Hormone Therapy and Castration Resistance of Prostate Cancer

 Oncology  Comments Off on Hormone Therapy and Castration Resistance of Prostate Cancer
May 292018
 

This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged.
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Prostate Cancer Survivorship

 Oncology  Comments Off on Prostate Cancer Survivorship
May 292018
 


This book provides information on a range of issues related to prostate cancer survivorship, including; psychosexual care, health related quality of life, treatment, follow-up care, new psychosexual pathways, and acute and chronic co-morbidities. The book also covers the needs and challenges in survivorship care, the requirements of care, the future of survivorship care, and role of patient conferences.
This book aims to give oncologists, urologists, and specialist nurses help in how to manage patients in the prostate cancer survivorship phase. This guidance is based on real life experiences handling prostate cancer survivorship, and is developed further through utilising the views of both health care professionals and patients.

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http://nitroflare.com/view/2E0A5974C9E6E0E/3319653571.epub

http://nitroflare.com/view/B8FFCAD8C8CF3B2/3319653571.pdf

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Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects

 Oncology  Comments Off on Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects
May 292018
 

This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their understanding of the relevance of the cells that constitute the ovary, which is of vast significance in comprehending the occurrence mechanism of ovarian tissue and ovarian cancer. In this way the book covers a wide range of fields concerned with the ovary. This work benefits not only gynecologists and obstetricians, but also basic researchers in the field of stem cell biology and all clinicians who are involved in the management of fertility preservation or ovarian cancer.

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http://nitroflare.com/view/D1EB1C95B4DE40C/9811079404.epub

http://nitroflare.com/view/F27089CDD54D318/9811079404.pdf

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Oncologic Emergencies

 Emergency, Oncology  Comments Off on Oncologic Emergencies
May 282018
 

· Covers full range of oncologic emergencies in patients with cancer and survivors
· Written for busy clinicians in emergent and urgent care settings
· Key practice points included in each chapter

This new resource on managing oncologic emergencies is directed at all health care professionals who care for patients with cancer or survivors. Edited and written by clinician-experts at The University of Texas MD Anderson Cancer Center, the book covers the full range of oncologic emergencies, from cardiac and neurologic to orthopedic to hematologic, and addresses important palliative care, ethical, and Emergency Department considerations.
Chapters are structured with busy clinicians in emergent and urgent settings in mind, and each chapter concludes with a series of key practice points and a list of suggested readings for those who wish to delve deeper into a subject.
For any clinician facing the increasing number of patients who experience an oncologic emergency, this is an up-to-date, clinically focused, and authoritative resource.

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A Practical Guide to Skin Cancer

 Dermatology, Oncology  Comments Off on A Practical Guide to Skin Cancer
May 262018
 

Skin cancer is the most common malignant neoplasm, and with the increasing regularity of such tumors comes the need for a practical guide for medical professionals to reference for diagnosis, management, and treatment. This book covers everything from the epidemiology of the skin cancer, clinical presentation with clinical photographs, diagrams of the most common anatomical locations, to histological descriptions, special stains/tests for diagnosis, and a treatment algorithm in chart form. A Practical Guide to Skin Cancer offers brief and succinct chapters with pertinent references, as well as high quality color photographs, diagrams, tables, and charts.
Written for dermatologists, dermatology residents, and oncologists, this book allows for the reader to quickly and easily obtain the information regarding a tumor’s clinical presentation, patient evaluation and treatment algorithms, proving essential for every physician who encounters these tumors in their daily practice.

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http://nitroflare.com/view/4A8A5199CAF3EE7/3319749013.epub

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Breast Cancer Husband: How to Help Your Wife (and Yourself) during Diagnosis, Treatment and Beyond

 Oncology  Comments Off on Breast Cancer Husband: How to Help Your Wife (and Yourself) during Diagnosis, Treatment and Beyond
May 252018
 

A unique guide, like none other on the market-packed with medical information, practical tips, psychological insight, and coping strategies–to help men help the women they love through this trying time

When Marc Silver became a breast cancer husband three years ago, he learned firsthand how frightened and helpless the breast cancer husband feels. He searched in vain for a book that would give him the information and advice he so desperately sought. Now this award-winning journalist has compiled just the kind of emotionally supportive and useful resource that he wished he had been able to consult-to give men the tools they need to help their wives, their families, and themselves through this scary, uncertain time.

In his years as a consumer journalist and veteran of the News You Can Use staff at U.S. News & World Report, Marc Silver learned what kind of information and advice on medical crises readers found most valuable. He draws on that experience as he covers in depth all the issues couples coping with breast cancer will have to face during diagnosis, treatment, and beyond.

Highlights include: 
• The shared experiences of other breast cancer husbands
• Guidance from top cancer doctors in the country
• Advice on when, how, and what to tell your young children
• Tips on coping with radiation and chemotherapy
• A candid discussion of sex and intimacy following breast cancer surgery

More than 200,000 women are diagnosed with cancer each year in the United States. At last, with this book, the men who love them have a road map to help them through a difficult and unprecedented journey.

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Cytotoxic Drug Resistance Mechanisms (Methods in Molecular Medicine)

 Oncology  Comments Off on Cytotoxic Drug Resistance Mechanisms (Methods in Molecular Medicine)
May 252018
 

There is now a range of cytotoxic drugs that have considerable clinical usefulness in producing responses in tumors and even, in a small proportion of cases, cure. However, the acquisition of drug resistance is a major clinical problem and is perhaps the main limiting factor in successful treatment of cancer. Thus, a tumor initially sensitive to chemotherapy will, in the majority of cases, eventually recur as a resistant tumor, which will then progress. Much of our understanding of drug resistance mechanisms comes from the study of tumor cell lines grown in tissue culture. We now understand many of the – lecular mechanisms that can lead to a cell acquiring resistance to antic- cer drugs; however, we still do not know which mechanism(s) are those most relevant to the problem of clinical drug resistance. Indeed, given that many of the cytotoxic anticancer drugs were discovered by random screening, it is – clear what features give a clinically useful anticancer drug a sufficient the- peutic index to be of value. The aim of Cytotoxic Drug Resistance Mechanisms is to provide pro- cols that are appropriate for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumor samples. Tumor cell lines have been enormously useful as experimental models of drug resistance mechanisms, however they have limitations and we need to address the relevance of such mechanisms in patients’ tumors. Examining drug resistance in tumors is much more problematic than in cell lines.
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Molecular Analysis Of Cancer (Methods In Molecular Medicine)

 Oncology  Comments Off on Molecular Analysis Of Cancer (Methods In Molecular Medicine)
May 252018
 

Leading researchers describe in step-by-step detail their best state-of-the art molecular techniques for elucidating the biochemical processes associated with human cancer. Among the techniques presented for identifying chromosomal rearrangements are fluorescent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), microsatellite analysis, PCR and RT-PCR, and DNA fingerprinting. Additional methods include SSCP, DGGE, the nonisotopic RNase cleavage assay, and the protein truncation assay and DNA sequencing for identifying mutations.

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Ultrasound Assessment in Gynecologic Oncology

 Ob/Gynae, Oncology, Radiology  Comments Off on Ultrasound Assessment in Gynecologic Oncology
May 222018
 

This innovative guide will help gynecologists or gynecologic surgeons to monitor the staging and progress of oncology treatment. An international expert here shows what office ultrasound can be used to achieve, how it correlates with other clinical findings, and how it can be integrated as necessary with other modalities and with the latest technological advances and developments in the field.
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Understanding Breast Cancer Genetics

 Genetics, Oncology  Comments Off on Understanding Breast Cancer Genetics
May 212018
 

Health & Sickness – Consumer Health –>
This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually.
Why are some women more vulnerable than others? The interplay between genetics and environment is suspected.
Thus this book for general readers will help them understand the genetic bases of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on.
Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered.
Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman’s understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included.
Barbara T. Zimmerman did her graduate work in experimental pathology and her post-doctoral research in the cellular and molecular processes of disease. Widely published, she is the manager of the Denver-based firm Biomedical Communication and Consulting.

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