Mar 262017
 

Application of Infrared to Biomedical Sciences (Series in BioEngineering)


The book covers the latest updates in the application of infrared to biomedical sciences, a non-invasive, contactless, safe and easy approach imaging of skin and tissue temperatures. Its diagnostic procedure allows practitioners to identify the locations of abnormal chemical and blood vessel activity such as angiogenesis in body tissue. 

Its non-invasive approach works by applying the technology of the infrared camera and state-of-the-art software, where high-resolution digital infrared imaging technology benefits highly from enhanced image production, standardized image interpretation protocols, computerized comparison and storage, and sophisticated image enhancement and analysis. 

The book contains contributions from global prominent scientists in the area of infrared applications in biomedical studies. The target audience includes academics, practitioners, clinicians and students working in the area of infrared imaging in biomedicine.

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Mar 262017
 

Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery


This text provides a comprehensive, state-of-the art definitive “case-based” reference for the work-up, diagnosis, intraoperative management, and peri-operative care of patients with complex, difficult to manage HPB diseases. The book provides a practical, clinically useful guide that reviews select complicated HPB cases, as well as providing key information on how to manage such patients. This text provides detailed “case-based” algorithms, as well as specific guidance on the management of complicated HPB patients. In addition, it also focuses on key points on how to work-up patients pre-operatively, highlights intra-operative technical “pearls”, and defines optimal post-operative care. Chapters are rich with images, have multiple “call out” boxes to highlight key lessons learned and also include clinical management “pearls.”  All chapters are written by experts in their field and include the most up-to-date clinical information from national and world leaders in their respective discipline.
Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery will serve as a very useful resource for physicians, fellows and residents dealing with complex HPB patients. In addition, It will provide a concise yet comprehensive summary of the diagnosis, work-up, and management of some of the most complex, yet common, HPB cases.
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Mar 262017
 

The Health of Newcomers: Immigration, Health Policy, and the Case for Global Solidarity


By (author): Patricia Illingworth, Wendy E. Parmet

Immigration and health care are hotly debated and contentious issues. Policies that relate to both issues—to the health of newcomers—often reflect misimpressions about immigrants, and their impact on health care systems. Despite the fact that immigrants are typically younger and healthier than natives, and that many immigrants play a vital role as care-givers in their new lands, native citizens are often reluctant to extend basic health care to immigrants, choosing instead to let them suffer, to let them die prematurely, or to expedite their return to their home lands. Likewise, many nations turn against immigrants when epidemics such as Ebola strike, under the false belief that native populations can be kept well only if immigrants are kept out. 

In The Health of Newcomers, Patricia Illingworth and Wendy E. Parmet demonstrate how shortsighted and dangerous it is to craft health policy on the basis of ethnocentrism and xenophobia. Because health is a global public good and people benefit from the health of neighbor and stranger alike, it is in everyone’s interest to ensure the health of all. Drawing on rigorous legal and ethical arguments and empirical studies, as well as deeply personal stories of immigrant struggles, Illingworth and Parmet make the compelling case that global phenomena such as poverty, the medical brain drain, organ tourism, and climate change ought to inform the health policy we craft for newcomers and natives alike. 

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Mar 262017
 

Clinical Trials in Ovarian Cancer


By (author): Christine S. Walsh M.D.

When a patient is diagnosed with a gynecological malignancy, she and her doctors must make urgent, high-risk decisions about her course of treatment. In selecting an appropriate plan of care, physicians must weigh the patient’s individual needs, the tumor’s specific characteristics, and the treatment’s potential side effects. Because there is no one-size-fits-all treatment solution, a plethora of clinical trials have been performed on ovarian cancer patients, but clinicians may struggle to keep up with this ever-growing body of research.   
 
Collecting and synthesizing research findings from a wide array of medical journal articles and book chapters, Clinical Trials in Ovarian Cancer provides physicians with an invaluable resource. Gynecologic oncologist Christine S. Walsh systematically outlines each of the seminal Phase III trials that have shaped the treatment of ovarian cancers, detailing the rationale for the trial, the patient population studied, treatment delivery methods, efficacy, toxicity, and trial conclusions. She provides a clear overview of established treatments, as well as still-controversial experimental approaches. 
 
The first book to organize this cutting-edge research into an easy-to-use reference, Clinical Trials in Ovarian Cancer should help medical personnel at all levels provide their patients with the highest standard of care. 
 
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Mar 262017
 

Health Economics from Theory to Practice: Optimally Informing Joint Decisions of Research, Reimbursement and Regulation with Health System Budget Constraints and Community Objectives


By (author): Simon Eckermann

This book provides a robust set of health economic principles and methods to inform societal decisions in relation to research, reimbursement and regulation (pricing and monitoring of performance in practice). We provide a theoretical and practical framework that navigates to avoid common biases and suboptimal outcomes observed in recent and current practice of health economic analysis, as opposed to claiming to be comprehensive in covering all methods. Our aim is to facilitate efficient health system decision making processes in research, reimbursement and regulation, which promote constrained optimisation of community outcomes from a societal perspective given resource constraints, available technology and processes of technology assessment. Importantly, this includes identifying an efficient process to maximize the potential that arises from research and pricing in relation to existing technology under uncertainty, given current evidence and associated opportunity costs of investment. Principles and methods are identified and illustrated across health promotion, prevention and palliative care settings as well as treatment settings. Health policy implications are also highlighted.

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Mar 262017
 

Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management (Current Clinical Neurology)


This thoroughly updated edition covers all clinical aspects of neuroinflammation.  The latest developments in pathogenesis  and advances in treatment are provided, along with an understanding of the immune system’s role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade.  Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.

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Mar 262017
 

Mercies in Disguise: A Story of Hope, a Family’s Genetic Destiny, and the Science That Rescued Them


By (author): Gina Kolata

New York Times science reporter Gina Kolata follows a family through genetic illness and one courageous daughter who decides her fate shall no longer be decided by a genetic flaw.

The phone rings. The doctor from California is on the line. “Are you ready Amanda?” The two people Amanda Baxley loves the most had begged her not to be tested?at least, not now. But she had to find out.

If your family carried a mutated gene that foretold a brutal illness and you were offered the chance to find out if you’d inherited it, would you do it? Would you walk toward the problem, bravely accepting whatever answer came your way? Or would you avoid the potential bad news as long as possible?

In Mercies in Disguise, acclaimed New York Times science reporter and bestselling author Gina Kolata tells the story of the Baxleys, an almost archetypal family in a small town in South Carolina. A proud and determined clan, many of them doctors, they are struck one by one with an inscrutable illness. They finally discover the cause of the disease after a remarkable sequence of events that many saw as providential. Meanwhile, science, progressing for a half a century along a parallel track, had handed the Baxleys a resolution?not a cure, but a blood test that would reveal who had the gene for the disease and who did not. And science would offer another dilemma?fertility specialists had created a way to spare the children through an expensive process.

A work of narrative nonfiction, Mercies in Disguise is the story of a family that took matters into its own hands when the medical world abandoned them. It’s a story of a family that had to deal with unspeakable tragedy and yet did not allow it to tear them apart. And it is the story of a young woman?Amanda Baxley?who faced the future head on, determined to find a way to disrupt her family’s destiny.

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Release date March 21, 2017.

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Mar 262017
 

IgG4-Related Disease (Current Topics in Microbiology and Immunology)


This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike.

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Mar 262017
 

Oncologic Imaging: Spine and Spinal Cord Tumors


By (author): Heung Sik Kang, Joon Woo Lee, Eugene Lee

This book is a detailed guide to image interpretation in patients with spine and spinal cord tumors that will enable clinicians and residents to improve their diagnostic abilities. The book opens by introducing basic concepts in the imaging of spinal tumors, namely the compartmental approach and the histologic basis for the different imaging appearances. These concepts are explained with the aid of representative cases and schematic illustrations. The second part of the book represents a “training step” in which various spinal tumors are described in detail, focusing on the imaging findings. Representative cases are presented with radiographic, CT, and MR images; in addition, schematic illustrations and pathologic or operative images are included in selected cases. The third part is a “practice step” describing tips for correct imaging diagnosis. Individual chapters in this part focus on incidence-, age-, location-, and imaging pattern-based approaches to bone, extradural, intradural extramedullary, intramedullary, and pediatric spinal tumors. The presented cases will enhance the reader’s understanding of the different tumor patterns and assist in solving diagnostic problems that may be encountered in daily practice.
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Mar 262017
 

Physiological Aspects of Legged Terrestrial Locomotion: The Motor and the Machine


By (author): Giovanni Cavagna

This book offers a succinct but comprehensive description of the mechanics of muscle contraction and legged terrestrial locomotion. It describes on the one hand how the fundamental properties of muscle tissue affect the mechanics of locomotion, and on the other, how the mechanics of locomotion modify the mechanism of muscle operation under different conditions.

Further, the book reports on the design and results of experiments conducted with two goals. The first was to describe the physiological function of muscle tissue (which may be considered as the “motor”) contracting at a constant length, during shortening, during lengthening, and under a condition that occurs most frequently in the back-and-forth movement of the limbs during locomotion, namely the stretch-shortening cycle of the active muscle. The second objective was to analyze the interaction between the motor and the “machine” (the skeletal lever system) during walking and running in different scenarios with respect to speed, step frequency, body mass, gravity, age, and pathological gait. The book will be of considerable interest to physiology, biology and physics students, and provides researchers with stimuli for further experimental and analytical work.

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