Toxicology’s gold-standard text – completely updated to reflect the latest breakthroughs and discoveries
A Doody’s Core Title for 2021!
Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere.
Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition is logically divided into seven sections:
- General Principles of Toxicology
- Disposition of Toxicants
- Non-Organ Directed Toxicity
- Target Organ Toxicity
- Toxic Agents
- Environmental Toxicology
- Applications of Toxicology
Many new contributors capture the progress made in toxicology over the past few years:
This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous contributions to the book.
Sharing their expertise, they deliver dynamic new coverage of the importance of apoptosis, autophagy, cytokines, growth factors, oncogenes, cell cycling, receptors, gene regulation, protective mechanisms, repair mechanisms, transcription factors, signaling pathways, transgenic mice, knock-out mice, humanized mice, polymorphisms, microarray technology, second-generation sequencing, genomics, proteomics, epigenetics, exposome, microbiota, read across, adverse outcome pathways, high-content screening, computational toxicology, innovative test methods, and organ-on-a-chip in understanding the mechanisms of toxicity and the regulation of chemicals.
A true “essential”
If you are in need of an up-to-date, all-in-one overview of the biomedical and environmental aspects of toxicology – written by experts, and presented in full color, your search ends here.
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Expanded, revamped and completely revised with recent advances and current developments. Includes five major parts with 40 concise chapters as well as appendices and index covering over 600 pages. Contains around 700 excellent original coloured photographs and over 500 plain drawings, charts, tables and boxes.
This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil.
This book reviews the history, regulatory status, pharmacopeial specifications, and harmonization of pharmaceutical excipients in the United States and Europe, and provides a comprehensive understanding of the current scientific basis for safety evaluation and risk assessment.
Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary
This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil.