Category Archives: Oncology

Gene Therapy of Cancer: Methods and Protocols

Despite various difficulties, the field of gene therapy, particularly with regard to cancer, has accumulated a tremendous amount of vital pre-clinical and clinical data. Gene Therapy of Cancer: Methods and Protocols, Second Edition fully updates the first edition with expert coverage of established and novel protocols involving both experimental and clinical approaches to cancer gene therapy. This state-of-the-art volume contains overviews of new concepts and strategies with chapters on regulatory and ethical issues, developments, problems and possible limitations of design and production of gene therapeutics as well as translational issues. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Cutting edge and authoritative, Gene Therapy of Cancer: Methods and Protocols, Second Edition is an ideal guide for all those who wish to explore the fast-paced and critical study of nonviral, viral, experimental and clinical cancer gene therapy.
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Gene Therapy of Solid Cancers: Methods and Protocols

This volume provides insight into recent developments on experimental and clinical strategies for cancer gene therapy. Gene Therapy of Solid Cancers: Methods and Protocols guides readers through protocols on gene therapeutic strategies in combination with helpful technical notes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Concise and easy-to-use, Gene Therapy of Solid Cancers: Methods and Protocols aims to ensure successful results in the further study of this vital field.


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Cancer: The Metabolic Disease Unravelled (Curing Cancer)

Never Fear Cancer Again

What if I told you that all the research needed to end the disease of cancer forever has already been completed? Would you believe it? Well now you don’t have to!

Cancer: The Metabolic Disease Unravelled is your complete guide to the revolutionary scientific discoveries made over the past 150 years that reveal exactly what cancer is, what cancer isn’t, and the most efficient ways to heal it – without causing patients any harm whatsoever in the process.
Bestselling author Mark Sloan lost his mother to cancer when he was 12 years old and now he’s made it his life mission to ensure that no child has to go through what he did, ever again.
Backed by evidence from over 1900 scientific and clinical references, Cancer: The Metabolic Disease Unravelled explodes the myth that cancer is a disease of genetic origin, and reveals its true and entirely reversible cause: a dysfunctional metabolism.
In Cancer: The Metabolic Disease Unravelled, you’ll discover:

  • The single most important scientific cancer discovery ever made
  • How The Cancer Genome Atlas Project proved that cancer is a metabolic disease
  • The single most powerful dietary change you can make to prevent cancer
  • At least 5 effective alternative cancer therapies and testimonials from people who’ve used them to heal

Cancer: The Metabolic Disease Unravelled is your ultimate guide to understanding what cancer is, what cancer isn’t, and how to prevent and reverse it quickly and inexpensively without causing any harm whatsoever in the process.


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Cure Cancer Naturally: A step by step guide on how to beat cancer naturally using diet and the best herbs

Cure Cancer NaturallyA step by step guide on how to beat cancer naturally using diet and the best herbs
Cancer, of all chronic illnesses, is the most curable. Today, the goal is not only to preserve the best life that could be wished for in the past but to cure the disease patient.
Everyone cannot defeat cancer. Some people are likely to succumb to it. If you try to combat it, however, you have a chance of beating it.
This book is not written to delight or lecture. It is composed as briefly as possible by a layperson in layman’s language to help the person with cancer have the best possible opportunity to beat it.
The only function in composing this book is to see that you have the very best chance of defeating cancer as quickly as possible.
Absolutely nothing is put in this book to fill the area. You obtained it to aid you in dealing with cancer cells, not to maintain your hectic reading. It is not feasible to emphasize enough how essential every item revealed is to the assurance of recovery. Don’t rationalize that little product can be overlooked without jeopardizing your opportunities for healing. That single variable that you have never come across and most likely question the validity of and may feel like an annoyance can be the secret to healing. Let me guarantee you that each idea has been stemmed by a person apart from me. They have been talked about over as well as over by many individuals. They have been attempted by countless cancer cells people before you and are thought to be a favorable recovery factor. Also, nothing included herein is believed to have any downside risk. Many other points could have been put in; however, it might pose a potential danger. It is thought that absolutely nothing in this book has any adverse opportunity if properly applied.
As the author of this book, I believe that this book will be an indispensable reference and trusted guide for you who may want to reuse the information of the original text or passage naturally.


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Oral Cancer Research Advances

Oral cancer is any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighbouring anatomic structure, such as the nasal cavity or the maxillary sinus. This book presents important research from around the world.


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Computational Systems Biology of Cancer

The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models―integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools.

Novel Approaches to Fighting Cancer
Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie (Paris, France), Computational Systems Biology of Cancer explains how to apply computational systems biology approaches to cancer research. The authors provide proven techniques and tools for cancer bioinformatics and systems biology research.

Effectively Use Algorithmic Methods and Bioinformatics Tools in Real Biological Applications
Suitable for readers in both the computational and life sciences, this self-contained guide assumes very limited background in biology, mathematics, and computer science. It explores how computational systems biology can help fight cancer in three essential aspects:

– Categorising tumours

– Finding new targets

– Designing improved and tailored therapeutic strategies

Each chapter introduces a problem, presents applicable concepts and state-of-the-art methods, describes existing tools, illustrates applications using real cases, lists publically available data and software, and includes references to further reading. Some chapters also contain exercises. Figures from the text and scripts/data for reproducing a breast cancer data analysis are available at


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Neuro-Oncology – Neurosurgical Operative Atlas 2nd Edition

Part of the Neurosurgical Operative Atlas series, this volume presents contemporary operative procedures in neuro-oncology. It offers an accessible, step-by-step guide to the latest treatments and considerations in neuro-oncology, with extended coverage of every stage of each procedure, from patient selection, to preoperative planning, to operative techniques and post-operative management. You are provided with the most informed perspectives in the field as contributors discuss the techniques which they have themselves developed or mastered as experts in the field. Abundant artwork, much of it in full color, supplements the text and highlights critical points, making this book an exceptional clinical resource.
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Principles and Practice of Surgical Oncology

Principles and Practice of Surgical Oncology uniquely emphasizes a multidisciplinary, integrated approach to the treatment of solid tumors. It presents treatment strategies that combine surgery with preoperative or postoperative adjunctive chemotherapy, hormonal therapy, and/or radiation therapy to achieve optimal outcome. The book features contributions from surgeons, basic scientists, pathologists, radiologists, radiation therapists, and medical oncologists and offers a comprehensive presentation of genetics, molecular biology, pathogenesis, and multimodal therapeutic approaches. A unique feature of the book is a commentary following each chapter, which describes alternative approaches and discusses controversial areas of current therapy.


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MRI Manual of Pelvic Cancer, Second Edition

Written by internationally renowned authors, this title is an invaluable reference for all those required to report on MR examinations, with accurate cancer staging aided by the extensive use of high quality MR images of pelvic cancer.
Each chapter gives a short account of every disease and a set of images demonstrating the tumour, node and metastasis stages, based on the 2010 UICC/AJCC staging system.

A highly useful resource, this guide also:

Introduces pelvic cancer staging, MRI technique, and pelvic anatomy

Presents a comprehensive set of state-of-the-art images of the various pelvic cancers

Contains illustrations of recurrent disease and appearances following chemo-radiotherapy

Discusses imaging before exenterative surgery and the imaging of metastatic disease within the pelvis

What’s new to this edition:

New techniques in a number of pelvic cancers, including cervical, endometrial, ovarian and vaginal cancer, such as MR diffusion, MR spectroscopy and Dynamic Contrast Imaging

Image findings post chemoradiation for cervical, rectal and bladder cancer

New section on image findings in brachytherapy for prostate cancer

Brand new chapter on penile cancer

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STAT Inhibitors in Cancer

This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.
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