Casarett & Doull’s Toxicology: The Basic Science of Poisons, 9th Edition

 Toxicology  Comments Off on Casarett & Doull’s Toxicology: The Basic Science of Poisons, 9th Edition
Feb 072022
 

Toxicology’s gold-standard text – completely updated to reflect the latest breakthroughs and discoveries 

A Doody’s Core Title for 2021! 

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere.

 

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition is logically divided into seven sections:

 

  • General Principles of Toxicology
  • Disposition of Toxicants
  • Non-Organ Directed Toxicity
  • Target Organ Toxicity
  • Toxic Agents
  • Environmental Toxicology
  • Applications of Toxicology

 

 

Many new contributors capture the progress made in toxicology over the past few years:
This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous contributions to the book.

Sharing their expertise, they deliver dynamic new coverage of the importance of apoptosis, autophagy, cytokines, growth factors, oncogenes, cell cycling, receptors, gene regulation, protective mechanisms, repair mechanisms, transcription factors, signaling pathways, transgenic mice, knock-out mice, humanized mice, polymorphisms, microarray technology, second-generation sequencing, genomics, proteomics, epigenetics, exposome, microbiota, read across, adverse outcome pathways, high-content screening, computational toxicology, innovative test methods, and organ-on-a-chip in understanding the mechanisms of toxicity and the regulation of chemicals.

A true “essential”
If you are in need of an up-to-date, all-in-one overview of the biomedical and environmental aspects of toxicology – written by experts, and presented in full color, your search ends here.

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Textbook of Forensic Medicine and Toxicology 2nd ed. Edition

 Forensic Medicine, Toxicology  Comments Off on Textbook of Forensic Medicine and Toxicology 2nd ed. Edition
Feb 062022
 

Expanded, revamped and completely revised with recent advances and current developments. Includes five major parts with 40 concise chapters as well as appendices and index covering over 600 pages. Contains around 700 excellent original coloured photographs and over 500 plain drawings, charts, tables and boxes.

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Forensic Toxicology: Drug Use and Misuse 1st Edition

 Forensic Medicine, Pharmacology, Toxicology  Comments Off on Forensic Toxicology: Drug Use and Misuse 1st Edition
Jan 042022
 

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies.
The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects.
From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.
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Textbook of Forensic Medicine & Toxicology 18th/2017

 Forensic Medicine, Toxicology  Comments Off on Textbook of Forensic Medicine & Toxicology 18th/2017
Sep 142021
 

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Pharmacokinetics and Toxicokinetics 1st Edition

 Pharmacology, Toxicology  Comments Off on Pharmacokinetics and Toxicokinetics 1st Edition
Aug 212021
 

Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach.

 

 

 

The book presents mathematical descriptions of physiological processes employed in different approaches to PK/TK modeling. It focuses on emphasizing general principles and concepts, rather than isolated observations. Above all, the book is an effort to blend the pharmaceutical and toxicological aspects of both fields.

 

 

 

The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advance courses and seminars. This is an invaluable resource for scientists in the pharmaceutical sciences, clinical sciences, and environmental health sciences, as well as those involved in drug discovery and development.

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Toxicological Chemistry and Biochemistry (Toxicological Chemistry & Biochemistry) 3rd Edition

 Biochemistry, Toxicology  Comments Off on Toxicological Chemistry and Biochemistry (Toxicological Chemistry & Biochemistry) 3rd Edition
Aug 182021
 

This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil.

The new chapter on toxic effects considers toxicities to the endocrine and reproductive systems, and the section on xenobiotics analysis deals with the determination of toxicants and their metabolites in blood and other biological materials. The chapter on the genetic aspects of toxicology discusses the ways in which chemical damage to DNA can cause mutations, cancer, and other toxic effects on specific body systems, and it considers the role of genetics in determining individual susceptibilities to various toxicants.

Toxicological Chemistry and Biochemistry, Third Edition retains the basic information and structure that made the first two editions popular with students and industry professionals, while enhancing the usefulness of the book and modernizing it in important areas. Review questions and supplementary references at the end of each chapter round out the third edition of this bestselling work.

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Excipient Toxicity and Safety (Drugs and the Pharmaceutical Sciences) 1st Edition

 Pharmacology, Toxicology  Comments Off on Excipient Toxicity and Safety (Drugs and the Pharmaceutical Sciences) 1st Edition
Aug 112021
 

This book reviews the history, regulatory status, pharmacopeial specifications, and harmonization of pharmaceutical excipients in the United States and Europe, and provides a comprehensive understanding of the current scientific basis for safety evaluation and risk assessment.
Examines excipients as a unique class of products and explores new procedures for determining toxicity!
A timely and unique addition to the pharmaceutical literature, containing over 570 citations that support and enhance the text, Excipient Toxicity and Safety

  • identifies the differences between excipients (inactive ingredients), food ingredients, and drug products
  • evaluates issues of dose administration, species selection, and study design for various routes of exposure
  • provides detailed information on the historical uses of excipients in drug formulations
  • clarifies the Safety Committee of the International Pharmaceutical Excipients Council’s (IPEC) guidelines and technical specifications for conducting tests for each route of exposure
  • explains how data generated in toxicity models are applied to identify hazards in drug formulations
  • details exposure assessment to link hazard identification with risk
  • considers the requirements and importance of purity specifications
  • and much more!
    Excipient Toxicity and Safety is a blue-ribbon reference ideal for pharmacists; toxicologists; pharmacologists; analytical chemists; quality control, quality assurance, and regulatory compliance managers; and upper-level undergraduate and graduate students in these disciplines.

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Casarett & Doull’s Essentials of Toxicology, Third Edition (Lange) 3rd Edition

 Toxicology  Comments Off on Casarett & Doull’s Essentials of Toxicology, Third Edition (Lange) 3rd Edition
Aug 042021
 

Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary

A Doody’s Core Title for 2017!

Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the major principles and concepts that were presented in depth in Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition, the field’s gold-standard text.

Presented in full color, the book concisely describes the science of toxicology, and includes important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems. A summary of key points at the beginning and review questions at the end of each chapter help you study, understand, and memorize the material.

Reflecting the expertise of more than sixty renowned contributors, Casarett & Doull’s Essentials of Toxicology is logically divided into seven sections:

Succinct and comprehensive, there is no better text for gaining an understanding of essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents than Casarett & Doull’s Essentials of Toxicology.

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Pharmacokinetics and Toxicokinetics 1st Edition

 Pharmacology, Toxicology  Comments Off on Pharmacokinetics and Toxicokinetics 1st Edition
Jun 102021
 

Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach.

 

 

 

The book presents mathematical descriptions of physiological processes employed in different approaches to PK/TK modeling. It focuses on emphasizing general principles and concepts, rather than isolated observations. Above all, the book is an effort to blend the pharmaceutical and toxicological aspects of both fields.

 

 

 

The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advance courses and seminars. This is an invaluable resource for scientists in the pharmaceutical sciences, clinical sciences, and environmental health sciences, as well as those involved in drug discovery and development.

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Toxicological Chemistry and Biochemistry (Toxicological Chemistry & Biochemistry) 3rd Edition

 Biochemistry, Toxicology  Comments Off on Toxicological Chemistry and Biochemistry (Toxicological Chemistry & Biochemistry) 3rd Edition
Jun 102021
 

This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil.

The new chapter on toxic effects considers toxicities to the endocrine and reproductive systems, and the section on xenobiotics analysis deals with the determination of toxicants and their metabolites in blood and other biological materials. The chapter on the genetic aspects of toxicology discusses the ways in which chemical damage to DNA can cause mutations, cancer, and other toxic effects on specific body systems, and it considers the role of genetics in determining individual susceptibilities to various toxicants.

Toxicological Chemistry and Biochemistry, Third Edition retains the basic information and structure that made the first two editions popular with students and industry professionals, while enhancing the usefulness of the book and modernizing it in important areas. Review questions and supplementary references at the end of each chapter round out the third edition of this bestselling work.

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