embodies all of the strengths of the original work but is deeper and broader in scope, with new chapters on emerging themes including metabolomics, genomics, and the roles of gastrointestinal hormones, the microbiome, brown adipose tissue, and endocrine disruptors in the pathogenesis of childhood obesity. Reviews of the effects of weight excess on cognitive performance and immune function complement detailed analyses of the biochemical and molecular pathways controlling the development of childhood adiposity and metabolic disease. Critical assessments of nutritional interventions (including new chapters on infant feeding practices and vegetarian diets) and superb reviews of behavioral counseling, pharmacotherapy, and bariatric surgery provide practical guidance for the management of overweight children. Penetrating analyses of the obesity epidemic in its social, cultural, economic, and political contexts highlight challenges and opportunities for obesity prevention and community action. The perspective is international in scope and reflects the expertise and experience of many of the leading figures in the field.
Comprehensive and up-to-date, this new edition of Pediatric Obesity: Etiology, Pathogenesis and Treatment will be an invaluable guide for all healthcare providers and policy makers concerned with the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic.

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http://nitroflare.com/view/AFC4C8BC55DBCA6/3319681915.pdf

http://nitroflare.com/view/B3E55DC89A42530/3319681915.epub

Advanced Nutrition and Dietetics in Nutrition Support

Nutrition Comments Off

Jan 282018

Written in conjunction with the British Dietetic Association, Advanced Nutrition and Dietetics in Nutrition Support provides a thorough and critical review of the fundamental and applied literature in nutrition support.

Extensively evidence–based and internationally relevant, it discusses undernutrition, nutritional screening, assessment and interventions, as well as key clinical conditions likely to require nutrition support, and the approaches to managing this in each of these conditions.

Clinically oriented, Advanced Nutrition and Dietetics in Nutrition Support is the ideal reference for all those managing undernutrition in a range of clinical areas.

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http://nitroflare.com/view/F99A3699152E684/1118993853.pdf

The APRN’s Complete Guide to Prescribing Drug Therapy 2017

Pharmacology Comments Off

Jan 282018

This is a concise, easy-to-read prescribing reference for advanced health care providers involved in the primary care management of patients with acute, episodic, and chronic health problems. Organized alphabetically by clinical diagnosis for quick access in all clinical settings, the guide encompasses CDC and FDA approved pharmacotherapy regimens for more than 500 clinical diagnoses along with clinically useful information in convenient quick-access format.

Another outstanding feature is the inclusion of pointers throughout the guide highlighting such clinically important information as laboratory values to be monitored, precautions and contraindications, patient teaching points, pediatric usage and dosages, and safety information.

Each diagnosis includes appropriate drug choices listed alphabetically by generic name and Trade name, FDA pregnancy category, drug availability in generic or over-the-counter forms, adult and pediatric dosing regimens, brand names, dosage forms, drug additives, and more. Thirty easy-to-use tables in the appendices include FDA pregnancy categories, U.S. Schedule of Controlled Substances, Childhood and Adult Immunization Schedules, Contraceptive Guidance, categories of Glucocorticosteroids, Anti-infectives by class, and more. An alphabetical cross-reference index of drugs by generic and brand name, with FDA pregnancy category and controlled drug schedule, facilitates quick identification of drugs by alternate names, and relative safety during pregnancy.

Key Features:
• Facilitates speedy drug information retrieval for primary care providers in all settings
• Organizes over 300 diagnoses alphabetically by alternate names for ease of use
• Highlights clinically important information such as lab values to monitor, patient education points, and safety information
• Includes Appendix of 30 tables for quick access to key drug classifications, FDA pregnancy categories, Schedule of • Controlled Substances, Childhood and Adult Immunization Schedules, etc.
• Provides generic/Trade name cross reference reference.

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http://nitroflare.com/view/A170122D27EE5F7/The_APRNs_Complete_Guide_to_Prescribing_Drug_Therapy_2017_-_Mari_J._Wirfs%2C_PhD%2C_MN%2C_APRN%2C_A.epub

Antiepileptic Drugs and Pregnancy: A Guide for Prescribers

Pharmacology Comments Off

Jan 282018

A description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences between the various anti-seizure medications. It also deals with the possible harmful effects of antiepileptic drug exposure during pregnancy on the physical and intellectual development of the fetus. Clinicians have to balance the potential adverse effects of the medicine for the fetus and mother-to-be against the risks that uncontrolled seizures hold for both when treating pregnant women with antiepileptic drugs. Only recently have enough scientific data emerged to provide a rational basis for treatment decisions that take in both aspects. This work provides a single, accessible and up-to-date resource for busy clinicians.

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http://nitroflare.com/view/413FA2D6E2801D9/3319214330.pdf

http://nitroflare.com/view/389178A5DA66B9B/3319214330.epub

Brain and Mind: Subjective Experience and Scientific Objectivity

Neurology/Neurosurgery Comments Off

Jan 282018

Recent advances in the understanding of brain functions are reviewed in this text, along with how neurobiological research and brain imaging contributes to identifying and treating neurologic and psychiatric disorders. Chapters focus on consciousness, memory, emotions, language, communication, trauma, pain and resilience, while exploring how stressful events impact mental health and interrupt the continuity of one’s sense of self. Clinical vignettes of patients with neurological and mental affections reveal coping and grieving processes in dreams and narratives. This presentation of clinical experience with neuro-scientific evidence provides neurologists, psychiatrists, psychotherapists and psychologists with a coherent picture of the brain-mind relationship.

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http://nitroflare.com/view/0C466DA86663F65/3319212869.epub

Budget-Impact Analysis of Health Care Interventions: A Practical Guide

Pharmacology Comments Off

Jan 282018

The first of its kind for budget-impact analysis, this comprehensive guide provides clear and concise instructions for evaluating the impact that new pharmaceuticals will have on the budget for a specific jurisdiction. The book demonstrates how to create a budget-impact analysis using a simple six-step process that is consistent with current guidelines for these analyses. Examples and exercises for each chapter afford an opportunity to practice the six-step process in practical applications.

The book progresses from a framework for budget impact analyses to an in-depth review of components and how to develop and present these in software applications and reports. Critical considerations such as uncertainty analysis and validation, and considerations for alternate interventions, such as vaccines and diagnostics, are also covered.

This book is a “must have” for the builder and budget holder, with builders benefiting from instructions to identify and estimate all necessary variables and budget holders receiving a guide to what should be included in the analyses they assess.

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http://nitroflare.com/view/3F16AF0D6943E08/3319504800.pdf

Cardiovascular Genetics and Genomics: Principles and Clinical Practice

Cardiovascular, Genetics Comments Off

Jan 282018

This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions.
Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

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http://nitroflare.com/view/F06A3D323A81B15/3319661124.epub

http://nitroflare.com/view/220F6BF63BD24D8/3319661124.pdf

Inflammation, Aging and Cancer: Biological Injustices to Molecular Village of Immunity that Guard Health

Oncology Comments Off

Jan 282018

This book was prepared as extension of author’s accidental discoveries on experimental models of acute and chronic ocular inflammatory diseases that were established at the University of Pennsylvania in 1980’s. Analyses of original data suggest a series of first evidence for direct link between inflammation and developmental phases of immune dysfunction in multistep tumorigenesis and angiogenesis.
The only evidence presented on initial events for interactions and synergies between activated host and recruiting cells toward tumorigenesis.
Effective immunity was defined as balance between two highly regulated and biologically opposing arms, Yin and Yang of acute inflammation, an amazingly precise signal communications between immune and non-immune systems requiring differential bioenergetics. Unresolved inflammation is a common denominator mapping aging process and induction of ‘mild’, ‘moderate’ or ‘severe’ immune disorders including cancers.
Our knowledge of the fascinating biology of immunity in health or chronic diseases is fragmentary, chaotic and confusing, particularly for cancer science. Lack of progress in curing majority of chronic diseases or cancer is primarily due to the fact that scientists work on isolated molecules/cells or topics that are funded and promoted by decision makers in medical/cancer establishment. Despite existence of over 25 million articles on cancer-related topics, cancer biology and cure remain mysteries to be solved. After a century of cancer research, the failure rates of therapies for solid tumors are 90% (+/-5). Current reductionist views on cancer science are irresponsible, shut-gun approaches and create chaos. Outcomes are loss of millions of precious lives and economic drain to society. Very little is known about initial events that disturb effective immunity whose function is to monitor and arrest growth of cancerous cells or defend against other external or internal hazardous agents that threaten body’s survival.

The author demonstrates the serious need for systematic understanding of how immune disruptors and aging process would alter effective immunity. Outcomes of proposed orderly studies are expected to provide logical foundations for cost-effective strategies to promote immunity toward a healthier society. The policy makers and medical/cancer establishment are urged to return to the common sense that our Forefathers used to serve the public.

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http://nitroflare.com/view/45CEF2D8CFCB6EB/3319664735.pdf

http://nitroflare.com/view/62E58EFA80D3C02/3319664735.epub

Retinal Prosthesis: A Clinical Guide to Successful Implementation

Ophthalmology Comments Off

Jan 282018

Intended as a useful and practical guide primarily oriented toward ophthalmic practitioners involved in retinal prosthesis implantation and post-operative visual rehabilitation, this book focuses on the Argus II Retinal Prosthesis and its revolutionary incorporation into the practice. The reader will get an update on patient selection, expected visual outcomes, surgical implantation techniques, and post-operative visual rehabilitation. Retinal Prosthesis - A Clinical Guide to Successful Implementation is written in a clear and concise manner and includes diagrams and high quality photographs to demonstrate best practices in surgical techniques and desired outcomes. Covering topics such as history of retinal prostheses, bioengineering considerations, clinical therapies, and other therapies and future directions, this book is written for practicing ophthalmologists, residents, and medical students interested in retinal implants.

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http://nitroflare.com/view/CC93DDBA06675EA/3319672584.pdf

http://nitroflare.com/view/4B8252FE964E658/3319672584.epub

Integration of Omics Approaches and Systems Biology for Clinical Applications

Nephrology Comments Off

Jan 282018

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications

This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed.

Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting.

Describes a range of state of the art omics analytical platforms
Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis
Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer)
Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.

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http://nitroflare.com/view/91F3185BEE45366/1119183952_9781119183952.pdf

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