Infectious Diseases, Microbiology and Virology: A Q&A Approach for Specialist Medical Trainees

 Infectious Diseases, Microbiology  Comments Off on Infectious Diseases, Microbiology and Virology: A Q&A Approach for Specialist Medical Trainees
Feb 272020
 

An essential resource for practitioners in infectious diseases and microbiology, studying for the new FRCPath Part 1 infection examination accredited by the Royal College of Pathologists, and trainees sitting the membership exams of the Royal College of Physicians. Including over 300 multiple choice questions in an exam-style Q&A format, this guide provides an invaluable revision platform for domestic and international trainees alike, with scope to present infection-based support for other medical specialties, where infection forms a core component, including intensive care. Authored by leading specialists in infectious diseases and microbiology, this invaluable training guide is the first of its kind to cover both undergraduate and postgraduate material in infectious diseases. Mapping directly from the FRCPath and RCP infection curricula, students are able to explore areas of curriculum to gain knowledge and optimise decision-making skills, under pressure.

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Microbial Ecology in States of Health and Disease: Workshop Summary

 Microbiology  Comments Off on Microbial Ecology in States of Health and Disease: Workshop Summary
Feb 172020
 

Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction – across the spectrum of hosts, microbes, and environmental niches – that influence the formation, function, and stability of host-associated microbial communities.

Microbial Ecology in States of Health and Disease is the summary of a workshop convened by the Institute of Medicine’s Forum on Microbial Threats in March 2013 to explore the scientific and therapeutic implications of microbial ecology in states of health and disease. Participants explored host-microbe interactions in humans, animals, and plants; emerging insights into how microbes may influence the development and maintenance of states of health and disease; the effects of environmental change(s) on the formation, function, and stability of microbial communities; and research challenges and opportunities for this emerging field of inquiry.
Table of Contents
– Front Matter
– Workshop Overview
– A1 Effector and memory T cell responses to commensal bacteria–Yasmine Belkaid, Nicolas Bouladoux, and Timothy W. Hand
– A2 What are the consequences of the disappearing human microbiota?–Martin J. Blaser and Stanley Falkow
– A3 Pathways in microbe-induced obesity–Laura M. Cox and Martin J. Blaser
– A4 Microbial exposure during early life has persistent effects on natural killer T Cell function–Torsten Olszak, Dingding An, Sebastian Zeissig, Miguel Penilla Vera, Julia Richter, Andre Franke, Jonathan N. Glickman, Reiner Siebert, Rebecca M. Barron, Dennis L. Kasper, and Richard S. Blumberg
– A5 The application of ecological theory toward an understanding of the human microbiome–Elizabeth K. Costello, Keaton Stagaman, Les Dethlefsen, Brendan J. M. Bohannan, and David A. Relman
– A6 Seasonal restructuring of the ground squirrel gutmicrobiota over the annual hibernation cycle–Hannah V. Carey, William A. Walters, and Rob Knight
– A7 Lessons from studying insect symbioses–Angela E. Douglas
– A8 A new vision of immunity: homeostasis of the superorganism–Grard Eberl
– A9 Host defense and immunomodulation of mucosal candidiasis–Paul L. Fidel, Jr., and Mairi C. Noverr
– A10 Microbiota-targeted therapies: An ecological perspective–Katherine P. Lemon, Gary C. Armitage, David A. Relman, and Michael Fischbach
– A11 Community ecology and the vaginal microbiome–Larry J. Forney and Jacques Ravel
– A12 Investigating bacterial-animal symbioses with light sheet microscopy–Michael J. Taormina, Matthew Jemielita, W. Zac Stephens, Adam R. Burns, Joshua V. Troll, Raghuveer Parthasarathy, and Karen Guillemin
– A13 Clinical application of fecal microbiota transplantation in Clostridium difficile infection and beyond–Josbert J. Keller and Els van Nood
– A14 Consumption of human milk glycoconjugates by infant-associated bifidobacteria: Mechanisms and implications–Daniel Garrido, David C. Dallas, and David A. Mills
– A15 Bacteriophage adhering to mucus providea nonhost-derived immunity–Jeremy J. Barr, Rita Auro, Mike Furlan, Katrine L. Whiteson, Marcella L. Erb, Joe Pogliano, Aleksandr Stotland, Roland Wolkowicz, Andrew S. Cutting, Kelly S. Doran, Peter Salamon, Merry Youle, and Forest Rohwer
– A16 Topographic diversity of fungal and bacterial communities in human skin–Keisha Findley, Julia Oh, Joy Yang, Sean Conlan, Clayton Deming, Jennifer A. Meyer, Deborah Schoenfeld, Effie Nomicos, Morgan Park, NIH Intramural Sequencing Center Comparative Sequencing Program, Heidi H. Kong, and Julia A. Segre
– A17 Distinct microbial communities within the endosphere and rhizosphere of Populus deltoides roots across contrasting soil types–Neil R. Gottel, Hector F. Castro, Marilyn Kerley, Zamin Yang, Dale A. Pelletier, Mircea Podar, Tatiana Karpinets, Ed Uberbacher, Gerald A. Tuskan, Rytas Vilgalys, Mitchel J. Doktycz, and Christopher W. Schadt
– A18 Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis–Iliyan D. Iliev, Vincent A. Funari, Kent D. Taylor, Quoclinh Nguyen, Christopher N. Reyes, Samuel P. Strom, Jordan Brown, Courtney A. Becker, Phillip R. Fleshner, Marla Dubinsky, Jerome I. Rotter, Hanlin L. Wang, Dermot P. B. McGovern, Gordon D. Brown, and David M. Underhill
– A19 Metagenomics and personalized medicine–Herbert W. Virgin and John A. Todd
– A20 From genetics of inflammatory bowel disease towards mechanistic insights–Daniel B. Graham and Ramnik J. Xavier
– A21 Antimicrobial peptides and the microbiome–Michael Zasloff
– Appendix B: Agenda
– Appendix C: Acronyms
– Appendix D: Glossary
– Appendix E: Speaker Biographies

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A Guide to Specimen Management in Clinical Microbiology

 Microbiology  Comments Off on A Guide to Specimen Management in Clinical Microbiology
Feb 082020
 

A Guide to Specimen Management in Clinical Microbiology is the classic reference that addresses and meets the needs of everyone in the “total testing process” circle. It provides complete, concise information on the unique needs of the microbiology laboratory regarding specimen management and is the only single source for the specimen management policies required for laboratory results that are accurate, significant, and clinically relevant.
Medical, nursing, and medical technology students, practicing physicians, private practice offices, clinical laboratories, and public health laboratories can turn to this valuable resource to answer their questions on issues such as the correct procedures of specimen selection, collection, transport, and storage in the clinical microbiology laboratory, the rationale associated with the specimen requirements, and proper communication between the lab and its clients.

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Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology)

 Immunology, Microbiology  Comments Off on Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology)
Nov 102019
 

The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. However, clinical and experimental evidence suggests that the importance of an individual factor changes during the course of the disease. Factors and cell types that induce acute autoreactivity and initiate an autoimmune disease could be distinct from those that drive a chronic course of that disease.
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IgE Antibodies: Generation and Function

 Immunology, Microbiology  Comments Off on IgE Antibodies: Generation and Function
Nov 082019
 

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
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Dictionary of Microbiology & Molecular Biology

 Microbiology  Comments Off on Dictionary of Microbiology & Molecular Biology
Nov 052019
 

This Third, Revised Edition of a unique, encyclopaedic reference work covers the whole field of pure and applied microbiology and microbial molecular biology in one volume. The Dictionary of Microbiology and Molecular Biology, Third Edition, Revised: Reflects the latest developments in the fieldFeatures over 18,000 entries from concise definitions of terms to review-length articlesProvides extensive cross-referencing between topicsIncludes numerous references from scientific journals and other relevant sourcesWith its wide-ranging description of different areas of microbiology, the Dictionary of Microbiology and Molecular Biology, Third Edition, Revised is an indispensable reference for every researcher, lecturer and student.
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Lippincott Illustrated Reviews Flash Cards: Microbiology

 Microbiology  Comments Off on Lippincott Illustrated Reviews Flash Cards: Microbiology
Nov 022019
 

Succeed in your course and on the board exam with Lippincott’s Illustrated Reviews Flash Cards: Microbiology! Part of a new series of Lippincott Illustrated Reviews Flash Cards, this handy print and digital card set features artwork from Lippincott’s Illustrated Review of Microbiology, with corresponding key topic and clinical questions for effective course and board review. The set of 200 cards includes three types of questions with icons: . Spot flash (image-based identification questions) . Course review (high-yield info for course or board exam) . Clinical correlations (questions that relate to clinical practice) The Q & A format, high quality images, and different question types facilitate effective drill and maximum recall-making this one of the most convenient and effective study tools available for board review. . Fine tune your understanding with high quality artwork and clear and to-the-point information. . Easily select the card or set of cards you want to focus on using the Index with topic list correlated to flash card numbers (for print cards) and quick online search (for digital cards). . Maximize your study time with the flash card set’s focus on high-yield points, clinical correlations, and bolded key terms from the parent text. . Keep your cards concise, organized, and uncluttered with all card information linking back to the text for additional reference.
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Processes in Microbial Ecology

 Microbiology  Comments Off on Processes in Microbial Ecology
Aug 302019
 

Processes in Microbial Ecology discusses the major processes carried out by viruses, bacteria, fungi, protozoa, and other protists in freshwater, marine, and terrestrial ecosystems.

Written by one of the leading scientists in the field, the text focuses on biogeochemical processes, starting with primary production and the initial fixation of carbon into cellular biomass, before exploring how that carbon is degraded in both oxygen-rich (oxic) and oxygen-deficient (anoxic) environments.

The book neatly connects processes occurring at the micron scale to events happening at the global scale, including the carbon cycle and its connection to climate change issues.

A final chapter is devoted to symbiosis and other relationships between microbes and larger organisms.

Processes in Microbial Ecology is an ideal text for advanced undergraduate and graduate students in microbial ecology and related fields.

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Advances in multiple Sclerosis and Experimental Demyelinating Diseases

 Immunology, Microbiology  Comments Off on Advances in multiple Sclerosis and Experimental Demyelinating Diseases
Aug 272019
 

“There is a need for a paradigm shift in our thinking about the pathogenesis of multiple sclerosis.”
Challenging Charcot’s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.
Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination. This book examines the correlation between axonal loss and clinical deficits, including the implied role of the CD8+ T cell and perforin. It assesses proteases, specifically, kallikrein 6, which are strongly associated with active demyelination. By directing natural autoantibodies against oligodendrocytes that demonstrate remyelination in animal models, the authors envision clinical trials for remyelination enhancement.

As internationally recognized specialists in a wide range of MS disciplines, the authors explore genetic tools for identifying patients who are most likely to experience spontaneous remyelination. Epidemiology studies offer additional avenues of treatment. Examples include uric acid, statin drugs, estrogen and progesterone.

MS affects nearly 400,000 people in the United States, many of whom are between18 and 40 years of age. With their novel, multifaceted approach to basic science—and their applications in understanding cause and treatment—the authors offer help to clinicians and hope to patients.

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Micro-computed Tomography

 Microbiology  Comments Off on Micro-computed Tomography
Aug 272019
 


This book focuses on applications of micro CT, CBCT and CT in medicine and engineering, comprehensively explaining the basic principles of these techniques in detail, and describing their increasing use in the imaging field.
It particularly highlights the scanning procedure, which represents the most crucial step in micro CT, and discusses in detail the reconstruction process and the artifacts related to the scanning processes, as well as the imaging software used in analysis.
Written by international experts, the book illustrates the application of micro CT in different areas, such as dentistry, medicine, tissue engineering, aerospace engineering, geology, material engineering, civil engineering and additive manufacturing.
Covering different areas of application, the book is of interest not only to specialists in the respective fields, but also to broader audience of professionals working in the fields of imaging and analysis, as well as to students of the different disciplines.

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