Dec 112015
 

Gene Therapy for Neurological Disorders: Methods and Protocols (Methods in Molecular Biology)


This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

List Price: $179.00 USD
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Dec 082015
 

Genetic Privacy: An Evaluation of the Ethical and Legal Landscape


By (author): Terry Sheung-Hung Kaan, Calvin Wai-Loon Ho

Privacy is an unwieldy concept that has eluded an essentialised definition despite its centrality and importance in the body of bioethics. The compilation presented in this volume represents continuing discussions on the theme of privacy in the context of genetic information. It is intended to present a wide range of expert opinion in which the notion of privacy is examined from many perspectives, in different contexts and imperatives, and in different societies, with the hope of advancing an understanding of privacy through the examination and critique of some of its evolving component concepts such as notions of what constitute the personal, the context of privacy, the significance and impact of the relational interests of others who may share the same genetic inheritance, and mechanisms for the protection of privacy (as well as of their limitations), among others. More specifically, the discussions in this volume encourages us to think broadly about privacy, as encompassing values that are entailed in the sociality of context and of relations, and also as freedom from illegitimate and excessive surveillance. A long-standing question that continues to challenge us is whether genetic information should be regarded as exceptional, as it is often perceived. A conclusion that could be derived from this volume is that while genetic information may be significant, it is not exceptionally so. The work presented in this volume underlines the continuing and growing relevance of notions of privacy to genomic science, and the need to take ownership of a genetic privacy for the future through broad, rigorous and open discussion.

Contributors: Alastair V Campbell, Benjamin Capps, Jacqueline JL Chin, Oi Lian Kon, Kenji Matsui, Thomas H Murray, Nazirudin Mohd Nasir, Dianne Nicol, Anh Tuan Nuyen, Onora O’Neill, Margaret Otlowski, Yvette van der Eijk, Chunshui Wang, Ross S White.

Readership: Students and professionals in medical law and medical ethics, public policy, Asian studies and public health.

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Jul 152015
 

Epigenetics and Pathology: Exploring Connections Between Genetic Mechanisms and Disease Expression


This title includes a number of Open Access chapters.

This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:

  • host-pathogen interactions
  • causal relationships between genes and the environment
  • the effects of environmental chemicals on gene expression
  • DNA methylation

The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.

This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.

List Price: $169.95 USD
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Jul 152015
 

Movement Disorder Genetics


This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided into three sections: technical and scientific aspects; clinical aspects with guidance towards work-up; and ethical and legal aspects of genetic testing in a clinical and research setting.

The first section includes chapters on genetic analysis and counselling with critical discussion of potential problems when interpreting the results. Clinical chapters summarize genetic forms of movement disorders including parkinsonism, tics and dystonia with algorithms for hands-on daily practice. Related conditions such as RLS, ataxias and dementias are also covered. Finally, chapters on ethical and legal aspects of genetic testing are included.

Movement Disorder Genetics is aimed at clinicians and scientists working in the field of movement disorders and related conditions.  

List Price: $179.00 USD
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Mar 122015
 

USMLE Road Map: Genetics (LANGE USMLE Road Maps)


By (author): Jr., George Sack

THE EXPRESS ROUTE TO USMLE EXCELLENCE IN GENETICS

High-Yield * Illustrated * USMLE Shortcuts

You’ll never find an easier, more efficient, and more focused way to ace genetics and genetics-related questions on the USMLE and course examinations than the USMLE Road Map. Designed to provide maximum learning in minimum time, this fully updated USMLE Road Map offers a concise, creative, and well-illustrated approach to mastering genetics.

The right way–the right questions–the right results

  • USMLE Shortcuts for effective USMLE preparation
  • Outline Format guides you through the most important areas in genetics
  • High-Yield Facts promote comprehension and recall
  • Two-Color Format and Illustrations make essential concepts easy to understand and remember
  • Learning Tips and Tricks garnered from years of interaction with students just like you
  • Clear Explanations from instructors with the experience to know the questions you would ask
List Price: $40.00 USD
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Oct 042014
 

Genetics for Pediatricians: The Molecular Genetic Basis of Pediatric Disorders


Features: Used Book in Good Condition
By (author): Mohnish Suri, Ian Young

Genetic testing now plays an important role in the investigation of almost every child who presents with one of the many commonly inherited disorders that make a major contribution to pediatric morbidity and mortality throughout the world. It can be difficult for even the most conscientious practitioner to keep abreast of developments and to appreciate both the significance and relevance of some of the major discoveries of recent years. The number of conditions that have been mapped or in which the causative gene has been isolated is vast. In this book, coverage has been restricted to the more common single-gene disorders that are likely to be encountered in general pediatric practice, with particular attention focused on those in which molecular analysis can play an important role in the diagnosis or management of a child and his or her family.
List Price: $30.00
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Jun 022014
 

BRS Biochemistry, Molecular Biology, and Genetics (Board Review Series)


Features: Used Book in Good Condition
By (author): Michael Lieberman PhD, Rick Ricer MD

BRS Biochemistry, Molecular Biology, and Genetics is an excellent aid for USMLE Step 1 preparation and for coursework in biochemistry, molecular biology, and genetics. Fully updated for its sixth edition, chapters are written in an outline format and include pedagogical features such as bolded key words, figures, tables, algorithms, and highlighted clinical correlates. USMLE-style questions and answers follow each chapter and a comprehensive exam appears at the end of the book.
List Price: $51.99 USD
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Mar 302014
 

Emery’s Elements of Medical Genetics: With STUDENT CONSULT Online Access, 14e (Turnpenny, Emery’s Elements of Medical Genetics)


By (author): Peter D Turnpenny BSc MB ChB FRCP FRCPCH, Sian Ellard BSc PhD MRCPath

Master the genetics you need to know with the updated 14th Edition of Emery’s Elements of Medical Genetics by Drs. Peter Turnpenny and Sian Ellard. Review the field’s latest and most important topics with user-friendly coverage designed to help you better understand and apply the basic principles of genetics to clinical situations. Learning is easy with the aid of clear, full-color illustrative diagrams, a wealth of clinical photographs of genetic diseases, multiple-choice and case-based review questions, end-of-chapter summaries, and convenient online access at www.studentconsult.com. With this highly visual, award-winning classic in your hands, you have all the genetics knowledge you need for exams or practice.

  • Get a broad view of medical genetics with a unique three-part structure that looks at the Principles of Human Genetics, Genetics in Medicine, and Clinical Genetics.
  • Visualize the appearance of genetic disorders with a fantastic art program that presents many clinical photos of genetic diseases, and work through complicated ideas with an array of full-color illustrative diagrams.
  • Master the material you need to know with a title preferred by faculty and students alike over the last three decades and awarded the British Medical Association Medial Student Textbook of the Year in 2008.

Search the entire contents online at www.studentconsult.com, including 150 USMLE-style multiple choice questions to aid study and self-testing.

  • Apply the latest research with chapters on developmental genetics, cancer genetics, prenatal testing and reproduction genetics, ‘clonal’ sequencing, and more.
  • Understand complex concepts with the help of an increased number of diagrams.
  • Be fully aware of social, ethical, and counseling issues by reviewing an improved section on these topics.
List Price: $69.95 USD
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Nov 102013
 

Emery and Rimoin’s Essential Medical Genetics


Features: Used Book in Good Condition

For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. Developed in parallel to the sixth edition, and featuring 174 original contributions from the many authors of the full set, this one volume work expertly condenses and synthesizes the most clinically relevant content, for convenient desk reference.

Helping to bridge the gap between high-level molecular genetics and individual application, it follows the multi-volume set in encompassing scientific fundamentals, full spectrum discussion of major inherited disorders, and actionable therapies. Clinically oriented information is supported by concise descriptions of the principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease.

This print volume is complemented and enhanced with online access to the complete text, online-only references, and high quality illustrations on www.expertconsult.com.

  • Features 174 summarized contributions concisely discussing advances in cancer genetics, genomic technologies, and molecular genetics
  • Contains hundreds of full colour illustrations supporting users with identification, concept illustration, and method processing
  • Enhanced with full text online access, high quality illustrations, and online-only references at www.expertconsult.com
List Price: $249.95 USD
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