Practical Radiation Oncology

 Oncology, Radiology  Comments Off on Practical Radiation Oncology
Dec 122019
 

This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning.
In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source.

Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

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Resistance to Targeted Therapies Against Adult Brain Cancers

 Neurology/Neurosurgery, Oncology  Comments Off on Resistance to Targeted Therapies Against Adult Brain Cancers
Dec 122019
 

This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

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Kidney Cancer: Recent Advances in Surgical and Molecular Pathology

 Oncology, Pathology, Surgery  Comments Off on Kidney Cancer: Recent Advances in Surgical and Molecular Pathology
Dec 112019
 

This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification.
Written by experts in the field, chapters contain an updated review of important pathologic parameters mandated for diagnosis and reporting with emphasis on updated information regarding new developments in this interesting field. Numerous high-resolution color images aptly illustrate the various pathologic entities and their features as outlined in the text section along with tables that highlight the differential diagnoses and salient ancillary features.
Kidney Cancer serves as a quick reference for all categories of readers alike, and provides up-to-date information on renal tumor pathology, radiology and management that are required in daily practice.

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Ethical Issues in Pediatric Hematology/Oncology

 Hematology, Oncology, Pediatrics  Comments Off on Ethical Issues in Pediatric Hematology/Oncology
Dec 112019
 

This book identifies the various ethical challenges that arise in pediatric hematology/oncology and provides the necessary tools to overcome these challenges. Aiming to expand upon and strengthen providers’ knowledge and experience in pediatric health care ethical issues, the text positions providers to be beneficial resources to faculty, staff, patients, and families within their institution.
It presents a multidisciplinary approach to sound ethical practices that is necessary to effectively care for these patients and their families. The book reviews the principles of ethical decision-making, the unique difficulties in using children as research subjects, common ethical conundrums involved in providing end-of-life care, and general moralities of professional practice.
Written by experts in their fields, Ethical Issues in Pediatric Hematology/Oncology is an innovative and valuable resource for clinicians, practitioners, and trainees who work in the field of pediatric hematology/oncology.

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Molecular Pathology of Gynecologic Cancer

 Ob/Gynae, Oncology, Pathology  Comments Off on Molecular Pathology of Gynecologic Cancer
Dec 102019
 

This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.
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Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future

 Oncology  Comments Off on Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future
Dec 102019
 

Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multi-modality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology.
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Treatment and Management of Cancer in the Elderly (Basic and Clinical Oncology)

 Oncology  Comments Off on Treatment and Management of Cancer in the Elderly (Basic and Clinical Oncology)
Dec 092019
 

Building upon the strengths of the popular reference, Cancer in the Elderly, this guide outlines novel approaches in the identification and management of cancer in geriatric populations by world-renowned experts on the topic. Presenting new trends and strategies in surgery, radiation therapy, and chemotherapy, this source presents a multidisciplinary and best-practices approach to the optimization of cancer care for the elderly and collects the most recent findings gleaned from prevention, adjuvant, neo-adjuvant, and treatment research.
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Signaling Pathways in Cancer Pathogenesis and Therapy

 Oncology  Comments Off on Signaling Pathways in Cancer Pathogenesis and Therapy
Dec 082019
 

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.
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Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

 Oncology  Comments Off on Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach
Dec 072019
 

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

 Oncology  Comments Off on Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics
Dec 072019
 

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.

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