Spicy Magazines for Men! ;-) Home eBooks & eLearning Pharmacology for Podiatrists

 Pharmacology  Comments Off on Spicy Magazines for Men! ;-) Home eBooks & eLearning Pharmacology for Podiatrists
Feb 052019
 

Proposed changes in practice legislation will allow podiatrists to prescribe a limited range of drugs and dressings. It is therefore now imperative that students and practitioners understand pharmacology. Not only the mechanisms of action of drugs, but also their potential side-effects and interactions with other drugs taken by the patient. This book will cover both basic and clinical pharmacology. The podiatrist’s role in examination, assessment and diagnosis are considered.Content: Chapter 1 Introduction (pages 1–20): Chapter 2 How Drugs Work (pages 21–32): Chapter 3 The Role of the Podiatrist in Patient Care (pages 33–46): Chapter 4 Drugs Affecting the Peripheral Nervous System (pages 47–55): Chapter 5 Drugs Affecting the Central Nervous System (pages 56–75): Chapter 6 Drugs Affecting the Gastrointestinal System (pages 76–84): Chapter 7 Drugs Affecting the Cardiovascular System (pages 85–117): Chapter 8 Drugs Affecting the Respiratory System (pages 118–126): Chapter 9 Chemotherapeutic Drugs (pages 127–139): Chapter 10 Drugs Affecting the Endocrine System (pages 140–151): Chapter 11 Drugs Affecting the Urinary Tract (pages 152–160): Chapter 12 Drugs Affecting the Reproductive System (pages 161–171): Chapter 13 Drugs Affecting the Musculoskeletal System (pages 172–177): Chapter 14 Drugs Affecting the Eye and Ear (pages 178–187): Chapter 15 Drugs Acting on the Skin (pages 188–192): Chapter 16 Local Anaesthetics (pages 193–195): Chapter 17 Cytotoxic Drugs (pages 196–199):
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Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life, Fifth Edition

 Ob/Gynae, Pediatrics, Pharmacology  Comments Off on Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life, Fifth Edition
Feb 042019
 

The Neonatal Formulary is a unique book providing advice on the safe use of drugs during pregnancy, labour and throughout the first year of life. Thoroughly updated, this fifth edition draws on the experience of an increasingly international group of neonatologists and is now a well established reference on prescribing in infancy. It covers all the drugs commonly used in the perinatal period, including those used for fetal treatment, and summarizes how the prescribing of each has to adapt to changes in drug elimination during the first year of life.   Key features for the fifth edition include: fully updated monographs and references20 full monographs for diseases more commonly seen in the tropicsinvaluable information on dose sizes and administration for babiesfurther inclusion of evidence from relevant RCTs and systematic reviews from the Cochrane databasea free access website with regular updates and links to other useful information. IMPORTANT DOSAGE CHANGEContent:
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Polysaccharide Applications. Cosmetics and Pharmaceuticals

 Pharmacology  Comments Off on Polysaccharide Applications. Cosmetics and Pharmaceuticals
Feb 012019
 

Content: Alginate microparticles for vaccine delivery / M.A. Suckow, L. Siger, T.L. Bowersock, J.J. Turek, D. Van Horne, D. Borie, A. Taylor, H. Park, and K. Park — Gene delivery by quaternary chitosan with antennary galactose residues / Tatsuro Ouchi, Jun-ichi Murata, and Yuichi Ohya — Drug-cyclodextrin complexation in the presence of water-soluble polymers : enhanced solubility and percutaneous transport / Már Másson and Thorsteinn Loftsson — Preparation of polyrotaxanes and molecular tubes for host-guest systems / Pierandrea LoNostro, Massimo Ceccato, and Piero Baglioni — Cyclodextrin-linked chitosan : synthesis and inclusion complexation abilities / Nobuo Sakairi, Norio Nishi, and Seiichi Tokura — Preparation of inclusion foams from chitin and PEG-chitin for the drug delivery system / S. Tokura, H. Tamura, T. Dohba, K. Takahashi, N. Sakairi, and N. Nishi — Polysaccharide engineering : silicified microcrystalline cellulose as a novel high-functionality pharmaceutical material / Stephen Edge, D. Fraser Steele, Michael J. Tobyn, and John N. Staniforth — Synthesis and characterization of thermoreversible sucrose hydrogels (sucrogels) / Seongbong Jo and Kinam Park — Investigations on cellulose-carbanilates and cellulose-carbanilate-acetates in dilute solutions / Kati Schmidt, Frank-Immo Hildebrandt, and Peter Zugenmaier — Molten inorganic salt hydrates as cellulose solvents / S. Fischer, H. Leipner, E. Brendler, W. Voigt, and K. Fischer — Cellulosic liquid crystals / Pierre Sixou — Chitosan-pluronic physical interpenetrating network : membrane fabrication and protein permeability studies / Derrick Anderson, Tragiang Nguyen, and Mansoor Amiji — Interactions between cyclodextrins and a mixed cationic cellulose ether : anionic surfactant gelling system / Paschalis Alexandridis, Sungsook Ahn, and Marina Tsianou — Interaction between chitin derivatives and surfactants / J. Desbrières and M. Rinaudo — Influence of cationic cellulose structure on interactions with sodium dodecyl sulfate / Melissa Manuszak Guerrini and William H. Daly — Creaming and rheology of flocculated emulsions / Pretima Manoj, Andrew D. Watson, Annette J. Fillery-Travis, David J. Hibberd, and Margaret M. Robins — Building aqueous viscosity through synergistic polymer-polymer interactions / James V. Gruber and Peter N. Konish — Ultrasonic techniques to characterize concentrated colloidal dispersions / D.J. Hibberd, M.J. Garrood, J.M. Leney, and M.M. Robins — Fluorescence microscopy study of the sorption of cationic polymers on hair / S.T.A. Regismond, Y.-M. Heng, E.D. Goddard, and F.M. Winnik — Small-angle neutron scattering on neutral and cationic guar galactomannan / M.R. Gittings, J. Lal, P.J. Dérian, and C. Marques — Applications of gel permeation chromatography with multi-angle light scattering to the characterization of polysaccharides / D. Richard White, Jr. — Capillary electrophoresis in starch analysis / H.A. Soini and M.V. Novotny.
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Computer-Aided Molecular Design. Applications in Agrochemicals, Materials, and Pharmaceuticals

 Pharmacology  Comments Off on Computer-Aided Molecular Design. Applications in Agrochemicals, Materials, and Pharmaceuticals
Jan 312019
 

Chronicles recent successes in the application of computer-aided molecular design to the development of new agrochemicals, materials, and pharmaceuticals. Provides an overview of many state-of-the-art modeling techniques, including CoMFA, molecular dynamics, de novo ligand design, QSAR, molecular orbital methods, and genetic algorithms. Includes computational studies of pharmacokinetic properties such as transport and metabolism. Describes modeling of interfacial phenomena, including organic and inorganic surfaces.
Content: Current approaches in computer-aided molecular design / Bruce R. Gelin — Molecular modeling and quantitative structure-activity relationship studies in pursuit of highly potent substituted octanoamide angiotensin II receptor antagonists / Donald B. Boyd, Alan D. Palkowitz, K. Jeff Thrasher, Kenneth L. Hauser, Celia A. Whitesitt, Jon K. Reel, Richard L. Simon, William Pfeifer, Sherryl L. Lifer, Kumiko Takeuchi, Vasu Vasudevan, Aaron D. Kossoy, Jack B. Deeter, Mitchell I. Steinberg, Karen M. Zimmerman, Sally A. Wiest, and Winston S. Marshall — Structure-based design of human immunodeficiency virus-1 protease inhibitors : correlating calculated energy with activity / M. Katharine Holloway and Jenny M. Wai — From maps to models : a concerted computational approach to analysis of the structure-activity relationships of amiloride analogues / Carol A. Venanzi, Ronald A. Buono, William J. Skawinski, Thomas J. Busanic, Thomas J. Venanzi, Randy J. Zauhar, and Victor B. Luzhkov — De novo design : ligand construction and prediction of affinity / Tudor I. Oprea, Chris M.W. Ho, and Garland R. Marshall — De novo design of highly diverse structures complementary to enzyme binding sites : application to thermolysin / Regine S. Bohacek and Colin McMartin — Computer-aided design of new drugs based on retrometabolic concepts / Nicholas Bodor and Ming-Ju Huang — Molecular mechanics and dynamics studies on amide-modified backbones in antisense oligodeoxynucleotides / R.M. Wolf, V. Fritsch, A. De Mesmaeker, J. Lebreton, and A. Waldner — Simulations of drug diffusion in biomembranes / Terry R. Stouch, Howard E. Alper, and Donna Bassolino — Genetic algorithm based method to design a primary screen for antirhinovirus agents / E.P. Jaeger, D.C. Pevear, P.J. Felock, G.R. Russo, and A.M. Treasurywala — Semiempirical quantum chemical probes of the mechanism of chorismate mutase / Stephen B. Bowlus — Rational design of novel ergosterol biosynthesis inhibitor fungicides / Charles H. Reynolds and Steven H. Shaber — Design and synthesis of 5,6-dihydro-4H-1,3,4-oxadiazines as potential octopaminergic pesticides / Mark A. Dekeyser, W. Ashley Harrison, Paul T. McDonald, G.W. Angle, Jr., Saad M.M. Ismail, and Roger G.H. Downer — Insect aggregation pheromone response synergized by “host-type” volatiles : molecular modeling evidence for close proximity binding of pheromone and coattractant in Carpophilushemipterus (L.) (Coleoptera : Nitidulidae) / Richard J. Petroski and Roy Vaz — Predicting activity of protoporphyrinogen oxidase inhibitors by computer-aided molecular modeling / Krishna N. Reddy, Ujjana B. Nandihalli, Hee Jae Lee, Mary V. Duke, and Stephen O. Duke — Experimental design in organic synthesis / Lawrence H. Brannigan, Mark V. Grieshaber, and Dora M. Schnur — Use of predictive toxicology in the design of new chemicals / Vijay K. Gombar and Kurt Enslein — Comparison of in vivo and in vitro toxicity tests from co-inertia analysis / James Devillers and Daniel Chessel — Combined use of linear and nonlinear multivariate analyses in structure-activity relationship studies : application to chemoreception / Daniel Domine, James Devillers, Maurice Chastrette, and Jean-Christophe Doré — Comparative quantitative structure-activity relationship : insect versus vertebrate cholinesterase / Corwin Hansch — Effect of tautomeric equilibria on hydrophobicity as measured by partition coefficients / Albert J. Leo — Structural analysis of carbyne network polymers / Scott A. Best, Patricia A. Bianconi, and Kenneth M. Merz, Jr. — Computer simulation of polyelectrolyte adsorption on mineral surfaces / Susan Fitzwater — Simulating the behavior of organic molecules in zeolites / C.M. Freeman, D.W. Lewis, T.V. Harris, A.K. Cheetham, N.J. Henson, P.A. Cox, A.M. Gorman, S.M. Levine, J.M. Newsam, E. Hernandez, and C.R.A. Catlow — Valence bond charge transfer theory for predicting nonlinear optical properties of organic materials / William A. Goddard, III, Daqi Lu, Guanhua Chen, and Joe W. Perry — Theoretical study of the nitriding process on Cr(100), Fe(100), and Ni(100) surfaces / Hansong Cheng, David B. Reiser, Paul M. Mathias, Kenneth Baumert, and Sheldon W. Dean, Jr. — Computational analysis of azine-N-oxides as energetic materials / James P. Ritchie — Genetic algorithmic approach for computer-aided molecular design / Venkat Venkatasubramanian, King Chan, and James M. Caruthers.
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Pharmacological Control of Calcium and Potassium Homeostasis: Biological, Therapeutical, and Clinical Aspects

 Pharmacology  Comments Off on Pharmacological Control of Calcium and Potassium Homeostasis: Biological, Therapeutical, and Clinical Aspects
Jan 182019
 

As the number of drugs acting on calcium and potassium channels grows, there is a need for a continuous reappraisal of the cellular machinery controlling them. The present volume provides an update on the basic knowledge, the molecular targets of the two channels, and the importance the drugs that bind them have as pharmacological tools and therapeutic agents. This work was presented at the 6th International Symposium on PHARMACOLOGICAL CONTROL OF CALCIUM AND POTASSIUM HOMEOSTASIS: BIOLOGICAL, THERAPEUTICAL, AND CLINICAL ASPECTS, in Florence (Italy) on October 4-6, 1994. Because of the recent advances in the field, discussions on potassium channels were included for the first time. At least six classes of voltage-dependent calcium channels have been defined based on their physiological and pharmacological properties. Among them, L-type channels, mediating long lasting currents, are better characterized. Calcium homeostasis within the cell is not only regulated by calcium channels; intracellular calcium stores, in particular a pool contained in the lumen of specialized areas of the endoplasmic reticulum, are rapidly exchanged with the cytoplasm and playa key role in the control of calcium homeostasis. This area, however, has not yet been exploited from a therapeutic point of view. Potassium channels are present in virtually every cell type, excitable and nonexcitable, and are distinguished by structural, biophysical, and pharmacological criteria. Different classes including voltage-gated, ligand-gated, AP-sensitive, and G-protein coupled among others, have been defined by their primary regulatory and gating mechanisms.
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Biochemical Pharmacology as an Approach to Gastrointestinal Disorders: Basic Science to Clinical Perspectives (1996)

 Gastroenterology/Hepatology, Pharmacology  Comments Off on Biochemical Pharmacology as an Approach to Gastrointestinal Disorders: Basic Science to Clinical Perspectives (1996)
Jan 152019
 

The Gastrointestinal Section of the International Union of Pharmacology (IUPHAR) was established in 1994 in Montreal, Canada. The establishment of the GI Section recognizes the international progress of gastrointestinal pharmacology, including basic and human studies. The Gastrointestinal Section of IUPHAR organized the first symposium, Biochemical Pharmacology as an Approach to Gastrointestinal Diseases: from Basic Science to Clinical Perspectives, on 10-12 October, 1995, in Pécs, Hungary. The main topics were: Gastrointestinal secretory and excretory fuctions Gastrointestinal motility Biochemical-pharmacological mechanisms in neural and hormonal actions involved in GI functions Main normal and pathological biochemical mechanisms in GI functions GI mucosal injury and protection Molecular mechanisms of premalignant and malignant diseases in GI tract Use of isolated cells and cell cultures in bioochemical-pharmacological studies to approach GI diseases. The presented papers are published in this book.
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Pharmacological Therapies for Peripheral Vascular Disease

 Pharmacology  Comments Off on Pharmacological Therapies for Peripheral Vascular Disease
Jan 042019
 


Patients with peripheral vascular disease (PVD) are at increased risk of death when compared with age-matched healthy controls. They are also, whether symptomatic or not, six times more likely to die within ten years when compared to patients without the disease.

This excess mortality exists even if coronary artery disease is not clinically present, and makes the treatment of PVD a highly important and pressing topic. In this fully up-to-date text, Dr. Mukherjee and his excellent team of twenty-one contributors present the reader with all of the currently available clinical information for treating PVD patients effectively.

 

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http://nitroflare.com/view/9B939CDC6C673CC/1841844578.pdf

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Implications of Psychopharmacology to Psychiatry: Biological, Nosological, and Therapeutical Concepts

 Pharmacology, Psychiatry  Comments Off on Implications of Psychopharmacology to Psychiatry: Biological, Nosological, and Therapeutical Concepts
Jan 022019
 

The discovery of chlorpromazine 40 years ago and of other compounds for the specific treatment of psychiatric disorders had marked influence on clinical psychiatry and basic neuroscience. Since then, the development of psychopharmacology and theories of psychiatric disorders have become closely interrelated. On the occasion of the 70th birthday of Hanns Hippius – one of the pioneers of clinical psychopharmacology – leading experts in this field and related disciplines met to present and discuss their views and theories on psychiatric disorders. Future perspectives of drug development, genetic research in psychiatry, nosological and diagnostic concepts, and strategies for more specific treatment of various psychiatric disorders were presented. This was a unique occasion for most of the prominent and leading experts worldwide to contribute to this book. The reader is given broad insight into the research and clinical perspectives of psychiatry.
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The Pharmacology of Pain

 Pharmacology  Comments Off on The Pharmacology of Pain
Jan 012019
 

Pain is a symptom of many clinical disorders, afflicts a large proportion of the population and is largely treated by pharmacological means. However, the two main classes of drugs used are the opioids and the non-steroidal anti­ inflammatory drugs, drugs that have a long history. The last decade has seen remarkable advances in our understanding of some of the pharmacological bases of pain and analgesia and this book aims to reflect these rapid changes in our understanding of pain mechanisms. One impetus to these scientific advances has been dialogue and interactions between scientists and clinicians; as a result we now has a number of animal models of clinical pain states, to mimic certain aspects of clinical pathophysiological pain states. Molecular aspects of receptors and the synthesis of tools for probing receptor function have also been rapid growth areas. A number of controlled clinical studies using novel licensed drugs have also resulted from recent research, offering hope to certain patients with severe intractable pain. However, we desperately need the pharmaceutical industry to develop new drugs based on these novel targets for analgesic therapy. This book attempts to provide an overview of the important areas of the pharmacology of pain. This book, although providing an account of the pharmacology of pain transmission and its control based on the underlying anatomical organization and physiological responses, does not attempt to cover these latter two areas.
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Plant Polyphenols 2: Chemistry, Biology, Pharmacology, Ecology

 Pharmacology  Comments Off on Plant Polyphenols 2: Chemistry, Biology, Pharmacology, Ecology
Dec 292018
 

rd This book has been developed from the proceedings of the 3 Tannin Confer­ ence honoring Professor Edwin Haslam, Department of Chemistry, University of Sheffield, for his efforts and outstanding contributions to the field of plant polyphe­ nols. The meeting was held in Bend, Oregon, July 20-25, 1998, with the objective of promoting collaboration between chemists and biologists to improve our under­ standing of the biological significance and to expand possibilities for use of plant polyphenols. Special efforts were made to summarize current research on the in­ nd fluence ofthese compounds on human health. As in our 2 Tannin Conference held in Houghton, Michigan, June 1991, we strove to build the “international” charac­ ter of this meeting and were rewarded by an attendance of over 150 guests from 23 countries who enjoyed more than 50 lectures and 60 presentations. Our thanks go to all those who contributed to our meeting. A special thanks is extended to Professor G. Wayne McGraw, Department of Chemistry, Louisiana College, Pineville, Louisiana, who served as the financial manager of our meeting. He, his wife Bobbie McGraw, and Helen Hemingway worked hard to make this meeting run as smoothly as possible. We also would like to thank the Bend Chamber of Commerce, Central Oregon Community College, The Riverhouse, Interstate Tours, Wanderlust Tours, and the people of Bend for welcoming our group to Central Oregon.
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