Medical Otology and Neurotology

 Neurology/Neurosurgery  Comments Off on Medical Otology and Neurotology
Jan 132022
 

This timely book reflects trends in managing patients with inner ear
disease through medical means rather than through surgical treatment. Covering
the clinical applications of cutting-edge research, including regenerative
medicine for inner ear disease, inner ear perfusion treatments, vestibular
rehabilitation for balance retraining, and the use of cochlear implants, this
text keeps you abreast of the latest advances and information in the field. You
will learn how to diagnose and manage peripheral auditory and vestibular

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Neuro-Ophthalmology (What Do I Do Now) 2nd Edition

 Neurology/Neurosurgery, Ophthalmology  Comments Off on Neuro-Ophthalmology (What Do I Do Now) 2nd Edition
Jan 122022
 

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Pediatric Neuroimaging 6th Edition

 Neurology/Neurosurgery, Pediatrics, Radiology  Comments Off on Pediatric Neuroimaging 6th Edition
Jan 082022
 

This newest addition of the comprehensive Pediatric Neuroimaging combines thousands of images with detailed textual descriptions to help you diagnose a wide range of brain, spinal, and head and neck disorders in the pediatric patient. The authors have chosen a clear, concise writing style that encourages you to grasp information quickly. By dealing with a broad range of disorders, from everyday problems to less common ones, and explaining how to recognize and differentiate them, this book offers you the opportunity to provide a concise differential diagnosis on most patients you are likely to encounter in your practice.
Packed with more than 2,500 high-quality illustrations, drawings, photographs, and figures.
Emphasizes CT and MRI imagery—widely regarded as the optimal modalities for assessing and diagnosing children.
Most chapters organized by disease group, and describe the pathologic bases of each disorder to illustrate important clinical contexts.
Broadly discusses common imaging techniques in children, as well as images of normal childhood development in the brain, skull, and spine.
Prominently displayed lists of disorders help quickly identify a disorder within the text.

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Adapt for unique reading needs , supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more

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On Call Neurology: On Call Series 4th Edition

 Neurology/Neurosurgery  Comments Off on On Call Neurology: On Call Series 4th Edition
Jan 052022
 

Ideal for any on-call professional, resident, or medical student, this popular reference covers the common problems you’ll encounter while on call in the hospital. On Call Neurology, 4th Edition, by Drs. Randolph S. Marshall and Stephan A. Mayer, fits perfectly in your pocket, ready to provide key information in time-sensitive, challenging situations. You’ll gain speed, skill, and knowledge with every call – from diagnosing a difficult or life-threatening situation to prescribing the right medication.

    • Features a logical, highly templated format so you can locate key information quickly
    • Provides updated content and references, keeping you on the cutting edge of current, evidence-based information.
    • Includes the latest information on headache, demyelinating diseases, infections of the central nervous system, dementia, and more.
    • Highlights critical information, reducing the likelihood of error.
    • Provides an updated On Call Formulary covering the most common neurologic medications.
    • Delivers consistent, easy-to-follow coverage of the most common on-call problems and approaches, including what to do from the initial phone call, questions you should ask to assess the urgency of each situation, “Elevator Thoughts,” how to immediately identify major threats to life, what to do at the bedside, and how to avoid common mistakes for every call.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
    • Provides updated content and references, as well as an up-to-date drug formulary, keeping you on the cutting edge of current, evidence-based information.
    • Includes the latest information on headache, demyelinating diseases, infections of the central nervous system, dementia, and more.
  • NEW! Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

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Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

 Neurology/Neurosurgery  Comments Off on Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases
Jan 042022
 

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

    • Provides in-depth knowledge about neurotoxic potential of transition metals, impaired mitochondrial dynamics in the brain neurons, mutant proteins Aß peptide, tau protein, a-synuclein, huntingtin protein and formation of Lewy bodies, reactive oxygen and nitrogen species, ubiquitin proteasome dysregulation, and many others in neurodegenerative diseases

 

    • Elucidates neurogenetics of gene APP, gene PSEN1, gene APOE, gene LRRK2, gene DJ1, and others in the pathology of neurodegenerative diseases.

 

  • Explains caspases-mediated neuronal apoptosis in pathogenesis of Alzheimer’s disease covering amyloidogenesis, caspase-activated DNase, rho-associated coiled coil–containing protein kinase 1, mammalian sterile 20-like kinase 1, role of synaptic loss, microglial TREM2 receptor, microglial LRP1 receptor, microglial advanced glycation end-product receptor, astrocytic glial a 7 subtypes of nAChR, NLRP3 inflammasome, P2X purinoreceptors, miRNAs, and many other factors

 

    • Demonstrates the role of caspases and apoptosis in Parkinson’s disease covering truncation of a-synuclein, neuroinflammation, parkin protein, activation of microglial cells, extrinsic and intrinsic pathways of apoptosis, ?tau314, and several other factors

 

  • Explains etiopathogenesis of Huntington’s disease through covering clinically important topics as role of exon 1 HTT protein, ubiquitous nature of huntingtin, length of expanded polyglutamine tract, classically and alternately activated microglia, nuclear factor kappa B, kynurenine signaling pathway, tumor suppressor protein, PGC-1a gene, advanced glycation end-products, autophagy, and many other significant topics.

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Neuroproteomics

 Neurology/Neurosurgery  Comments Off on Neuroproteomics
Jan 042022
 

The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Similarly, the review on the role of neuroproteomics in elucidating mechanisms of drug addiction provides an overview of the utility of MS/proteomics approaches for addressing critical questions in addiction neuroscience that should be applicable to investigators involved in virtually any area of biomedical research. Likewise, the article on developing targeted MS approaches for quantifying postsynaptic density proteins will be useful for any investigator who wishes to design targeted assays for virtually any protein. Finally, the peroxidase-mediated proximity labeling technology, described in the article on mapping the proteome of the synaptic cleft, will be of interest to investigators interested in mapping other spatially restricted proteomes.

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Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications 5th Edition

 Neurology/Neurosurgery, Pharmacology, Psychiatry  Comments Off on Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications 5th Edition
Jan 042022
 

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Diagnosis of Neurogenetic Disorders: Contribution of Next Generation Sequencing and Deep Phenotyping

 Neurology/Neurosurgery  Comments Off on Diagnosis of Neurogenetic Disorders: Contribution of Next Generation Sequencing and Deep Phenotyping
Jan 012022
 

The contribution of genomic variants to the aetiopathogenesis of both paediatric and adult neurological disease is being increasingly recognized. The use of next-generation sequencing has led to the discovery of novel neurodevelopmental disorders, as exemplified by the deciphering developmental disorders (DDD) study, and provided insight into the aetiopathogenesis of common adult neurological diseases. Despite these advances, many challenges remain. Correctly classifying the pathogenicity of genomic variants from amongst the large number of variants identified by next-generation sequencing is recognized as perhaps the major challenge facing the field. Deep phenotyping (e.g., imaging, movement analysis) techniques can aid variant interpretation by correctly classifying individuals as affected or unaffected for segregation studies. The lack of information on the clinical phenotype of novel genetic subtypes of neurological disease creates limitations for genetic counselling. Both deep phenotyping and qualitative studies can capture the clinical and patient’s perspective on a disease and provide valuable information. This Special Issue aims to highlight how next-generation sequencing techniques have revolutionised our understanding of the aetiology of brain disease and describe the contribution of deep phenotyping studies to a variant interpretation and understanding of natural history.

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Neurological Practice: An Indian Perspective – E-Book

 Neurology/Neurosurgery  Comments Off on Neurological Practice: An Indian Perspective – E-Book
Dec 302021
 

    • Thoroughly revised and updated text and references

 

  • Each chapter deals with the Indian perspective of epidemiology, clinical presentations and

prevalent management principles, pointing out the differences and similarities with world literature

 

  • More diagrams, figures and tables are added to make the text self-explanatory
    • Headache

 

  • Tumours of Central Nervous System

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Adult Epilepsy, 2nd Edition

 Neurology/Neurosurgery  Comments Off on Adult Epilepsy, 2nd Edition
Dec 302021
 

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