The Benefits of Natural Products for Neurodegenerative Diseases

 Neurology/Neurosurgery  Comments Off on The Benefits of Natural Products for Neurodegenerative Diseases
Oct 302019
 

Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.

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Central Nervous System Intraoperative Cytopathology

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Oct 292019
 

This book covers the full spectrum of benign and malignant conditions of the central nervous system with an emphasis on common disorders. It contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities.
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Neuropeptide Systems as Targets for Parasite and Pest Control

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Oct 272019
 

The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also plagued by invertebrate parasites. The deployment of chemical agents for these purposes inevitably elicits the selection of resistant populations of the targets of control, necessitating a regular introduction of new kinds of molecules. Experience in other areas of chemotherapy has shown that a thorough understanding of the biology of disease is an essential platform upon which to build a discovery program. Unfortunately, investment of research resources into understanding the basic physiology of invertebrates as a strategy to illuminate new molecular targets for pesticide and parasiticide discovery has been scarce, and the pace of introduction of new molecules for these indications has been slowed as a result. An exciting and so far unexploited area to explore in this regard is invertebrate neuropeptide physiology. This book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems.
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Functional Brain Tumor Imaging

 Neurology/Neurosurgery, Radiology  Comments Off on Functional Brain Tumor Imaging
Oct 272019
 

This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Imaging of Brain Tumors is a unique resource that serves to advance patient care and research in this rapidly developing field.
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Pathological Potential of Neuroglia: Possible New Targets for Medical Intervention

 Neurology/Neurosurgery, Pathology  Comments Off on Pathological Potential of Neuroglia: Possible New Targets for Medical Intervention
Oct 272019
 


Pathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process.

The brain homeostasis, which lies at the fulcrum of healthy brain function, the compromise of which invariably results in dysfunction/disease, however, is entirely controlled by neuroglia. It is becoming clear that neuroglial cells are involved in various aspects of initiation, progression and resolution of neuropathology. In this book we aim to integrate the body of information that has accumulated in recent years revealing the active role of glia in such pathophysiological processes. Understanding roles of glial cells in pathology will provide new targets for medical intervention and aide the development of much needed therapeutics. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry.

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Organism Models of Autism Spectrum Disorders (Neuromethods)

 Neurology/Neurosurgery, Uncategorized  Comments Off on Organism Models of Autism Spectrum Disorders (Neuromethods)
Oct 272019
 

As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab.

Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.

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Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches

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Oct 252019
 

One of the most common problems for spinal cord injury patients is urinary system dysfunction. The book Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches introduces how to solve this problem using multi-disciplinary approaches. From animal model studies to surgical techniques as well as successful case reports, six kinds of surgery are presented in separate chapters. This up-to-date monograph will be a valuable resource for surgeons, urologists and neurologists caring for spinal cord injury patients. The contributors are a group of surgeons working in the fields of orthopaedics and microsurgery. Editor Chunlin Hou is Professor in Changzheng Hospital, the Second Military Medical University, Shanghai, China.
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Neuroscience of Cognitive Development: The Role of Experience and the Developing Brain

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Oct 252019
 

A new understanding of cognitive development from the perspective of neuroscience
This book provides a state-of-the-art understanding of the neural bases of cognitive development. Although the field of developmental cognitive neuroscience is still in its infancy, the authors effectively demonstrate that our understanding of cognitive development is and will be vastly improved as the mechanisms underlying development are elucidated.
The authors begin by establishing the value of considering neuroscience in order to understand child development and then provide an overview of brain development. They include a critical discussion of experience-dependent changes in the brain. The authors explore whether the mechanisms underlying developmental plasticity differ from those underlying adult plasticity, and more fundamentally, what distinguishes plasticity from development.

Having armed the reader with key neuroscience basics, the book begins its examination of the neural bases of cognitive development by examining the methods employed by professionals in developmental cognitive neuroscience. Following a brief historical overview, the authors discuss behavioral, anatomic, metabolic, and electrophysiological methods. Finally, the book explores specific content areas, focusing on those areas where there is a significant body of knowledge on the neural underpinnings of cognitive development, including:
* Declarative and non-declarative memory and learning
* Spatial cognition
* Object recognition
* Social cognition
* Speech and language development
* Attention development

For cognitive and developmental psychologists, as well as students in developmental psychology, neuroscience, and cognitive development, the authors’ view of behavioral development from the perspective of neuroscience sheds new light on the mechanisms that underlie how the brain functions and how a child learns and behaves.

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Invariants of Behavior: Constancy and Variability in Neural Systems

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Oct 232019
 

The study of the brain and behavior is illuminated with the discovery of invariances.
Experimental brain research uncovers constancies amidst variation, with respect to interventions and transformations prescribed by experimental paradigms.
Place cells, mirror neurons, event related potentials and areas differentially active in fMRI, all illustrate the pervasive role of invariances in neural systems in relation to their function.

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Dementia in Clinical Practice: A Neurological Perspective: Pragmatic Studies in the Cognitive Function Clinic Edition 2

 Neurology/Neurosurgery  Comments Off on Dementia in Clinical Practice: A Neurological Perspective: Pragmatic Studies in the Cognitive Function Clinic Edition 2
Oct 232019
 

This concise, pragmatic, pocket-sized book addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in a dedicated neurological dementia clinic.
It covers the use of cognitive and non-cognitive screening instruments and their diagnostic utility and the use of other diagnostic investigations: neuroimaging, neurophysiology and neuropathology. The diagnostic mix is discussed in terms of both neuropsychological syndromes and neurological diagnoses, as is the use of conventional treatments for dementia and the impact of national directives (e.g. NICE, National Dementia Strategy) on day-to-day clinical practice.
Dementia in Clinical Practice: A Neurological Perspective, Second Edition is an illustrated, practical resource for medical professionals involved in the assessment and management of dementia patients. It is of particular benefit to neurologists, psychiatrists, geriatricians, primary care practitioners and those working in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.

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