Clinical physiology made ridiculously simple

 Physiology  Comments Off on Clinical physiology made ridiculously simple
Sep 122019
 

A brief, to-the-point presentation of the most important points in clinical physiology. Enables the reader to see cardio-pulmonary-renal physiology as well as immunology and other areas as a clear conceptual whole.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Chlamydia trachomatis: Methods and Protocols

 Miscellaneous  Comments Off on Chlamydia trachomatis: Methods and Protocols
Sep 122019
 

This book explores cutting-edge methods to work with the notoriously difficult, but highly prevalent, obligate intracellular pathogen, Chlamydia trachomatis. These include techniques to identify Chlamydia trachomatis in patient samples, ranging from simple point-of-care tests to whole genome sequencing; methods for propagation of strains in both cell culture and animal models; techniques to manipulate Chlamydia trachomatis in molecular genetic methodologies; a high-throughput screening method for testing new potential drugs against intracellular bacteria; a screen for antibiotic resistance; methods for labeling and enumeration; and descriptions of genotyping technologies, as well as dual RNA-Seq transcriptional profiling.
Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative, practical, and relevant, Chlamydia trachomatis: Methods and Protocols serves as an ideal reference for scientists searching for a better understanding of the pathogen, allowing for the development of improved treatment regimens and the discovery of new drugs.

GET IT FREE HERE

https://nitroflare.com/view/0E59C2E6CCC40A7/1493996932.epub

https://nitroflare.com/view/76B7F122AB97F67/1493996932.pdf

ALTERNATIVE LINK

https://filejoker.net/mdi8jxygzowl

https://filejoker.net/ywbq59eaalvm

Share Button

Centenarians: An Example of Positive Biology

 Miscellaneous  Comments Off on Centenarians: An Example of Positive Biology
Sep 122019
 


This state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology.
The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies.

Centenarians have reached the extreme limits of human life span. Those in relatively good health, who are able to perform their routine daily tasks, are the best examples of extreme longevity, representing selected individuals in which the appearance of major age-related diseases – including cancer and cardiovascular diseases – has been consistently delayed or avoided.
The relationship between causality and chance is an open discussion topic in many disciplines. In particular, ageing, the related diseases, and longevity are difficult to define as a consequence of causality, chance or both. Discussing the relevance of these different factors in the attainment of longevity, the book gathers contributions on genetic, epigenetic and phenotypic aspects of centenarians.

The “positive biology” approach is applied to clarify the causes of positive phenotypes, as well as to explain the biological mechanisms of health and well-being with the aim of preventing and/or reducing frailty and disability in the elderly.

GET IT FREE HERE

https://nitroflare.com/view/08C8BFA86780BBF/3030207617.epub

https://nitroflare.com/view/91F6E83E83D006B/3030207617.pdf

ALTERNATIVE LINK

https://filejoker.net/uwys28kizp7e

https://filejoker.net/wh210ywgenm2

Share Button

Infectious Diseases in Solid-Organ Transplant Recipients: A practical approach

 Infectious Diseases  Comments Off on Infectious Diseases in Solid-Organ Transplant Recipients: A practical approach
Sep 122019
 

This book describes a practical approach to the diagnosis, management, and prevention of infectious complications in solid-organ transplant (SOT) candidates and recipients, based on both up-to-date clinical evidence and state of the art expert opinion from world-renowned experts in the field. The book is divided into three parts, the first of which explains risk assessment and the general approach to infectious diseases in the pre-, peri-, and early and late post-transplant periods. The remaining two sections address the prevention and treatment of infection with particular pathogens and the management of specific syndromes, such as pneumonia, CNS infections, UTIs, and skin infections.
Infections in SOT recipients – often due to multidrug-resistant organisms – represent a major challenge. Preventive strategies need to be adapted according to the type of allograft and period after transplantation. Moreover, toxicity and drug interaction with immunosuppressive drugs must be taken into consideration when treating infectious complications. In explaining in depth how best to ensure allograft and patient survival, this book will be of value to infectious disease specialists and transplant physicians at all levels of experience

GET IT FREE HERE

https://nitroflare.com/view/1DC8E2411FA5942/3030153932.epub

https://nitroflare.com/view/2BCEB1CD19F36D6/3030153932.pdf

ALTERNATIVE LINK

https://filejoker.net/fxv0h1wzv6sc

https://filejoker.net/vkehgtlh9atm

Share Button

Current Surgical Guidelines

 Surgery  Comments Off on Current Surgical Guidelines
Sep 122019
 

This handbook summarizes currently available surgical guidelines and clearly presents them in one concise reference source. Further enhanced with diagrams, algorithms, audit tools, and user-friendly statistics, it helps to make surgical practice a well-informed and enjoyable learning experience. This book provides a reference for those embarking on their surgical training, yet is also valuable as an aide-memoire for more senior surgical staff.

Current Surgical Guidelines covers the main conditions requiring surgery, such as breast cancer, foreign body ingestion, peptic ulcers, and vascular diseases, focusing on the evidence and selection criteria which determine the best action to take. Recommendations have been graded according to relevant current guidelines and all benefits/risk decision recommendations have been supported by easy-to-digest facts and figures.

GET IT FREE HERE

https://nitroflare.com/view/ED12AF31B396B47/0199558272.pdf

ALTERNATIVE LINK

https://filejoker.net/n4sr379q7g58

Share Button

Heart Disease

 Cardiovascular  Comments Off on Heart Disease
Sep 122019
 


Despite great advances in prevention and in improving outcomes, heart disease remains a major source of morbidity and mortality in the Western world and, increasingly, in developing countries. The emotional impact of a diagnosis of heart disease can be significant, often increasing cardiac symptoms such as chest pain or palpitations. This addition to The Facts series stresses the importance and feasibility of primary prevention by appropriate life-style changes, whilst helping the reader to understand and cope with existing heart disease.

The book is structured to provide information on topics ranging from basic cardiovascular anatomy and physiology – as needed to understand the various pathologies discussed – to symptoms, clinical situations, investigations and available treatments. Beside medical information, the reader will find practical advice on how to communicate with the cardiologist, and how to prepare for certain tests. A glossary with commonly encountered medical terms is also included.

Although targeted mainly at cardiac patients with heart disease and their families, this book will also be useful for paramedics, specialist nurses, support groups, GPs and all those involved in treating heart patients in the community.

GET IT FREE HERE

https://nitroflare.com/view/3F02A6532D22D34/0199582815.pdf

ALTERNATIVE LINK

https://filejoker.net/jrv13lfdob4k

Share Button

Drugs in Palliative Care

 Palliative Medicine  Comments Off on Drugs in Palliative Care
Sep 122019
 

While palliative care has adopted a holistic approach to treatment, medication driven symptom management ostensibly forms the critical aspect of care. Pharmacological therapy can be extremely complex because these patients often have co-existing medical conditions in addition to symptoms caused by their terminal disease. The resulting polypharmacy can be daunting for professionals and can negatively impact on effectiveness of care.

The practitioner requires a simple, easy to navigate reference source that provides succinct and pertinent drug information. This detailed yet concise handbook will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information. It begins with an overview of pharmacology and prescribing advice then contains over 100 entries of palliative care drugs, in an easy to use A-Z format.

GET IT FREE HERE

https://nitroflare.com/view/5BDAA8074026525/0199563977.pdf

ALTERNATIVE LINK

https://filejoker.net/bymxxwks79re

Share Button

Why Millions Survive Cancer: The Successes of Science

 Oncology  Comments Off on Why Millions Survive Cancer: The Successes of Science
Sep 122019
 

More than 12 million cancer survivors just in the United States alone are alive today as a result of the extraordinary advances in science and medicine. In Why Millions Survive Cancer, Lauren Pecorino illuminates the enormous recent progress in fighting cancer, painting an intriguing portrait of scientific breakthroughs, the leading scientists behind these key discoveries, and the steps that we can all take to reduce our exposure to cancer.

The struggle against cancer has been long and difficult, but as Pecorino shows, the tide is changing, and changing rapidly. Treatments are becoming gentler and more effective. Many newly developed drugs have fewer side effects and can be administered as a pill rather than intravenously, giving patients a better quality of life. Better response rates are occurring for treatments that are targeted against the genetic characteristics of a tumor. Advances in instrumentation, robotics and imaging have led to more precise and less invasive surgical procedures. And public awareness about carcinogens is spreading and, increasingly, people are avoiding cigarettes, alcohol, and excessive exposure to the sun. As Pecorino discusses these exciting new developments, she provides readers with fascinating accounts of medical research and the discoveries we have made about the nature of cancer and the ways we can defeat it. For instance, we learn the stories behind such important new drugs as Avastin, Gardasil (the world’s first cervical cancer vaccine), Herceptin, and Gleevec, the development of which unfolded “like a fairy tale with a happy ending.”

GET IT FREE HERE

https://nitroflare.com/view/1F156E2B5E20EA7/0199580553.pdf

ALTERNATIVE LINK

https://filejoker.net/9t02ofrvp3n4

Share Button

Lung Cancer, 3 edition

 Oncology  Comments Off on Lung Cancer, 3 edition
Sep 112019
 


Lung cancer is the most common cancer affecting the industrialized world and affects the lives of thousands of people, including patients’ friends and family, every year. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in non-smokers, who account for as many as 15% of cases, is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.

The aim of this book is to give, in a clear and simple way, succinct information about all aspects of this type of cancer, with a stress on the practical side of its treatment. The book also details how care is likely to be organized and what patients can do to help themselves, both if they have the disease and also how to stop smoking.

Fully updated for this third edition, the book includes information on getting the best treatment and living with cancer, both of which are new approaches to the disease in the UK.

GET IT FREE HERE

https://nitroflare.com/view/1D04405783790A0/0199569339.pdf

ALTERNATIVE LINK

https://filejoker.net/wi4tcheaojgu

Share Button

Targeted Therapies in Breast Cancer

 Oncology  Comments Off on Targeted Therapies in Breast Cancer
Sep 112019
 

The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of breast cancer, such as trastuzamab (Herceptin, targeting HER-2 positive tumors) and lapatinib (Tykerb, targeting tumors with mutated/overexpressed EGFR 1 and 2). Other agents specifically targeting the estrogen receptor, the aromatose pathway and microtubule dynamics, fulvestrant (Faslodex, targeting the ER specifically in breast cancer cells), and letrozole (Femara, targeting the aromatose pathway), raloxifene (Evista, a selective estrogen receptor modulator), ixabepilone (Ixempra, a ?-tubulin inhibitor) have also been approved for various stages and specific settings in breast cancer treatment. The current challenges in the field include further targeting of these agents as part of specific strategies for each patient (biomarker testing, pharmacogenetics, etc.), as well as follow-up and management of adverse events.

Part of the Oxford American Pocket Notes series, this volume provides clinicians with the ultra-concise, evidence-based, current information and insight on implementing the latest treatment strategies, including targeted agents, into clinical practice. This portable volume is intended to provide quick, easily accessible guidance for the practicing oncologist, oncology care staff (including nurses and PAs) as well as the primary care practitioner, on the mechanism of action, dosing and administration and adverse effects of the approved targeted agents.

GET IT FREE HERE

https://nitroflare.com/view/E3FAB5FE23E4E9A/0199735670.pdf

ALTERNATIVE LINK

https://filejoker.net/dc3wy0yytfsr

Share Button