Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment

 Epidemiology, Pathology, Physiology  Comments Off on Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment
May 032018
 

A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists.

Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors.

This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.

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Hemodynamic Rounds: Interpretation of Cardiac Pathophysiology from Pressure Waveform Analysis

 Cardiovascular, Pathology, Physiology  Comments Off on Hemodynamic Rounds: Interpretation of Cardiac Pathophysiology from Pressure Waveform Analysis
May 022018
 

The essential resource on cardiac hemodynamics now in a new edition

Hemodynamic Rounds, Fourth Edition is intended to help cardiologists, cardiovascular fellowship trainees, residents and other members of the medical community enhance their understanding of cardiac physiology and its associated hemodynamic presentations in health and disease. This includes the basic principles of flow and pressure measurements, systemic as well as coronary hemodynamics in normal and diseased states, and changes in hemodynamics following interventional procedures ranging from TAVI and valvuloplasty to stent placement.

Like its popular predecessors, this new edition draws on case studies to illustrate characteristic cardiac hemodynamic findings and discusses the essential methods used in interpreting pressure waveforms as a diagnostic and monitoring tool.

The text is organized into chapters on specific areas of the heart, common cardiac pathophysiologic conditions, and hemodynamic situations resulting from different therapeutic procedures. It includes discussions of both normal and abnormal pressure waveforms. This new edition has been revised throughout to include brand new content on aortic and mitral valve stenosis and regurgitation as well as TAVI and mitral clip hemodynamics. Highlights include:

Essential and easy to understand resource for those required to interpret cardiac blood flow and blood pressure tracings
Covers hemodynamic assessment by cardiac disorder, plus the bedside applications of hemodynamics
Revised throughout and includes brand new content on valve stenosis and regurgitation and TAVI and mitral clip hemodynamics
Hemodynamic Rounds: Interpretation of Cardiac Pathophysiology from Pressure Waveform Analysis, Fourth Edition is an indispensable tool for all physicians, nurses, and students responsible for measuring and interpreting cardiac waveforms in cardiac diagnosis and monitoring.

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Coordinating Organismal Physiology Through the Unfolded Protein Response

 Physiology  Comments Off on Coordinating Organismal Physiology Through the Unfolded Protein Response
May 022018
 

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.
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Examination Questions and Answers in Basic Anatomy and Physiology: 2400 Multiple Choice Questions, Second Edition

 Anatomy, Physiology  Comments Off on Examination Questions and Answers in Basic Anatomy and Physiology: 2400 Multiple Choice Questions, Second Edition
Apr 182018
 

This second edition provides 2400 multiple choice questions on human anatomy and physiology, and some physical science, separated into 40 categories. The answer to each question is accompanied by an explanation. Each category has an introduction to set the scene for the questions to come. However, not all possible information is provided within these Introductions, so an Anatomy and Physiology textbook is an indispensable aid to understanding the answers. The questions have been used in end-of-semester examinations for undergraduate anatomy and physiology courses and as such reflect the focus of these particular courses and are pitched at this level to challenge students that are beginning their training in anatomy and physiology.
The question and answer combinations are intended for use by teachers, to select questions for their next examinations, and by students, when studying for an upcoming test. Students enrolled in the courses for which these questions were written include nursing, midwifery, paramedic, physiotherapy, occupational therapy, nutrition and dietetics, health sciences, exercise science, and students taking an anatomy and physiology course as an elective.

 

 

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Pruritus, Second Edition

 Physiology  Comments Off on Pruritus, Second Edition
Apr 162018
 

This book provides a thorough and comprehensive reference in the management of pruritus, designed to be a convenient resource for all physicians confronted with patients suffering from itch. The Editors have recruited a board of internationally renowned experts to provide an in-depth analysis of the causes and management of pruritus, including the current concepts in pathophysiology and novel therapeutics.
Acute and chronic pruritus can represent significant management issues both as a common physiological sensation and as a manifestation of dermatologic and non-dermatologic diseases. All patients suffering from itch know that it is a very awkward sensation. Unfortunately, this often significant symptom is frequently considered less severe in comparison with pain. The consequences are that research on this field has been poorer than research on pain and that pruritus is therefore more difficult to treat.
Pruritus, Second edition addresses the new concepts and discoveries that have modified our understanding of this condition. It explains the pathophysiology of itch, describes all causes, and provides guidelines for management and treatment.
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Ocular and Visual Physiology: Clinical Application

 Physiology  Comments Off on Ocular and Visual Physiology: Clinical Application
Apr 142018
 

This book meets the growing demand among ophthalmologists, optometrists and orthoptists, in training and in practice, as well as visual neuroscientists, to have a clear, succinct and well-written textbook to objectively cover the subject of ocular and visual physiology.
Ocular and visual physiology is a core knowledge component for these disciplines, and yet is often difficult to understand. However, this book clearly conveys the simple elegance of the relationship between structure and function that is the hallmark of understanding the physiology of the eye and visual system. Ocular and Visual Physiology – Clinical Application is essential reading for any one hoping to have a clear understanding of the subject. Students will find it a great resource to pass their exams.
Each of the chapters has been independently reviewed and edited by an expert in the field with a clinical or visual scientific academic background. The text is based on the latest publications in peer-reviewed journals that are closely referenced within the body of the text.
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Trauma Induced Coagulopathy

 Pathology, Physiology  Comments Off on Trauma Induced Coagulopathy
Mar 282018
 

Outlines the current concepts that define trauma induced coagulopathy
Written by experts in the field
Provides a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy

This text is aimed at defining the current concepts that define trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It will serve as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader will have full understanding of the tests that are used to study trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications are reviewed in detail.
Trauma Induced Coagulopathy will also be a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy.

 

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Pathophysiology Made Incredibly Visual!, Third Edition

 Pathology, Physiology  Comments Off on Pathophysiology Made Incredibly Visual!, Third Edition
Mar 272018
 

Know the how and why of common conditions—and assess them accurately—with the newly updated Pathophysiology Made Incredibly Visual, 3rd Edition.

Fully illustrated in the popular Made Incredibly Visual style, this essential guide offers easy-to-follow explanations for the causes and mechanisms of numerous common disorders, listing symptoms and indications for each. Use this as the perfect study guide for the NCLEX® or certification exam, to support class materials, and to absorb the pathophysiology principles every nurse needs to know.

Absorb the expert wisdom and insights of this invaluable guide…

– Walks you through the development stages of numerous diseases and disorders, illustrating their cellular process, symptoms, and effects on tissue and organs
– Explains cell parts and their functions, as well as cell division, adaptation, injury, and stress and disease
– Hundreds of photos, illustrations, and diagrams explaining key concepts and providing clear direction on how to recognize common conditions
– Supports accurate diagnosis and treatment – Common disorders for each major body system, such as:

* Cardiovascular – Acute coronary syndromes, aortic aneurysms, cardiomyopathy
* Respiratory – ARDS, asthma, chronic bronchitis, lung cancer
* Neurologic – Alzheimer’s, cerebral aneurysm, migraine headaches
* Gastrointestinal – Cholecystitis, cirrhosis, Crohn’s disease
* Musculoskeletal – Carpal tunnel syndrome, herniated disk, osteoarthritis
* Hematologic – Anemia, leukemia, sickle cell disease
* Immune – AIDS, allergic rhinitis, rheumatoid arthritis
* Endocrine – Adrenal hypofunction, diabetes mellitus, metabolic syndrome
* Renal – Acute renal failure, acute tubular necrosis, pyelonephritis
* Integumentary – Acne, burns, pressure ulcers
* Reproductive – Breast, cervical, ovarian, and prostate cancer.

 

 

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Oral Candidosis: Physiopathology, Decision Making, and Therapeutics

 Pathology, Physiology  Comments Off on Oral Candidosis: Physiopathology, Decision Making, and Therapeutics
Mar 272018
 

This book on oral candidosis is for dentists and related professionals who require a straightforward update on the important new advances relating to physiopathology, virulence and treatment. Essential concepts and advanced discoveries are presented in user-friendly language with the aim of providing a trustworthy reference guide that can be rapidly consulted whenever necessary. The rich and colorful photos have been carefully chosen to illustrate each theme and provide the reader with helpful visual support; informative diagrams, tables and charts are also included. The authors – dentists, physicians and pharmacists – have been selected on the basis of their expertise and scientific reputation. All of these “candidologists” have invested great effort in generating a unique and remarkable work that successfully translates scientific jargon into clinically relevant language.

 

 

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The Mammalian Auditory Pathways: Synaptic Organization and Microcircuits

 Physiology  Comments Off on The Mammalian Auditory Pathways: Synaptic Organization and Microcircuits
Mar 132018
 

The auditory system is a complex neural system composed of many types of neurons connected into networks. One feature that sets the auditory system apart from other sensory systems, such as somatosensory or visual systems, is the many stages of neural processing that occur between the ear in the periphery and the cerebral cortex. Each stage is composed of specialized types of neurons connected in specific microcircuits that perform computations on the information about sound.
To understand this processing, all the tools of neuroscience must be employed. The proposed text integrates cell biology, synaptic physiology, and electrophysiology to fully develop the topic, presenting an overview of the functional anatomy of the central auditory system. It is organized based on the neuronal connectivity of the central auditory system, which emphasizes the neurons, their synaptic organization, and their formation of functional pathways and microcircuits. The goal of the book is to stimulate research into the cell biology of the central auditory system and the characteristics of the specific neurons and connections that are necessary for normal hearing. Future research on the development of the central auditory including that employing stem cells will require such information in order to engineer appropriate therapeutic approaches.

 

 

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