Neurology of Music

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Apr 102020
 

The first British book on neurology in music was published over 30 years ago. Edited by Drs Macdonald Critchley and R A Henson, it was entitled Music and the Brain (published by Wm Heinemann Medical Books), but all of its contributors are now either retired or deceased. Since then, there has been an increasing amount of research, and the present volume includes the most significant of these advances.
The book begins with the evolutionary basis of meaning in music and continues with the historical perspectives, after which the human nervous system is compared to a clavichord, highlighting the use of metaphor in the history of modern neurology. It discusses the neurologist in the concert hall as well as the musician at the bedside by showing how neurology enriches musical perception, the main theme being the cerebral localisation of music production and perception. The book also emphasises the value of teaching singing to treat speech disorders and the importance of nerve compression in musicians, the final chapter being on recent techniques of imaging the musical brain.

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Good Research Practice in Non-Clinical Pharmacology and Biomedicine

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Mar 262020
 

This book provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

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Sleep, Circadian Rhythms, and Metabolism: The Rhythm of Life

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Mar 172020
 

Providing a nuanced study of the connections between sleep, circadian rhythms, and metabolis, this informative book examines how circadian actions affect the liver and adipose tissue, the brain, and metabolism.

This important book introduces the reader to circadian rhythms in the body and the external cues that set them, discusses on a molecular and organ level how disrupting these clocks results in metabolic and sleep disorders, and looks at the clinical applications of circadian rhythms, with a focus on sleep.

The book covers a variety of important research in the field, including:

• The power of computational biology to uncover new nodes in the network of circadian rhythms

• Circadian rhythms as they relates to obesity

• How late-night shift conditions impair the body’s ability to keep time and promote metabolic diseases and how this can be mitigated by strategic planning of feeding times

• The relationship between the suprachiasmatic nuclei and orexin neurons, demonstrating the elegant interplay between our biological clocks and wakefulness

• How sleep disorders can result from irregular circadian rhythms and potential ways to diagnose this in individuals

• How sleeping behaviors can disturb the hypothalamic-pituitary-adrenal axis and the repercussions of this disruption on female reproduction

• How disruption of sleep can be clinically beneficial for depressed patients

• How mental state is influenced by circadian rhythm

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Empires of Panic: Epidemics and Colonial Anxieties

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Jan 042020
 

Empires of Panic is the first book to explore how panics have been historically produced, defined, and managed across different colonial, imperial, and post-imperial settings―from early nineteenth-century East Asia to twenty-first-century America. Contributors consider panic in relation to colonial anxieties, rumors, indigenous resistance, and crises, particularly in relation to epidemic disease. How did Western government agencies, policymakers, planners, and other authorities understand, deal with, and neutralize panics? What role did evolving technologies of communication play in the amplification of local panics into global events? Engaging with these questions, the book challenges conventional histories to show how intensifying processes of intelligence gathering did not consolidate empire, but rather served to produce critical uncertainties―the uneven terrain of imperial panic.
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Odze and Goldblum Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas – 3rd Revised Edition

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Jan 042020
 

2015 BMA Medical Book Awards 1st Prize Award Winner in Pathology Category! The updated edition of Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas is designed to act as a one-stop medical reference book for the entire gastrointestinal system, providing exhaustive coverage and equipping you with all of the necessary tools to make a comprehensive diagnostic workup. You’ll access thousands of high-quality illustrations and eight brand-new chapters, so you can recognize and diagnose any pathological slide you encounter.

“The 3rd?edition of this multiauthor GI pathology textbook has been expanded & is a must-have for pathologists practising lumenal pathology of the GI tract.”

The updated edition of Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas is designed to act as a one-stop medical reference book for the entire gastrointestinal system, providing exhaustive coverage and equipping you with all of the necessary tools to make a comprehensive diagnostic workup. You’ll access thousands of high-quality illustrations and eight brand-new chapters, so you can recognize and diagnose any pathological slide you encounter.

  • Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
  • Make a comprehensive diagnostic workup with data from ancillary techniques and molecular findings whenever appropriate.
  • Effectively grasp complex topics and streamline decision-making by using extensive tables, graphs, and flowcharts.
  • Avoid diagnostic errors thanks to practical advice on pitfalls in differential diagnosis.
  • Navigate the book quickly with a “road map” featured at the beginning of each chapter.
  • Provide the clinician with the most accurate and up-to-date diagnostic and prognostic indicators, including key molecular aspects of tumor pathology, with access to the latest classification and staging systems available.
  • Evaluate diagnostically challenging cases using diagnostic algorithms.

  • Stay abreast of the latest advances with eight new chapters: Autoimmune Disorders of the GI Tract; Drug Induced Disorders of the GI Tract; Molecular Diagnostics of Tubal Gut Neoplasms; Molecular Diagnostics of the Gallbladder, Extrahepatic Biliary Tree, and Pancreatic Tumors; Tumors of the Ampulla; Molecular Diagnostics of Hepatocellular Neoplasms; Approach to the Liver Biopsy, and Approach to Gastrointestinal Tract Biopsies.
  • Remain at the forefront of your field with coverage of new molecular and genetic markers in GI neoplasms; updated knowledge on liver and biliary tree pathology; and expanded information on tumors of the ampulla.
  • Recognize and diagnose any tissue sample under the microscope with help from over 3000 high-quality color illustrations.

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http://nitroflare.com/view/D9122BFF9CA6C5A/1455707473.pdf

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Practical Medical and Surgical Management of Chronic Rhinosinusitis

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Oct 292019
 

This book is a comprehensive compendium on the medical and surgical treatment of chronic rhinosinusitis (CRS), with or without polyposis. Detailed coverage is provided of a wide range of topics, including medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period and specific medical therapeutic classes currently employed in CRS patients. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects and available clinical efficacy data and emphasizes practical management pearls and pitfalls. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined. The book will be a valuable resource for practicing general otolaryngologists, rhinologists and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners and nurses involved in the care of CRS patients.

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The Drug Development Process: Increasing Efficiency and Cost-Effectiveness (Drugs and the Pharmaceutical Sciences)

 Pharmacology, Uncategorized  Comments Off on The Drug Development Process: Increasing Efficiency and Cost-Effectiveness (Drugs and the Pharmaceutical Sciences)
Oct 272019
 

Containing contributions from the many disciplines involved in a drug’s evolution, this timely volume examines the entire pharmaceutical development process, emphasizing approaches to increasing efficiency and reducing costs.

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Organism Models of Autism Spectrum Disorders (Neuromethods)

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Oct 272019
 

As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab.

Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.

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Clinical Cardiac Electrophysiology in Clinical Practice

 Cardiovascular, Uncategorized  Comments Off on Clinical Cardiac Electrophysiology in Clinical Practice
Oct 272019
 

Cardiac Electrophysiology (EP) is a highly specialized, complex and growing field of cardiology. As understanding of the evaluation of treatment of arrhythmias continues to advance, learning and understanding the principles of EP in order to provide the best possible treatments for patients can be a daunting task. The Manual of Clinical Cardiac Electrophysiology is a guide to the clinical diagnosis and treatment of cardiac arrhythmias that meets this need. With a scientific, practical, and multi-disciplinary approach, the book establishes the foundation of the cardiac electrophysiology and provides multimedia illustrations to facilitate and enhance understanding. These illustrations will come directly from real case studies, to provide an authentic look at each principle of EP. Since the world of EP moves so fast, and arrhythmias are diagnosed and treated in real time, it is often difficult to learn EP from static texts, images and diagrams. This book is designed to be accessible enough to serve as an introduction to EP, but advanced enough to serve as a guide for experienced practitioners. EP students of all levels, including medical students, residents, fellows, mid-level providers, nurses, technologist, primary care providers, cardiologists and electrophysiologists will find value in the Manual of Clinical Cardiac Electrophysiology.

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Macromolecular Anticancer Therapeutics

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Oct 182019
 

In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic concentrations, intrinsic or acquired resistance to the treatment with currently available agents via genetic and epigenetic mechanisms, and toxicity. As a result, cancer therapy using conventional therapeutics and different types of treatment regimens using this therapeutics has not led to a convincing survival benefit of the patients. In this context, Macromolecular therapeutics offer several advantages over conventional low molecular therapeutics by various ways such as, enable the use of larger doses of these agents by limiting the toxicity, by enhanced permeability and retention into tumors, by tumor targeting using tumor-specific antibodies, by specific inhibition of oncogenes using anticancer oligonucleotides etc. Cancer treatment using this macromolecular therapeutics has considerably improved the survival benefit for patients. As a result, various macromolecular therapeutics are already commercialized or are under clinical development. Although we are far from a real magic bullet today, looking at the pace of research and current success in this field of macromolecular therapeutics, it appears that we are approaching a magic bullet for the efficient treatment of cancer. Thus, we believe that the subject of this book is very timely, and that the book will fill an unmet need in the market.
This book is unique and assembles various types and aspects of macromolecular anticancer therapeutics for cancer therapy in one shell and conveys the importance of this interdisciplinary field to the broad audience. Thus, in a nutshell, this book details the basics of cancer, and various therapeutic strategies such as those based on macromolecular therapeutics hence can become an important reference for practitioners, oncologists, medical pharmacologists, medicinal chemists, biomedical scientists, experimental pharmacologists, pharmaceutical technologists, and particularly it can essentially become a handbook of macromolecular therapeutics for cancer therapy for graduates, post-graduates and Ph.D. students in these fields.

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