Nov 182017
 

Caring for Quality in Health: Lessons Learnt from 15 Reviews of Health Care Quality: Edition 2016 (OECD Reviews of Health Care Quality) (Volume 2016)


By (author): Oecd Organisation For Economic Co-Operation And Development

Over the past four years, the Oecd has conducted a series of in-depth reviews of the policies and institutions that underpin the measurement and improvement of health care quality in 15 different health systems. This synthesis report draws on key lessons from the Oecd Health Care Quality Review series. The objective is to summarise the main challenges and good practices to support improvements in health care quality, and to help ensure that the substantial resources devoted to health are being used effectively in supporting people to live healthier lives. The overarching conclusion emerging across the Health Care Quality Review series concerns transparency. Governments should encourage, and where appropriate require, health systems and health care providers to be open about the effectiveness, safety and patient-centredness of care they provide. More measures of patient outcomes are needed (especially those reported by patients themselves), and these should underpin standards, guidelines, incentives and innovations in service delivery. Greater transparency can lead to optimisation of both quality and efficiency – twin objectives which reinforce, rather than subvert, each other. In practical terms, greater transparency and better performance can be supported by changes in where and how care is delivered; changes in the roles of patients and professionals; and employing tools such as data and incentives more effectively. Key actions in these three areas are set out in the twelve lessons presented in this synthesis report.

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Nov 182017
 

New Health Technologies: Managing Access, Value and Sustainability


By (author): Oecd Organisation For Economic Co-Operation And Development

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Nov 172017
 

Phospholipases in Health and Disease (Advances in Biochemistry in Health and Disease)


Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions. While several physiological, biochemical and molecular techniques have identified key players involved in different disease processes, phospholipases have also emerged as critical players in the pathogenesis of a number of different diseases including cancer and heart disease. In addition, phospholipases are also implicated in such conditions as brain disorder/injury, kidney and immune cell dysfunction.

Phospholipases in Health and Disease is a compilation of review articles dedicated to the study of the field with respect to biochemical and molecular mechanisms of normal and abnormal cell function. The wide range of area covered here is of interest to basic research scientists, clinicians and graduate students, who are engaged in studying pathophysiological basis of a variety of diseases. Furthermore, this book highlights the potential of the different phospholipases as therapeutic targets as well as part of prevention strategies. Twenty three articles in this book are organized in four sections that are designed to emphasize the most characterized forms of the phospholipases in mammalian cells. The first section discusses general aspect of phospholipases. Section two covers the role and function of phospholipase A in different pathophysiological conditions. The third section is focussed on phospholipase C which is believed to play a central role in transmembrane signaling. The final section covers phospholipase D which is present in a variety of different cells. The book illustrates that the activation of phospholipases is of fundamental importance in signal transduction affecting cell function. Overall, this book discusses the diverse mechanisms of phospholipase mediated signal transduction in different pathophysiological conditions and raises the possibility of specific forms of phospholipases serving as novel targets for drug development.

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Nov 172017
 

Sensory Organ Replacement and Repair (Synthesis Lectures on Biomedical Engineering)


By (author): Gerald Miller

The senses of human hearing and sight are often taken for granted by many individuals until they are lost or adversely affected. Millions of individuals suffer from partial or total hearing loss and millions of others have impaired vision. The technologies associated with augmenting these two human senses range from simple hearing aids to complex cochlear implants, and from (now commonplace) intraocular lenses to complex artificial corneas. The areas of human hearing and human sight will be described in detail with the associated array of technologies also described.
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Nov 172017
 

Coronary Imaging and Physiology


This book is intended as a guide for all cardiologists who are interested in coronary imaging and physiology, a sound understanding of which is vital for the optimal performance of appropriate coronary interventions. The basics of each relevant modality are presented, with clear explanation of clinical utility and evaluation of the evidence regarding clinical outcomes. All technical methods are described in detail, and the text is complemented by numerous helpful tables and illustrations.
The effectiveness of intravascular coronary imaging in improving clinical outcomes is proven, and it is widely used for this purpose. Two modalities for intravascular coronary imaging are available in clinical practice: intravascular ultrasound (IVUS) and optical coherence tomography (OCT). For coronary physiology, the pressure wire-derived fractional flow reserve (FFR) provides information on the functional status of coronary trees. This technique and its clinical applications receive particular attention in the book, which also looks beyond FFR to FFR-CT, a method using computational fluid dynamics, and to invasive assessment of the microcirculation. 
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Nov 172017
 

The Beauty of Discomfort: How What We Avoid Is What We Need


By (author): Amanda Lang

Why do some people drive change while others are blindsided by it?

Why are some people able to adapt and thrive?

How can we make change easier?

Truly successful people don’t merely tolerate discomfort—they embrace it and seek it out again and again. Business founders and university students, top athletes and couch potatoes, meditation gurus and military leaders all have very different ways of coping with discomfort, but the most successful among them believe that withstanding discomfort is a skill that has helped them in hugely positive ways. Some were forced into discomfort through no choice of their own—a life-altering illness, a business fiasco—while others signed up for it because they had goals they were determined to achieve.

Some degree of discomfort is inherently good for you. It can spur you on, pushing you to test your own limits. Learning to tolerate, and then embrace, discomfort is the foundation for change, for individuals and businesses alike. Becoming comfortable with discomfort won’t just make us more resilient and more successful, however we define success. It will also make us happier.

 

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Nov 172017
 

Gene and Cell Therapies for Beta-Globinopathies (Advances in Experimental Medicine and Biology)


Hemoglobin defects, specifically sickle cell disease & thalassemia, combined, constitute the most common monogenic disorders in the world. In fact, nearly 2% of the world’s population carries a globin gene mutation. The transfer of the corrective globin gene through the HSC compartment by allogeneic HSC transplantation (HSCT) has already proven curative in both SCD and thalassemia patients, and provides the proof of concept that genetic manipulation of the defective organ might be equally therapeutic. However, procedural toxicities and the requirement of an HLA-matched sibling donor limit this approach to a fraction of affected individuals. The editors review the progress & the state of the field in HSCT for hemoglobinopathies & shed light on the major changes expected in the next decade. Although allogeneic HSCT is a curative option, it is limited by the availability of matched donors, which are often available only to 15-20% of patients. An alternative to allogeneic HS

CT is genetic correction of autologous HSCs, to overcome donor availability & immune side effects. This Book reviews the progress made on additive gene therapy approaches & the current state of the field. Finally, targeted genetic correction is emerging as a novel therapeutic strategy in the hemoglobinopathies. Although ideal, the inefficiency of targeted correction was rate limiting for translation of this technology to the clinic. With advancements in zinc finger nucleases and TALE endonuclease mediated targeted correction, correction frequencies in hematopoietic stem cells is now reaching levels that may become clinically relevant. Furthermore, the ability to generate autologous embryonic stem cell like cells from primary somatic cells (skin fibroblasts or hematopoietic cells) of the affected individual has allowed for the potential application of genetic correction strategies.This Book reviews upcoming genetic strategies to reactivate fetal hemoglobin production and research advances.

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Nov 172017
 

Ultraviolet Light in Human Health, Diseases and Environment (Advances in Experimental Medicine and Biology)


This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV dosimeter.

The book starts with introduction to UV light and the history of development of UV lamps and its applications. It then moves to describing the interaction of this light with biological components and the production of reactive oxygen species, their roles in cell signaling, cellular defense from foreign invaders, in mutagenesis leading to skin diseases including vitiligo, polymorphous light eruption and various forms of skin cancer. Then it presents the synthesis and importance of UV light and diseases, induced due to the deficiency of vitamin D. Roles of UV light in sterilization, disinfection, phototherapies are depicted in the next part and finally use and abuse of UV light in tanning salon and the availability and importance of use of UV dosimeter are highlighted.

The three main focuses of this book are:
– Damage to biological systems by UV light leading to certain skin diseases; most importantly skin cancers.
– Importance of UV light in the in vivo synthesis of vitamin D when human bodies are exposed to it.
– Diseases caused due to the deficiency of vitamin D and the use of UV lamps in phototherapy and sterilization processes.

The editor has considerable experience in publishing medical books and has used it critically selecting the matters which will attract the readers from many areas of medical and non-medical fields.

It is hoped that the materials presented in this book will give great benefit and will stimulate both novice and expert researchers in the field. The book gives excellent overviews of the current status of research and pointers to the future research achievements. Clinicians, medical general practitioners, technicians and staff working in UV related industries and especially those working in tanning salon should benefit from the information presented in safe handling of this light.

 

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Nov 172017
 

Writing a Proposal for Your Dissertation: Guidelines and Examples


Features: Taylor & Francis
By (author): Steven R. Terrell

This user-friendly guide helps students get started on–and complete–a successful doctoral dissertation proposal by accessibly explaining the process and breaking it down into manageable steps. Steven R. Terrell demonstrates how to write each chapter of the proposal, including the problem statement, purpose statement, and research questions and hypotheses; literature review; and detailed plan for data collection and analysis. Of special utility, end-of-chapter exercises serve as building blocks for developing a full draft of an original proposal. Numerous case study examples are drawn from across the social, behavioral, and health science disciplines. Appendices present an exemplary proposal written three ways to encompass quantitative, qualitative, and mixed-methods designs.

User-Friendly Features
*”Let’s Start Writing” exercises leading up to a complete proposal draft.
*”Do You Understand?” checklists of key terms plus an end-of-book glossary.
*End-of-chapter quizzes with answers.
*Case study examples from education, psychology, health sciences, business, and information systems.
*Sample proposal with three variants of the methods chapter: quantitative, qualitative, and mixed methods.
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Nov 172017
 

Handbook of Medical Tourism Program Development: Developing Globally Integrated Health Systems


By (author): Maria K. Todd

Explaining how to develop a patient-centered medical tourism program, the Handbook of Medical Tourism Development is the ideal guide for any hospital, clinic, hotel, spa, or ancillary facility wishing to become a medical tourism provider. From high-cost surgery, transplants, diagnostics, and preventive wellness checkups, to medical and wellness spa retreats, patient follow up, and outcomes measurement, this book covers the gamut of related issues.

  • Details the elements necessary for a successful system
  • Addresses contracting issues likely to arise
  • Includes access to additional resources on the book’s website

Maria K. Todd prepares readers to build the medical tourism service line, integrate physicians and other service providers, develop a safe and effective quality and patient-centered infrastructure, document processes and workflows, determine pricing, evaluate reimbursement contracts, and measure outcomes. She offers useful nuts-and-bolts guidance on confidentiality, documentation, quality and safety, hospital accreditation schemes, revenue implications, and contracting. Sharing time-tested insights, the book will help readers avoid common pitfalls when working with U.S. and international health insurance companies, case managers, professional facilitators, and multinational employers.

Read a recent press release about the Handbook of Medical Tourism Program Development:

http://www.prlog.org/11757451-medical-tourism-expert-breaks-down-step-by-step-medical-tourism-program-development-for-providers.html

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