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Dec 152016
 

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Dec 152016
 

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Dec 122016
 

Human Drug Targets: A Compendium for Pharmaceutical Discovery


By (author): Edward D. Zanders

The identification of drug targets in a given disease has been central to pharmaceutical research from the latter half of the 20th century right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the most important aspects of drug discovery – the identification of suitable protein and RNA targets prior to the creation of drug development candidates.

The first part of the book consists of introductory chapters that provide the background to drug target discovery and highlight the way in which these targets have been organised into online databases. It also includes a user’s guide to the list of entries that forms the bulk of the book.

Since this is not designed to be a compendium of drugs, the emphasis will be on the known (or speculated) biological role of the targets and not on the issues associated with pharmaceutical development. The objective is to provide just enough information to be informative and prompt further searches, while keeping the amount of text for each of the many entries to a minimum.

Human Drug Targets will prove invaluable to those drug discovery professionals, in both industry and academia, who need to make some sense of the bewildering array of online information sources on current and potential human drug targets. As well as creating order out of a complex target landscape, the book will act as an ideas generator for potentially novel targets that might form the basis of future discovery projects. 

List Price: $150.00 USD
New From: $108.18 USD In Stock
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Dec 112016
 

Systems Pharmacology and Pharmacodynamics (AAPS Advances in the Pharmaceutical Sciences Series)


While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.
List Price: $239.00 USD
New From: $205.60 USD In Stock
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Dec 112016
 

Litt’s D.E.R.M. Drug Eruptions and Reactions Manual, 20th Edition (Drug Eruption Reference Manual)


By (author): Jerome Z. Litt, Neil Shear

Relied upon by dermatologists and medical practitioners internationally for its unparalleled practical focus on adverse effects and cutaneous reactions, this text is the essential quick-reference tool for patient care and drug safety. The reaction data for this new 20th edition is compiled from the companion website, which is updated continuously, and includes prescription and over-the-counter drugs as well as biologics, supplements, and other medical products?with tens of thousands of adverse drug reactions, eruptions, and reaction patterns. The text notes the number of peer-reviewed references for reaction listings, the reported incidence of a reaction, and clinically important and potentially serious interactions between drugs.

List Price: $179.00
New From: $1,226.68 USD In Stock
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Dec 112016
 

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Dec 052016
 

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Dec 042016
 

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Dec 042016
 

Developing Drug Products in an Aging Society: From Concept to Prescribing (AAPS Advances in the Pharmaceutical Sciences Series)


This book aims to address the major aspects of future drug product development and therapy for older adults, giving practical guidance for the rational product and clinical development and prescribing of drug products to this ever growing segment of the population. With authors coming from key “aging” markets such as Europe, the USA, China and Japan, the book will provide valuable information for students, scientists, regulators, practitioners, and other healthcare professionals from academia, industry and regulatory bodies.
List Price: $279.00 USD
New From: $193.47 USD In Stock
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Dec 032016
 

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