Jan 082017
 

Statistical Techniques for Neuroscientists (Frontiers in Neuroscience)


Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein.

The book examines current statistical methods for solving emerging problems in neuroscience. These methods have been applied to data involving multichannel neural spike train, spike sorting, blind source separation, functional and effective neural connectivity, spatiotemporal modeling, and multimodal neuroimaging techniques. The author provides an overview of various methods being applied to specific research areas of neuroscience, emphasizing statistical principles and their software. The book includes examples and experimental data so that readers can understand the principles and master the methods.

The first part of the book deals with the traditional multivariate time series analysis applied to the context of multichannel spike trains and fMRI using respectively the probability structures or likelihood associated with time-to-fire and discrete Fourier transforms (DFT) of point processes. The second part introduces a relatively new form of statistical spatiotemporal modeling for fMRI and EEG data analysis. In addition to neural scientists and statisticians, anyone wishing to employ intense computing methods to extract important features and information directly from data rather than relying heavily on models built on leading cases such as linear regression or Gaussian processes will find this book extremely helpful.

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Jan 062017
 

Essentials of a Successful Biostatistical Collaboration (Chapman & Hall/CRC Biostatistics Series)


By (author): Arul Earnest

The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field. The book provides valuable insight on where to look for information and material on sample size and statistical techniques commonly used in clinical research, and on how best to communicate with clinicians. It also covers the best practices to adopt in terms of project, time, and data management; relationship with collaborators; etc.

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Dec 292016
 

Clinical and Statistical Considerations in Personalized Medicine (Chapman & Hall/CRC Biostatistics Series)


The Future of Clinical Research and Health Care: From Empirical to Precision Medicine
Clinical and Statistical Considerations in Personalized Medicine explores recent advances related to biomarkers and their translation into clinical development. Leading clinicians, biostatisticians, regulators, commercial professionals, and researchers address the opportunities and challenges in successfully applying biomarkers in drug discovery and preclinical and clinical development.

Robust Biomarkers for Drug Development and Disease Treatment
The first four chapters discuss biomarker development from a clinical perspective. Coverage ranges from an introduction to biomarkers to advances in RNAi screens, epigenetics, and rare diseases as targets for personalized medicine approaches. Subsequent chapters examine the statistical considerations in applying a personalized medicine approach, including multiplicity in pharmacogenomics. The last chapter assesses the regulatory issues involved in using biomarkers.

Improve Patient Care and Reduce Costs and Side Effects
Despite the vast amount of literature on biomarkers, there is no comprehensive book that integrates the clinical and statistical components. This book is one of the first to incorporate both the clinical and statistical aspects of biomarkers in the personalized medicine paradigm. Covering a wide spectrum of personalized medicine-related topics, it presents state-of-the-art techniques for advancing the application of biomarkers in drug discovery and development.

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Dec 262016
 

High-Yield™ Biostatistics (High-Yield Series)


Features: Used Book in Good Condition
By (author): MD, PhD. Anthony N. Glaser

Part of the successful High-Yield™ Series, High-Yield™ Biostatistics, Second Edition explains concepts, provides examples, and covers the complete range of biostatistics material that can be expected to appear on the USMLE Step 1. New to this edition are references to evidence-based medicine, and information updated to reflect changes in the current USMLE examinations.
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Dec 242016
 

A Concise Guide to Clinical Trials


Features: Used Book in Good Condition
By (author): Allan Hackshaw

Clinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research. They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide variety of interventions, including drugs, devices, surgical techniques, and changes in behaviour and lifestyle.

A Concise Guide to Clinical Trials provides a comprehensive yet easy-to-read overview of the design, conduct and analysis of trials. It requires no prior knowledge on the subject as the important concepts are introduced throughout. There are chapters that distinguish between the different types of trials, and an introduction to systematic reviews, health-related quality of life and health economic evaluation. The book also covers the ethical and legal requirements in setting up a clinical trial due to an increase in governance responsibilities and regulations.

This practical guidebook is ideal for busy clinicians and other health professionals who do not have enough time to attend courses or search through extensive textbooks. It will help anyone involved in undertaking clinical research, or those reading about trials. The book is aimed at:

  • Those wishing to learn about clinical trials for the first time, or as a quick reference guide, for example as part of a taught course on clinical trials
  • Health professionals who wish to conduct their own trials, or participate in other people’s studies
  • People who work in pharmaceutical companies, grant funding organisations, or regulatory agencies
List Price: $69.95 USD
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Dec 242016
 

Medical Statistics at a Glance Workbook


Features: Used Book in Good Condition
By (author): Aviva Petrie, Caroline Sabin

This comprehensive workbook contains a variety of self-assessment methods that allow readers to test their statistical knowledge, put it into practice, and apply it in a medical context, while also providing guidance when critically appraising published literature. It is designed to support the best-selling third edition of Medical Statistics at a Glance, to which it is fully cross-referenced, but may be used independently of it.

Ideal for medical students, junior doctors, researchers and anyone working in the biomedical and pharmaceutical disciplines who wants to feel more confident in basic medical statistics, the title includes:

• Over 80 MCQs, each testing knowledge of a single statistical concept or aspect of study interpretation
• 29 structured questions  to explore in greater depth several statistical techniques or principles, including  the choice of appropriate statistical analyses and the interpretation of study findings
• Templates for the appraisal of clinical trials and observational studies, plus full appraisals of two published papers to demonstrate the use of these templates in practice
• Detailed step-by-step analyses of two substantial data sets (also available at www.medstatsaag.com) to demonstrate the application of statistical procedures to real-life research

Medical Statistics at a Glance Workbook is the ideal resource to test statistical knowledge and improve analytical and interpretational skills.

Additional resources are available at www.medstatsaag.com, including:
• Excel datasets to accompany the data analysis section
• Downloadable PDFs of two templates for critical appraisal
• Links to online further reading
• Supplementary MCQs

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Dec 242016
 

Essentials of Medical Statistics


Features: Blackwell Publishers
By (author): Betty Kirkwood, Jonathan Sterne

Blackwell Publishing is delighted to announce that this book has been Highly Commended in the 2004 BMA Medical Book Competition. Here is the judges’ summary of this book:

“This is a technical book on a technical subject but presented in a delightful way. There are many books on statistics for doctors but there are few that are excellent and this is certainly one of them. Statistics is not an easy subject to teach or write about. The authors have succeeded in producing a book that is as good as it can get. For the keen student who does not want a book for mathematicians, this is an excellent first book on medical statistics.”

Essential Medical Statistics is a classic amongst medical statisticians. An introductory textbook, it presents statistics with a clarity and logic that demystifies the subject, while providing a comprehensive coverage of advanced as well as basic methods.

The second edition of Essential Medical Statistics has been comprehensively revised and updated to include modern statistical methods and modern approaches to statistical analysis, while retaining the approachable and non-mathematical style of the first edition. The book now includes full coverage of the most commonly used regression models, multiple linear regression, logistic regression, Poisson regression and Cox regression, as well as a chapter on general issues in regression modelling. In addition, new chapters introduce more advanced topics such as meta-analysis, likelihood, bootstrapping and robust standard errors, and analysis of clustered data.

Aimed at students of medical statistics, medical researchers, public health practitioners and practising clinicians using statistics in their daily work, the book is designed as both a teaching and a reference text. The format of the book is clear with highlighted formulae and worked examples, so that all concepts are presented in a simple, practical and easy-to-understand way. The second edition enhances the emphasis on choice of appropriate methods with new chapters on strategies for analysis and measures of association and impact.

Essential Medical Statistics is supported by a web site at www.blackwellpublishing.com/essentialmedstats. This useful online resource provides statistical datasets to download, as well as sample chapters and future updates.

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Dec 202016
 

Medical Statistics from Scratch: An Introduction for Health Professionals


Features: Wiley-Interscience

Correctly understanding and using medical statistics is a key skill for all medical students and health professionals.

In an informal and friendly style, Medical Statistics from Scratch provides a practical foundation for everyone whose first interest is probably not medical statistics. Keeping the level of mathematics to a minimum, it clearly illustrates statistical concepts and practice with numerous real world examples and cases drawn from current medical literature.

This fully revised and updated third edition includes new material on: 

  • missing data, random allocation and concealment of data
  • intra-class correlation coefficient
  • effect modification and interaction
  • diagnostic testing and the ROC curve
  • standardisation

Medical Statistics from Scratch is an ideal learning partner for all medical students and health professionals needing an accessible introduction, or a friendly refresher, to the fundamentals of medical statistics.

List Price: $57.95 USD
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Dec 192016
 

Clinical Trials with Missing Data: A Guide for Practitioners (Statistics in Practice)


By (author): Michael O’Kelly, Bohdana Ratitch

This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable.

The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively.

The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included – the reader is given a toolbox for implementing analyses under a variety of assumptions.

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Dec 162016
 

Statistical Methods for Healthcare Performance Monitoring (Chapman & Hall/CRC Biostatistics Series)


By (author): Alex Bottle, Paul Aylin

Healthcare is important to everyone, yet large variations in its quality have been well documented both between and within many countries. With demand and expenditure rising, it’s more crucial than ever to know how well the healthcare system and all its components – from staff member to regional network – are performing. This requires data, which inevitably differ in form and quality. It also requires statistical methods, the output of which needs to be presented so that it can be understood by whoever needs it to make decisions.

Statistical Methods for Healthcare Performance Monitoring covers measuring quality, types of data, risk adjustment, defining good and bad performance, statistical monitoring, presenting the results to different audiences and evaluating the monitoring system itself. Using examples from around the world, it brings all the issues and perspectives together in a largely non-technical way for clinicians, managers and methodologists.

Statistical Methods for Healthcare Performance Monitoring is aimed at statisticians and researchers who need to know how to measure and compare performance, health service regulators, health service managers with responsibilities for monitoring performance, and quality improvement scientists, including those involved in clinical audits.

List Price: $89.95 USD
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