Scars to Pearls: A Medical Healing and Spiritual Journey Through the Phases of Malignant Melanoma Stage IIIA Skin Cancer with..

 Oncology  Comments Off on Scars to Pearls: A Medical Healing and Spiritual Journey Through the Phases of Malignant Melanoma Stage IIIA Skin Cancer with..
Oct 022018
 

So when facing a life threatening trial, how do you refuel the transformation needed to replenish the balance in life itself? What do you lean on, trust on, or hope on? I am a recently retired OB-GYN-Infertility nurse practitioner of almost thirty years in the field, and I experienced delivering a spectrum of diagnoses in my area of expertise. There were the ‘good news’ moments with joy, success, and cure. But there will be moments we witness overwhelming pain and the devastating news of death.

The shoe is on the other foot now for me. I am the patient with metastatic melanoma skin cancer and not the provider, a very uncomfortable and humbling place for me. Sometimes the biggest battle fought isn’t the cancer, but the emotional battle we suddenly find ourselves in. We are not prepared for this emotional turmoil or how to deal with it. The journey I experienced and now share with you had its difficulties, filled with approximately fifty appointments, two surgeries, hospitalization and therapies, but life continues. If you have recently been diagnosed with cancer, I know you are scared; I certainly was.

Because in the beginning when you first hear the news, you immediately wonder: ‘How is this all going to end?’ The journey has only just begun and we are already wondering: ‘How it’s all going to play out?’ I know all the questions you are asking yourself, for I am the patient now and my perspective has changed. I can feel the uncertainty of your courage and strength to proceed through the demands of appointments, diagnostic testing, surgeries, pain, and treatments

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Bacterial Therapy of Cancer: Methods and Protocols

 Oncology  Comments Off on Bacterial Therapy of Cancer: Methods and Protocols
Sep 292018
 

This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.
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Cancer Epigenetics for Precision Medicine: Methods and Protocols

 Oncology  Comments Off on Cancer Epigenetics for Precision Medicine: Methods and Protocols
Sep 282018
 

This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

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Advanced and Emerging Technologies in Radiation Oncology Physics

 Oncology, Radiology  Comments Off on Advanced and Emerging Technologies in Radiation Oncology Physics
Sep 282018
 

This new book educates readers about new technologies before they appear in hospitals, enabling medical physicists and clinicians to prepare for new technologies thoroughly and proactively, and provide better patient care once new equipment becomes available. Emerging technologies in imaging, treatment planning, treatment delivery, dosimetry and informatics are all discussed. The book is divided into three parts: recently developed technologies available for practice; technologies under development nearing completion; and technologies in an early stage of development that could have potential radiotherapy applications.

Features:

Introduces emerging technologies in imaging, treatment planning, treatment delivery, dosimetry and informatics
The advantages and limitations of each technology in clinical settings are discussed
Recommendations on how to adopt the technologies are provided
Suggestions on how to prepare quality assurance are provided as needed
Critiques and improvement points are provided for researchers

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Prostate Cancer: Principles and Practice

 Oncology  Comments Off on Prostate Cancer: Principles and Practice
Sep 272018
 


This volume is the first interdisciplinary medical text on prostate cancer. More than 50 chapters cover all aspects of diagnosis and screening and all forms of accepted treatments of the prostate, with emphasis on the retention of sexual and physiological function.Highlights of the book include the most exhaustive coverage currently available of advanced androgen-sensitive and androgen-refractory disease. An introductory chapter discusses the impact of advances in genetic understanding of prostate cancer on clinical practice.
A Brandon-Hill recommended title.

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Obesity, Fatty Liver and Liver Cancer

 Oncology  Comments Off on Obesity, Fatty Liver and Liver Cancer
Sep 272018
 

This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.
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Risky Genes: Genetics, Breast Cancer, and Jewish Identity

 Genetics, Oncology  Comments Off on Risky Genes: Genetics, Breast Cancer, and Jewish Identity
Sep 252018
 

Ashkenazi Jews have the highest known population risk of carrying specific mutations in the high-risk breast cancer genes, BRCA1 and BRCA2. So what does it mean to be told you have an increased risk of genetic breast cancer because you are of Ashkenazi Jewish origin? In a time of ever-increasing knowledge about variations in genetic disease risk among different populations, there is a pressing need for research regarding the implications of such information for members of high-risk populations. Risky Genes provides first-hand intimate descriptions of women s experiences of being Jewish and of being at increased risk of genetic breast cancer. It explores the impact this knowledge has on their identity and understanding of belonging to a collective. Using qualitative data from high-risk Ashkenazi women in the UK, this book elucidates the importance of biological discourses in forging Jewish self-identity and reveals the complex ways in which biological and social understandings of Jewish belonging intersect. In Risky Genes, Jessica Mozersky reflects upon and offers new insight into the ongoing debates regarding the implications of genetic research for populations, and of new genetic knowledge for individual and collective identity. The book will be of interest to students and scholars of sociology, anthropology, Jewish studies, medical genetics, medical ethics, religious studies, and race and ethnic studies.
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Stem Cell Oncology

 Oncology  Comments Off on Stem Cell Oncology
Sep 212018
 

Stem cell research is one of the fascinating areas of contemporary biology, but, as with many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates discoveries. Research on stem cell treatment continues to advance knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms. The most important potential application of human stem cells is the generation of cells and tissues that could be used for cell-based therapies, especially oncology.

The Faculty of Medicine, Universitas Sumatera Utara, collaborated with the center of excellence and innovation (Pusat Unggulan Inovasi /PUI). The Stem Cell center of the Universitas Sumatera Utara (USU) organized an International Conference. The International Stem Cell and Oncology Conference (ISCOC) 2017 was a comprehensive academic conference in the field of stem cell and oncology research and also tropical medicine and related scientific topics.

We expect Stem Cell Oncology will benefit academics and practitioners in the field of health sciences in Indonesia.

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Anticancer Plants: Clinical Trials and Nanotechnology: Volume 3

 Oncology  Comments Off on Anticancer Plants: Clinical Trials and Nanotechnology: Volume 3
Sep 202018
 

Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer.
Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their value in the treatment of cancer and various other infectious diseases, and several common anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants.

Unfortunately, many of these anticancer plants have become endangered due to ruthless and irresponsible harvesting practices. Hence, there is a need to conserve these species and to propagate them on a large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology could be adopted to produce these anticancer compounds without the need for cultivation. A better grasp and continuing exploration of these isolated molecules and products could provide a powerful alternative means of reducing cancer risk.

“Anticancer Plants: Volume 3, Clinical Trials and Nanotechnology” provides a timely review of concepts and experimental data on the application of anticancer plants and their compounds in clinical trials, and on the use of nanotechnology in cancer therapy.

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Anticancer Plants: Mechanisms and Molecular Interactions: Volume 4

 Oncology  Comments Off on Anticancer Plants: Mechanisms and Molecular Interactions: Volume 4
Sep 202018
 

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies.
In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

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