Diastolic Heart Failure

 Cardiovascular  Comments Off on Diastolic Heart Failure
Nov 202019
 

Heart failure is the biggest killer in the western world, and the prevalence is expected to increase due to aging of the population. Over the past decade there has been an increasing awareness of left ventricular (LV) diastolic dysfunction as a mechanism of congestive heart failure. This book provides the clinician with essential insights into the epidemiology and aetiology of diastolic heart failure, and will enable them to understand how the condition can be diagnosed. Furthermore, the book will provide insights in cardiac function that are needed to perform and interpret the diagnostic tests, and to provide some guides to treatment choices.
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Oxidative Stress in Heart Diseases

 Cardiovascular  Comments Off on Oxidative Stress in Heart Diseases
Nov 202019
 

This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

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Societal Impact of Headache: Burden, Costs and Response

 Neurology/Neurosurgery  Comments Off on Societal Impact of Headache: Burden, Costs and Response
Nov 202019
 

This volume describes the impact of headache disorders on public health, and their adverse consequences for society. It opens with an overview of relevant headache disorders before describing, qualitatively, how the burdens attributable to these disorders fall upon adults, adolescents and children.
In the second section, beginning with a methodological introduction discussing the principles and potential pitfalls of epidemiological studies assessing prevalence, headache-attributed burden and functional impact, the burdens of headache including financial cost are examined quantitatively and in detail. The third section critically reviews society’s response, its inadequacies and the scope for improvement. Topics here include the political failure to recognize the public ill-health and cost that are the consequences of inadequate headache care; the role of the WHO in addressing the problem; headache service organization, delivery and quality; and the effectiveness and cost-effectiveness of interventions. The book closes by considering the way forward. This volume contains important messages for primary care and is likely to be of even greater interest to headache specialists and those concerned with public health and health policy.

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https://nitroflare.com/view/4DA85A557233F30/3030247260.pdf

https://nitroflare.com/view/6D3C7769B992B14/3030247260.epub

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Contrast Media: Safety Issues and ESUR Guidelines Ed 2

 Radiology  Comments Off on Contrast Media: Safety Issues and ESUR Guidelines Ed 2
Nov 202019
 

Two years only after the publication of the ? rst edition of “Contrast media – Safety issues and ESUR guidelines” in our book series Medical Radiology in 2006, it appeared that a second edition was urgently needed. The ? rst edition was indeed an exceptional success with our readership and sold out rapidly, but moreover the safety of MR contrast media urgently required a reappraisal after the publication of a new and dramatic adverse reaction to some of the gadolini- based agents: the so called NSF syndrome. I am very much indebted to Professor Henrik S. Thomsen and his academic colleagues from the ESUR Contrast Medium Safety Committee for accepting the task to prepare a second edition of their remarkable book.Within a record short period of time they have been able to complete this fully revised new volume. It offers to the readers a comprehensive overview of all problems related to the use of contrast media in modern radiology and of our latest knowledge and insights in the mechanisms of adverse reactions related to contrast media. It answers all questions that radiologists and referring physicians are confronted with in their daily practice when they consider the administration of these agents to their patients.
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Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education Second Edition Edition 2

 Miscellaneous  Comments Off on Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education Second Edition Edition 2
Nov 192019
 

This book is written to help clinical and basic researchers, as well as graduate students, in the understanding of hemodynamics. Recent developments in genetics and molecular biology as well as new non-invasive measurement techniques, make it possible to measure and understand the hemodynamics of heart and vessels better than ever before. Hemodynamics make it possible to characterize, in a quantitative way, the function of the heart and the arterial system, thereby producing information about what genetic and molecular processes are of importance for cardiovascular function. The layout of the book provides a short and essential overview of individual topics. It is designed as a quick reference guide and each chapter can stand alone. The chapters are written to define the basic and applied principles of the hemodynamic topic. If more details or broader perspectives are desired, the reader can refer to related chapters to which the text refers, or the textbooks listed in the `Reference books` section in Appendix 5. Each chapter starts with a `box` containing a figure and caption that give the basic aspects of each topic. Chapters end with the section, `Physiological and Clinical Relevance` that puts the information from the chapter into perspective. The section in between, `Description` can be used to get more detailed information and find relevant references.
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Space Pharmacology

 Pharmacology  Comments Off on Space Pharmacology
Nov 192019
 

“Space Pharmacology” is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each major physiological system in turn. Every section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussion looking forward to the new medical challenges we are likely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown.
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Neuropsychology of Everyday Functioning

 Neurology/Neurosurgery  Comments Off on Neuropsychology of Everyday Functioning
Nov 192019
 

While neuropsychological testing can accurately detect cognitive deficits in persons with brain injury, the ability to reliably predict how these individuals will function in everyday life has remained elusive. This authoritative volume brings together well-known experts to present recent advances in the neuropsychological assessment of key real-world capacities: the ability to live independently, work, manage medications, and drive a car. For each of these domains, contributors describe cutting-edge tests, procedures, and interpretive strategies and examine salient theoretical and methodological issues. Chapters also review approaches for evaluating specific populations, including older adults and patients with traumatic brain injury, depression, dementia, schizophrenia, and other neurological and psychiatric disorders.
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Pathology of Challenging Melanocytic Neoplasms: Diagnosis and Management

 Pathology  Comments Off on Pathology of Challenging Melanocytic Neoplasms: Diagnosis and Management
Nov 192019
 

Melanocytic neoplasms are of capital importance for all surgical pathologists and dermatopathologists. These tumors span a huge range of morphologic expression and biologic behavior, are potentially of the highest medical significance and are often fraught with diagnostic pitfalls and high litigation risk.
Pathology of Challenging Melanocytic Neoplasms offers a dynamic text where readers will encounter a broad spectrum of challenging melanocytic lesions, both benign and malignant and will thereby acquire a solid, working knowledge that they can immediately apply to daily diagnosis. The authors aim to clarify this often thorny field, keeping a steady focus on patient-related issues. The volume emphasizes the practical application of basic morphologic principles, immunohistochemistry and molecular methods in order to secure a confident diagnosis. Abundant illustrations display the characteristic features of the most important disease entities.
Rather than being yet another encyclopedic work of reference, this volume takes a fresh approach as it resembles a series of stimulating seminars employing exemplary case material to highlight, illustrate, and succinctly discuss the key points. To this end, the reader will be guided through a series of paired cases that pose a significant diagnostic challenge. By comprehensively comparing and contrasting two related entities, each such chapter will illuminate an intellectual pathway through which an important diagnostic puzzle can be solved. To broaden the differential diagnosis even further, additional illustrative cases are added to each discussion. Algorithms and tables summarize key points. Clinically relevant, up-to-date references will be provided to guide further study. Written by experts in the field, this novel text will be of great value to surgical pathologists in practice and dermatologists as well as residents and fellows training in these specialties.

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Rapid Detection of Infectious Agents (Infectious Agents and Pathogenesis)

 Infectious Diseases, Pathology  Comments Off on Rapid Detection of Infectious Agents (Infectious Agents and Pathogenesis)
Nov 192019
 

Busy clinicians and health practitioners recognize the importance of speedy detection of pathogens to impede the further spread of infection, and to ensure their patients’ rapid and complete recovery. This reader-friendly reference is a unique collection of the newest and most effective diagnostic techniques currently in use in clinical and research laboratories. Instructive commentary regarding the application of these often complex methods is provided. This essential text aids readers in selecting the most efficient method, finding the necessary resources, and avoiding the most common pitfalls in implementation.
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Cardiac Pathology: A Guide to Current Practice Edition 2

 Cardiovascular, Pathology  Comments Off on Cardiac Pathology: A Guide to Current Practice Edition 2
Nov 192019
 

This updated second edition provides a comprehensive overview of cardiac pathology. Clear illustrations of the common styles of dissection are provided along with the normal anatomy and histology. The chapters cover autopsy heart examination, ischemic heart disease, myocarditis, sudden death, valvular disease, transplant pathology, cardiomyopathy, cardiac neoplasia and congenital heart disease with a clear analysis of diagnostic criteria (macroscopic, microscopic and genetic) for both common cardiac diseases and those of less common types. The text is accompanied by high quality macroscopic and microscopic images and references to other specialty data sources.
Cardiac Pathology: A Guide to Current Practice is aimed at established pathologists and trainees, as well as any clinician with an interest in cardiac disease. It will be of value to those working in cardiac surgery, cardiology and those in the autopsy/forensic fields.

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