Color Atlas of Pharmacology 5th Edition

 Pharmacology  Comments Off on Color Atlas of Pharmacology 5th Edition
Nov 292019
 

The Fifth Edition of Luellmann’s Color Atlas of Pharmacology has been extensively revised to include all recent advances and new drugs, and the illustrations have been optimized and updated. Each two-page spread presents concise text on the left complemented by detailed full-color illustrations on the right to help users quickly digest important facts and concepts.

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Radiopharmaceuticals: A Guide to PET/CT and PET/MRI 2nd Edition

 Pharmacology, Radiology  Comments Off on Radiopharmaceuticals: A Guide to PET/CT and PET/MRI 2nd Edition
Nov 282019
 

This book provides a rapid and concise guide to PET (PET/CT and PET/MRI) molecular imaging, concentrating extensive information on PET radiopharmaceuticals in a single volume.
The book reflects the rapid development of several PET tracers over the last decade, as a result of which the “traditional” PET/CT with 18F-FDG, the “cornerstone” of PET imaging, is now only one of several available options, which use different tracers for different diseases. For the same reason, PET imaging is no longer limited to the field of oncology.

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Pharmaceutical Powder Compaction Technology

 Pharmacology  Comments Off on Pharmaceutical Powder Compaction Technology
Nov 242019
 

Compaction of powder constituents―both active ingredient and excipients―is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application.

This unique reference covers:

– The physical structure of pharmaceutical compacts

– Bonding phenomena that occur during powder compaction

– Compression mechanisms of pharmaceutical particles

– Theories and basic principles of powder compaction

New topics include:

– Compaction data analysis techniques

– The migration of powder constituents into commercial manufacture

– Instrumentation for compaction

– Compaction functionality testing, which is likely to become a USP requirement

– Design space for compaction

– Metrics required for scalability in tablet compression

– Interactive compaction and preformulation database for commonly used excipients

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Handbook of Pharmaceutical Excipients Ed 8

 Pharmacology  Comments Off on Handbook of Pharmaceutical Excipients Ed 8
Nov 232019
 

The Handbook of Pharmaceutical Excipients collects together essential data on the physical properties of excipients as well as providing information on their safe use and applications. All of the 400+ monographs are also thoroughly cross-referenced and indexed to allow their identification by chemical, non-proprietary or trade names. It is internationally recognised as the authoritative source of information on pharmaceutical excipients and a comprehensive guide to uses, properties and safety.

Monographs benefit from a standardized, easy-to-use template and include:
Pharmacopeial information from the UK, Europe, Japan and the United States where relevant
Non-proprietary names and synonyms
Chemical name, CAS Registry number, empirical formula, molecular weight
Functional category, applications and incompatibilities
Material description and typical properties
Safety, stability, storage and handling information
Method of manufacture
Related substances
Primary references
Editorial comments
Authors details and revision date

Changes to this new edition:
Contains revised and updated monographs
20 + new monographs including amino acids Arginine, Proline and Asparagine
Includes newly added Raman spectra for many excipients
New chapter content including information on excipients in oral solid dose formulations, and pediatric formulations

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Essentials of Pharmacy Law

 Pharmacology  Comments Off on Essentials of Pharmacy Law
Nov 212019
 

This book is a compilation and commentary of selected laws and regulations pertaining to the general practice of pharmacy in the United States. It is designed to be of assistance to practicing pharmacists, those seeking licensure by reciprocity, and other interested healthcare professionals.
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Space Pharmacology

 Pharmacology  Comments Off on Space Pharmacology
Nov 192019
 

“Space Pharmacology” is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each major physiological system in turn. Every section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussion looking forward to the new medical challenges we are likely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown.
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Antibacterial Drug Discovery to Combat MDR: Natural Compounds, Nanotechnology and Novel Synthetic Sources

 Pharmacology  Comments Off on Antibacterial Drug Discovery to Combat MDR: Natural Compounds, Nanotechnology and Novel Synthetic Sources
Nov 172019
 

This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
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Protein Allostery in Drug Discovery

 Pharmacology  Comments Off on Protein Allostery in Drug Discovery
Nov 172019
 

The book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes and controls physiological activities. Allostery can both cause human diseases and contribute to development of new therapeutics. Allosteric drugs exhibit unparalleled advantages compared to conventional orthosteric drugs, rendering the development of allosteric modulators as an appealing strategy to improve selectivity and pharmacodynamic properties in drug leads.
The Series delineates the immense significance of protein allostery—as demonstrated by recent advances in the repertoires of the concept, its mechanistic mechanisms, and networks, characteristics of allosteric proteins, modulators, and sites, development of computational and experimental methods to predict allosteric sites, small-molecule allosteric modulators of protein kinases and G-protein coupled receptors, engineering allostery, and the underlying role of allostery in precise medicine. Comprehensive understanding of protein allostery is expected to guide the rational design of allosteric drugs for the treatment of human diseases. The book would be useful for scientists and students in the field of protein science and Pharmacology etc.

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Pharmacogenomics of Alcohol and Drugs of Abuse

 Pharmacology  Comments Off on Pharmacogenomics of Alcohol and Drugs of Abuse
Nov 142019
 

Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy.
Applying
these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.

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Pharma-Nutrition: An Overview

 Nutrition, Pharmacology  Comments Off on Pharma-Nutrition: An Overview
Nov 042019
 

Natural products and functional/medical foods are now widely acknowledged as having an effect on the microbiome of the intestine, which in turn influences the outcome of certain disease.

This book reviews the impact and effects of natural products and functional/medical foods (nutritional programming) on disease management, specifically focusing on diseases related to 1) Inflammation and Immunity, 2) Cancer, COPD and Cachexia, 3) Allergy and 4) Brain Neuro/Immune. Hippocrates said “let medicine be thy food and food be thy medicine”. While most of us are familiar with Hippocrates famous words, we admit that in recent times, the disciplines of pharma and nutrition have evolved separately. Today, with the ever growing burden of diseases in modern society, we see a convergence of the two in relation to specific disease prevention and treatment. This re-discovered common ground between the complementary values of pharma and nutrition can be conceptualized in the term pharma-nutrition. Various chapters in the book review the aspects of molecular characteristics of food ingredients towards clinical effectiveness and relevance.

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