Review of Medical Microbiology and Immunology, 15th Edition

 Immunology, Microbiology  Comments Off on Review of Medical Microbiology and Immunology, 15th Edition
May 082020
 

The most concise, clinically relevant, and current review of medical microbiology and immunology

Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology and also discusses important infectious diseases using an organ system approach. The book emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, Q&A, and clinical vignettes.

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Regulation of Cancer Immune Checkpoints: Molecular and Cellular Mechanisms and Therapy (Advances in Experimental Medicine

 Immunology, Oncology  Comments Off on Regulation of Cancer Immune Checkpoints: Molecular and Cellular Mechanisms and Therapy (Advances in Experimental Medicine
Apr 252020
 

This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic. The past decade has seen major advances in cancer immune checkpoint therapy, which has demonstrated impressive clinical benefits. The family of checkpoints for mediating cancer immune evasion now includes CTLA-4, PD-1/PD-L1, CD27/CD70, FGL-1/LAG-3, Siglec-15, VISTA (PD-1L)/VSIG3, CD47/SIRPA, APOE/LILRB4, TIGIT, and many others. Despite these strides, most patients do not show lasting remission, and some cancers have been completely resistant to the therapy. The potentially lethal adverse effects of checkpoint blockade represent another major challenge, the mechanisms of which remain poorly understood. Compared to the cancer signaling pathways, such as p53 and Ras, mechanistic studies on immune checkpoint pathways are still in their infancy.
To improve the responses to checkpoint blockade therapy and limit the adverse effects, it is essential to understand the molecular regulation of checkpoint molecules in both malignant and healthy cells/tissues. This book begins with an introduction to immune checkpoint therapy and its challenges, and subsequently describes the regulation of checkpoints at different levels. In closing, it discusses recent therapeutic developments based on mechanistic findings, and outlines goals for future translational studies. The book offers a valuable resource for researchers in the cancer immunotherapy field, helping to form a roadmap for checkpoint regulation and develop safer and more effective immunotherapies.

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Tumor Immunology and Cancer Vaccines

 Immunology, Oncology  Comments Off on Tumor Immunology and Cancer Vaccines
Apr 212020
 

– Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians
– Text includes clinical trials
– Written by leaders in the field

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Veterinary Immunology: Principles and Practice, Second Edition Edition 2

 Immunology  Comments Off on Veterinary Immunology: Principles and Practice, Second Edition Edition 2
Apr 162020
 

Veterinary Immunology: Principles and Practice has become the adopted text in numerous veterinary schools throughout the world. Widely updated with advances in knowledge since 2011, this second edition reflects the rapid development in the field.
The new edition presents expanded information on commonly used diagnostic test procedures and discusses newly arising diseases such as bovine neonatal pancytopenia. Maintaining the same reliable format as its predecessor, the book includes:
Learning objectives at the start of each chapter
Key points at the end of each chapter
17 clinical case studies demonstrating clinical context for the material covered in the chapters
Standard symbols in diagrams throughout the text to provide continuity
Clinical examples and clinicopathological figures throughout
A glossary of terms and list of commonly used abbreviations
Exploring the immunological concerns of both large animals and small, the book emphasizes immunological principles while applying them to the disease process and to clinical practice. It provides a practical textbook for veterinary students and a handy reference for practitioners.

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Dynamics of Immune Activation in Viral Diseases

 Immunology  Comments Off on Dynamics of Immune Activation in Viral Diseases
Mar 302020
 

This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammation, cytokines such as interferon, toll-like receptors and leukocytes in the initial detection of invading viruses and subsequent activation of adaptive immunity.
It also summarizes the role of the adaptive immunity against viral infections through clearance of virus and establishment of memory response that protects against the recurrent infections. In addition, the book examines the role of DNA and RNA sensors in viral recognition and in controlling viral infection.
Lastly, it reviews the latest developments in the development of the rational viral vaccines. As such it is a useful resource book for postgraduate and early researchers wanting to gain insights into the immune response to viral infections.
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Immunology of Fungal Infections

 Immunology, Infectious Diseases  Comments Off on Immunology of Fungal Infections
Mar 262020
 

This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.
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From Innate Immunity to Immunological Memory

 Immunology  Comments Off on From Innate Immunity to Immunological Memory
Mar 262020
 

The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This book assembles a collection of essays from leading experts that span the entire spectrum of immunological research, from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.
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Autoimmune Diseases: Acute and Complex Situations

 Immunology  Comments Off on Autoimmune Diseases: Acute and Complex Situations
Mar 262020
 

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions.

Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential.

Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

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Immunogenicity of Biopharmaceuticals

 Immunology, Pharmacology  Comments Off on Immunogenicity of Biopharmaceuticals
Mar 072020
 

Immunogenicity of Biopharmaceuticals is the first book to comprehensively address the potential of an immune response to biopharmaceuticals. It is intended to give a broad overview of the current state-of-the-art regarding this subject. The chapters range from an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity.

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Autoimmune Liver Disease: Management and Clinical Practice

 Gastroenterology/Hepatology, Immunology  Comments Off on Autoimmune Liver Disease: Management and Clinical Practice
Feb 292020
 

A practical guide to autoimmune liver diseases through pathogenesis, diagnosis, and management
In Autoimmune Liver Disease Management and Clinical Practice, practitioners will learn about the current state of autoimmune liver disease and how to focus on their diagnosis and treatment. The four-part book begins with a thorough investigation of current immunological thinking as it relates to the autoimmunity of the liver. It also covers the four major hepatic autoimmune liver diseases in both adults and children, their management and the role of liver transplantation, and learned approaches to patient management and empowerment.
Expert authors in the field have come together to provide a thorough examination of autoimmune liver disease to help support clinicians assisting patients. The text provides an in-depth look at topics including:
● The four major hepatic autoimmune liver diseases, their diagnosis, and potential disease management
● The use (and misuse) of autoantibodies in diagnosis and treatment
● The role and timing of liver transplantation and the impact of recurrent autoimmune liver disease as well as de novo autoimmune hepatitis
● Optimal approaches to managing patients and keeping care personalised
With breadth, depth and current-day relevance, Autoimmune Liver Disease sheds light on recent developments in management of liver disease for practitioners, nurses, and health care professionals.

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