Diagnostic Lymph Node Pathology, Third Edition

 Pathology  Comments Off on Diagnostic Lymph Node Pathology, Third Edition
Feb 262019
 


Diagnostic Lymph Node Pathology presents a logical and systematic approach to lymph node biopsies and guides general pathologists and haematopathologists alike through the maze of differential diagnoses, enabling them to reach an accurate diagnosis.

The book is presented in an easy-to-read format and contains boxes for quick reference detailing the clinical, morphological, immunohistochemical, and genetic features of each entity. Thoroughly revised, the third edition also includes more than 300 high-quality histological colour photographs along with updated references.

This edition covers both classical and less well-known features of individual disease processes. It is a valuable guide for both professionals and trainees.

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Structure-Function Relationships of Human Pathogenic Viruses

 Pathology  Comments Off on Structure-Function Relationships of Human Pathogenic Viruses
Feb 162019
 

Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.
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Molecular Basis of Oxidative Stress: Chemistry, Mechanisms, and Disease Pathogenesis

 Pathology  Comments Off on Molecular Basis of Oxidative Stress: Chemistry, Mechanisms, and Disease Pathogenesis
Feb 162019
 

Focusing on the molecular and chemical bases of oxidative stress, which can cause cancer as well as cardiovascular and neurodegenerative diseases, Molecular Basis of Oxidate Stress discusses the role of free radicals in disease, diagnosis, and therapeutics. Written by recognized leaders in the field, the book provides in-depth knowledge about the mechanisms of oxidative stress and damage, free radical chemistry, and the role of free radicals in disease, diagnosis, and therapeutics.

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Molecular Detection of Human Parasitic Pathogens

 Pathology  Comments Off on Molecular Detection of Human Parasitic Pathogens
Feb 052019
 

Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized for rapid, sensitive, and specific characterization of parasites.

The large number of original and modified molecular protocols that have been developed over the years creates a dilemma for those attempting to adopt the most appropriate protocol for streamlined identification and detection of human pathogenic organisms of interest. Part of a four-volume collection, Molecular Detection of Human Parasitic Pathogens provides a reliable and comprehensive resource on the molecular detection and identification of major human parasitic pathogens.

This volume contains expert contributions from international scientists involved in human parasitic pathogen research and diagnosis. Following a similar format throughout, each chapter includes:

• A brief review on the classification, biology, epidemiology, clinical features, and diagnosis of an important pathogenic parasitic genus/group
• An outline of clinical sample collection and preparation procedures and a selection of representative stepwise molecular protocols
• A discussion on further research needs relating to improved diagnoses of major human parasitic pathogens
This versatile reference on molecular detection and identification of major human parasitic pathogens is an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in parasite characterization. It is also suitable as a textbook for undergraduate and graduate students majoring in parasitology.

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Advances in Surgical Pathology: Mesothelioma: Mesothelioma

 Pathology, Surgery  Comments Off on Advances in Surgical Pathology: Mesothelioma: Mesothelioma
Jan 282019
 

Advances in Surgical Pathology: Mesothelioma, a volume in the Advances in Surgical Pathology series, features chapters on current and impending changes in the field with an emphasis on practical issues, recent developments, and emerging concepts.

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Neonatal Hematology: Pathogenesis, Diagnosis, and Management of Hematologic Problems

 Hematology, Pathology  Comments Off on Neonatal Hematology: Pathogenesis, Diagnosis, and Management of Hematologic Problems
Jan 282019
 


Neonatal hematology is a fast-growing field, and hematologic problems occur in the majority of sick neonates. Focusing on clinical issues and problem-solving, this is a fully revised and updated revision of a successful practical guide to the pathogenesis, recognition and management of hematologic problems in the neonate.

The second edition begins with chapters on the history of neonatal hematology, hematopoiesis, and the immunologic system. Subsequent sections are devoted to erythrocyte disorders, platelet disorders, leucocyte disorders, immunologic disorders and hemostatic disorders. New to this edition are an expanded coverage of neonatal oncology, cord blood utilization, neonatal screening, prenatal diagnosis and hyperbilirubinemia. Written by practising physicians specializing in pediatric hematology, neonatology, immunology, pediatric infectious disease and transfusion medicine, this is an essential text for pediatric hematologists, NICU specialists, neonatologists and neonatal nurse practitioners.

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Study Guide to Accompany Pathophysiology: Concepts of Altered Health States

 Pathology, Physiology  Comments Off on Study Guide to Accompany Pathophysiology: Concepts of Altered Health States
Jan 282019
 

The learning activities in this “Study Guide” promote understanding of the complex concepts involved in physiology and pathophysiology. The wide range of learning and review tools includes short-answer, matching, fill-in-the-blank, multiple-choice, and labeling exercises. The book helps students review the essentials, clarify complex concepts, apply what has been learned from the text, and improve exam performance. An answer key with rationales is included.

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Auto-Inflammatory Syndromes: Pathophysiology, Diagnosis, and Management

 Pathology  Comments Off on Auto-Inflammatory Syndromes: Pathophysiology, Diagnosis, and Management
Jan 252019
 

This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophysiology and examine the underlying inductive and effector mechanisms and therapies that relate to each auto-inflammatory disorder at the genetic, molecular, cellular, and epidemiologic levels. The book also discusses the research behind auto-inflammatory disorders to offer detailed clinical guidelines regarding diagnostic techniques, treatment plans, and advice on how to best transition pediatric patients into adult treatment. This is an invaluable reference on auto-inflammatory syndromes for clinicians and researchers in pediatric and adult rheumatology and immunology.
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Spinal Cord Monitoring: Basic Principles, Regeneration, Pathophysiology, and Clinical Aspects

 Pathology, Physiology  Comments Off on Spinal Cord Monitoring: Basic Principles, Regeneration, Pathophysiology, and Clinical Aspects
Jan 232019
 

During the last decades, research on spinal cord has attracted a great deal of attention because of problems such as sensory-motor and autonomic dysfunctions associated with traumatic and other injuries. Recording of spinal cord evoked potentials is one of the most promising approaches to understand the spinal cord function. However, the details of the evoked potentials and their significance in various pathological conditions are not yet fully characterized. This book summarizes new findings in the field of electrophysiology and relates this knowledge to pathology and regeneration research. It is the first one which deals in great detail with various ways to monitor spinal cord function in experimental and clinical situations. It provides an up-to-date knowledge regarding spinal cord bioelectrical activity and its modification with pharmacological agents and covers new aspects of regeneration studies, particularly the role of myelin associated inhibitory molecules. A section is devoted to clinical studies dealing with electrical activity, pathology, and current therapeutic measures. This volume will be useful both to basic and clinical neuroscientists engaged in the field of neurology, neurophysiology, neurochemistry, neurosurgery, neuropathology, and related disciplines in order to understand basic functions of the spinal cord and to stimulate further research in this rapidly advancing field.
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Prion Diseases: Diagnosis and Pathogenesis

 Pathology  Comments Off on Prion Diseases: Diagnosis and Pathogenesis
Jan 232019
 

A comprehensive understanding of the biology of prion diseases is crucial for risk assessment as regards both humans and animals. To further the communication of the current knowledge and the exchange of diagnostic technologies in the scientific community, a symposium on the ‘Characterization and Diagnosis of Prion Diseases’ was held from September 23-25, 1999 in Tübingen, Germany. The overwhelming interest and the participation of more than 500 scientists from 26 countries made this symposium the largest meeting ever held in the field. In this Supplementum to Archives of Virology twenty-six invited speakers comprehensively present their data on the pathogenesis of prion diseases in humans and animals, on molecular mechanisms involved in the transmissibility across species barriers, on animal and in-vitro models currently available for the detection and quantification of infectivity and on the characterization of prion strains. This selection attempts to reflect the current state of the art, but cannot possibly represent the whole spectrum of research in the prion field.
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