Nov 222016
 

Telocytes: Connecting Cells (Advances in Experimental Medicine and Biology)


This book elucidates the genetic, biological, morphological and functional aspects of telocytes. Telocytes are a recently defined type of interstitial (stromal) cells, with very long (tens to hundreds of micrometres) and very thin prolongations (mostly below the resolving power of light microscopy). The book describes the presence of telocytes in various organs and tissues, details their morphological characteristics, explores their genomic and proteomic profiles, puts forward preclinical evidence of their application, and discusses their potential in the context of clinical therapeutics. As such, it offers a valuable guide for biologists and clinicians alike.

Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of the Shanghai Institute of Clinical Bioinformatics, Executive Director of the Clinical Science Institute at Fudan University Zhongshan Hospital, Shanghai, China; Dr. Dragos Cretoiu is an Associate Professor of Pathology at the Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest.

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Nov 222016
 

Safety of Biologics Therapy: Monoclonal Antibodies, Cytokines, Fusion Proteins, Hormones, Enzymes, Coagulation Proteins, Vaccines, Botulinum Toxins


By (author): Brian A. Baldo

This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters.  It is predicted that by 2016, biologics will make up half of the world’s 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world’s 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

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Nov 212016
 

Nonsurgical Lip and Eye Rejuvenation Techniques


This book offers clinical physicians and plastic surgeons a detailed and comprehensive overview of the nonsurgical techniques used for rejuvenation of the lips and eyes. A key aim is to provide practical guidelines for patient selection in order to optimize the choice of treatment in different circumstances. These guidelines will assist in ensuring that the selected rejuvenation technique and the number of applications are appropriate to the specific disorder being treated, thereby maximizing benefits and minimizing side effects.

The book explains pretreatment evaluation and describes a wide variety of rejuvenation techniques, including the use of hyaluronic acid fillers, botulinum toxins, skin needling, chemical peels, radiofrequency, ultrasound, and fractional lasers (ablative and nonablative). Contraindications to and complications of the various treatments are clearly identified. A notable feature is the emphasis placed on the role of combined treatments and how they can work in a complementary way to deliver optimal outcomes. The integrated, less invasive approach to periorbital and lip rejuvenation described here by acknowledged experts in the field will enable practitioners to choose with confidence the best aesthetic procedures and innovative tools for their patients.

List Price: $129.00 USD
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Nov 202016
 

Stem Cell Transplantation: Biology, Processes, Therapy


Features: Used Book in Good Condition

This is the first handbook on the whole field of stem cell research covering (1) molecular and cellular fundamentals, (2) clinical applications and (3) GMP processing. It provides a timely overview of the potential and plasticity of adult stem cells. With its focus on standardization and quality control of cell lines suited for processing and clinical trials, the book features novel therapeutic approaches that offer great promise for new ways of treating neural, hematological and cardiovascular diseases.
The editors are leading international experts in adult stem cell research, and their successful networking in the US and Europe has resulted in a distinguished team of authors from around the world.
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Nov 202016
 

Stem Cell Transplantation (Advances in Experimental Medicine and Biology, Vol. 741)


Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields?areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.
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Nov 202016
 

Coverage Matters: Insurance and Health Care


By (author): Committee on the Consequences of Uninsurance, Board on Health Care Services, Institute of Medicine, Institute of Medicine

Roughly 40 million Americans have no health insurance, private or public, and the number has grown steadily over the past 25 years. Who are these children, women, and men, and why do they lack coverage for essential health care services? How does the system of insurance coverage in the U.S. operate, and where does it fail? The first of six Institute of Medicine reports that will examine in detail the consequences of having a large uninsured population, Coverage Matters: Insurance and Health Care, explores the myths and realities of who is uninsured, identifies social, economic, and policy factors that contribute to the situation, and describes the likelihood faced by members of various population groups of being uninsured. It serves as a guide to a broad range of issues related to the lack of insurance coverage in America and provides background data of use to policy makers and health services researchers.

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Nov 202016
 

The Encyclopedia of the Back and Spine Systems and Disorders (Facts on File Library of Health & Living)


Features: Used Book in Good Condition
By (author): Mary Harwell Sayler

Back pain is the most common cause of job-related disability. This is a reference to these parts of the body and the ailments of sufferers. It provides information on various aspects of the back and spine, including anatomy, metabolic processes, neurological systems, injuries, diseases and disorders, treatments, medicines, and nutrition.
List Price: $75.00 USD
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Nov 192016
 

The Social Value of Drug Addicts: Uses of the Useless


By (author): Merrill Singer, J Bryan Page

Drug users are typically portrayed as worthless slackers, burdens on society, and just plain useless?culturally, morally, and economically. By contrast, this book argues that the social construction of some people as useless is in fact extremely useful to other people. Leading medical anthropologists Merrill Singer and J. Bryan Page analyze media representations, drug policy, and underlying social structures to show what industries and social sectors benefit from the criminalization, demonization, and even popular glamorization of addicts. Synthesizing a broad range of key literature and advancing innovative arguments about the social construction of drug users and their role in contemporary society, this book is an important contribution to public health, medical anthropology, popular culture, and related fields.
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Nov 182016
 

The 10-Minute Clinical Assessment


By (author): Knut Schroeder

Clinical assessment is at the heart of medicine. Health professionals working in busy clinical settings, such as general practitioners, nurse practitioners and hospital doctors on-call, often have to assess patients under considerable time constraints. This book teaches the reader how to gather clinical information effectively, accurately and safely even when time is at a premium.

  • Provides a systematic method of collecting and assessing relevant clinical information by suggesting step-by-step examination routines, including important patient-centred questions
  • Focuses on common symptoms and presentations
  • Treatment reflects the latest in evidence based practice (including latest NICE Guidelines)
  • Specifically covers the clinical skills assessment (CSA) part of the Membership of the Royal College of General Practitioners (RCGP) examination
  • Written by an experienced medical educator and practicing GP, in consultation with a multidisciplinary team of medical students, GPs, PG trainees, hospital doctors and nurses
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Nov 182016
 

Endothelial Cell Biology in Health and Disease


Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated. Beginning with the middle of the 19th cen­ tury, our knowledge of the histological organization of blood vessels has steadily increased. However, the endothelium, which for a long time was considered to be just an inert barrier lining, had been barely explored until three decades ago. Since then, there has been an upsurge of interest in the fine structure and function of endothelial cells. Intense in vivo and in vitro investigations have revealed that the endothelial cell is a key element in a wide variety of normal activities and diseases. A large number of investigators and laboratories have been attracted to endothelial cell research, thus supporting the expansion of the continuously grow­ ing and diversifying field of endotheliology. The number of articles published annually on this subject has increased from a few score at the beginning of the 1970s to more than a thousand in recent years, and an increasing number of journals, books, societies, and symposia focused primarily on the vascular en­ dothelium have marked the last decade.
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