Noted experts review the current status of boron-containing drugs and materials for molecular medical diagnostics
Boron-Based Compounds offers a summary of the present status and promotes the further development of new boron-containing drugs and advanced materials, mostly boron clusters, for molecular medical diagnostics. The knowledge accumulated during the past decades on the chemistry and biology of bioorganic and organometallic boron compounds laid the foundation for the emergence of a new area of study and application of boron compounds as lipophilic pharmacophores and modulators of biologically active molecules.This important text brings together in one comprehensive volume contributions from renowned experts in the field of medicinal chemistry of boron compounds.
The authors cover a range of the most relevant topics including boron compounds as modulators of the bioactivity of biomolecules, boron clusters as pharmacophores or for drug delivery, boron compounds for boron neutron capture therapy (BNCT) and for diagnostics, as well as in silico molecular modeling of boron- and carborane-containing compounds in drug design. Authoritative and accessible, Boron-Based Compounds:
Contains contributions from a panel of internationally renowned experts in the field
Offers a concise summary of the current status of boron-containing drugs and materials used for molecular diagnostics
Highlights the range and capacity of boron-based compounds in medical applications
Includes information on boron neutron capture therapy and diagnostics
Designed for academic and industrial scientists, this important resource offers the cutting-edge information needed to understand the current state of boron-containing drugs and materials for molecular medical diagnostics
About the Author
Prof. Dr. Evamarie Hey-Hawkins has been a Full Professor of Inorganic Chemistry at Leipzig University since 1993. Her research interests include the synthesis of novel reagents for BNCT and use of boron clusters as pharmacophores or modulators for biomolecules.
Prof. Dr. Clara Viñas Teixidor is a Research Professor at the Institut de Ciència de Materials de Barcelona, Spanish Council for Scientific Research, Spain. Her fields of research involve synthesis and derivatisation of boron clusters to be applied in medicine and biosensing, among others. Previously, she worked in industry and at public institutions involved in food science analysis as well as environmental control.
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