Here’s the most clinically oriented critical care text focusing on the adult patient. In full-color and superbly illustrated with clinical photographs, imaging studies, and management algorithms, and with a broad multidisciplinary focus, this text will help you enhance your skills at any level of training.

Stands alone as a clinically oriented comprehensive reference.
Completely updated and authorship expanded to reflect the evolution in critical care practice.
In color for the first time, with new color schematics and treatment algorithms for greater ease of reference.
Utilizes key points lists at the end of chapter, to help you make decisions rapidly and easily.
Delivers key references that list other useful resources for information.

Includes these seven new chapters to keep you on the cutting edge of your specialty:
Assessment of Cardiac Filling and Blood Flow
Mechanical Ventilation of Obstructive Airways Disease
Mechanical Ventilation of Acute Respiratory Distress Syndrome
Severe Sepsis and Multiple Organ Dysfunction
Stroke
Delirium, Psychosis, Sleep and Depression in the ICU
ICU Education




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Review

“This is an excellent book that should be used by everyone starting to learn histology. It is superbly simple and colourful with informative diagrams that are clearly labelled! This book makes histology enjoyable: much better than staring for hours on end down a microscope and not knowing what you are looking at! I like the way it divides the sections into the different body systems. The index is very useful. High-quality illustrations are provided in this book and the printing quality is excellent. I will happily recommend it to all science and medical students!”

BMA Awards 2007
“.concise relevant text with excellent photographs, excellently reproduced.Wheater’s remains an excellent book and is highly recommended.”

Professor JA Lee, ACP News
This best-selling atlas contains over 900 images and illustrations to help you learn and review the microstructure of human tissues. The book starts with a section on general cell structure and replication. Basic tissue types are covered in the following section, and the third section presents the microstructures of each of the major body systems. The highest -quality color light micrographs and electron micrograph images are accompanied by concise text and captions which explain the appearance, function, and clinical significance of each image. The accompanying website lets you view all the images from the atlas with a “virtual microscope”, allowing you to view the image at a variety of pre-set magnifications.
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Wheater's Functional Histology: A Text and Colour Atlas, 5th Edition (Paperback)

By (author) Barbara Young, James S. Lowe, Alan Stevens, John W. Heath

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The Handbook on Parathyroid Diseases presents a comprehensive and concise overview of our current knowledge in the area of parathyroid function, hormone regulation and disease states. The Handbook educates the reader using a case-based approach presenting current evidence in the field. The material is presented in an easy to read and understandable language and uses a plethora of tables and text boxes where possible. Complex concepts are conveyed in simple and clear language. Leading international experts contribute to this state of the art book providing a true depth of knowledge and practicality.
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Bone age assessment, a crucial part of the diagnosis and management of pediatric growth disorders as well as the timing of certain pediatric orthopedic procedures, has for decades depended on the meticulous examination of plain radiographs. Examining the subtle changes present within the maturing human hand often proves to be challenging and time-consuming.

Building on the popular Greulich and Pyle atlas, this book modernizes the method for pediatric skeletal maturity determination. It offers a wealth of images, carefully mined from thousands of digital radiographs from University of Virginia’s Picture Archiving and Communication System (PACS), edited to best demonstrate important developmental bone features, and organized by age and sex for rapid reference. To expedite learning and clinical image analysis, images come in pairs: annotated and unannotated, for easy comparison. Succinct annotations on the images replace lengthy text to provide a quicker and clearer understanding of the skeletal age. These annotations highlight important and subtle features to help distinguish images that otherwise look superficially alike. The result is an atlas of exceptionally high quality skeletal radiographic standards that capture both the major and finer details of the accepted standards of Greulich and Pyle.

The user-friendly format of this book enables a faster, more accurate, and more educational approach to determining skeletal maturity. The Digital Bone Age Companion packaged with the book is a computer program that facilitates viewing of the atlas images in digital format. Users can easily zoom in on radiographic features, set image level and width to their preference, and compare two or three reference standards side-by-side for difficult cases. Most importantly, the program expedites evaluation, optimizes workflow, and minimizes user-introduced errors with the reliable bone age calculator and built-in report generator. The digital format may also be available for integration with your Radiology Information System (RIS) for further workflow enhancement.

Given the broad application of pediatric bone aging, Skeletal Development of the Hand and Wrist is not only intended for practicing and training radiologists, but for all of those who employ bone age studies as part of their practice



Skeletal Development of the Hand and Wrist: A Radiographic Atlas and Digital Bone Age Companion (Hardcover)

By (author) Cree M. Gaskin, S. Lowell Kahn, J. Christoper Bertozzi, Paul M. Bunch

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This pocket revision guide is a must for all medical students preparing for a major exam in clinical surgery or needing a rapid reminder during a clinical attachment.

Rapid Surgery is the sixth title in the new Rapid series and is the ideal companion for medical students and junior doctors, covering key facts in a simple and memorable fashion, using a mnemonic to aid recall. The text contains over 100 common surgical conditions and over 30 practical surgical procedures. The book contains over 35 illustrations and radiographs of numerous conditions to help aid in consolidating memory. Arranged in A-Z format, each topic is covered using the same headings – Definition, Aetiology, Associations / Risk Factors, Epidemiology, History, Examination, Pathology, Investigations, Management, Complications and Prognosis.

The surgical procedures are divided using the headings – Indication, Anatomy, Preoperative Investigations, Procedure, Complications and Prognosis.

*A-Z format for easy and rapid access to information
*Strict organisation of facts on each page following the new Rapid series mnemonic with one side set aside for each condition
*Includes drawings to help vizualise difficult concepts
*Handy pocketbook for quick reference in a surgical setting
*Written by students and junior doctors with expert editorial advice



Rapid Surgery (Paperback)

By (author) Ebube Obi, Cara R. Baker, Mark Teo, James T. H. Teo

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How often have you been confronted with an image on a thoracic CT exam where you knew it didn’t look ‘normal’, but you weren’t sure whether it was ‘abnormal’ either? And if it is abnormal, is there a specific diagnosis you should be able to make directly off the images? Pearls and Pitfalls in Chest Imaging is your one-stop resource to answer questions such as: Is this a normal variant or a disease-related abnormality? Are these findings specific for an uncommon disease and if so what is the diagnosis? Is this set of findings strongly suggestive of a diagnosis? Which additional imaging test will allow me to be confident in that diagnosis? Could the ‘abnormality’ be due to an artifact mimicking disease? Written by leading thoracic radiologists and with concise, image-rich descriptions, Pearls and Pitfalls in Chest Imaging is an invaluable diagnostic tool for every radiologist.
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This focused book deals clearly and concisely with the principles of management of patients with acute ischemic stroke (AIS). It emphasizes the published and verifiable evidence in support of these principles, and highlights the areas of limited evidence. Best evidence is provided for the current standard treatment of acute ischemic stroke, including intravenous chemical thrombolysis, intra-arterial approaches, blood pressure management, and anti-thrombotic therapy. More modern techniques are also described, such as the use of mechanical devices to evacuate a thrombus, induced hypertension, hyper-oxygenation (hyperoxia), and neuroprotective or neuroregeneration agents.

Hallmark features include:

* Focused on acute ischemic stroke, the most rapidly growing area of stroke management
* Evidence based: Provides best evidence for treatment
* Clearly discusses areas and topics where best evidence has not yet been established
* Lays out treatment plans and protocols in handbook fashion for ease of use and reference, even in emergency situations
* Includes latest and cutting-edge techniques and equipment for dealing with AIS

Acute Ischemic Stroke: An Evidence-based Approach is an indispensable reference work for neurologists, neurocritical care medics, intensivists, hospitalists, emergency room physicians, neurology residents and fellows. It is also a helpful resource for medical students, physician assistants, and nurse practitioners in hospital and neurocritical care facilities.
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The Handbook of Cutaneous Medicine and Surgery is written for dermatology residents and clerkship students; containing up-to-date and easily accessible medical and surgical information. It is a quick reference on a wide range of dermatologic diseases–including concise clinical information on diagnostic features, lab findings and practical management as well as key surgical anatomy and pearls on lasers, basic science and pharmacology. Also featured are notable dermatologic/dermpath mneumonics and a comprehensive quick reference of cutaneous disease and syndrome associations.
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This book traces the early history and provides knowledge on demonstration of principles from ancient to the most recent embryo studies amidst the unresolved scientific and ethical issues.

Contents

Preface

Part 1 Introduction

1 Introduction – Developmental Overview of the Human Embryo

2 Presenting Human Embryology in an International Open-Access Reference Centre (HERC)

Part 2 Implantation

3 Optimal Environment for the Implantation of Human Embryo

4 Immune Regulation of Human Embryo Implantation by Circulating Blood Cells

5 The Future of Human Embryo Culture Media – Or Have We Reached the Ceiling?

6 Benzo[a]pyrene and Human Embryo

Part 3 Organogenesis and Genetics

7 Developmental Anatomy of the Human Embryo – 3D-lmaging and Analytical Techniques

8 Cardiovascular Development in the First Trimester

9 Development. Differentiation and Derivatives of the Wolffian and Mullerian Ducts

10 Cytogenetic Analysis of Spontaneous Miscarriage

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BRS Gross Anatomy presents a concise review of human anatomy for students in medical, dental, graduate, physician assistant, physical therapy, and other health science programs. Condensed descriptions, full-color illustrations, and concise outline format combine with board-style questions and a comprehensive exam at the end of the book for a comprehensive, clinically relevant review for USMLE and other board exams in health-related professions. Although in summary form, coverage is similar to standard textbooks for human anatomy courses.
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BRS Gross Anatomy (Board Review Series) (Paperback)

By (author) Kyung Won Chung, Harold M. Chung

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There is no dearth of high-quality books on renal biopsy and pathology in the market. These are either single author or multi-author books, written by world authorities in their respective areas, mostly from the developed world. The vast scholarly potential of authors in the developing countries remains underutilized. Most of the books share the classical monotony of the topics or subjects covered in the book. The current book is a unique adventure in that it bears a truly international outlook and incorporates a variety of topics, which make the book a very interesting project. The authors of the present book hail not only from the developed world, but also many developing countries. The authors belong not only to US but also to Europe as well as to Pakistan and Japan. The scientific content of the book is equally varied, spanning the spectrum of technical issues of biopsy procurement, to pathological examination, to individual disease entities, renal graft pathology, pathophysiology of renal disorders, to practice guidelines

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This book will help get us and patients enlightened with the new developments on the contemporary pediatric issues. In this book volume, beyond classical themes, a different approach was made to current pediatric issues and topics. This volume describes nutritional infant health and some interesting topics from pediatric subspecialties such as cardiology, hemato-oncology and infectious diseases.

Contents

Preface

Part 1 The Public and Pediatrics

1 Paediatrics, the People and Politicians in Spain – History, Development, Reality and Future

Part 2 Nutritional Health

2 Feeding and Fluids in the Premature and Sick Newborn in the Low-Middle Income Countries

3 The Long-Term Effects of Breastfeeding on Development

4 Breastfeeding and Infant Growth

5 Nutrition in Healthy Children

6 The Growth and Development in Healthy Child

7 Probiotics for Autoimmune Diseases: Is There a Benefit?

Part 3 Pediatric Cardiology

8 Infants Born with Intrauterine Growth Restriction: Renal and Cardiovascular Follow-Up

9 Pediatric Cardiac Surgery: A Challenge of Skill and Creativity in Constant Search Results

Part 4 Pediatric Hemato-Oncology

10 Alpha Thalassemia Disorders

11 Neuroblastoma and Whole Genome Searches

12 Neuroblastoma – Molecular Basis for Diagnosis and Staging System

13 Fertility and Fecundity After Chemotherapy for Childhood Cancer

14 Fatigue in Pediatric Oncology Patients

15 Cancer Illness in Children and the Socioeconomic Resources of Parents

Part 5 Pediatric Infectious Diseases

16 Fungal Infections in Patients of Paediatric Age

17 Infantile Chronic Recurrent Parotitis (ICRP): Analysis of Changes in the Expression of Parotid Salivary Proteins Associated with the Disease

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Organized around the central theme of homeostasis, FUNDAMENTALS OF HUMAN PHYSIOLOGY is a carefully condensed version of Lauralee Sherwood’s HUMAN PHYSIOLOGY: FROM CELLS TO SYSTEMS. It provides clear, current, concise, clinically oriented coverage of physiology. Many analogies and frequent references to everyday experiences help students relate to the physiology concepts presented. Offering helpful art and pedagogical features, Sherwood promotes understanding of the basic principles and concepts of physiology rather than memorization of details and provides a foundation for future careers in the health professions.
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Fundamentals of Human Physiology (Paperback)

By (author) Lauralee Sherwood

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This book provides an up- to- date summary of many advances in our understanding of anemia, including its causes and pathogenesis, methods of diagnosis, and the morbidity and mortality associated with it. Special attention is paid to the anemia of chronic disease. Nutritional causes of anemia, especially in developing countries, are discussed. Also presented are anemias related to pregnancy, the fetus and the newborn infant.

Thus this book provides a wide coverage of anemia which should be useful to those involved in many fields of anemia from basic researchers to epidemiologists to clinical practitioners.

Contents

1 Morbidity and Mortality in Anemia

2 Erythrocyte: Programmed Cell Death

3 Phosphatidylserine Shedding from RBCs – A Mechanism of Membrane Modulation and Damage Control

4 Anemia Caused by Oxidative Stress

5 Iron and Nitric Oxide in Anemia of Chronic Disease (ACD)

6 Diagnostic Evaluation of Anaemia

7 How Can Cancer-Associated Anemia Be Moderated with Nutritional Factors and How Do Beta Vulgaris L. Ssp. Esculenta Var. Rubra Modify the Transmethylation Reaction in Erythrocytes in Cancerous Patients?

8 Anaemia in Developing Countries: Burden and Prospects of Prevention and Control

9 Nutritional Anaemia

10 Nutritional Anemia in Developing Countries

11 Risk Factors for Anemia in Preschool Children in Sub-Saharan Africa

12 Acceptance and Effect of Ferrous Fumarate Containing Micronutrient Sprinkles on Anemia, Iron Deficiency and Anthropometries in Honduran Children

13 Supplementation and Change of Nutritional Habits for the Prevention and Treatment of Iron Deficiency Anaemia in Gaza Children: A Case Study

14 Managementof Anaemia in Pregnancy

15 Clinical Management of Hemolytic Disease of the Newborn and Fetus

16 The Pathogenesis of Anaemia in African Animal Trypanosomosis

17 The Mechanisms of Anaemia in Trypanosomosis: A Review

18 Severe Malaria Anaemia in Children

19 The Effect of Retinol Supplement on Blood Cytokine Concentrations in Children with Non-Severe Malaria Vivax

20 Elevated System Energy Expenditure in Sickle Cell Anemia

21 Molecular Basis of Thalassemia

22 Paroxysmal Nocturnal Hemoglobinuria

23 Anemia in Chronic Obstructive Pulmonary Disease

24 An Emerging Face of Fanconi Anemia: Cancer

25 The Molecular Connection Between Aluminum Toxicity, Anemia, Inflammation and Obesity: Therapeutic Cues

26 Hemolysis and Anemia Induced by Dapsone

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Prescott, Harley and Klein’s 5th edition provides a balanced, comprehensive introduction to all major areas of microbiology. Because of this balance, Microbiology, 5/e is appropriate for students preparing for careers in medicine, dentistry, nursing, and allied health, as well as research, teaching, and industry. Biology and chemistry are prerequisites. The Fifth Edition has been updated extensively to reflect the latest discoveries in the field.
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Microbiology, Fifth Edition (Hardcover)

By (author) Lansing M. Prescott

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Here is a direct, highly readable way for students to gain a fundamental knowledge and basic understanding of cardiovascular physiology. Experienced practitioners will find this versatile reference to be the perfect refresher course and a convenient way to stay up-to-date on the latest research and developments in this ever-changing field.

# Provides a short, well-mapped path to mastery of concepts and functions of cardiovascular physiology
# Clarifies the details of physiologic mechanisms and their role in pathologic states
# Links cardiovascular physiology to diagnosis and treatment
# Summarizes key concepts at the end of each chapter, with pointers to the source material in the text
# Offers new information on cellular processes, blood and blood clotting, closed-system functions, electrophysiology, clinical issues such as diastolic and systolic heart failure-and MORE
# Expands coverage of growth, aging, and gender issues
# Provides an ideal quick review for the USMLE Step 1
# Reinforces learning with study questions
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Lecture Notes: Obstetrics and Gynaecology provides a concise introduction to obstetrics and gynaecology for medical students and junior doctors. Six sections examine the female development from the early years to old age. The text starts with a section on Basic Science. Self-assessment questions are found throughout the text to enhance knowledge and understanding.
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Learn. Practice. Assess.

Hole’s Human Anatomy and Physiology was created for the introductory level student and assumes no prior science knowledge by placing emphasis on the fundamentals. This new edition updates a great A&P classic while offering greater efficiencies to the user. The format for the 12th edition focuses on Learning Outcomes and Assessments. This will benefit the student along with the instructor. The 12th edition of Hole also continues to offer technology that combined with the text offer users an incredible Course Solution! Technology like Anatomy and Physiology Revealed and the new online Homework Manager bring unprecedented opportunities to the classroom whether on campus or at home!
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Hole's Human Anatomy and Physiology (Hardcover)

By (author) David Shier, Jackie Butler, Ricki Lewis

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This monograph deals with the pathophysiology of atherosclerosis with emphasis on epigenetics, metabolomics, inflammation, molecular and cellular mechanisms involved in cardiovascular disease development. This book has been written with the intention of providing new concepts about coronary artery disease pathogenesis that may link various aspects of the disease, going beyond the traditional risk factors.

Contents

Preface

Part 1 Pathogenesis

1 Gene Polymorphism and Coronary Heart Disease

2 Lipoprotein(a) Oxidation, Autoimmune and Atherosclerosis

3 ICAM-1: Contribution to Vascular Inflammation and Early Atherosclerosis

4 Molecular and Cellular Aspects of Atherosclerosis: Emerging Roles of TRPC Channels

5 Hypoxia-Regulated Pro- and Anti-Angiogenesis in the Heart

6 Paraoxonase 1 (PON 1) Activity, Polymorphisms and Coronary Artery Disease

Part 2 Acute Coronary Syndrome

7 Acute Coronary Syndrome: Pathological Findings by Means of Electron Microscopy, Advance Imaging in Cardiology

8 Shortened Activated Partial Thromboplastin Time (APTT): A Simple but Important Marker of Hypercoagulable State During Acute Coronary Event

Part 3 Cardiovascular Prevention

9 Individualized Cardiovascular Risk Assessment

10 Metabolomics in Cardiovascular Disease: Towards Clinical Application

11 Novel Regulators of Low-Density Lipoprotein Receptor and Circulating LDL-C for the Prevention and Treatment of Coronary Artery Disease

12 Serum Choline Plasmalogen is a Reliable Biomarker for Atherogenic Status

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This book contains 109 clinical cases illustrated by color photographs, diagrams and tables that will help candidates for postgraduate examinations learn how to handle the investigation and management of elderly patients. The cases cover the main modes of presentation of acute illness in old age, such as fall, confusion, incontinence, weight loss and immobility, with examples from all the major systems. The cases illustrate the complexity of diagnosis and treatment of medical illness in older people and the need to think widely and laterally when caring for such patients. The book also contains 250 ‘best of 5′ multiple choice questions and answers to reflect the current style used in postgraduate examinations.
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Rapid Review of Medicine in Old Age (Paperback)

By (author) Michael Vassallo, Stephen Allen

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Diabetes mellitus is increasing in incidence, prevalence, and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 438 million people with diabetes on a global scale. In the United States, the Centers for Disease Control calculates that 25.8 million people (or 8.3% of the population) have diabetes and nearly 2 million Americans develop diabetes each year. Thus, the burden of diabetes is enormous in terms of the magnitude of the population affected.  There has been an exciting explosion of knowledge about fundamental mechanisms related to diabetes. We have gained insights into the pathogenesis both of type 1 and type 2 diabetes, and with that, the prospect of implementing prevention strategies to delay or interdict the disease processes. Great progress has been made in islet transplantation, which offers the potential of reversing diabetes, while approaches to islet replacement by regeneration or stem cell therapy are in their infancy. Whether diabetes prevention will come from advances in understanding the processes of islet neogenesis and proliferation, from genetic engineering, or from protecting xenoislets or stem cells from immunologic attack remains unclear. All are potential avenues of pursuit. This newly revised, comprehensive, four-color Atlas of Diabetes, 4th Edition, is extensively updated with references to the current literature.  Developed by leading authorities in the field, this Atlas offers an indispensable collection of images, including algorithms, tables, charts, and schematic drawings.  It continues its role as a leading reference work and an invaluable contribution to the field.
This handbook is an invaluable resource for improving the management of diabetes. Chapters cover the fundamentals, including epidemiology, history and physical examination, and functional evaluations. Diabetes in children, adolescents, adults, and geriatrics are addressed. Differential diagnosis is emphasized, and evidence-based guidelines and patient-specific considerations aid the reader with injury evaluation and care. Notably, the book highlights the importance of understanding diabetic symptoms when determining the source of illnesses. In addition, the text presents the spectrum of treatment options for diabetes. The book is complete with appendices that explain the evidence-based approach used throughout and the science behind therapeutic modalities




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Labor and Delivery Care: A Practical Guide supports and reinforces the acquisition of the practical obstetric skills needed for aiding a successful birth.
Beginning with the most important element of successful labor care, communicating with the patient, the authors guide you through normal delivery routines and examination techniques. They then address the best approaches to the full range of challenges that can arise during labor and delivery. Throughout, the 15 chapters provide concise practical guidance with:

* algorithmic decision trees
* clinical management tips
* detailed drawings

Labor and Delivery Care: A Practical Guide provides a thorough tour-de-force of the practical obstetric skills needed for best and safest practice based on clinical experience and evidence



Labor and Delivery Care: A Practical Guide (Hardcover)

By (author) Wayne R. Cohen, Emanuel A. Friedman

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Imaging in Pediatric Pulmonology is a definitive reference to imaging and differential diagnosis for pediatric pulmonology.  Diseases and disorders seen in everyday clinical practice are featured, including infections, developmental disorders, airway abnormalities, diffuse lung diseases, focal lung diseases, and lung tumors.  Organized to support the clinical thought process, the text begins with a series of clinical algorithms that provide a starting point for formulating a diagnosis.  The physician will be able to identify the differentials by symptom complex and accordingly determine what test would be effective and how to proceed.  The balance of the book is image-based and presents a comprehensive, multi-modality approach, with an emphasis on plain film and cross-sectional imaging.  The imaging sections are correlated with pathology and clinical findings to help readers learn what the modality of choice can enable them to see.  Edited by Robert H. Cleveland, MD, Professor of Radiology at Harvard Medical School and Chief of the Division of Diagnostic Radiology at Children’s Hospital Boston, the book includes a talented group of associate editors and contributing authors who are noted experts in pathology, pulmonology, and radiology, making Imaging in Pediatric Pulmonology an ideal reference for all physicians involved in the diagnosis and treatment of pediatric pulmonary issues




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The new 12th edition of Bailey & Scott’s Diagnostic Microbiology solidifies its reputation as the classic text in the field of microbiology. This new edition features the same comprehensive, authoritative content – and adds new and updated material throughout. The team of authors includes three well-respected clinical microbiologists, all of whom have experience both in the classroom and the clinical laboratory.

* A respected author team consists of three well-respected clinical microbiologists, each of whom has experience both in the classroom and the clinical laboratory.
* Genera and Species to be Considered highlight all of the organisms to be discussed in each chapter, including the current name of the species as well as any previous names.
* Detailed hands-on procedures make the content more interesting and relevant by describing exactly what takes place in the micro lab.
* Convenient, easy-to-read tables summarize key information.
* A glossary of all of the terms is found at the back of the book for quick reference.
* Three NEW chapters:
* General Considerations and Applications of Information Provided in Bacterial Sections of Part III explains explains the criteria for organism inclusion and how it should be used.
* Bacterial Identification Flow Charts and Schemes: A Guide to Part III includes gram reaction, shape, arrangement, atmosphere preferred, oxidase and catalase reactions, among other decision points for various pathogens, creating a visual method of identifying and cross referencing organisms.
* Sentinel Laboratory Response to Bioterrorism
* A NEW section on clinical laboratory management
* More case studies help to develop critical thinking skills, with answers in an appendix.
* More photos of the major organisms have been included to help in identifying different organisms






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Evidence-Based Practice of Critical Care, edited by Drs. Clifford S. Deutschman and Patrick J. Neligan, provides objective data and expert guidance to help answer the most important questions challenging ICU physicians today. It discusses the clinical options, examines the relevant research, and presents expert recommendations on everything from acute organ failure to prevention issues. An outstanding source for “best practices” in critical care medicine, this book is a valuable framework for translating evidence into practice. It also provides access to the full text online, with regular updates to emerging clinical evidence.

Gain valuable evidence-based recommendations on key topics such as acute organ failure, infection, sepsis and inflammation, and prevention issues pointing the way to the most effective approaches.

Get an overview of each question, an outline of management options, a review of the relevant evidence, areas of uncertainty, existing management guidelines, and authors’ recommendations.

Navigate a full range of challenges from routine care to complicated and special situations.

Find the information you need quickly with tables that summarize the available literature and recommended clinical approaches.

Stay current on the latest advances in the field with full-text, online access that includes regular updates to emerging clinical evidence






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