Communicating with Cancer Patients

 Oncology  Comments Off on Communicating with Cancer Patients
Jun 052019
 

Published in association with European Society of Medical Oncology, this volume is designed for trainee oncologists, oncology nurses, and those working with cancer patients on a day-to-day basis.

Focusing on the “soft skills” required in communicating with patients, the book includes topics such as the aetiology of cancer, diagnosis and staging, and explaining the purpose of treatment, including chemotherapy, hormone treatment, and immunological and gene-based therapies. It also discusses patient support groups, monitoring remission, and relapse. The book is written by UK oncologists but has international application

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Caveolins in Cancer Pathogenesis, Prevention and Therapy

 Oncology  Comments Off on Caveolins in Cancer Pathogenesis, Prevention and Therapy
Jun 042019
 

Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. They have been shown to play an important role in the pathogenesis of multiple cancers. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.
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QuickFACTS Advanced Cancer

 Oncology  Comments Off on QuickFACTS Advanced Cancer
Jun 032019
 

Although advanced cancer is not likely to be cured, it can frequently be controlled, and this book emphasizes that all patients should be well-informed decision-makers in planning their own treatment. Covering everything from risk factors to living well after cancer treatment, this pocket-sized reference provides critical questions to ask your healthcare team, is updated with the latest patient treatment guidelines, and includes an advanced dictionary of cancer-related terms.
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Atlas of Procedures in Surgical Oncology With Critical, Evidence-based Commentary Notes

 Oncology  Comments Off on Atlas of Procedures in Surgical Oncology With Critical, Evidence-based Commentary Notes
Jun 032019
 


This unique book presents a series of concisely written technical notes on common procedures in surgical oncology. Each operation is illustrated with pictures framing precise technical points. The book is accompanied by a CD-ROM that includes video clips of the procedures.

Written by top European experts, this volume will provide an invaluable resource for young surgical oncologists to familiarize with technical details, develop a critical approach and expand their surgical skills. It will also be a useful source of reference for medical oncologists, radiologists, radiotherapists and nurses, as well as final-year medical students.

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Cancer and its Management, 7 edition

 Oncology, Uncategorized  Comments Off on Cancer and its Management, 7 edition
May 312019
 

Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management.

The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revised new editions of this standard and well-received cancer text for audiences in the UK and abroad. Oncology is a very rapidly changing speciality, with many new treatments and even treatment modalities coming on stream with bewildering speed. Besides a thorough general updating of the text, figures, and tables, the new seventh edition adds a new chapter on Molecular Targeted Therapy, making the book 30 chapters in total. This accessible and practical resource is invaluable to trainees and specialists alike in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine.

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Methionine Dependence of Cancer and Aging: Methods and Protocols

 Oncology  Comments Off on Methionine Dependence of Cancer and Aging: Methods and Protocols
May 302019
 

This book explores the methionine dependence of cancer and its effects on aging, a great story of science that is not widely known. The chapters in this book describe the discovery of methionine dependence of cancer; the molecular basis for the increased methionine demand of cancer cells and tumors; the clinical application of methionine dependence of cancer in PET imaging with [11C]methionine; the development of methioninases as cancer drugs; the anti-aging and anti-diabetes effects of methionine restriction; and the future of targeting methionine in the body for the elimination of cancer and for the extension of a healthy life-span. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Methionine Dependence of Cancer and Aging: Methods and Protocols is an important resource for researchers and scientists wishing to pursue this exciting and vital area of study.”

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The Cancer Chronicles: Unlocking Medicine’s Deepest Mystery

 Oncology  Comments Off on The Cancer Chronicles: Unlocking Medicine’s Deepest Mystery
May 232019
 

When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.

Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body.

Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

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Precision Radiation Oncology

 Oncology, Radiology  Comments Off on Precision Radiation Oncology
May 232019
 

by Bruce G. Haffty (Author), Sharad Goyal (Author)

Precision medicine is a rapidly-evolving field in the management of cancer. The use of novel molecular or genetic signatures in local-regional management is still in its infancy. Precision Radiation Oncology demystifies this state-of-the-art research and technology.

By describing current existing clinical and pathologic features, and focusing on the ability to improve outcomes in cancer using radiation therapy, this book discusses incorporating novel genomic- or biology-based biomarkers in the treatment of patients moving radiation oncology into precision/personalized medicine. Precision Radiation Oncology provides readers with an overview of the new developments of precision medicine in radiation oncology, further advancing the integration of new research findings into individualized radiation therapy and its clinical applications

About the Author
BRUCE HAFFTY, M.D. is an international expert in breast radiation oncology. He is a professor and chairman in the Department of Radiation Oncology at Rutgers Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, and Rutgers Cancer Institute of New Jersey. He also serves as Chief of Staff of the Rutgers Cancer Institute.

SHARAD GOYAL, M.D. is a professor and division chief of Radiation Oncology in the Department of Radiology at the George Washington University School of Medicine and Health Sciences. He is a board-certified radiation oncologist whose clinical practice is primarily focused on breast and brain cancers.

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Multiscale modeling of cancer : an integrated experimental and mathematical modeling approach

 Oncology  Comments Off on Multiscale modeling of cancer : an integrated experimental and mathematical modeling approach
May 082019
 

The correct functioning of the mammalian brain depends on the integrated activity of myriad neuronal and non-neuronal cells. Discrete areas serve discrete functions, and dispersed or distributed communities of cells serve others. Throughout, these networks of activity are under the control of neuromodulatory systems. One goal of current neuroscientific research is to elucidate the precise methods by which these systems operate, especially during normal conscious behaviours and processes. Mircea Steriade and Denis Paré describe the neuronal properties and networks that exist within and between the cortex and two important sub-cortical structures: the thalamus and amygdala. The authors explore the changes in these properties, covering topics including morphology, electrophysiology, architecture and gating; and comparing regions and systems in both normal and diseased states. Aimed at graduates and postdoctoral researchers in neuroscience “Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field”–Provided by publisher. Machine generated contents note: Part I. Theory: 1. Introduction; 2. Biological background; 3. Continuum tumor modeling: single phase; 4. Analysis and calibration of single-phase continuum tumor models; 5. Continuum tumor modeling: multiphase; 6. Discrete cell modeling; 7. Hybrid continuum-discrete models; 8. Numerical schemes; Part II. Applications: 9. Continuum tumor modeling: a multidisciplinary approach; 10. Agent-based cell modeling: application to breast cancer
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Imaging in Pediatric Oncology

 Oncology, Pediatrics, Radiology  Comments Off on Imaging in Pediatric Oncology
Apr 302019
 


This book, co-authored by an internationally acclaimed team of experts in the field of pediatric oncologic imaging, provides a comprehensive update on new advances in diagnostic imaging as they relate to pediatric oncology. In contrast to other oncologic imaging texts focusing on the radiology of specific tumors, this book emphasizes the important fundamentals of imaging that every child with a new or treated malignancy receives. Guidance is provided on the selection and use of appropriate imaging techniques, with individual chapters devoted to each of the major cross-sectional imaging modalities used in the detection and follow-up of pediatric cancers, including PET-CT, PET-MRI, whole-body MRI, and diffusion-weighted MRI. Additional nuclear medicine techniques are addressed, and detailed attention is paid to more advanced areas of practice such as contrast-enhanced ultrasound, pediatric interventional radiology techniques, radiation treatment planning, and radiation dose considerations (ALARA). Other areas covered include screening of children with cancer predisposition syndromes, treatment related complications, potential pitfalls during neuro-oncologic imaging, and the risks and benefits inherent in post-therapy surveillance imaging.

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