Growth Hormone Deficiency: Physiology and Clinical Management

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Apr 072018
 

Describes both the mechanism of human growth hormone (HGH) and the etiology, diagnosis and management of HGH deficiency
Discusses not only HGH but also its interaction with sex steroids, thyroid hormones and syndromes that cause or are associated with HGH deficiency
Covers diagnosis and management of both pediatric and adult HGH deficiency

Providing the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.

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Salvia Biotechnology

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Apr 072018
 


The genus Salvia represents nearly 1,000 species that are widely distributed around the world. It is the largest in the Lamiaceae family. Traditionally, infusions of Salvia species have been widely used to treat oral inflammation, throat and headaches, and digestive disturbances in various folklore- and ethno-medicine practices worldwide.
The antispasmodic, antiseptic and hypoglycemic effects of their extracts have been recognized by the ancient healers a long time ago before the development of modern medicine. With the advances in phytochemistry and pharmacology, terpenes, polyphenols and volatile compounds have been recognized as the source of bioactivity in Salvia extracts. Nowadays, because of their valuable pharmaceutical and nutraceutical properties, many Salvia species have been widely used as ingredients in food, pharmacy and cosmetic industries. The economic importance of Salvia plants continues to increase, following closely the growing interest to the concept for modern healthy lifestyle, based on prevention by consuming quality foods and nutraceutical supplements of natural origin.

However, the growing demand has led to overexploitation of natural habitats and in the last few years many wild growing Salvia species have shrunk or fallen under threat. Obviously, to deal with that problem and to prevent ecological crisis, there is an urgent need for alternative, renewable sources of Salvia biomass. Plant biotechnology can provide a wide range of tools for development of economically feasible continuous production of standardized valuable phytochemicals. Plant in vitro culture technology is a powerful method for continuous production of plant secondary metabolites under controlled conditions, recently adapted to various Salvia species. Salvia in vitro systems are harmless to natural plant populations and can be grown independently of environmental factors, geographical latitude, climatic change, and seasonal variations. Several bioactive metabolites from rare and endangered Salvia plants can be produced by employing different plant in vitro systems. However, the researches on development of large scale biotechnology, based on Salvia in vitro systems, are still in early stages and many points still have to be addressed before the commercialization to take place.

In this book we intend to summarize the recent achievements in research with Salvia in vitro systems as biological matrixes for the production of pharmaceutically important secondary metabolites. Further we invited leading experts to present their recent studies on phytochemistry, ethnobotanical and ethnophamacological aspects of genus Salvia. Safety and legal issues related to implementation of Salvia plants and in vitro cultures extracts in foods, cosmetics and pharmaceutical products will be discussed as well.

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Breast Disease: Management and Therapies, Second Edition

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Apr 062018
 

This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches.
Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget’s disease and phyllodes tumors, and a section on supportive and follow-up care.
By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

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Mechanisms and Management of Pain for the Physical Therapist, 2nd Edition

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Apr 042018
 

Comprehensive in scope and invaluable for both practitioners and students, Mechanisms and Management of Pain for the Physical Therapist, 2nd Edition, thoroughly covers the wide range of issues requiring the interdisciplinary management of pain. Joined by more than 20 international contributors, Dr. Kathleen Sluka provides a practical, evidence-based framework for understanding the basics of pain mechanisms and management. This highly regarded, updated text covers the basics of pain neurobiology and reviews evidence on the mechanisms of action of physical therapy treatments, as well as their clinical effectiveness in specific pain syndromes.

The second edition features:
Basic Concepts and Mechanisms – provides a clear infrastructure for the rest of the book.
Physical Therapy Pain Management – focuses attention on pain regardless of medical diagnosis, using evidence to support clinical decision making.
Interdisciplinary Pain Management – includes both medical management of pain and psychological approaches to pain.
Case Studies – discuss a series of pain syndromes using an evidence-based approach.

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Medical Terminology Express: A Short-Course Approach by Body System, 2nd Edition

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Apr 022018
 

Now in its 2nd edition, Medical Terminology Express adapts Barbara Gylys’s proven word-building techniques for the short-course. Organized by body system, this text shows the connection between anatomical structures and associated medial word roots.
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Healthy Body Connection: Unlocking Your Body’s Natural Connection to Sustainable Weight Loss and Optimal Health

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Apr 022018
 

Healthy Body Connection: Unlocking Your Body’s Natural Connection to Sustainable Weight Loss and Optimal Health clears up the doubt and confusion caused by the overabundance of conflicting health advice and information being circulated to the public through the news, television, and social media.

The book gives readers conclusive answers to their questions about achieving peak health, avoiding chronic disease, losing weight, and dodging the illnesses that they may be genetically predisposed to. This book is unique because it guides people through lifestyle strategies, and gives them a customizable nutritional plan to help them achieve complete health in mind, body, and spirit.

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The Perrin Technique

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Apr 012018
 

Are you suffering from M.E.? Are you caring for someone with M.E.? Does someone close to you have M.E.? Almost certainly it will have taken your doctor some time to arrive at the diagnosis of M.E. and once there you may have been offered little more than antidepressants to help with the condition. In the interim you may have tried many alternative options including changes in diet and lifestyle.These may have helped but if the root cause is left untreated you are unlikely to recover your full health. After many years of careful study coupled with practical hands-on experience, Dr Raymond Perrin has arrived at the firm conclusion that M.E. is a structural disorder with definite diagnosable physical signs. He has developed the Perrin Technique to help drain toxins away from the central nervous system and stimulate the healthy flow of lymphatic and cerebrospinal fluid – the secret of setting you on the path to recovery. In his ground-breaking book you will find exclusive coverage of: * The role of toxins in chronic fatigue syndrome/M.E. * The importance of body structure and posture in developing M.E. * The stages leading to M.E. * The physical signs of M.E * How osteopathy can help * The stages of treatment * Exercises and self-massage routines The Perrin Technique gives you the chance to take charge of your own structural health and rid yourself of years of toxin build-up.

 

 

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The Ultimate Guide to Passing Clinical Medicine Finals (MasterPass) 1st Edition

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Apr 012018
 

A well prepared student takes the initiative to create learning opportunities and propel themselves towards qualification; we find that the better prepared you are, the luckier you become. From the Preface The key to passing clinical finals is not a secret; adequate preparation and the ability to think logically and speak clearly are all hallmarks of a successful candidate. This unique guide gives final year students the knowledge and confidence required to pass their examinations with insiders’ tips on particular information and skills required to be a top candidate. It is ideal as both a revision aid in the weeks leading up to the examination, and as an aide-memoire the night before.

 

 

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Complementary and Alternative Medicine: Knowledge Production and Social Transformation

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Apr 012018
 

This book examines how complementary and alternative medicine (CAM) – as knowledge, philosophy and practice – is constituted by, and transformed through, broader social developments. Shifting the sociological focus away from CAM as a stable entity that elicits perceptions and experiences, chapters explore the forms that CAM takes in different settings, how global social transformations elicit varieties of CAM, and how CAM philosophies and practices are co-produced in the context of social change.
Through engagement with frameworks from Science and Technology Studies (STS), CAM is reconceptualised as a set of practices and knowledge-making processes, and opened up to new forms of analysis. Part 1 of the book explores how and why boundaries within CAM and between CAM and other health practices, are being constructed, challenged and changed. Part 2 asks how CAM as material practice is shaped by politics and regulation in a range of national settings. Part 3 examines how evidence is being produced and used in CAM research and practice. Including studies of CAM in Eastern and Western Europe, Asia, and North and South America, the volume will appeal to postgraduate students, researchers and health practitioners.

 

 

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PET Scan in Hodgkin Lymphoma: Role in Diagnosis, Prognosis, and Treatment

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Mar 312018
 

This book describes the various contributions of positron emission tomography (PET) to the management of Hodgkin lymphoma and considers key issues in its use. A full explanation of the value of PET in disease staging and restaging is followed by discussion of its role in guiding individualized, response-adapted therapy in both early and advanced disease based on assessment of treatment sensitivity. Further chapters explore in detail the current application of PET for determination of tumor metabolic volume and planning of involved field radiotherapy. The book concludes by discussing PET scan reporting in clinical practice and the rules that have now been formally set following a number of international workshops designed to develop standard reporting criteria based on expert agreement. The authors are leading authorities who adopt an interdisciplinary approach in covering the most important aspects of the use of PET in Hodgkin lymphoma in a readily understandable way. PET Scan in Hodgkin Lymphoma will be of value to oncologists, hematologists, medical physicists, radiotherapists, and nuclear medicine specialists.

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