MicroRNA : Perspectives in Health and Diseases

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Jan 182018

This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful.

The present volume is unique in that it documents some of the latest research in this area in Indian labs. The first chapter describes the basic biology of miRNA biogenesis, to bring into perspective the known mechanisms for miRNA generation. The second chapter deals with computational methods to predict miRNA genes and their target genes, and to understand the mechanism of miRNA function by theoretical modeling of gene regulatory networks. The subsequent chapters discuss the involvement of miRNAs in a variety of human diseases and disease processes, including glioblastoma, neurogenesis and neurodegeneration, multiple sclerosis, inflammatory bowel disease, parasitic infections, hepatocellular carcinoma, Alzheimer’s disease, and metabolic disorders. The authors highlight the miRNA-based therapeutic strategies, and the use of miRNAs as biomarkers for monitoring disease progression. Pathogens can exploit host miRNAs, as well as express their own miRNAs to promote their survival and evade host immune response. In other diseases, the expression of different miRNA classes is associated with disease progression and can be used for early detection and prognosis. The replacement or inhibition of miRNAs could also be used for potential therapy. Obviously, the pattern of expression of disease-related miRNAs could be specific to different ethnic populations, which makes the studies with Indian patients essential and important. This volume will be invaluable to students, researchers, and clinicians and would hopefully boost further research with miRNAs to harvest the potential of these molecules for the benefit of patients.



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Acute Myeloid Leukemia: Methods and Protocols

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Jan 172018



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Plant Medicines, Healing and Psychedelic Science: Cultural Perspectives

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Jan 132018

This is a book about the intersections of three dimensions. The first is the way social scientists and historians treat the history of psychiatry and healing, especially as it intersects with psychedelics. The second encompasses a reflection on the substances themselves and their effects on bodies. The third addresses traditional healing, as it circles back to our understanding of drugs and psychiatry. The chapters explore how these dimensions are distinct, but deeply intertwined, themes that offer important insights into contemporary healing practices.
The intended audience of the volume is large and diverse: neuroscientists, biologists, medical doctors, psychiatrists, psychologists; mental health professionals interested in the therapeutic application of psychedelic substances, or who work with substance abuse, depression, anxiety, and PTSD; patients and practitioners of complementary and alternative medicine; ethnobotanists and ethnopharmacologists; lawyers, criminologists, and other specialists in international law working on matters related to drug policy and human rights, as well as scholars of religious studies, anthropologists, sociologists, and historians; social scientists concerned both with the history of science, medicine, and technology, and concepts of health, illness, and healing. It has a potentially large international audience, especially considering the increasing interest in “psychedelic science” and the growing spread of the use of traditional psychoactives in the West.







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How to Make Disease Disappear

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Jan 132018

A much-needed program to prevent and reverse disease, and discover a path to sustainable, long-term health from an acclaimed international doctor and star of the BBC program Doctor in the House.

How to Make Disease Disappear is Dr. Rangan Chatterjee’s revolutionary, yet simple guide to better health—a much-needed, accessible plan that will help you take back control of your health and your life.

A physician dedicated to finding the root cause of ill health rather than simply suppressing symptoms with drugs, Dr. Chatterjee passionately advocates and follows a philosophy that lifestyle and nutrition are first-line medicine and the cornerstone of good health. Drawing on cutting edge research and his own experiences as a doctor, he argues that the secret to preventing disease and achieving wellness revolves around four critical pillars: food, relaxation, sleep, and movement. By making small, incremental changes in each of these key areas, you can create and maintain good health—and alleviate and prevent illness. As Dr. Chatterjee, reveals we can reverse and make disease disappear without a complete overhaul of our lifestyle.

His dynamic, user-friendly approach is not about excelling at any one pillar. What matters is balance in every area of your life, which includes:

• Me-time every day
• An electronic-free Sabbath once a week
• Retraining your taste buds
• Daily micro-fasts
• Movement snacking
• A bedtime routine

Practical and life-changing, How to Make Disease Disappear is an inspiring and easy-to-follow guide to better health and happiness.





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Graceful Exit: How to Advocate Effectively, Take Care of Yourself, and Be Present for the Death of a Loved One

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Jan 122018

When we are thrust into the role of caregiver for a loved one who is in the process of dying, it’s easy to get overwhelmed. Yet it’s a situation millions of us face every year with virtually no sort of preparation or guidance. With Graceful Exit, Dr. Gustavo Ferrer offers an all-in-one resource for anyone tasked with managing the end-of-life care of a loved one.

Dr. Ferrer shares the essential steps we need to take in a way that can be tailored to our unique situation. Through checklists, plans, and step-by-step instructions reflecting his years of experience supporting patients and their families, Dr. Ferrer offers clear and compassionate guidance for the most difficult issues, including:

• What are your rights under Medicare and health insurance?
• When should you bring your family together?
• How can you be a caregiver without burning yourself out?
• What are the pros and cons of advanced medical treatment versus hospice at each end-of-life stage?
• Most importantly, how do we say goodbye in a way that brings healing, closure, and peace?

It’s the last news we want to hear—that someone we love is dying. Yet it’s an inevitable part of life. With Graceful Exit, Dr. Ferrer offers this much-needed guide through the medical, legal, financial, emotional, and spiritual dimensions of dying and death.





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Ending the Search: From Spiritual Ambition to the Heart of Awareness

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Jan 122018

Do you ever feel as if your spiritual search is getting you nowhere? That despite sincere intention and effort, you’re reaping frustration instead of fruit? In Ending the Search, Dorothy Hunt unravels a dilemma that has vexed countless people on a spiritual path. “You may have tried all manner of practices, meditation, guru shopping, chanting, prayer, and still you have not attained your heart’s desire,” she writes. “This book is about the ego’s spiritual ambition, its search for its idea of ‘enlightenment,’ its struggles and its eventual fate as seeker becomes the sought.”

Ending the Search explores the deep spiritual impulse to awaken and the ways a future-focused mind “co-opts” or veils what is timelessly free, loving, and ever present. Dorothy invites us to follow our longing for truth, love, or enlightenment back to their source—the Heart that is beckoning us beyond separation. While describing and honoring different practices and paths taken in one’s search for Truth, she emphasizes the practice of self-inquiry as taught by Ramana Maharshi. We are invited to search not for an idea of something “out there,” but for the true identity of the seeker, the unnamable Mystery that is compassionately aware, existing right now in each of us. The book also looks at the processes of embodiment and surrender, the need for “ruthless honesty” without self-judgment, and in its concluding section, shares a vision of life lived authentically.

“The spiritual search is a call to remember who or what you essentially are,” explains Dorothy Hunt. “What ends the search is actually present from the very beginning, beckoning you to come Home. In truth, you are what you seek, yet you must make the discovery for yourself.” This is your invitation, with Ending the Search.





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Theory and Applications of Heat Transfer in Humans

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Jan 122018

Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author a noted expert in the field presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain decent estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named Physics , presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named Physiology , presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named Applications , presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow.

This important text is the vital resource that:

Offers a reference book in the field of heating and cooling of tissue, and associated damage.
Provides a comprehensive theoretical and experimental basis with biomedical applications
Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures
Includes simple examples and results so readers can use those results directly or adapt them for their applications
Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.





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Health Inequities in India: A Synthesis of Recent Evidence

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Jan 112018




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Phycobiliproteins: Recent Developments and Future Applications

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Jan 102018




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Practical Veterinary Dental Radiography

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Jan 092018

With over 1,000 clear, high-quality images, this in-depth full guide covers all aspects of veterinary dental radiography. Chapters explain the indications for – and importance of – this key area of veterinary practice, the equipment used, the essential techniques in developing and processing the radiograph, common errors made, and the pathology of the teeth. The book also explores radiographic interpretation in seven detailed sections, discussing all aspects from normal radiographic anatomy to endodontic disease and trauma. An additional chapter covers techniques and interpretation with exotics in three sections: rabbits, ferrets and rodents. The book concludes with a look at future directions in this field.

Essential reading for all veterinary practitioners, this book is also the ideal guide for trainees.






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 Posted by at 5:10 pm