Neurologic Disease: A Modern Pathophysiologic Approach to Diagnosis and Treatment

 Neurology/Neurosurgery, Pathology, Physiology  Comments Off on Neurologic Disease: A Modern Pathophysiologic Approach to Diagnosis and Treatment
May 302020
 

This novel title explores the central and peripheral nervous system in health and disease.  By first establishing a fundamental basic science knowledge about the cellular elements of the nervous system, the reader is then presented with clinical cases in a pathophysiologic manner, as exemplified in unifying Guillain Barre and Multiple Sclerosis in one chapter on Demyelinating Disease.  The reader is encouraged to adopt a systematic approach of sorting out neurologic problems he or she may face in clinical practice by identifying time and space factors based on the age of a patient.   High quality illustrations for each case are included in the book along with novel three-dimensional reconstructions of MR, PET, and CT data whenever possible. Developed largely for medical students as an introduction to the clinical neurosciences, for neurology residents, and for others doing graduate level neuroscience study, Neurology – A Modern, Pathophysiologic Approach to the Diagnosis and Treatment of Neurologic Disease will also be of significant interest to the established neurologist as a comprehensive, up-to-date reference.
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CURRENT Diagnosis & Treatment Neurology, (Current Diagnosis and Treatment) – 3rd Edition (February 2019 Release)

 Neurology/Neurosurgery  Comments Off on CURRENT Diagnosis & Treatment Neurology, (Current Diagnosis and Treatment) – 3rd Edition (February 2019 Release)
May 282020
 

Practical, up-to-date strategies for assessing and managing the neurologic conditions most frequently seen in adults and children

• Introductory chapters address specific symptoms and diagnostic procedures; subsequent chapters are disease specific and adhere to a standard format, beginning with Essentials of Diagnosis, followed by Clinical Findings, Differential Diagnosis, Treatment, and Prognosis
• Coverage of disorders in both adults and children
• Thorough coverage of diagnostic tests and the very latest pharmacologic treatments
• Practical information on common conditions such as headaches, movement disorders, and central nervous system infections
• Valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic
• Expert help with ischemic and hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, and more
• Each chapter written by experts in that area, without losing readability or coherence

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Clinical Nuclear Medicine Neuroimaging: An Instructional Casebook

 Neurology/Neurosurgery, Radiology  Comments Off on Clinical Nuclear Medicine Neuroimaging: An Instructional Casebook
May 272020
 

This book serves as a casebook for clinical nuclear medicine neuroimaging. Clinical interpretation of nuclear medicine neuroimaging studies is often challenging, mainly due to the complexity of neuroanatomy and a lack of supportive reference books. This is an unmet need in many teaching hospitals. Utilizing a hands-on, case-based approach, this textbook guides readers through clinical nuclear medicine neuroimaging of major neurological diseases and conditions, including dementia, epilepsy, and brain death. Included here are basic guidelines and techniques for nuclear medicine neuroimaging practices, set alongside case examples that include standardized imaging display and detailed interpretation. Each chapter begins with examples of normal brain imaging as a reference point for the remainder of the chapter, which then presents detailed case examples of these diseases through various imaging techniques. Each of the cases highlights clinical and imaging key findings and precise impressions. This is an ideal guide for residents, fellows, and even practicing nuclear medicine physicians as a reference and teaching tool for neuroimaging in clinical nuclear medicine. It will be of significant value to residents, trainees, and young physicians in preparation for their in-service tests and board examinations.
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The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders

 Neurology/Neurosurgery, Psychiatry  Comments Off on The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders
May 262020
 

This book highlights the importance of investigating for ADHD in adults with attention difficulties, poor memory and executive function impairments. The authors advocate a neurodevelopmental assessment approach in all phases of life, and explain how to perform such assessments. The identification of ADHD in adults with other psychiatric and neurological disorders will lead to a better response to treatments, and as a result reduce its social, economic and personal burden.
ADHD can no longer be considered solely a pediatric condition, as it occurs in a significant proportion of adults worldwide. However, ADHD in adults is often unrecognized and untreated. Diagnosing the disorder in adulthood is a challenge, due not only to the different clinical presentation in this phase of life, but also to the fact that other conditions may mask the symptoms. ADHD constitutes a hidden comorbidity with a detrimental impact of those affected, and a poor response (or even non-response) to several treatments.
Intended for psychiatrists, neurologists, specialists in gerontology and neuropsychology, this book is an indispensable resource for all mental health practitioners who want to optimize the treatment of patients affected by psychiatric and neurological disorders who respond poorly to standard treatments.

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https://nitroflare.com/view/D61FFAAE789FCA2/3030390500.epub

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Neurotropic Viral Infections: Volume 1: Neurotropic RNA Viruses

 Infectious Diseases, Microbiology, Neurology/Neurosurgery  Comments Off on Neurotropic Viral Infections: Volume 1: Neurotropic RNA Viruses
May 252020
 

This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities).
Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes.  Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to polio to West Nile.
Volume 2, Neurotropic Retroviruses, DNA Viruses, Immunity and Transmission, includes 15 chapters divided into two parts.  Part 1 includes 7 chapters on retroviruses and DNA viruses that cause human disease of the central nervous system ranging from HIV to varicella zoster virus.  Part 2 includes chapters on transmission of these viruses by transplantation, bites by bats and insects, clinical management of the infections, and beneficial uses of attenuated viruses.
Neurotropic Viral Infections is a unique resource, bridging basic, clinical, and translational approaches.​

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https://nitroflare.com/view/77127939AEBC5E8/Neurotropic_Viral_Infections_Volume_1_Neurotropic_RNA_Viru.pdf

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May 242020
 

This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.
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Alzheimer’s Disease and Infectious Causes: The Theory and Evidence (McFarland Health Topics)

 Infectious Diseases, Neurology/Neurosurgery  Comments Off on Alzheimer’s Disease and Infectious Causes: The Theory and Evidence (McFarland Health Topics)
May 242020
 

With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer’s disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer’s disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer’s patients.

Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer’s disease. Sources of infection in Alzheimer’s disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer’s disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer’s disease

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https://nitroflare.com/view/3F3C445BF2080B3/Alzheimers_Disease_and_Infectious_Causes_-_Elaine_A._Moore.epub

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BACE: Lead Target for Orchestrated Therapy of Alzheimer’s Disease

 Neurology/Neurosurgery  Comments Off on BACE: Lead Target for Orchestrated Therapy of Alzheimer’s Disease
May 202020
 

BACE inhibitors and their use in the treatment of Alzheimer’s Disease
BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer’s Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer’s Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery.
This book details the story of the discovery of BACE and its role in AD and comprehensively discusses:
The development of BACE inhibitors as therapeutics for Alzheimer’s disease
The research that led to the identification of BACE
New BACE inhibitors currently being clinically tested
ADME (absorption, distribution, metabolism, excretion) and clinical trial design―topics not addressed in current field literature
Cutting-edge technology such as high-throughput screening, structure-based drug design, and QSAR in context of BACE inhibitors and Alzheimer’s drug discovery
Other approaches to BACE inhibition based on interaction with the precursor protein APP
By enhancing the reader’s understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer’s research―and inspire new approaches to treatment of AD.

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https://nitroflare.com/view/8E3CF3E3893C852/047029342X.pdf

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Advances in Translational Neuroscience of Eye Movement Disorders

 Neurology/Neurosurgery, Ophthalmology  Comments Off on Advances in Translational Neuroscience of Eye Movement Disorders
May 202020
 

A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson – one of the pioneers of contemporary ocular motor and vestibular neuroscience.

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https://nitroflare.com/view/26F84469D561456/3030314065.epub

https://nitroflare.com/view/51B21E3742592C3/3030314065.pdf

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Complications in Neurosurgery

 Neurology/Neurosurgery  Comments Off on Complications in Neurosurgery
May 202020
 

Learn from key leaders in the field of neurosurgery with the practical guidance presented in this first-of-its-kind resource. Complications in Neurosurgery uses a case-based format to explore complications across the full range of commonly performed neurosurgical procedures. As you review dozens of up-to-date, real-life cases, you’ll become better equipped to identify pitfalls ahead of time and have the knowledge to handle difficult situations that arise during surgery.

  • Presents commonly encountered cases provided by experienced neurosurgeons in all areas of this challenging specialty.
  • Includes high-quality photographs, images, and dynamic video to ensure complete visual understanding of the procedures.
  • Uses a consistent, easy-to-read format throughout, covering a wide range of surgeries including general neurosurgery and cranial complications, as well as spinal and peripheral complications.
  • Numerous videos depict possible complications for each type of surgery; for example, Complications of Cerebral Bypass Surgery includes videos showing how to obtain venous hemostasis without risking injury to the STA, how to manage atheroma within the donor vessel, and how to manage intraoperative occlusion of the bypass.

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http://nitroflare.com/view/33152DD2A54A80B/0323509614.pdf

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