Unmet healthcare needs of young populations and individuals in suboptimal health conditions are the key issue of currently observed epidemics of non-communicable disorders. Moreover, an unprecedented decrease in the average age of onset of these disorders is recorded. The majority of non-communicable disorders carry a chronic character by progressing over a couple of years from a reversible suboptimal health condition to irreversible pathology with collateral complications. The time-frame between both conditions is the operational area for predictive diagnosis and identification of persons at risk by innovative screening programmes followed by the most cost-effective personalised treatment possible, namely primary prevention tailored to the person.
The book propagates the paradigm change from delayed, costly but frequently ineffective medical services to the holistic approach by predictive, preventive and personalised medicine clearly demonstrating multifaceted benefits to the individual, healthcare sector and society as a whole.
The book is focused on the needs of
young people: teenagers, adolescents and young adults;
regardless of the age, individuals in suboptimal health conditions, who are interested in remaining healthy by optimising their modifiable risk factors – both endogenous and exogenous ones;
several patient cohorts demonstrating similar phenotype of Flammer syndrome.
The book is based on the multi-professional expertise, scientific excellence and practical experiences of the world-acknowledged experts in Flammer syndrome, predictive diagnostics, targeted prevention and personalised medicine, amongst others. The topic of this book is particularly relevant to general practitioners, experts in non-communicable diseases, phenotyping, genotyping, multilevel diagnostics, targeted prevention, personalised medicine, as well as the readers interested in advancing their health literacy.
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This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.
Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.
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This book represents the definitive robotic thoracic surgery atlas, containing didactic material necessary to facilitate effective practice in thoracic surgery and to provide learning tools in these methods both to practicing surgeons and to those in training. It defines the complete operative pathway for each procedure for surgeons who wish to be a complete robotic cardiothoracic surgeon and includes hints and procedural pitfalls derived from the experiences of chapter contributors.
The Atlas of Robotic Thoracic Surgery is illustrated with high quality illustrations and color photographs from surgical operations and contains expert analysis from leading surgeons who provide the key visual features of their chosen topics. Anesthetic and cardiopulmonary support preparation for each operation are included and selected references are provided to emphasize evidence-based outcomes.This book has been designed to augment Atlas of Robotic Cardiac Surgery edited by Ranny Chitwood, both being developed from these same concepts of simplicity and practical instruction. It will therefore be an important resource for all involved in thoracic robotic surgery or interested in learning more about the techniques involved.
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This book provides a concise and practical overview of hospital based emergency, urgent and primary care service in Ophthalmology. Specialist consultants who wish to broaden their knowledge of the various ophthalmic conditions seen in clinical emergencies will find this book to be a useful go-to guide. Advice is given on establishing an ophthalmic emergency and primary care service and a series of chapters cover the management of emergency eye conditions.
Emergency, Acute and Rapid Access Ophthalmology is a must read for all ophthalmic professionals in the UK and worldwide who are dealing with the growing demand for emergency eye care services and the increasing sub-specialisation within Ophthalmology.
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Beginning with a brief history of the subject, the following chapters cover all aspects of immunology, from basic immunity and antigens, to immunodeficiency disorders including HIV, tumour immunology, and transplantation immunology.
This concise second edition is highly illustrated with detailed graphics, colour diagrams, charts and tables, and each chapter features study questions and suggestions for further reading.
Fully revised, second edition, providing latest information on complete field of immunology
Highly illustrated with graphics, diagrams, charts and tables
Study questions and further reading suggestions included in each chapter
Previous edition published in 2007