Innovative Implantation Technique: Bag-in-the-Lens Cataract Surgery

 Surgery  Comments Off on Innovative Implantation Technique: Bag-in-the-Lens Cataract Surgery
Mar 232019
 

This book provides a complete overview of the bag-in-the-lens implantation technique written by the pioneering force herself. The technique first developed for the adults and later for paediatrics has had overwhelmingly positive outcomes in reduction of posterior capsular opacification and stability. Nowadays, it is used as a primary approach in all patients with cataract. The initial version of the bag-in-the-lens implant is a monofocal spherical hydrophilic intraocular lens comprised of a 5mm bi-convex optic with two elliptical plane haptics. Bag-in-the-Lens Cataract Surgery guides through the steps required to achieve successful implantation in a concise and highly illustrated format to portray how to effectively perform this surgery. The toric version was launched in 2009 and the diffractive version is on its way.

New and experienced ophthalmic surgeons will find this guide to be an indispensable resource for utilizing this technique to successfully treat adult and paediatric cataract patients in their daily clinical practice.

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Applied Law & Ethics for Health Professionals, Second Edition

 Miscellaneous  Comments Off on Applied Law & Ethics for Health Professionals, Second Edition
Mar 232019
 

by Carla Caldwell Stanford (Author), Valerie J. Connor (Author)

On a daily basis, healthcare professionals are faced with many ethical situations along with legal implications. Applied Law and Ethics for Health Professionals, Second Edition tackles ethical situations and the potential legal impacts that many healthcare professionals may face in their careers and asks them to consider their own personal values system and use reasoning skills to come to an informed outcome. Modern cases and topics are discussed, offering real-world ethical and legal accounts that may impact professionals in the field. As the text concludes, readers are again asked to gauge their growth, exploring their newly formed knowledge, values, and opinions on healthcare ethics

About the Author
Professor, St. Joseph’s College of Maine

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The Making of a Neuromorphic Visual System

 Neurology/Neurosurgery  Comments Off on The Making of a Neuromorphic Visual System
Mar 222019
 

The reader is presented an approach to the construction of a visual system, which is behaviorally, computationally and neurally motivated. The central goal is to characterize the process of visual categorization and to find a suitable representation format that can successfully deal with the structural variability existent within visual categories. It does not define such representations a priori but attempts to show directions on how to gradually work towards them. The book reviews past and existent theories of visual object and shape recognition in the fields of computer vision, neuroscience and psychology. The entire range of computations is discussed, as for example contour extraction in retinal circuits, orientation determination in cortical networks, position and scale independence of shape, as well as the issue of object and shape representation in a neural substrate. Region-based approaches are discussed and are modeled with wave-propagating networks. It is demonstrated how those networks operate on gray-scale images. A completely novel shape recognition architecture is proposed that can recognize simple shapes under various degraded conditions. It is discussed how such networks can be used for constructing basic-level object representations. It is envisioned how those networks can be implemented using the method of neuromorphic engineering, an analog electronic hardware substrate than can run neural computations in real-time and with little power.
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Applied Medical Image Processing: A Basic Course, Second Edition

 Radiology  Comments Off on Applied Medical Image Processing: A Basic Course, Second Edition
Mar 222019
 

A widely used, classroom-tested text, Applied Medical Image Processing: A Basic Course delivers an ideal introduction to image processing in medicine, emphasizing the clinical relevance and special requirements of the field. Avoiding excessive mathematical formalisms, the book presents key principles by implementing algorithms from scratch and using simple MATLAB®/Octave scripts with image data and illustrations on an accompanying CD-ROM or companion website. Organized as a complete textbook, it provides an overview of the physics of medical image processing and discusses image formats and data storage, intensity transforms, filtering of images and applications of the Fourier transform, three-dimensional spatial transforms, volume rendering, image registration, and tomographic reconstruction.
This Second Edition of the bestseller:
• Contains two brand-new chapters on clinical applications and image-guided therapy
• Devotes more attention to the subject of color space
• Includes additional examples from radiology, internal medicine, surgery, and radiation therapy
• Incorporates freely available programs in the public domain (e.g., GIMP, 3DSlicer, and ImageJ) when applicable
Beneficial to students of medical physics, biomedical engineering, computer science, applied mathematics, and related fields, as well as medical physicists, radiographers, radiologists, and other professionals, Applied Medical Image Processing: A Basic Course, Second Edition is fully updated and expanded to ensure a perfect blend of theory and practice.

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Design and Analysis of Clinical Trials for Predictive Medicine

 Miscellaneous  Comments Off on Design and Analysis of Clinical Trials for Predictive Medicine
Mar 222019
 

An emerging clinical trials paradigm for predictive medicine involves the development of molecular diagnostics to enable the prediction of the effects of treatment or outcomes of individual patients. This book offers statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics. The book explains how to identify molecular biomarkers using DNA microarrays, validate the developed biomarkers, and confirm their clinical utility in randomized clinical trials.

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Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body

 Toxicology  Comments Off on Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body
Mar 212019
 

Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body provides a detailed overview of the disposition of nanoproducts within the body, with a special focus on the respiratory and olfactory routes of nanoproduct administration, buccal exposure and the ingestion of nanoproducts, the integumentary system (formed by the skin, hair, nails, and associated glands), the ocular route, the systemic route, and toxicology as it relates to the nanoscale world.
Offering an interdisciplinary, big-picture view of the current and future state of nanotechnology, this book:
• Identifies key points for the entry of nanoproducts, nanomedicines, and other nanoscale structures into the body
• Reviews the bodily administration and subsequent disposition of nanoproducts via various exposure routes
• Describes the intravenous route of administration for the therapeutic management of ocular disease
• Discusses practical nanoproduct and nanomedicine applications, disposition, and toxicology
• Summarizes various toxicological principles and the testing of nanoproducts
Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body addresses the scope of practical nanoparticle applications in academic research as well as industrial investigation, where “practical” is defined as advantageous in all aspects of nanoproduct disposition, efficacy, and toxicology. The book’s goal is to introduce potentially beneficial applications and exciting topics regarding nanoproducts to a variety of professional and general readers.

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Nutrition, Fertility, and Human Reproductive Function

 Nutrition  Comments Off on Nutrition, Fertility, and Human Reproductive Function
Mar 212019
 

One in six couples around the world experience infertility. Before undertaking expensive and intrusive assisted reproductive treatment such as in vitro fertilization, many seek advice from their physicians or dietitians on what foods and supplements might enhance their fertility. But health practitioners are often ill equipped to provide dietary recommendations in a scientifically based manner. Nutrition, Fertility, and Human Reproductive Function provides a comprehensive guide to clinicians on how they can best advise their patients to optimise fertility and reproductive function through optimal nutrition.

Taking a holistic or “whole-of-life” approach, the book reviews the role of nutrition in human fertility and explores its effect on male and female reproductive physiology. Problem-orientated topics are arranged in chapters that each cover a specific clinical topic of interest, allowing easy reference by the practicing clinician. From the female perspective, the book covers the role of nutrition on essential reproductive processes such as ovulation, early embryo development, implantation, and sexual function, together with nutrition’s influence on the duration of the reproductive life span. In the male context, it examines the effect of nutrition on hormone and sperm production as well as sexual function. The book also includes information on evidence-based complementary health approaches such as Traditional Chinese Medicine (TCM) and naturopathy.

This book draws on the wide experience of several respected leaders in clinical nutrition who combine research expertise with clinical insight. The information contained herein will enable clinicians to make the best recommendations for their patients for optimising fertility.

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Brachytherapy, Second Edition: Applications and Techniques

 Radiology  Comments Off on Brachytherapy, Second Edition: Applications and Techniques
Mar 212019
 

Since the first edition was published in 2006, Phillip M. Devlin’s Brachytherapy has been acknowledged as the essential book on the practice. In this updated new edition, all chapters covering cancer sites have been significantly revised. Organized for specialists in several fields, Brachytherapy contains site-specific chapters that discuss how the evolving role of advanced image guidance has demonstrated greater efficacy and less toxicity. Clinical vignettes with images now accompany all site-specific chapters. The chapter on prostate brachytherapy has been expanded to include other indications in the genitourinary system, and there are two entirely new chapters–one chronicling the history of brachytherapy and the other detailing the emergence of skin brachytherapy.

Dr. Devlin, a leading world authority on brachytherapy, has assembled other leaders in the field from world-renowned radiation oncology programs to enrich this comprehensive text. From new data on medical outcomes to the costs and benefits of running a brachytherapy practice, Brachytherapy, Second Edition is the first and last word on what still is considered the most conformal radiotherapy technique in the field.

In the new edition:

Over 300 images accompany the chapter text and clinical vignettes
Essential tables and spreadsheets enhance the chapter on running a brachytherapy practice
Ten years of technological advancements are assimilated and reviewed in each site-specific chapter

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Immune System Modelling and Simulation

 Immunology  Comments Off on Immune System Modelling and Simulation
Mar 212019
 

The book describes a computational model of the immune system reaction, C-ImmSim, built along the lines of the computer model known as the Celada-Seiden model (CS-model). The computational counterpart of the CS-model is called IMMSIM which stands for IMMune system SIMulator. IMMSIM was written in 1992 by the physicist Phil E. Seiden and the immunologist Franco Celada. This model was built around the idea of developing a computerized system to perform experiments similar in vivo experiments; a tool developed to help biologists testing theories and hypothesis about how the immune system works.

C-ImmSim is best viewed as a collection of models in a single program. It incorporates the principal core facts of today’s immunological knowledge, such as the diversity of specific elements, MHC restriction, clonal selection, thymic education of T cells, antigen processing and presentation (both the cytosolic and endocytic pathways are implemented), cell-cell cooperation, homeostasis of cells created by the bone marrow, hyper mutation of antibodies, maturation of the cellular and humoral response, and memory. Besides, an antigen can represent a bacterium, a virus, or an allergen or a tumor cell. C-ImmSim has been recently customized to simulate the HIV-1 infection. Moreover, it can simulate the immunotherapy for cancer. These features are all present in the code and people can choose to turn them on and off at compiling time.

The book presents the basic model as well as the various customizations to implement the description of different diseases and the way they have been used in practice to produce new knowledge either from hypothesis or from lab-experiment data. In this respect, the book can be used as a practical guide to implement a computational model with which to study a specific disease and to try to address realistic clinical questions.

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PET/CT in Brain Disorders

 Neurology/Neurosurgery  Comments Off on PET/CT in Brain Disorders
Mar 212019
 

This well-illustrated pocket book offers up-to-date guidance on the clinical and research applications of PET/CT in the most common neurological and neuro-oncological disorders. The opening chapters cover the pros and cons of widely used radiological imaging techniques, scanners, and radiopharmaceuticals, with emphasis on the state of the art hybrid modalities, primarily PET/CT but also PET/MRI. Helpful information is provided on the clinical and research tracers used in neurodegenerative diseases, movement disorders, epilepsy and brain tumours. These four killers are then discussed in detail, highlighting the role of PET/CT and targeted tracers in their assessment and in radiotherapy planning. In addition, the clinical applications of PET/MRI are considered. Throughout, many images are included to better explain the diseases and the role of hybrid imaging, and the final chapter presents a large sample of teaching cases and files that will assist in daily clinical practice. The book has been compiled under the auspices of the British Nuclear Medicine Society. It will be an excellent asset for nuclear medicine physicians, radiologists, radiographers, neurologists and neurosurgeons.
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