Tag Archives: Pathology

Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays.
These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.

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Hearing Aids for Speech-language Pathologists : A Guide to Modern Rehabilitative Audiology

Hearing aid technology changes at a rapid pace. For speech-language pathologists who work with individuals using hearing instruments, keeping up with the new technology can be challenging, and sometimes even intimidating. Hearing Aids for Speech-Language Pathologists is designed to remove the mystery and the confusing high-tech terms of the many hearing aid algorithms and features, by simply laying out the need-to-know aspects in an organized, easy to read and understand manner. The core of this text focuses on how modern hearing aids work, and the tests associated with the fitting of these instruments. Attention is given to both the school age and adult hearing aid user. Recent developments such as situation detection, rechargeability and wireless connectivity are reviewed in detail, as well as the popular use of smartphone apps to allow the user to control the processing. Amplification is not just hearing aids, and therefore chapters also have been dedicated to implantable amplification strategies, FM and Bluetooth solutions. Hearing aid fitting cannot be studied in isolation, but rather, how it fits into the complete treatment of the patient with hearing loss, including the audiologic rehabilitative process. For this reason, the beginning chapters of the book are devoted to a review of the basics of the modern audiologic evaluation and the associated auditory pathologies. Readers will also find portions of the book that address hearing screening in the schools, rehabilitative techniques and auditory training. Practicing speech-language pathologist and graduate students will find that this text provides the latest in concise and practical information in the areas of hearing aids and rehabilitative audiology. Hearing Aids for Speech-Language Pathologists is authored by two of the industry’s leading authorities on adult amplification, who have carefully crafted a text that provides speech-language pathologists with the essential information to work comfortably with hearing instruments and their accessories for individuals of all ages.

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Netter’s Essential Histology: With Correlated Histopathology (Netter Basic Science) – 3rd Edition (April 2020 Release)

With strong correlations between gross anatomy and the microanatomy of structures, Netter’s Essential Histology, 3rd Edition, is the perfect text for today’s evolving medical education. Concise and easy to use, it integrates gross anatomy and embryology with classic histology slides and state-of-the-art scanning electron microscopy, offering a clear, visual understanding of this complex subject. Additional histopathology images, more clinical boxes, and new histopathology content ensure that this textbook-atlas clearly presents the most indispensable histologic concepts and their clinical relevance.

  • Helps you recognize both normal and diseased structures at the microscopic level with the aid of succinct explanatory text as well as numerous clinical boxes.
  • Features more histopathology content and additional clinical boxes to increase your knowledge of pathophysiology and clinical relevance.
  • Includes high-quality light and electron micrographs, including enhanced and colorized electron micrographs that show ultra-structures in 3D, side by side with classic Netter illustrations that link your knowledge of anatomy and cell biology to what is seen in the micrographs.
  • Provides online access to author-narrated video overviews of each chapter, plus Zoomify images and Virtual Slides that include histopathology and can be viewed at different magnifications.

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The Molecular Pathology of Autoimmune Diseases

Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.

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Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepatitis, arthritis, celiac disease, myeloproliferative disorders, neurology, and wound healing. The authors write from years of experience in diagnostic practice and pharmaceutical drug development, aiming to educate pharmaceutical and academic scientists how to best use tissue to diagnose disease and improve the process of drug development.  As part of the Methods in Pharmacology and Toxicology series, this volume is designed to provide wisdom and examples that others can follow and apply as part of drug development.
Comprehensive and practical, Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development will inform and enlighten both tissue-focused and non-tissue-focused drug development professionals about better use and interpretation of the multidimensional data contained in a tissue biopsy.

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Porth’s Pathophysiology: Concepts of Altered Health States

Succeed in your pathophysiology text with this 9th edition of Porth’s Pathophysiology: Concepts of Altered Health States. Captivating and easy-to understand, this proven book provides comprehensive, nursing-focused coverage designed to help you grasp both the physical and psychological aspects of altered health.
Master the most clinically relevant and difficult to understand disorderswith advanced 3D narrated animations.
Prepare for clinical practice with 14 unit-opening case studies that put a real face on pathophysiology and help you relate the clinical presentation to the underlying pathophysiology.
Master the information you need for success in your career with the unparalleled coverage of disease processes that make this text the most comprehensive pathophysiology text available.
Increase your understanding of key concepts with the full-color art program that illustrates the clinical manifestations of diseases and disease processes.
Find the information you need fast with the book’s consistent presentation of each disease , with detailed coverage of pathophysiology, clinical manifestations, and evaluation and treatment.
Reinforce your understanding of key content with chapter-ending review exercises .
Develop a strong understanding of pathophysiology concepts with the easy-to-follow narrative that builds concepts on one another, defines words as content is presented, and reviews concepts from physiology, biochemistry, physics, and other sciences along the way.
Deepen your understanding by pausing and reviewing salient points using the easily-identified section-opening Objectives and section-ending Summaries.
Retain and apply text information using Key Concepts Boxes help you incorporate key information into a larger conceptual unit, rather than memorizing a string of related and unrelated facts.
Easily access useful references including lists of common suffixes and prefixes, normal laboratory values in both conventional and SI units, and a comprehensive glossary.
Take your understanding beyond the book with anytime, anywhere access to the fully searchable eBook online.

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Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies

Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily “scope-side guide,” it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
More than 1,600 high-quality photomicrographs capture the subtle morphologic spectrum of neoplastic processes of the tubular GI tract. Each image is captioned with key diagnostic considerations and includes call-outs showing subtle features and diagnostic clues.
Practical tools throughout the text include:
Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options o Discussions of how and when to incorporate molecular tools o Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports
Relevant endoscopic images, photographs of select gross specimens, and medical figures
Brief reviews of normal histology that provide contrast to succeeding patterns
“Pearls and Pitfalls” and “Near Misses” sections with lessons from real life sign-out experience
“Frequently Asked Questions” sections that discuss common diagnostic dilemmas
“Sample Note” sections that offer a template of how to synthesize complicated or especially challenging topics
Quizzes in every chapter that provide experience with high-yield, board-style teaching topics
Enhance Your eBook Reading Experience
Read directly on your preferred device(s), such as computer, tablet, or smartphone.
Easily convert to audiobook, powering your content with natural language text-to-speech.

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The Neuropathology of Dementia

Completely rewritten and updated, this new edition is almost twice the size of its predecessor. It presents practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes three chapters on neuroimaging, molecular diagnostics, and transgenic models; two chapters on tauopathies under new authorship and a chapter under new authorship on synucleinopathies, including multiple system atrophy.

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Gynecologic and Urologic Pathology: Similarities, Differences and Challenges

Due to common early development, the pathology of the urogenital tract in males and females present many similarities. Richly illustrated in colour throughout, this essential text evaluates the most common pathologies of the male and female urogenital tract, focussing on similarities, differences, and challenges. Images are colour coded by gender, and feature diagnostic algorithms and boxes highlighting key similarities and differences. This book is intended to bridge the gap between urologic and gynecologic specialties, whose diagnoses are rarely considered or studied together. Understanding common development, similarities and differences is extremely valuable for the evaluation of pathologic features and related dysfunctions. This comprehensive resource will be invaluable to urological and gynaecological pathologists,residents, general pathologists, and for consultants in urology and gynaecology to gain experience in the pathologic diagnostic rationale. This book provides entry to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.

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Pathophysiology: Step By Step Guide for Nursing & NP Students

Get familiar with the basic ideas of pathophysiology and keep updated on the latest scientific findings, drugs, and diseases.
Our guide is full of specific and detailed information that will be key to passing your exam. Concepts and principles aren’t simply named or described in passing but explain in detail.
If you are as yet picking up Nursing, Pathophysiology will assist you with acing complex subjects in minutes with unique components found all through the content to make it straightforward and recollect key focuses and data
Inside this guide, you will learn:
• Pathophysiology basics – cellular structure; how cells reproduce, age, and die; adaptive cell changes; the concept of homeostasis and how it affects the body; the causes of disease; and the disease development process
• Infection, cancer, and genetics – the body’s defense mechanisms against infection, types of infective microorganisms and how they invade the body, common infectious disease pathophysiology, classifications of cancer, warning signs of cancer, the cancer metastasis process, the role of genes and chromosomes, how cells divide, and genetic abnormalities
• Cancer as it affects individual body systems – cardiovascular, respiratory, neurologic, gastrointestinal, endocrine, renal system, hematologic, immune, integumentary, sensory, and reproductive system.
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