Extracellular RNA

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Feb 112018
 

This volume provides a collection of methods and protocols detailing extracellular RNA and hopes to be a useful resource for those interested in this exciting and emerging field. Chapters are divided into four sections covering an overview of the field, approaches for the isolation of exRNA, protocols for detection and quantitation of exRNA, and approaches that can be useful for studies to evaluate potential therapeutic applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Extracellular RNA: Methods and Protocols aims to ensure successful results in the further study of this vital field.

 

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http://nitroflare.com/view/F94C8D8CE3DB08F/1493976516.epub

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Guide to Evidence-Based Physical Therapist Practice, Fourth Edition

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Feb 102018
 

Guide to Evidence-Based Physical Therapist Practice, Fourth Edition teaches the knowledge and skills to evaluate medical evidence and apply it to the practice of physical therapy. This valuable reference explains the fundamentals of medical research and how to determine which studies are useful in practice. As the leading evidence-based practice text for physical therapy, this is a comprehensive resource no physical therapist or student should be without.

The Fourth Edition has been updated with new clinical scenarios, additional research examples, and more activities to support the application of key concepts. This practical guide empowers readers to learn how to evaluate research designs, appraise evidence, and apply research in clinical practice. Its reader-friendly style facilitates learning and presents the knowledge essential for physical therapist students to develop a strong foundation in research methods and methodologies related to evidence-based medicine.

New to the Fourth Edition
• New Clinical Scenarios at the beginning of each chapter aid in the application of key concepts
• New chapter on appraising qualitative research studies
• Expanded coverage of clinical practice guidelines
• Updated coverage of the most commonly used electronic search engines
• Inclusion of updated terminology from the APTA’s Guide to Physical Therapist Practice 3.0

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http://nitroflare.com/view/930AE54437F3C91/Guide_to_Evidence-Based_Physical_Therapist_Practice.pdf

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Human Dna Polymerases

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Feb 102018
 

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes.

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http://nitroflare.com/view/493E038F79A11F5/Human_Dna_Polymerases_Biology%2C_Medicine_And_Biotechnology.pdf

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Biopsychology, Global Edition

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Feb 102018
 

For courses in Physiological Psychology and Biopsychology

Explore how the central nervous system governs behavior
Biopsychology presents a clear, engaging introduction to biopsychological theory and research through a unique combination of biopsychological science and personal, reader-oriented discourse. Original author John Pinel and new co-author Steven Barnes address students directly and interweave the fundamentals of the field with clinical case studies, useful metaphors, and memorable anecdotes that make course material personally and socially relevant to readers. In addition to expanded learning objectives that guide students through the course, the Tenth Edition has been thoroughly updated to reflect this rapidly progressing scientific field.

Available to package with Biosychology, Tenth Edition, MyLab™ Psychology is an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. MyLab Psychology is ideal for courses requiring robust assessments.

Biosychology, Tenth Edition is also available via Revel™, an interactive digital learning environment that replaces the print textbook, enabling students to read, practice, and study in one continuous experience. Revel is ideal for courses where student engagement and mobile access are important.

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http://nitroflare.com/view/BB77F01F7DBDF8F/Biopsychology%2C_Global_Edition.pdf

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The Chronic Ear

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Feb 082018
 

There is excellent coverage of a wide range of the surgical techniques employed in tympanoplasty, cholesteatoma removal, cavity design and reconstruction….I wish I had seen this book 20 years ago. The book is as valuable to the expert as to the neophyte trainee. – The Journal of Laryngology & Otology

The unique ’roundtable’ format permits juxtaposition of different techniques for the same problem which provides the reader with ample opportunity to compare the pros and cons of the different strategies…. should be required reading for residents and fellows. – Otology & Neurotology

There are many different ways to treat complex chronic middle ear disease, with ongoing advancements being made globally. Diverse approaches are necessitated for variations in patient age, degree of infection, extent of middle ear remodeling, inflammation severity, and underlying mechanisms of Eustachian tube dysfunction. Addressing multinational and clinical nuances, the editors have compiled 48 chapters with eclectic perspectives from otology experts in 13 countries.

The surgical anatomy of the middle ear cleft and mastoid and underlying pathophysiological mechanisms of chronic otitis media are clinically challenging. Articles cover anatomy, physiology, disease characterizations and manifestations, clinical evaluation, office management, surgical procedures, and new horizons. Traditional and newer hybrid techniques for systematic disease and inflammatory conditions are presented in roundtable format, for example, underlay fascia tympanoplasty as well as the use of cartilage and bioengineered materials.

Selected Key Topics:

Applied middle ear anatomy and physiology
Pathologic mechanisms of chronic otitis media
Office evaluation, management and surgical decision making
Mastoid cavity obliteration and canal wall reconstruction
Challenges in tympanoplasty and ossicular chain reconstruction
Traditional and hybrid tympanomastoid surgery
Hearing implants in the chronic ear
This is an exceptional teaching tool for ear surgeons in training as well as a must-have clinical resource for practicing otolaryngologists.

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http://nitroflare.com/view/A250721CBED38C4/The_Chronic_Ear.pdf

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IgM and Its Receptors and Binding Proteins

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Feb 082018
 

This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fcα/µR), and Fc receptor for IgM only (FcµR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcµR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike.
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Managing a Modern Hospital

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Feb 082018
 

 

The revised and updated second edition of Managing a Modern Hospital contains a judiciously compiled collection of writings on modern hospital management. The book is a fitting response to the compelling need for incorporating professionalism and better resource management in hospital administration to ensure quality and cost-effectiveness in health care in India.

Health care has become one of the fastest growing sectors in India over the past decade. This book contains two new chapters, Customer Relationship Management, and Computer-aided Diagnosis, which highlight recent developments in the field in the last seven years. It spans a wide range of issues in modern hospital management, including:
– Waste management
– Financial management
– Maintaining medical records
– Medical audits
– Managing human resources
– Quality certification

A repository of valuable insight and information on setting up and running a modern-day hospital efficiently and as an economically viable business, the book can serve as basic text and supplementary reading for courses in hospital management. It will also be of interest to hospital administrators in government and private health care institutions, directors of nursing homes, medical practitioners involved with hospital administration as well as entrepreneurs in the health care business, consultants and researchers.

 

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http://nitroflare.com/view/1602C95DB9B48AC/Managing_a_Modern_Hospital.pdf

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Management of Atopic Dermatitis: Methods and Challenges

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Feb 082018
 

This book is designed to provide a foundation of knowledge regarding the epidemiology, pathogenesis, and clinical presentation of atopic dermatitis in both pediatric and adult patients. It provides an overview of the mechanism and presentation of atopic dermatitis and focuses on the management methods experienced dermatologists have used to successfully manage atopic dermatitis. This book provides physicians with insights into the management of atopic dermatitis, such as alternative treatments for pruritus, psychosocial impact on patients and families, assessing patient compliance, and patient resources.

This book also:
– Provides proven strategies for treating atopic dermatitis
– Helps providers create a treatment plan for their atopic patients
– Aids physicians in developing techniques for assessing patient compliance
– Thoroughly addresses the significant economic and psychosocial impact of atopic dermatitis

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http://nitroflare.com/view/E203FFFA3CEC4AF/3319648039.pdf

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Patch-Based Techniques in Medical Imaging: Third International Workshop

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Feb 082018
 

 

This book constitutes the refereed proceedings of the Third International Workshop on Patch-Based Techniques in Medical Images, Patch-MI 2017, which was held in conjunction with MICCAI 2017, in Quebec City, QC, Canada, in September 2017.
The 18 regular papers presented in this volume were carefully reviewed and selected from 26 submissions. The papers are organized in topical sections on multi-atlas segmentation; segmentation; Alzheimer’s disease; reconstruction, denoising, super-resolution; tumor, lesion; and classification, retrival.

 

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Fiber-based Optical Trapping and Manipulation

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Feb 062018
 

 

Since its first report in 1970 by A. Ashkin, optical trapping and manipulation has been widely used in the interdisciplines of micro- and nano-photonics, biophotonics, biomedicine, etc. A conventional tool for optical trapping and manipulation is the conventional optical tweezer (COT), the core part of which is a free-space focused laser beam. However, manipulation with COTs has some limitations such as manipulation inflexibility, bulky structure, diffraction limitation for nanoparticles, and limited integration functions. The introduction of optical fiber-based optical trapping and manipulation has solved these limitations. Using optical fibers with different configurations, optical trapping and manipulation with multiple functions can be realized with high flexibility, precision, and integration. By launching laser beams with different wavelengths into the fiber, both the photothermal effect and optical force can be used for optical trapping and manipulation. For the optical force manipulation, both evanescent fields at the surface of a subwavelength optical fiber and light output from a fiber end can be used for optical manipulation. The manipulation with light output from a fiber end can be divided into dual fiber tweezers and single fiber tweezers. For single fiber tweezers, one can realize the stable trapping of single particles both in a contact and non-contact manner for further applications. In addition, single fiber tweezers can also be used for multiple particle trapping and cell assembly, which can further be used for the assembly of biophotonic components and devices. Furthermore, by placing microparticles, which act as microlens at the end facet of an optical fiber, the microlens can be served as a photonic nanojet. This fiber supported photonic nanojet can be easily used for the trapping and detection of nanoparticles and biomolecules. Optical fiber-based optical trapping and manipulation have the advantages of easy fabrication, compact configuration, flexible manipulation, easy integration, wide applicability, etc., which provides for a wide application of prospects in micro- and nano-photonics, biophotonics, and biomedicine

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