Alzheimers Disease: Advances for a New Century

 Neurology/Neurosurgery  Comments Off on Alzheimers Disease: Advances for a New Century
Mar 272019
 

This volume is a companion to the highly successful book published in association with the Journal of Alzheimers Disease (JAD) on the centennial of Alzheimers discovery: Alzheimers Disease: A Century of Scientific and Clinical Research. Instead of looking back, this collection, Alzheimers Disease: Advances for a New Century, will look forward. Using scientometric analysis the most promising developments since the Alzheimer Centennial in 2006 have been substantiated. While prior trends and advances in genetics, amyloid-, tau, neuropathology, and oxidative stress continue as active areas, emergent areas impacting the transition from normal cognition to Alzheimers disease such as diagnostic imaging, biomarkers, metabolism, and lifestyle (areas conceived only a few years ago) now dominate the debate. Invited contributors have summarized their landmark publications identified by our analysis and have put them into perspective, explaining the impetus behind the work, the contribution of the results to the field, and who played a role in the work.

IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields.

Some of the areas we publish in:

-Biomedicine
-Oncology
-Artificial intelligence
-Databases and information systems
-Maritime engineering
-Nanotechnology
-Geoengineering
-All aspects of physics
-E-governance
-E-commerce
-The knowledge economy
-Urban studies
-Arms control
-Understanding and responding to terrorism
-Medical informatics
-Computer Sciences

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Fast Facts: Multiple Sclerosis, 3 edition

 Neurology/Neurosurgery  Comments Off on Fast Facts: Multiple Sclerosis, 3 edition
Mar 252019
 

Rapid advances in multiple sclerosis (MS) research have produced diagnostic achievements and new treatments that are helping clinicians diagnose and potentially treat MS in the earliest phases of the disease. It is with this sense of optimism that the authors of Fast Facts: Multiple Sclerosis have detailed the latest developments for use in clinical practice by all members of the multidisciplinary team. Highlights include: * A refreshingly readable account of the latest evidence on disease pathomechanisms * A concise overview of investigations, diagnostic criteria and red flags for differential diagnoses * A holistic approach to all signs and symptoms, and proactive relapse management * An evidence-based analysis of all the latest disease-modifying drugs, including when to treat, choice of drug and risk versus benefit * A detailed outline of emerging therapies * Case histories that will guide treatment decisions * Special considerations for MS during pregnancy, and in children and the elderly Addressing the issues that will make the biggest differences to patient care, Fast Facts: Multiple Sclerosis is essential reading for all healthcare professionals involved in the care of patients with this complex disease.

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The Making of a Neuromorphic Visual System

 Neurology/Neurosurgery  Comments Off on The Making of a Neuromorphic Visual System
Mar 222019
 

The reader is presented an approach to the construction of a visual system, which is behaviorally, computationally and neurally motivated. The central goal is to characterize the process of visual categorization and to find a suitable representation format that can successfully deal with the structural variability existent within visual categories. It does not define such representations a priori but attempts to show directions on how to gradually work towards them. The book reviews past and existent theories of visual object and shape recognition in the fields of computer vision, neuroscience and psychology. The entire range of computations is discussed, as for example contour extraction in retinal circuits, orientation determination in cortical networks, position and scale independence of shape, as well as the issue of object and shape representation in a neural substrate. Region-based approaches are discussed and are modeled with wave-propagating networks. It is demonstrated how those networks operate on gray-scale images. A completely novel shape recognition architecture is proposed that can recognize simple shapes under various degraded conditions. It is discussed how such networks can be used for constructing basic-level object representations. It is envisioned how those networks can be implemented using the method of neuromorphic engineering, an analog electronic hardware substrate than can run neural computations in real-time and with little power.
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PET/CT in Brain Disorders

 Neurology/Neurosurgery  Comments Off on PET/CT in Brain Disorders
Mar 212019
 

This well-illustrated pocket book offers up-to-date guidance on the clinical and research applications of PET/CT in the most common neurological and neuro-oncological disorders. The opening chapters cover the pros and cons of widely used radiological imaging techniques, scanners, and radiopharmaceuticals, with emphasis on the state of the art hybrid modalities, primarily PET/CT but also PET/MRI. Helpful information is provided on the clinical and research tracers used in neurodegenerative diseases, movement disorders, epilepsy and brain tumours. These four killers are then discussed in detail, highlighting the role of PET/CT and targeted tracers in their assessment and in radiotherapy planning. In addition, the clinical applications of PET/MRI are considered. Throughout, many images are included to better explain the diseases and the role of hybrid imaging, and the final chapter presents a large sample of teaching cases and files that will assist in daily clinical practice. The book has been compiled under the auspices of the British Nuclear Medicine Society. It will be an excellent asset for nuclear medicine physicians, radiologists, radiographers, neurologists and neurosurgeons.
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Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders

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Mar 212019
 

by Sanjeev Kumar Gupta (Author, Editor), Srinivasan Venkatesan (Editor), S.P. Goswami (Editor), Rajeev Kumar (Editor)

Neurodevelopmental disorders encompass a group of conditions that can typically manifest during early childhood. These include intellectual disabilities, communication disorders, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), specific learning disorder (SLD), and motor disorders. Early identification and assessment can be a valuable tool in determining diagnosis, prognosis, functional abilities, and formulating clinical intervention for both children and adults with neurodevelopmental disorders.

Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders is an essential reference source that discusses and disseminates contributions covering recent trends in diagnosis, assessment, and intervention techniques. Featuring research on topics such as clinical linguistics, neural connectivity, and animal-assisted therapy, this book is ideally designed for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neural and developmental disorder identification and strategies for clinician support and therapies

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Computational Neuroendocrinology (Wiley-INF Masterclass in Neuroendocrinology Series)

 Endocrinology/Metabolism/Diabetes Mellitus, Neurology/Neurosurgery  Comments Off on Computational Neuroendocrinology (Wiley-INF Masterclass in Neuroendocrinology Series)
Mar 212019
 

Neuroendocrinology with its well defined functions, inputs, and outputs, is one of the most fertile grounds for computational modeling in neuroscience. But modeling is often seen as something of a dark art. This book aims to display the power of modeling approaches in neuroendocrinology, and to showcase its potential for understanding these complex systems.
A recurring theme in neuroendocrinology is rhythms. How are rhythms generated, and what purpose do they serve? Are these two questions inextricably intertwined?
This book is written for innocents, presuming no math beyond high school or computing beyond calculators. It seeks to lead the curious into the thinking of the modeler, providing the tools to the reader to understand models, and even develop their own, giving life to paper diagrams. The diverse chapters, from ion channels to networks, systems, and hormonal rhythms, each tell the story of a model serving to join the hard won dots of experimentation, mapping a new understanding, and revealing hidden knowledge.

• Written by a team of internationally renowned researchers
• Both print and enhanced e-book versions are available
• Illustrated in full colour throughout
This is the fourth volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA

• Written by a team of internationally renowned researchers
• Both print and enhanced e-book versions are available
• Illustrated in full colour throughout
This is the fourth volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA

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Neurology and Clinical Neuroanatomy on the Move

 Anatomy, Neurology/Neurosurgery  Comments Off on Neurology and Clinical Neuroanatomy on the Move
Mar 202019
 

The Medicine on the Move series provides fully flexible access to subjects across the curriculum in a unique combination of print and mobile formats ideal for the busy medical student and junior doctor. Neurology and Clinical Neuroanatomy on the Move provides sharply focused content equally suited to those studying the subject for the first time or revisiting it during exam preparation.

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Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier

 Neurology/Neurosurgery  Comments Off on Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier
Mar 192019
 

by Engineering, and Medicine National Academies of Sciences (Author), Health and Medicine Division (Author), Board on Health Sciences Policy (Author), Forum on Neuroscience and Nervous System Disorders (Author), Clare Stroud (Editor), Noam I. Keren (Editor), Lisa Bain (Editor)

Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the blood—brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop

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Neuropsychopharmacology and Therapeutics

 Neurology/Neurosurgery, Pharmacology  Comments Off on Neuropsychopharmacology and Therapeutics
Mar 182019
 

Neuropsychopharmacology is a relatively new subject area in the neurosciences. It is a field of study that describes the effects of drugs from the molecular to the behavioural level and requires integration and synthesis of knowledge from various disciplines including neuroanatomy, physiology, molecular biology, pharmacology and the behavioural sciences. The principal aims of this book are to provide students with a clear understanding of CNS disorders, and an appreciation of how basic and clinical research findings can be translated into therapeutics.

After an introduction to the subject area, the remaining chapters are focused on reviewing the main psychiatric and neurological disorders that are covered in most courses. They are discussed in terms of their clinical symptoms, epidemiology, pathology, aetiology, underlying neurobiological and neurochemical mechanisms, pharmacotherapy, adjunctive non–pharmacological treatments, and clinical outcomes. Each chapter of the book is a stand–alone chapter and is written in a clear, accessible style.

Written by an author with many years teaching and research experience, this textbook will prove invaluable for students of pharmacology, pharmacy and the medical sciences needing a truly integrated introduction to this exciting field.

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Absolute Epilepsy and EEG Rotation Review: Essentials for Trainees

 Neurology/Neurosurgery  Comments Off on Absolute Epilepsy and EEG Rotation Review: Essentials for Trainees
Mar 172019
 

This book contains the most essential information needed for an epilepsy/ EEG rotation. Chapters are formatted with bullet points and feature clinical pearls. Concise and easy-to-read, this quick reference provides neurology residents, clinical neurophysiology and epilepsy fellows, and other clinicians with the most critical information in epilepsy and EEG in a simplified, yet comprehensive format. Divided into two sections, the book first covers the diagnosis, characteristics, and treatment of epilepsy. The second section focuses on EEG placement, procedures, and patterns in various neurological disorders.
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