Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology

 Genetics, Pathology  Comments Off on Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology
Jul 292020
 

In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations.Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.

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Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development

 Pathology  Comments Off on Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development
Jul 232020
 

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepatitis, arthritis, celiac disease, myeloproliferative disorders, neurology, and wound healing. The authors write from years of experience in diagnostic practice and pharmaceutical drug development, aiming to educate pharmaceutical and academic scientists how to best use tissue to diagnose disease and improve the process of drug development.  As part of the Methods in Pharmacology and Toxicology series, this volume is designed to provide wisdom and examples that others can follow and apply as part of drug development.
Comprehensive and practical, Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development will inform and enlighten both tissue-focused and non-tissue-focused drug development professionals about better use and interpretation of the multidimensional data contained in a tissue biopsy.

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Porth’s Pathophysiology: Concepts of Altered Health States

 Pathology, Physiology  Comments Off on Porth’s Pathophysiology: Concepts of Altered Health States
Jul 032020
 

Succeed in your pathophysiology text with this 9th edition of Porth’s Pathophysiology: Concepts of Altered Health States. Captivating and easy-to understand, this proven book provides comprehensive, nursing-focused coverage designed to help you grasp both the physical and psychological aspects of altered health.
Master the most clinically relevant and difficult to understand disorderswith advanced 3D narrated animations.
Prepare for clinical practice with 14 unit-opening case studies that put a real face on pathophysiology and help you relate the clinical presentation to the underlying pathophysiology.
Master the information you need for success in your career with the unparalleled coverage of disease processes that make this text the most comprehensive pathophysiology text available.
Increase your understanding of key concepts with the full-color art program that illustrates the clinical manifestations of diseases and disease processes.
Find the information you need fast with the book’s consistent presentation of each disease , with detailed coverage of pathophysiology, clinical manifestations, and evaluation and treatment.
Reinforce your understanding of key content with chapter-ending review exercises .
Develop a strong understanding of pathophysiology concepts with the easy-to-follow narrative that builds concepts on one another, defines words as content is presented, and reviews concepts from physiology, biochemistry, physics, and other sciences along the way.
Deepen your understanding by pausing and reviewing salient points using the easily-identified section-opening Objectives and section-ending Summaries.
Retain and apply text information using Key Concepts Boxes help you incorporate key information into a larger conceptual unit, rather than memorizing a string of related and unrelated facts.
Easily access useful references including lists of common suffixes and prefixes, normal laboratory values in both conventional and SI units, and a comprehensive glossary.
Take your understanding beyond the book with anytime, anywhere access to the fully searchable eBook online.

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Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies

 Gastroenterology/Hepatology, Pathology  Comments Off on Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies
Jun 302020
 

Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily “scope-side guide,” it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
More than 1,600 high-quality photomicrographs capture the subtle morphologic spectrum of neoplastic processes of the tubular GI tract. Each image is captioned with key diagnostic considerations and includes call-outs showing subtle features and diagnostic clues.
Practical tools throughout the text include:
Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options o Discussions of how and when to incorporate molecular tools o Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports
Relevant endoscopic images, photographs of select gross specimens, and medical figures
Brief reviews of normal histology that provide contrast to succeeding patterns
“Pearls and Pitfalls” and “Near Misses” sections with lessons from real life sign-out experience
“Frequently Asked Questions” sections that discuss common diagnostic dilemmas
“Sample Note” sections that offer a template of how to synthesize complicated or especially challenging topics
Quizzes in every chapter that provide experience with high-yield, board-style teaching topics
Enhance Your eBook Reading Experience
Read directly on your preferred device(s), such as computer, tablet, or smartphone.
Easily convert to audiobook, powering your content with natural language text-to-speech.

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The Neuropathology of Dementia

 Neurology/Neurosurgery, Pathology  Comments Off on The Neuropathology of Dementia
Jun 242020
 

Completely rewritten and updated, this new edition is almost twice the size of its predecessor. It presents practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes three chapters on neuroimaging, molecular diagnostics, and transgenic models; two chapters on tauopathies under new authorship and a chapter under new authorship on synucleinopathies, including multiple system atrophy.

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Gynecologic and Urologic Pathology: Similarities, Differences and Challenges

 Ob/Gynae, Pathology, Urology  Comments Off on Gynecologic and Urologic Pathology: Similarities, Differences and Challenges
Jun 182020
 

Due to common early development, the pathology of the urogenital tract in males and females present many similarities. Richly illustrated in colour throughout, this essential text evaluates the most common pathologies of the male and female urogenital tract, focussing on similarities, differences, and challenges. Images are colour coded by gender, and feature diagnostic algorithms and boxes highlighting key similarities and differences. This book is intended to bridge the gap between urologic and gynecologic specialties, whose diagnoses are rarely considered or studied together. Understanding common development, similarities and differences is extremely valuable for the evaluation of pathologic features and related dysfunctions. This comprehensive resource will be invaluable to urological and gynaecological pathologists,residents, general pathologists, and for consultants in urology and gynaecology to gain experience in the pathologic diagnostic rationale. This book provides entry to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.

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Pathophysiology: Step By Step Guide for Nursing & NP Students

 Pathology, Physiology  Comments Off on Pathophysiology: Step By Step Guide for Nursing & NP Students
Jun 142020
 

Get familiar with the basic ideas of pathophysiology and keep updated on the latest scientific findings, drugs, and diseases.
Our guide is full of specific and detailed information that will be key to passing your exam. Concepts and principles aren’t simply named or described in passing but explain in detail.
If you are as yet picking up Nursing, Pathophysiology will assist you with acing complex subjects in minutes with unique components found all through the content to make it straightforward and recollect key focuses and data
Inside this guide, you will learn:
• Pathophysiology basics – cellular structure; how cells reproduce, age, and die; adaptive cell changes; the concept of homeostasis and how it affects the body; the causes of disease; and the disease development process
• Infection, cancer, and genetics – the body’s defense mechanisms against infection, types of infective microorganisms and how they invade the body, common infectious disease pathophysiology, classifications of cancer, warning signs of cancer, the cancer metastasis process, the role of genes and chromosomes, how cells divide, and genetic abnormalities
• Cancer as it affects individual body systems – cardiovascular, respiratory, neurologic, gastrointestinal, endocrine, renal system, hematologic, immune, integumentary, sensory, and reproductive system.
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Molecular Pathology in Drug Discovery and Development

 Pathology  Comments Off on Molecular Pathology in Drug Discovery and Development
Jun 142020
 

Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and Development provides an unmatched guide to this cutting-edge discipline and its applications to pharmaceutical science.

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Illustrated Textbook of Cardiovascular Pathology

 Cardiovascular, Pathology  Comments Off on Illustrated Textbook of Cardiovascular Pathology
Jun 142020
 

Cardiovascular diseases have emerged as a major health problem in India and other developing countries. Emphasizing cardiovascular diseases in these areas, the Illustrated Textbook of Cardiovascular Pathology has been compiled for use by residents and consultants in pathology, cardiology, cardiothoracic surgery, and internal medicine. Its simple and systematic approach is easy to read and clearly delineates the disease process. An overview of the normal heart provides a point of reference for further discussion. A straightforward approach to congenital heart disease evaluation using line diagrams helps facilitate and solidify understanding.

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The Liver: Biology and Pathobiology Edition 5

 Pathology  Comments Off on The Liver: Biology and Pathobiology Edition 5
Jun 122020
 

In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology.
Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition&;s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure.
To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com.
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