Clinical Mechanics in the Gut

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Mar 102018
 

The gastrointestinal tract is a series of organs each with distinct mechanical functions. Each organ within the system brings food contents in the gut lumen to the site of absorption through separate mechanical functions. These mechanical functions are generated by a fine-tuned interaction between neuronal networks and active muscle layers. The passive components of the gastrointestinal wall such as the collagen-rich submucosa also play an important role in these mechanical actions. Clinical Mechanics in the Gut provides a thorough understanding of the anatomy and biomechanics of the physiological function and pathophysiology of the gastrointestinal tract. The book first gives an introduction to readers about the physical geometry of the gastrointestinal tract followed by a detailed explanation of biomechanical theory and its application to approximating and modeling gut mechanics. This is expanded further by detailed explanations of gut muscle and motor nerve functions in proceeding chapters. A biomechanical evaluation of disorders of regulatory mechanisms such as achalasia and Hirschsprung disease and disorders of effector mechanisms such as reflux disease, systemic sclerosis of the gastrointestinal tract and colonic diverticular disease are also included. Readers will, therefore, gain an understanding about clinical problems in gastroenterology from a bioengineering and modeling perspective. Clinical Mechanics in The Gut is a useful reference for gastroenterology researchers, biomedical engineers and systems biologists seeking to understand the physiology of the gut and applying this knowledge to surgical procedures, computer-based modeling systems and robotics.

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Likelihood-Free Methods for Cognitive Science

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Mar 102018
 

This book explains the foundation of approximate Bayesian computation (ABC), an approach to Bayesian inference that does not require the specification of a likelihood function. As a result, ABC can be used to estimate posterior distributions of parameters for simulation-based models. Simulation-based models are now very popular in cognitive science, as are Bayesian methods for performing parameter inference. As such, the recent developments of likelihood-free techniques are an important advancement for the field.
Chapters discuss the philosophy of Bayesian inference as well as provide several algorithms for performing ABC. Chapters also apply some of the algorithms in a tutorial fashion, with one specific application to the Minerva 2 model. In addition, the book discusses several applications of ABC methodology to recent problems in cognitive science.

Likelihood-Free Methods for Cognitive Science will be of interest to researchers and graduate students working in experimental, applied, and cognitive science.

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http://nitroflare.com/view/9E6E903229653C7/331972424X.pdf

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Distracted: How Regulations Are Destroying the Practice of Medicine and Preventing True Health-Care Reform

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Mar 092018
 

After the many bureaucratic changes that followed the passing of the Affordable Care Act (Obamacare) and other legislation, patient care has become secondary to satisfying the whims of government and giant insurance company administrators, who are in total control.

The result is a web of complicated rules and misguided programs whose chief effect has been to distract doctors and nurses from their proper focus on patient care. Access to health care now depends on the ability of patients, doctors, and nurses to navigate in and around this cumbersome and ever-changing system.

Written by a practicing doctor and based on years of real-life experience, Distracted takes the unique view that it is not the American health care system that is broken—the problem lies in the administration of health care. The solution is simplicity where there is complexity. The solution is an elegant use of health information technology to foster improved care. It is putting control of health care decisions back with those who know best, patients and their health care teams.

The solution is caring for patients with fewer distractions.

 

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http://nitroflare.com/view/E5056C3F21E13A6/Distracted_-_Matthew_Hahn%2C_MD.epub

 

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Planning Quality Project Management of (EMR/EHR) Software Products

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Mar 092018
 

When hospitals began implementing their electronic medical records/electronic health records systems (EMR/HER) the pharmaceutical companies that were conducting clinical trials at those hospitals wanted to sue the date from those systems instead of having the hospitals enter the data in their EHR systems and also in the study data entry system. However, the FDA regulations would require that the hospital systems be “validated”. The hospitals and the companies developing the systems argued that was “over-regulation.” HIMSS published their Developer Code of Conduct where they said instead they would use Quality Management techniques.

This book covers how to use Quality Management (ISO 9001) to develop computer systems, specifically EMR systems. It gives a basic introduction to how to implement computer systems. It also covers the topic of compliance because the hospitals are required to comply with regulations other than FDS regulations.

The book also discusses the topics of risk management and conducting audits, both of which are part of ISO 9001 quality management of computer systems. The book is designed to give the reader an introduction to the things you have to do when implementing a computer system that has to satisfy some standards and where the accuracy of the information could impact the accuracy of a person’s medical treatment.

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http://nitroflare.com/view/90277FAFCEC3BC5/1138310182.pdf

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Service Extraordinaire: Unlocking the Value of Concierge Medicine

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Mar 092018
 

Concierge medicine represents a relatively novel health care delivery model that is becoming more appealing both to providers and patients because of its potential to improve quality and value in health care. A gap exists in the current literature regarding the benefits and challenges associated with concierge medicine as well as best practices for developing and sustaining a successful, patient-centered concierge practice. This book aims to close the gap by discussing the role of concierge medicine in the context of the evolving U.S. healthcare system and the changes produced by the Affordable Care Act. It will address questions about affordability, access, quality, value, communication, technology, and patient-centered care, and will include real-world best practice examples from a successful concierge medicine practice.
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Teaching and Learning in Physical Therapy : From Classroom to Clinic, Second Edition

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Mar 092018
 


Teaching and Learning in Physical Therapy: From Classroom to Clinic, Second Edition is based on the teaching, research, and professional experiences of Drs. Margaret Plack and Maryanne Driscoll, who together have over 60 years of experience. More importantly it contains practical information that allows students, educators, and clinicians to develop optimal instructional strategies in a variety of settings. Clinical scenarios and reflective questions are interspersed throughout, providing opportunities for active learning, critical thinking, and immediate direct application.

Grounded in current literature, the Second Edition is geared for physical therapists, physical therapist assistants, students, educators, and other health care professionals. By extending the principles of systematic effective instruction to facilitate critical thinking in the classroom and the clinic, and providing strategies to enhance communication and collaboration, the Second Edition has a strong theoretical basis in reflective practice, active learning strategies, and evidence-based instruction.

Features:

– A user-friendly approach integrating theory and practical application throughout
– Classroom/clinical vignettes along with integrative problem solving activities and reflective questions to reinforce concepts
– Key points to remember and chapter summaries throughout
– Updated references and suggested readings at the end of each chapter

In physical therapy, teaching and learning are lifelong processes. Whether you are a student, clinician, first time presenter, or experienced faculty member, you will find Teaching and Learning in Physical Therapy: From Classroom to Clinic, Second Edition useful for enhancing your skills both as a learner and as an educator in physical therapy.

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http://nitroflare.com/view/F4CB903CDF6754B/Teaching_and_Learning_in_Physical.pdf

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Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself

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Mar 072018
 

With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity

Why do we age? Why does cancer develop? What’s the connection between heart failure and Alzheimer’s disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.

In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it’s the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years.

Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.

 

 

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http://nitroflare.com/view/1EACBCA64859B63/1603587675.epub

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How to Sleep

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Mar 052018
 

Sleep is quite a popular activity, indeed most humans spend around a third of their lives asleep. However, cultural, political, or aesthetic thought tends to remain concerned with the interpretation and actions of those who are awake. How to Sleep argues instead that sleep is a complex vital phenomena with a dynamic aesthetic and biological consistency.

Arguing through examples drawn from contemporary, modern and renaissance art; from literature; film and computational media, and bringing these into relation with the history and findings of sleep science, this book argues for a new interplay between biology and culture. Meditations on sex, exhaustion, drugs, hormones and scientific instruments all play their part in this wide-ranging exposition of sleep as an ecology of interacting processes.

How to Sleep builds on the interlocking of theory, experience and experiment so that the text itself is a lively articulation of bodies, organs and the aesthetic systems that interact with them. This book won’t enhance your sleeping skills, but will give you something surprising to think about whilst being ostensibly awake.

Review
Matthew Fuller has composed a revelatory and brilliantly original book. This richly insightful and multifaceted work will be indispensable reading for anyone concerned with the increasingly urgent problem of sleep. – Jonathan Crary, Meyer Schapiro Professor of Modern Art and Theory, Columbia University, USA Where do you fall when you fall asleep? Out of consciousness and into a state of quasi-death, or into an unconscious form of activity? Do you withdraw from the world or get projected upon it differently? Who is the subject of sleep? Like love, sleep makes us creative and vulnerable at the same time. It is a democratic state, yet inaccessible to phenomenological accounts: it does not even make sense to state: “I am asleep”, and yet sleep deprivation is torture. Arguing passionately that sleep is both our posthuman, animal core and a form of power, this original volume performs a series of sleep acts, ranging from insomnia, apnea, narcolepsy, to sleep-walking, doziness, cataplexy and plain not wanting to wake up. In a brilliant combination of aphorisms, meditations, snippets of self-help and shreds of critical analysis, the book explores the bio-politics of sleep, as well as its social, psychological and aesthetic aspects. This is Matthew Fuller at his best: witty, theoretically sharp and thoroughly enjoying his inimitable flair for paradoxes. – Rosi Braidotti, Distinguished University Professor and founding Director of the Centre for the Humanities at Utrecht University, The Netherlands

 

 

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Biomimetic Nanotechnology

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Mar 052018
 

The human body includes very effective and efficient technology, such as light receptors (eyes), chemical receptors (tongue and nose), and movement (muscles). This book explains how these functions work on the molecular level and then discusses nanotechnology that uses the same structure-function relationships.

 

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Managing Discovery in the Life Sciences

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Mar 042018
 

In this book, distinguished scholars Philip A. Rea, Mark V. Pauly, and Lawton R. Burns explore the science and management behind marketable biomedical innovations. They look at how the science actually played out through the interplay of personalities, the cultures within and between academic and corporate entities, and the significance of serendipity not as a mysterious phenomenon but one intrinsic to the successes and failures of the experimental approach. With newly aggregated data and case studies, they consider the fundamental economic underpinnings of investor-driven discovery management, not as an obstacle or deficiency as its critics would contend or as something beyond reproach as some of its proponents might claim, but as the only means by which scientists and managers can navigate the unknowable to discover new products and decide how to sell them so as to maximize the likelihood of establishing a sustainable pipeline for still more marketable biomedical innovations.

Advance praise: ‘The authors captured the magic of the biomedical industry from the inception of an idea through translational studies that lead to a product that can transform lives. Case studies illustrate the importance of scientific understanding, long periods of experimentation, willingness to take risks. This book is a ‘must read’ for anyone who wants to better understand drug discovery.’ P. Roy Vagelos, Chairman, Regeneron Pharmaceuticals, Inc

Advance praise: ‘This new study by Philip A. Rea, Mark V. Pauly, and Lawton R. Burns provides useful information and insightful analyses of the biomedical innovation process.’ Henry Grabowski, Professor Emeritus of Economics, Duke University, North Carolina

Philip A. Rea, Professor of Biology and Rebecka and Arie Belldegrun Distinguished Director, co-founded the Roy and Diana Vagelos Program in Life Sciences and Management at the University of Pennsylvania. A Fellow of the American Association for the Advancement of Science, he has received several prestigious prizes and awards for his pioneering research on membrane transporters and his creative science teaching, including the President’s Medal of the Society for Experimental Biology and a Lindback Foundation Award for Distinguished Teaching.

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http://nitroflare.com/view/98E191969C69AA7/1107130905.pdf

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