Breast Cancer Risk Reduction and Early Detection

 Oncology  Comments Off on Breast Cancer Risk Reduction and Early Detection
Mar 032020
 

Breast Cancer Risk Reduction and Early Detection provides an in-depth overview of the factors of breast cancer risk and what health care providers and individuals can do to impact the risk of breast cancer in their patient or themselves. Many books address breast cancer in general or focus on treatment; few focus on prevention and early detection, including current practices and new strategies in: epidemiology, primary prevention, chemoprevention, surgical prevention, breast specific (physical examination, imaging, intraductal) and systemic screening and early detection. Written by experts in their fields, this book is a resource to researchers, clinicians and the broad group of health care providers. It is a source of accurate information for individuals to use to reduce risk of new or recurrent breast cancer and to apply best practices for early detection.
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An Omics Perspective on Cancer Research

 Oncology  Comments Off on An Omics Perspective on Cancer Research
Mar 022020
 

Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics.This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research.This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research.Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.
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Cancer

 Oncology  Comments Off on Cancer
Mar 022020
 

The last decade has seen a dramatic shift in anticancer drug research towards agents that aim to selectively target key regulatory and signaling processes known to drive tumorigenesis. A number of these newer agents have now been introduced into clinical practice. This volume reviews advances in cancer chemotherapy research over the last 10 years and will be of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy, growth factor inhibition, survival signaling, cell cycle inhibition, anti-angiogenics and anti-nvasives. Each chapter aims to cover the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
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Clinical Care and Rehabilitation in Head and Neck Cancer

 Oncology  Comments Off on Clinical Care and Rehabilitation in Head and Neck Cancer
Mar 022020
 

Malignancies involving structures of the head and neck frequently impact the most fundamental aspects of human existence, namely, those functions related to voice and speech production, eating, and swallowing. Abnormalities in voice production, and in some instances its complete loss, are common following treatment for laryngeal (voice box) cancer. Similarly, speech, eating, and swallowing may be dramatically disrupted in those where oral structures (e.g., the tongue, jaw, hard palate, pharynx, etc.)
are surgically ablated to eliminate the cancer. Consequently, the range and degree of deficits that may be experienced secondary to the treatment of head and neck cancer (HNCa) are often substantial. This need is further reinforced by the Centers for Disease Control and Prevention who have estimated that the number of individuals who will be newly diagnosed with HNCa will now double every 10 years. This estimate becomes even more critical given that an increasing number of those who are newly diagnosed will be younger and will experience the possibility of long-term survival post-treatment.

Contemporary rehabilitation efforts for those treated for HNCa increasingly demand that clinicians actively consider and address multiple issues. Beyond the obvious concerns specific to any type of cancer (i.e., the desire for curative treatment), clinical efforts that address physical, psychological, communicative, and social consequences secondary to HNCa treatment are essential components of all effective rehabilitation programs. Comprehensive HNCa rehabilitation ultimately seeks to restore multiple areas of functioning in the context of the disabling effects of treatment. In this regard, rehabilitation often focuses on restoration of function while reducing the impact of residual treatment-related deficits on the individual’s overall functioning, well-being, quality of life (QOL), and ultimately, optimize survivorship.

Regardless of the treatment method(s) pursued for HNCa (e.g., surgery, radiotherapy, chemoradiation, or combined methods), additional problems beyond those associated with voice, speech, eating and swallowing frequently exist. For example, post-treatment changes in areas such as breathing, maintaining nutrition, limitations in physical capacity because surgical reconstruction such as deficits in shoulder functioning, concerns specific to cosmetic alterations and associated disfigurement, and deficits in body image are common. Those treated for HNCa also may experience significant pain, depression, stigma and subsequent social isolation. Concerns of this type have led clinicians and researchers to describe HNCa as the most emotionally traumatic form of cancer. It is, therefore, essential that clinicians charged with the care and rehabilitation of those treated for HNCa actively seek to identify, acknowledge, and systematically address a range of physical, psychological, social, and communication problems. Efforts that systematically consider this range of post-treatment sequelae are seen as critical to any effort directed toward enhanced rehabilitation outcomes. Actively and purposefully addressing post-treatment challenges may increase the likelihood of both short- and long-term rehabilitation success in this challenging clinical population.

Current information suggests that successful clinical outcomes for those with HNCa are more likely to be realized when highly structured, yet flexible interdisciplinary programs of care are pursued. Yet contemporary educational resources that focus not only on management of voice, speech, eating, and swallowing disorders, but also address issues such as shoulder dysfunction due to neck dissection, the significant potential for cosmetic alterations can offer a much broader perspective on rehabilitation. Contemporary surgical treatment frequently involves reconstruction with extensive procedures that require donor sites that include both soft tissue from a variety of locations (e.g., forearm, thigh, etc.), as well as bone (e.g., the scapula). Collectively, resources that address these issues and many other concerns and the resultant social implications of HNCa and its treatment can serve to establish a comprehensive framework for clinical care. Consequently, providing a highly specialized and comprehensive educational resource specific to HNCa rehabilitation is currently needed. The proposed edited book is designed to address this void in a single authoritative resource that is also accessible to the clinical readership. Integral to this proposed book is information that guides clinical approaches to HNCa rehabilitation, in addition to offering emphasis on the direct impact of changes in voice, speech, and swallowing and the impact of such losses on outcomes.

Finally, while several other published sources currently exist (see attached list), the emphasis of these books is directed either toward the identification and diagnosis of malignant disease, clinical and surgical pathology, associated efforts directed toward biomedical aspects of cancer and its treatment, or those with a focus on a single clinical problem or approach to rehabilitation. Therefore, the content of the proposed multi-chapter text centers on delivering a systematically structured, comprehensive, and clinically-oriented presentation on a range of topics that will provide readers at a variety of levels with a strong, well-integrated, and empirically driven foundation to optimize the clinical care of those with HNCa.

The primary audience for this textbook is undergraduate and graduate-level students in Speech-Language Pathology, as well as practitioners, especially hospital-based practitioners, in Speech-Language Pathology; other key audiences include junior and senior level otolaryngology residents and fellows, translational researchers in head and neck cancer, related medical specialists (e.g., radiation oncology), oncology nurses, and potentially other rehabilitation professionals such as occupational therapists, counseling psychologists, social workers, and rehabilitation counselors.

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https://nitroflare.com/view/A4C61490FC8036D/3030047016.epub

https://nitroflare.com/view/00B308DF225653A/3030047016.pdf

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https://filejoker.net/c1shfty8qbew

https://filejoker.net/l162yxu1obir

 

 

 

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Pediatric Oncology Nursing

 Nursing, Oncology, Pediatrics  Comments Off on Pediatric Oncology Nursing
Mar 012020
 

This comprehensive clinical handbook for nurses in pediatric hematology/oncology, authored by nurse experts from the United Kingdom and North America, contains in-depth information regarding pathophysiology, diagnosis, treatment, advanced assessment, and interventions.

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https://nitroflare.com/view/CD45B5B60EB9A5F/3540408517.pdf

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Compact Clinical Guide to Cancer Pain Management: An Evidence-Based Approach for Nurses

 Nursing, Oncology  Comments Off on Compact Clinical Guide to Cancer Pain Management: An Evidence-Based Approach for Nurses
Feb 292020
 

Awarded second place in the 2013 AJN Book of the Year Awards in the Palliative Care and Hospice category

This book provides many options for pain management in cancer patients, including pharmacological and nonpharmacological options,…[and] is well organized and easy to navigate. Score: 92, 4 Stars.–Doody’s Medical Reviews

Overall, [this book] is a comprehensive and wide-ranging text that, as proclaimed on the cover, is evidence-based and fully referenced. Practitioners and students alike will find it useful, and it deserves a place on the library shelf where people from a wide range of backgrounds can gain access.”–International Journal of Palliative Nursing

“[This] text is full of ‘clinical pearls’ based on [the authors’] extensive clinical experience with effective and ineffective pain management interventions√ñThe scope of the content in this text is extremely comprehensive√ñnewer content on the effect of opioid polymorphisms, cancer pain emergencies, myofascial pain, and chronic pain in cancer survivors places this text at the forefront in terms of cutting-edge issues in cancer pain management.”

Christine Miaskowski, RN, PhD, FAAN
Professor and Associate Dean for Academic Affairs
American Cancer Society Clinical Research Professor
Sharon A. Lamb Endowed Chair in Symptom Management Research
Department of Physiological Nursing
University of California, San Francisco, CA
From the Foreword

Although the prevalence of uncontrolled cancer pain remains unnecessarily high, research has indicated that 90% of cancer patients with pain can be successfully treated with standard therapies. This concise yet extremely comprehensive guide to managing cancer pain will enable nurses on the front lines of pain assessment and management to incorporate effective strategies into their daily practice. It offers quick access to current evidence-based guidelines for busy nurses and nurse practitioners working in all oncology care settings. To facilitate quick information retrieval, the text is designed in a consistently organized, bulleted format with highlighted key information and tools for assessment and standardized treatment. It also serves as an important review for the ONS and HPNA certification exam.

This book focuses on all aspects of cancer pain, including assessment and screening tools, pharmacologic and nonpharmacologic treatment options, current national guidelines for pain management, regional anesthesia techniques, patient-controlled anesthesia, and epidural pain management. It also includes updated information on the effect of opioid polymorphisms, cancer pain emergencies, myofascial pain, and chronic pain in cancer survivors. The book covers palliative care and end-of-life pain management, especially for patients who have symptoms that are not managed. Information on chronic pain conditions such as neuropathic pain in cancer and the use of adjuvant medications for pain control are included, along with special treatment options for addiction and substance abuse in the cancer population. The text additionally provides information on managing pain with difficult-to-treat populations.
Key Features:

– Provides current, evidence-based information on all aspects of cancer pain management
– Includes important new guidelines on using a combination of pain management scales for optimal pain assessment and management
– Describes interventional techniques for managing severe pain situations
– Organized for speedy information retrieval

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https://nitroflare.com/view/17B1B81DADBCBB1/Compact_Clinical_Guide_to_Cancer_Pain_Management_An_Evidenc.pdf

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Therapy Response Imaging in Oncology

 Oncology, Radiology  Comments Off on Therapy Response Imaging in Oncology
Feb 262020
 

This book is a detailed guide to therapy response imaging in cancer patients that fully takes into account the revolutionary progress and paradigm shift in treatment approaches for advanced disease. The opening chapters describe the role of imaging as a “common language” for tumor response evaluation in oncology and address challenges and strategies in the era of precision cancer therapy and cancer immunotherapy. Practical pitfalls are discussed, with emphasis on the importance of approaching cancer as a systemic disease and the need for increased awareness of drug toxicity due to novel therapies. Therapy response imaging in a wide range of cancer types is then comprehensively described and illustrated, using a disease-specific approach. A concluding section focuses on emerging approaches and future directions, including radiomics/radiogenomics, co-clinical imaging, and molecular and functional imaging. Therapy Response Imaging in Oncology will be of high value for radiologists, nuclear medicine physicians, and oncologists. It will also be of interest to cancer care providers and oncology trial investigators.

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https://nitroflare.com/view/1912261868C37A9/3030311708.pdf

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The Bethesda Handbook of Clinical Oncology

 Oncology  Comments Off on The Bethesda Handbook of Clinical Oncology
Feb 262020
 

The Bethesda Handbook of Clinical Oncology is a clear, concise and comprehensive reference book for the busy clinician to use in his or her daily patient encounters. It focuses less on etiology, pathophysiology, and epidemiology, and considerably more on practical clinical information. Cancer management information is presented in a reader-friendly format that offers a comprehensive review of each disease along with the most commonly used treatment regimens, including chemotherapy dosing and schedules.
Features:
– Clear, concise, complete reference book for busy clinician for daily patient management
– User-friendly formatting – tables, algorithms, charts, bullet points
– Contributors all from NIH (or they trained there)
– Great for board exams
– Organized by body region
New to this edition:
– Add a chapter on Cancer Genetics and expand the Basics of Genomics for practicing oncologists to include the clinically relevant molecular tests.
– Major addition will be to add about 5 board review question and answers per chapter – more than 200 board review questions
– New treatment regimens added to all appropriate chapters
– New clinical trial data added on treatment
– More chemotherapeutic agents added (including newer regimens and dosages)

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https://nitroflare.com/view/FCCA9CE86E2E118/The_Bethesda_Handbook_of_Clinical_Oncology.pdf

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Retroviruses and Insights into Cancer

 Oncology  Comments Off on Retroviruses and Insights into Cancer
Feb 262020
 

This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.
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Laryngeal Cancer: Clinical Case-Based Approaches

 Oncology  Comments Off on Laryngeal Cancer: Clinical Case-Based Approaches
Feb 262020
 

Ongoing advances in innovative technologies have improved the diagnosis and treatment of laryngeal cancer, resulting in more optimal oncologic and functional patient outcomes. Laryngeal Cancer: Approach Based on Clinical Cases, by distinguished head and neck surgeon Rogério R. Dedivitis and internationally recognized coeditors, is a comprehensive reference that presents multiple options for similar lesions. Contributions from a diverse group of globally renowned subspecialists reflect the multidisciplinary treatment of laryngeal cancer.

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https://nitroflare.com/view/B50E222B46CC5B7/1684200016.pdf

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