This book is made possible by the enthusiastic contributions of the authors of the chapters. They have been invited from young and active scientists in the field of t-PA research. I am grateful for their contribution and for the fact that all accepted the specifications of their chapter in order to obtain a structured book. Inevitably, some overlap does exist; on the one hand to enable controversial or unsettled areas to be discussed by the different experts with a different approach and background.It is a particular pleasure and honor that Dr. T. Astrup, as an eye-witness and essential contributor to the history of t-PA discovery and research, gives a unique account of the history of t-PA research in the first chapter of the book.
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This highly readable and comprehensive overview of psychophysiology provides information regarding the anatomy and physiology of various body systems, methods of recording their activity, and ways in which these measures relate to human behavior. Biofeedback applications are contained in a separate chapter and discussions of stress management, job strain, and personality factors that affect cardiovascular reactivity are presented. There is much of interest here to the student, researcher, and clinician in behavioral medicine, ergonomics, emotion, cognitive neuroscience, neuropsychology, and health psychology.
Now in its fourth edition, Andreassi’s Psychophysiology explores some of the newer areas of importance and updates findings in traditional topics of interest. Significant changes to this edition include:
*updated information on brain activity in memory, perception, and intelligence;
*new information on brain imaging and behavior;
*separate chapters on pupillography and eye movements;
*new information on the startle pattern and eyeblink;
*separate chapters on clinical and non-clinical applications;
*updated information on cardiovascular reactivity and personality;
*the latest biofeedback and ergonomics applications;
*novel findings in environmental psychophysiology;
*brief summaries at the end of each section; and
*an appendix on laboratory safety
Each chapter is a self-contained unit allowing instructors to customize the presentation of the material. With over 1,700 citations, Andreassi’s Psychophysiology is the definitive text in the field.
An instructor’s manual is now available. Based on the book, the manual is primarily a test bank to be used in giving examinations to students during the teaching of a course. Both multiple-choice and essay questions have been provided, along with lists of key terms and ideas. These can be used for definition-type questions and to highlight important concepts, as well as alerting the instructor to important terms and ideas that they may want to cover in lectures. Sample syllabi are provided for teaching a course at both undergraduate and graduate levels to help the instructor who is preparing a course for the first time. A number of possible laboratory exercises are also provided that can be carried out in conjunction with teaching the course.
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Pathophysiology Flash Cards contain 240 clinical cases that challenge you to apply principles to real life scenarios.
Each two-sided card features a clinical case and challenges you to diagnose the condition
Provides a clear explanation of the underlying physiology
Allows you to brush up on system-specific disorders
A super-effective way to prepare for pathophysiologycourses and board exams
Student and peer reviewed for the most relevant material possible
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Recent determination of genome sequences for a wide range of bacteria has made in-depth knowledge of prokaryotic metabolic function essential in order to give biochemical, physiological, and ecological meaning to the genomic information. Clearly describing the important metabolic processes that occur in prokaryotes under different conditions and in different environments, this advanced text provides an overview of the key cellular processes that determine bacterial roles in the environment, biotechnology, and human health. Prokaryotic structure is described as well as the means by which nutrients are transported into cells across membranes. Glucose metabolism through glycolysis and the TCA cycle are discussed, as well as other trophic variations found in prokaryotes, including the use of organic compounds, anaerobic fermentation, anaerobic respiratory processes, and photosynthesis. The regulation of metabolism through control of gene expression and control of the activity of enzymes is also covered, as well as survival mechanisms used under starvation conditions.
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The leading physiology book on the market, this bestselling title in the Board Review Series offers a concise, highly efficient review of all essential physiology concepts covered in the first and second year of medical school, as well as more than 350 clinical vignette-style multiple-choice questions to help students prepare for course exams and practice for the USMLE Step 1. Abundant illustrations, flow charts, and tables facilitate study. An interactive question bank on thePoint uses the same chapter and comprehensive exam questions from the book to provide interactive exam practice online.
Students will appreciate the book’s comprehensive, yet efficient assistance in preparing for course exams as well as the USMLE Step 1.
Instructors will welcome the masterful educational approach of Linda S. Costanzo, PhD, who excels in communicating complex physiology concepts in an accessible manner. A comprehensive image bank on thePoint makes preparing lecture slides a snap.
A concise outline format and bolded key terms enable efficient review and exam preparation.
Discussions of clinical disorders, integrated throughout the text, correlate physiology concepts to the practice of medicine.
Chapter overviews and summaries offer a quick introduction and review of key topics and information, to maximize study time.
More than 350 multiple-choice questions and answers, many of them new and revised, help students prepare for course and board exams. These include many new multi-part questions that challenge students’ decision-making skills.
Detailed answers and explanations for every question, cross-referenced back to the text, allow students to remediate weak areas of knowledge.
New appendices allow for an efficient review of Key Physiology Topics for USMLE Step I, Key Physiology Equations for USMLE Step I, and Normal Blood Values.
130 outstanding full-color figures and flow diagrams and 50 tables, many of them new, allow for efficient assimilation of complex information, and are included in the instructor Image Bank on ThePoint.
Significant updates throughout present the latest physiology knowledge, including expanded coverage of cellular, respiratory, renal, gastrointestinal, and endocrine physiology.
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This innovative text explores the cellular transport of organic cations, from functional and structural properties to pharmacological implications and psychiatric developments. The authoritative chapters introduce organic cation transporters and then proceed to discuss their mechanisms such as binding of substrates and inhibitors; their drug dispositions and toxicity; their relationships to genetic and pathophysiological variability; and their roles in endocrine, metabolic, and neurological systems. The final chapters delve into the use of animal models for the study of organic cation transporter function and their possible use in environmental cycling of pharmaceutical residues.
This comprehensive volume. unites integrative transporter physiology with structural and molecular biology, genetics, pharmacology and pathophysiology, offering a holistic approach to utilizing this novel technique in physiological contexts. It will prove invaluable reading for researchers and students in various areas of integrative, organ, cell and molecular physiology as well as pharmacologists and neurologists.
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