This book provides comprehensive knowledge about thyroid gland and highlights the recent trends in the management of thyroid dysfunctions.
Thyroid disorders are amongst the most prevalent of medical conditions possibly after diabetes. The prevalence of thyroid dysfunction in adults in the general population ranges from 1 to 10 percent, and is even higher in selected groups. In the United Kingdom, 1–2% of the adult population is found to have thyroid dysfunction. It is interesting to note that thyroxin is the sixth most commonly dispensed drug in Scotland. Virtually all studies report higher prevalence rates for hypothyroidism in women and with advancing age.
Abnormal thyroid functions have important public health consequences. Suppressed TSH levels have been associated with decreased bone density and with an increased risk of atrial fibrillation and premature atrial beat. It has been known for decades that overt hypothyroidism contributes to elevated serum cholesterol levels and cardiovascular risk and recent studies suggest this may also be true with subclinical hypothyroidism?.
By (author): Michael J. Gonzalez, Jorge R. Miranda-Massari
Research on vitamin C and its effects on cancer is growing in popularity around the world as positive research continues to accumulate building a stronger case for its effectiveness. This concise SpringerBrief on Vitamin C and Cancer presents the latest findings on how vitamin C induces apoptosis. A high concentration of vitamin C allows for ascorbate to generate hydrogen peroxide in tissue that can selectively kill cancer cells. Research has confirmed that high-dose vitamin C is cytotoxic to a wide variety of cancer cell lines, and that it also boosts the anti-cancer activity of several common chemotherapy drugs. Vitamin C also does more than just kill cancer cells. It boosts immunity by stimulating collagen formation to help the body wall off the tumor. It inhibits hyaluronidase, an enzyme that tumors use to metastasize and invade other organs throughout the body. This concise and up-to-date Brief is geared towards cancer researchers and scientists, as well as physicians interested in the basic science and the translational potential of vitamin C in cancer therapeutics.
This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer?statistics and epidemiology of lung cancer?along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer?immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
Features: Used Book in Good Condition By (author): Stephen Barrett, William London, Manfred Kroger, Harriet Hall, Robert Baratz
The most comprehensive consumer health text available, Consumer Health: A Guide to Intelligent Decisions offers a panoramic view of the health marketplace. You’ll learn how to sharpen your critical consumer skills so you can distinguish valid health claims from those that are fraudulent or misleading. By offering science-based facts and guidelines, Consumer Health provides the tools you need to make smart decisions about health-care products and services for yourself and your family.
In the emergency and trauma setting, accurate and consistent interpretation of imaging studies are critical to the care of acutely ill and injured patients. This book offers a comprehensive review of acute pathologies commonly encountered in the emergency room as diagnosed by radiologic imaging. It is organized by anatomical sections that present the primary ER imaging areas of the acute abdomen, pelvis, thorax, neck, head, brain and spine, and osseous structures. For each section, the common diagnoses are concisely described and are accompanied by relevant clinical facts and key teaching points that emphasize the importance of radiologic interpretation in clinical patient management. The role of modalities such as plain radiography, computed tomography, ultrasound, magnetic resonance imaging, and nuclear medicine imaging in managing emergency conditions is highlighted. The Second Edition is thoroughly updated and includes over 400 images and multiple choice questions in each chapter. Emphasizing the core concepts in emergency radiology, this book is a valuable resource for radiologists, residents, and fellows.
Surgical and anesthetic techniques have evolved to allow a growing number of older adults to undergo surgery, and current estimates are that 50% of Americans over the age of 65 years old will have an operation. However, as the knowledge regarding perioperative care of the elderly surgical patient grows, so do the questions. In this edition, each chapter includes a section entitled “Gaps in Our Knowledge,” meant to highlight areas in which research is needed, as well as hopefully inspire readers to begin solving some of these questions themselves. Building upon the strong foundation of the first two editions, Geriatric Anesthesiology, 3rd edition also assembles the most up-to-date information in geriatric anesthesia and provides anesthesiologists with important new developments.Topics covered include several new chapters that reflect the evolution of multidisciplinary geriatric care throughout the perioperative continuum, as well as the growing body of literature related to prehabilitation. In addition, discussion of the surgeon’s perspective and geriatrician’s perspective on surgery in the geriatric population is covered, as well as the systematic physiologic changes associated with aging and the pharmacologic considerations for the geriatric patient undergoing procedures. Finally, the last section discusses postoperative care specific to the geriatric population, including acute pain management, ICU management, recent evidence and up-to-date practice regarding delirium and postoperative cognitive dysfunction, and palliative care.
This richly illustrated book will help presurgically diagnose pediatric/young adult tumors. The content is divided into two parts. The first part shows step-by-step how to perform a small volume specimen such as fine needle aspiration/core needle biopsy and how to correlate the morphology with the clinical, radiological, and/or molecular information. In turn, the second part presents a comprehensive overview of the various tumor entities. The content represents diagnostic modalities from the major diagnostic centers worldwide, and is supplemented by the authors` 25 years of experience in diagnosing pediatric tumors. This book will successfully guide practitioners, researchers and oncology pediatricians through the process of sample harvesting and diagnosing.
Pediatric tumors represent a large variety of lesions including pseudotumors of inflammatory and non-inflammatory origin, various types of lympadenopathy, benign lesions, specific sarcomas, and blastemal malignancies. These age-specific and histotype-specific tumors of various origin, evolution and prognosis are often characteristic in morphological and molecular levels, making their diagnosis highly specialized.
Features: Ships from Vermont By (author): Travis Christofferson
With a new foreword by Dr. Dominic D’Agostino, PhD and epilogue by the author
A masterful synchronization of history and cutting-edge science shines new light on humanity’s darkest diagnosis.
In the wake of the Cancer Genome Atlas project’s failure to provide a legible roadmap to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease. Tripping over the Truth follows the story of cancer’s proposed metabolic origin from the vaunted halls of the German scientific golden age to modern laboratories around the world. The reader is taken on a journey through time and science that results in an unlikely connecting of the dots with profound therapeutic implications.
Transporting us on a rich narrative of humanity’s struggle to understand the cellular events that conspire to form malignancy, Tripping over the Truth reads like a detective novel, full of twists and cover-ups, blind-alleys and striking moments of discovery by men and women with uncommon vision, grit, and fortitude. Ultimately, Christofferson arrives at a conclusion that challenges everything we thought we knew about the disease, suggesting the reason for the failed war against cancer stems from a flawed paradigm that categorizes cancer as an exclusively genetic disease.
For anyone affected by this terrifying disease and the physicians who struggle to treat it, this book provides a fresh and hopeful perspective. It explores the new and exciting non-toxic therapies born from the emerging metabolic theory of cancer. These therapies may one day prove to be a turning point in the struggle against our ancient enemy. We are shown how the metabolic theory redraws the battle map, directing researchers to approach cancer treatment from a different angle, framing it more like a gentle rehabilitation rather than all-out combat. In a sharp departure from the current “targeted” revolution occurring in cancer pharmaceuticals, the metabolic therapies highlighted have one striking feature that sets them apart?the potential to treat all types of cancer because they exploit the one weakness that is common to every cancer cell: dysfunctional metabolism.
With contributions from Thomas Seyfried, PhD, author of Cancer as a Metabolic Disease; Miriam Kalamian, EdM, MS, CNS, author of Keto for Cancer; and Beth Zupec Kania, consultant nutritionist of The Charlie Foundation.